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| 1 | Mitochondrial DNA A1555G mutation screening using a testing kit method and its significance in preventing aminoglycoside-related hearing loss显示文摘To report a new screening method for mitochondrial DNA 1555A→G mutation and the results of genotype analysis in 19 maternal inherited deafness pedigrees. Method Five hundred and forty-six non-syndromic neuro-sensory hearing loss patients were tested for 1555A→G mutation using a new compact testing kit, which allows clear distinction between wild type and 1555 A→G mutated mtDNAs. Results Nineteen subjects among the 546 patients (3.48%) were found to carry mtDNA A1555G mutation. The results were confirmed by sequencing in an ABI 3100 Avant sequencer. Conclusions Maternal inherited deafness families are a frequently seen in outpatient group. The detection of mtDNA 1555 A→G mutation with a low cost, ready to use detection kit is needed and suitable in China for large scale screening and preventive testing before usage of aminoglycoside antibiotics. | LIU Xin,1 DAI Pu,1* HUANG Deliang,1 YUAN Huijun,1 LI Weiming,1 YU Fei,1 ZHANG Xin,1 KANG Dongyang,1 CAO Juyang,1 YANG Weiyan,1 HAN Dongyi,1 JIN Zhengce2, GUAN Minxin3 1. Department of Otolaryngology, Chinese PLA General Hospital, Beijing, China2. Weihai Aomaier Gene Technological CO.,LTD.,Weihai,Shandong 264200, China.3. Division and Program in Human Genetics and Center for Hearing and Deafness Research, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA | 2006 | Journal of Otology2006，1，1： | 7 |
| 2 | The Tibetan Plateau Surface–Atmosphere Coupling System and Its Weather and Climate Effects: The Third Tibetan Plateau Atmospheric Science Experiment显示文摘The Tibetan Plateau(TP) is a key area affecting forecasts of weather and climate in China and occurrences of extreme weather and climate events over the world. The China Meteorological Administration, the National Natural Science Foundation of China, and the Chinese Academy of Sciences jointly initiated the Third Tibetan Plateau Atmospheric Science Experiment(TIPEX-Ⅲ) in 2013, with an 8–10-yr implementation plan. Since its preliminary field measurements conducted in 2013, routine automatic sounding systems have been deployed at Shiquanhe, Gaize, and Shenzha stations in western TP, where no routine sounding observations were available previously. The observational networks for soil temperature and soil moisture in the central and western TP have also been established. Meanwhile, the plateau-scale and regional-scale boundary layer observations, cloud–precipitation microphysical observations with multiple radars and aircraft campaigns, and tropospheric–stratospheric air composition observations at multiple sites, were performed. The results so far show that the turbulent heat exchange coefficient and sensible heat flux are remarkably lower than the earlier estimations at grassland, meadow, and bare soil surfaces of the central and western TP. Climatologically, cumulus clouds over the main body of the TP might develop locally instead of originating from the cumulus clouds that propagate northward from South Asia. The TIPEX-Ⅲ observations up to now also reveal diurnal variations, macro-and microphysical characteristics, and water-phase transition mechanisms, of cumulus clouds at Naqu station. Moreover, TIPEX-Ⅲ related studies have proposed a maintenance mechanism responsible for the Asian 'atmospheric water tower' and demonstrated the effects of the TP heating anomalies on African, Asian, and North American climates. Additionally, numerical modeling studies show that the Γ distribution of raindrop size is more suitable for depicting the TP raindrop characteristics compared to the M–P distribution, the overestimation of sensible heat flux can be reduced via modifying the heat transfer parameterization over the TP, and considering climatic signals in some key areas