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	题名	作者	年代	出处	被引量
1	Lower Bifidobacteria counts in both duodenal mucosa-associated and fecal microbiota in irritable bowel syndrome patients显示文摘AIM: To determine the composition of both fecal and duodenal mucosa-associated microbiota in irritable bowel syndrome (IBS) patients and healthy subjects using molecular-based techniques. METHODS: Fecal and duodenal mucosa brush samples were obtained from 41 IBS patients and 26 healthy subjects. Fecal samples were analyzed for the composition of the total microbiota using fluorescent in situ hybridization (FISH) and both fecal and duodenal brush samples were analyzed for the composition of bif idobacteria using real-time polymerase chain reaction. RESULTS: The FISH analysis of fecal samples revealed a 2-fold decrease in the level of bifidobacteria (4.2 ± 1.3 vs 8.3 ± 1.9, P < 0.01) in IBS patients compared to healthy subjects, whereas no major differences in other bacterial groups were observed. At the species level, Bifidobacterium catenulatum levels were significantly lower (6 ± 0.6 vs 19 ± 2.5, P < 0.001) in the IBS patients in both fecal and duodenal brush samples than in healthy subjects.CONCLUSION: Decreased bifidobacteria levels in both fecal and duodenal brush samples of IBS patients compared to healthy subjects indicate a role for microbiotic composition in IBS pathophysiology.	Angèle PM Kerckhoffs Melvin Samsom Michel E van der Rest Joris de Vogel Jan Knol Kaouther Ben-Amor Louis MA Akkermans	2009	World Journal of Gastroenterology2009，15，23：	33
2	Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice显示文摘AIM:To investigate the therapeutic effect of Schistosoma mansoni(S.mansoni) soluble worm proteins on gastrointestinal motility disturbances during experimental colitis in mice. METHODS:Colitis was induced by intrarectal injection of trinitrobenzene sulphate(TNBS) and 6 h later,mice were treated ip with S.mansoni proteins.Experiments were performed 5 d after TNBS injection.Inflammationwas quantified using validated inflammation parameters. Gastric emptying and geometric center were measured to assess in vivo gastrointestinal motility.Peristaltic activity of distal colonic segments was studied in vitro using a modified Trendelenburg set-up.Cytokine profiles of T-lymphocytes isolated from the colon were determined by real time reverse transcriptase-polymerase chain reaction. RESULTS:Intracolonic injection of TNBS caused severe colitis.Treatment with S.mansoni proteins significantly ameliorated colonic inflammation after 5 d.TNBS did not affect gastric emptying but significantly decreased the geometric center and impaired colonic peristaltic activity 5 d after the induction of colitis.Treatment with S.mansoni proteins ameliorated these in vivo and in vitro motility disturbances.In addition,TNBS injection caused a downregulation of effector T cell cytokines after 5 d,whereas a S.mansoni protein effect was no longer observed at this time point. CONCLUSION:Treatment with S.mansoni proteins attenuated intestinal inflammation and ameliorated motility disturbances during murine experimental colitis.	Nathalie E Ruyssers Benedicte Y De Winter Joris G De Man Natacha D Ruyssers Ann J Van Gils Alex Loukas Mark S Pearson Joel V Weinstock Paul A Pelckmans Tom G Moreels	2010	World Journal of Gastroenterology2010，16，6：	11
3	Spinal mechanisms contribute to analgesia prodused by epidural sufentanil clmbined with bupivacaine far postoperative analgesia显示文摘	Joris J L Jacob E A Sessler D I	2003	Anesth Analg2003，97，：	1
4	Evidence for biotype-specific effectsof bovine viral diarrhea virus on biological responses in acutely infected calves显示文摘	Joris E Douart A	1998	Journal of General Virology1998，79，：	1
5	Characterizzation of the immune response of cattle against non-cytopathic and cytopathic biotype of bovin viral diarrhea显示文摘	Douart A Joris E	1997	Gen Virol1997，78，：	1
6	Pain after laparoscopic cholecystectomy:characteristics and effect of intraperitoneal bupivacaine显示文摘	Joris J Thiry E Paris P	1995	Anesth Analg1995，81，：	1
7	Pain after laparoscopic cholecystectomy:characteristics and effect of intraperitoneal bupivacaine显示文摘	Joris J Thiry E Paris P	1995	Anesth Analg1995，81，2：	1
8	Pain after laparoscopic cholecystectony; characteristics and effect of intraperitoneal bupivaeaine 显示文摘	Joris J Thiry E Paris P	1995	Anesth Analg1995，81，：	1
9	Shrimp white spot virus in the western hemisphere 显示文摘	Jory D E Dixon H M	1999	Aquaculture1999，25，：	1
10	Pain after laparoscopic cholecystectomy:Characteristics and effect of intraperitoneal bupivacaine显示文摘	Joris J Thiry E Pacis Po	1995	Anesth Analg1995，81，：	1
11	Development of fluidized bed combustion-an overview of trends,performance and cost显示文摘	JORIS KOORNNEEF MARTIN JUNGINGER ANDR(E)FAAI	2007	Progress in Energy and Combustion Science2007，33，1：	1
12	Pain after laparoscopic cholecystectomy:characteristics and effect of intraperitoneal bupivacaine显示文摘	Joris J Thiry E Paris C	1995	Anesth Analg1995，81，：	1
13	PrenataltestinginICSIpregnancies: incidedce of chromosomal anomalies in 1586 karyotypes and relation to sperm parameters显示文摘	Bonduelle M VanAssche E Joris H	2002	Human Repred2002，17，10：	1
14	Pain after laparoscopic choleeystectomy: Characteristics and effect of intraperitoneal bupivacaine 显示文摘	Joris j Thiry E Paris P	1995	Anesth Analg1995，81，2：	1
15	Pain after laparoscopic cholecystectomy:characteristics and effect of intraperitoneal bupivacaine显示文摘	Joris J Thiry E Paris P	1995	Anesth Analg1995，81，：	1
16	显示文摘	Etter E Donado P Jori F	2006	Ann N Y Acad Sci2006，1081，：	1
17	Pain after laparoscopic cholecystectomy:characteristics and effect of intraperitoneal bupivacaine 显示文摘	Joris J Thiry E Paris P	1995	Anesth Analg1995，81，2：	1
18	Pain after laparoscopic cholecystectomy: characteristics and effect of intraperitoneal bupivacaine显示文摘	Thiry E Paris P	1995	Anesth Analg1995，81，：	1
19	Ultrastructural studies on the mechanism of the photodynamic therapy of tumors显示文摘	Milanesi C Biolo R Reddi E Jori G	1987	Photochem Photobiol 19871987，，：	1
20	EGF-responsive rat neural stem cells:molecular follow-up of neuron and astrocyte differentiation in vitro显示文摘	Jori FP Galderisi U Piegari E	2003	J Cell Physio12003，195，2：	1

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