of the TP can improve the skill for rainfall forecast in the central and eastern parts of China. Furthermore, the TIPEX-Ⅲ has been promoting the technology in processing surface observations, soundings, and radar observations, improving the quality of satellite retrieved soil moisture and atmospheric water vapor content products as well as high-resolution gauge–radar–satellite merged rainfall products, and facilitating the meteorological monitoring, forecasting, and data sharing operations. | Ping ZHAO Yueqing LI Xueliang GUO Xiangde XU Yimin LIU Shihao TANG Wenming XIAO Chunxiang SHI Yaoming MA Xing YU Huizhi LIU La JIA Yun CHEN Yanju LIU Jian LI Dabiao LUO Yunchang CAO Xiangdong ZHENG Junming CHEN An XIAO Fang YUAN Donghui CHEN Yang PANG Zhiqun HU Shengjun ZHANG Lixin DONG Juyang HU Shuai HAN Xiuji ZHOU | 2019 | Journal of Meteorological Research2019，33，3： | 4 |
| 3 | An Operational Precipitable Water Vapor Retrieval Algorithm for Fengyun-2F/VISSR Using a Modified Three-Band Physical Split-Window Method显示文摘The Visible and Infrared Spin-Scan Radiometer(VISSR) onboard the Fengyun-2(FY-2) satellite can provide valuable thermal infrared observations to help create a precipitable water vapor(PWV) product with high spatial and temporal resolutions. The current FY-2/VISSR PWV product in operation is produced by using a traditional two-band physical split-window(PSW) method, which produces low quality results under dry atmospheric conditions. Based on the sensitivity characteristics of FY-2 F/VISSR water vapor channel and two split-window channels to atmospheric water vapor, this study developed a new, robust operational PWV retrieval algorithm for FY-2 F to improve the operational precision of the current PWV product. The algorithm uses a modified three-band PSW method, which adds a scale for the water vapor channel in the improved three-band PSW method. Integrated PWV products from the radiosonde data in 2016 are used here to validate the precision of the PWV retrieved by the modified three-band and traditional two-band PSW methods. The mean bias, root mean square error(RMSE), and correlation coefficient of the PWV retrieved by the modified three-band PSW method are 0.28 mm, 4.53 mm, and 0.969, respectively. The accuracy is much better than the PWV retrieved by the two-band method, whose mean bias, RMSE, and correlation coefficient are 12.67 mm, 29.35 mm, and 0.23. Especially, in mid-or high-latitude regions, the RMSE of the PWV is improved from 10 to 2 mm by changing the inversion in the two-band method to the modified three-band PSW method. Furthermore, the modified three-band PSW results show a better consistency with the radiosonde PWV at any zonal belt and season than the two-band PSW results. This new algorithm could significantly improve the quality of the current FY-2 F/VISSR PWV product, especially at sites where the actual PWV are lower than 15 mm. | Juyang HU Shihao TANG Hailei LIU Min MIN | 2019 | Journal of Meteorological Research2019，33，2： | 3 |
| 4 | Auditory characteristics of noise-exposed memberscrossing age-related groups显示文摘Objective: To report audiological characteristics in a group of noise-exposed crew members on board ships.Methods and materials: Clinical and audiological measurements including pure-tone thresholds, acoustic immittance results and tinnitus questionnaires were collected from both the ship crew members(study subjects) and their land based colleagues(controls).Results: 1) Noise exposed crew members showed not only high frequency, but also low frequency hearing loss; 2) Hearing impairment increased with age, with 65.5% of crew members younger than 50 years showing normal hearing while only 14.9% of those older than 50 years had normal hearing; 3)hearing loss gradually increased with the extension of on board career time; and 4) Most study subjects reported high pitch tinnitus, significantly more than the control group although not significantly different among different age groups.Conclusion: Noise induced hearing impairment from working on board ships shows specific frequency and age characteristics. Understanding these characteristics is important for advancing relevant studies and for effective prevention of noise-induced hearing loss in ship crew members. | Liu Chenqing Ding Daxiong Zhu Yuhua Wang Hongyang Cheng Xiaoting Zhao Zhenhua Cao Juyang Zhai Suoqiang Yu Ning | 2018 | Journal of Otology2018，13，2： | 3 |
| 5 | Extremely low penetrance of deafness associated with the mitochondrial 12S rRNA mutation in 16 Chinese families: Implication for early detection and prevention of deafness显示文摘 | Pu Dai Xin Liu Dongyi Han Yaping Qian Deliang Huang Huijun Yuan Weiming Li Fei Yu Ruining Zhang Hongyan Lin Yong He Youjun Yu Quanzhu Sun Huaiyi Qin Ronghua Li Xin Zhang Dongyang Kang Juyang Cao Wie-Yen Young Min-Xin Guan | 2005 | Biochemical and Biophysical Research Communications2005，，1： | 2 |
| 6 | Camera Calibration with Distortion Models and Accurancy Evaluation 显示文摘 | Weng Juyang Cohen P Herniou M | 1992 | Ransactions on Pattern and Machine Intelligence1992，14，10： | 1 |
| 7 | Camera Calibration with Distortion Models and Accuracy Evaluation显示文摘 | Weng Juyang | 1992 | IEEE Transactions on Pattern Analysis and Machine Intelligence1992，14，10： | 1 |
| 8 | Camera Calibration with Distortion Models and Accuracy Evaluation显示文摘 | Weng Juyang Cohen P Herniou M | 1992 | IEEE Transaction on Pattern Analysis and Machine Intelligence1992，14，10： | 1 |
| 9 | Camera Calibration with Distortion Models and Accuracy Evaluation显示文摘 | Weng Juyang Cohen P Hemiou M | 1992 | IEEE Transactions on Pattern Analysis and Machine Intelligence1992，14，10： | 1 |
| 10 | Incremental online object learningin a vehicular radar radar-vision fusion framework 显示文摘 | JI Zhengping Luciw M WENG Juyang | 2011 | IEEE Transactions on Intelligent Transpor tation Systems2011，12，2： | 1 |
| 11 | Camera Calibration with Distortion Models and Accuracy Evaluation 显示文摘 | Juyang Weng | 1992 | IEEE Transaction on pattern analysis and machine intelligence1992，14，10： | 1 |
| 12 | Camera Calibration with Distortion Models and Accuracy Evaluation显示文摘 | Juyang WENG Paul COHEN Marc HERNION | 1992 | IEEE Transactions analysis and machine intelligence1992，14，10： | 1 |
| 13 | Camera Calibration with Distortion Models and Accuracy Evaluation 显示文摘 | Juyang Weng Paul Cohen Marc Herniou | 1992 | IEEE Translations on Pattern Analysis and Machine Intelligence1992，14，10： | 1 |
| 14 | Camera calibration with distortion models and accuracy显示文摘 | Weng Juyang Cohen P Herniou M | 1992 | Evaluation Tran Part Anal Machme intell1992，14，10： | 1 |
| 15 | Candid covariance-free incremental principal component analysis显示文摘 | WENG Juyang ZHANG Yilu HWANG Wey-Shiuan | 2003 | IEEE Trans on Pattern Analysis and Machine Intelligence2003，25，8： | 1 |
| 16 | Camera calibration with distortion models and accuracy evaluation显示文摘 | Juyang W Paul C Marc H | 1992 | IEEE Transactions on Pattern Analysis and Machine Intelligence1992，14，10： | 1 |
| 17 | Camera calibration with distortion models and accuracy evaluation显示文摘 | WENG Juyang Cohen P Herniou M | 1992 | IEEE Transactions on Pattern Analysis and Machine Intelligence1992，14，10： | 1 |
| 18 | Camera calibration with distortion models and accuracy evaluation显示文摘 | Weng Juyang Cohen P Herniou M | 1992 | IEEE Trans on Pattern Analysis and Michine Intelligence1992，14，10： | 1 |
| 19 | Camera Calibration with Distortion Models and Accuracy Evaluation 显示文摘 | Weng Juyang Cohen Paul Herniou Marc | 1992 | IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE1992，14，10： | 1 |
| 20 | Camera calibration with distortion models and accuracy evaluation显示文摘 | Juyang Weng Paul Cohen | 1992 | IEEE Transactions on Pattern Analysis and Machine Intelligence1992，14，96： | 1 |
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