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| 1 | Insulin sources and types: a review of insulin in terms of its mode on diabetes mellitus显示文摘Insulin is involved in regulation of glucose utilization in the body. Inability of the body to synthesize insulin or human cells resistance to insulin leads to a condition called Diabetes mellitus which is characterized by chronic hyperglycaemia. There are two types of diabetes; type 1 and type 2. Exogenous supply of insulin is needed consistently for type 1diabetes treatment and type 2 diabetes also needs to be cured by the exogenous supply of insulin in advance stages of the disease. These sources have been proved very useful to meet the needs of the patients. However, these insulin types are expensive for the large population of patients in the developing countries. Furthermore, the incidence of diabetes is advancing at an alarming rate. Hence production systems with even higher capabilities of production are desired. Therefore, currently plants are being investigated as alternative production systems. Based on the mode of action of insulin various formulations of insulin have been developed that have different onset of action, peak effect and duration of action according to the needs of the patients. | Kafeel Ahmad | 2014 | Journal of Traditional Chinese Medicine2014，34，2： | 8 |
| 2 | Synergistic antibacterial effect of honey and Herba Ocimi Basilici against some bacterial pathogens显示文摘OBJECTIVE: To evaluate the antibacterial activity of the combination of different honey brands and methanolic fraction of Herba Ocimi Basilici using agar well diffusion assay. METHODS: The antibacterial activity was determined against thirteen pathogenic bacterial clinical isolates including six gram negative(Klebsiella pneumonia, Pseudomonas aeroginosa, Escherichia coli, Salmonella typhi, Salmonella typhimirium, Xanthomonas campestris) and six gram positive strains(Enterococcus faecalis faecalis, Bacillus subtilis, Staphylococcus aureus, Clostridium perfringens type C, Clostridium perfringens type D, Clostridium chauvoei). Agar well diffusion method was used while zones of inhibition were measured with vernier scale. RESULTS: At higher concentration, all the honey brands showed good to significant activity. The highest activity was observed for Hamdard brand honey(27.60±0.40) against Enterococcus faecalis. CONCLUSION: These results revealed that combinations of plant extracts of Herba Ocimi Basilici with honey can be used for the development of potent and novel antibacterial agents. | Ali Talha Khalil Imran Khan Kafeel Ahmad Yusra Ali Khan Momin Khan Muhammad Jaseem Khan | 2013 | Journal of Traditional Chinese Medicine2013，33，6： | 4 |
| 3 | Antibacterial activity of honey in north-west Pakistan against select human pathogens显示文摘OBJECTIVE:To investigate the antimicrobial activity of commercially available honey and raw honey samples in Khyber Pakhtunkhwa,Pakistan,against pathogenic bacterial strains.METHODS:Well diffusion assays were performed to screen pure and diluted honey samples for antibacterial activity against six Gram-negative and six Gram-positive bacterial strains.Zones of inhibition were measured and compared with 10 mg Gentamycin.RESULTS:When honey samples were diluted to20%-70%,the honey samples showed no activity to mild antibacterial activity.The highest antibacterial activity was recorded when 90%and pure undiluted honey samples were tested and compared with a control Gentamycin disc(10 mg).CONCLUSION:Commercially processed honey and raw honey samples from north-west of Pakistan possess good antimicrobial potential. | Ali Talha Khalil Imran Khan Yusra Ali Khan Zabta Khan Shinwari Kafeel Ahmad Jangrez Khan | 2014 | Journal of Traditional Chinese Medicine2014，34，1： | 2 |
| 4 | A Review on Primary and Secondary Controls of Inverter-interfaced Microgrid显示文摘The demand of electricity and environmental issues associated with conventional power generation plants are increasing significantly.Modern technology has transformed the conventional power system through the integration of distributed generation(DG).With the help of modern power electronic technology,the conventional power system is able to support the integration of DGs based on renewable energy sources(RESs).The systematic combination of DGs with energy storage system forms a microgrid(MG),which can operate in islanded mode or grid-connected mode.The intermittent nature of RES and varying load pose substantial obstacles such as voltage and frequency instability,and the unreliability of RES.Unequal feeder impedances and non-linear loads are considered as present challenges in MG control.Hierarchical control has been useful in undertaking solutions to these issues.This paper covers the deep insight of different control methods applied at the primary and secondary control levels in hierarchical control.In primary control,the classification based on droop and non-droop controls is discussed.The virtual synchronization machine(VSM)based control method is reviewed.Voltage and frequency restoration control and economical operations at decentralized and centralized secondary control are analyzed in detail.Based on the existing literature,critical discussion on MG control and future trends are also presented to provide future research perspectives. | Kafeel Ahmed Mehdi Seyedmahmoudian Saad Mekhilef N.M.Mubarak Alex Stojcevski | 2021 | Journal of Modern Power Systems and Clean Energy2021，9，5： | 2 |
| 5 | Education and economic growth in Pakistan: A cointegration and causality analysis显示文摘 | Muhammad Afzal Hafeez Ur Rehman Muhammad Shahid Farooq Kafeel Sarwar | 2011 | International Journal of Educational Research2011，，5： | 1 |
| 6 | Inflammatory pseudotumour of the liver显示文摘 | Kafeel G Telesinghe P U | 1997 | J Clin Pathol1997，50，4： | 1 |
| 7 | Education and economic growth in Pakistan: A cointegration and causality analysis显示文摘 | Mnhammad Afza/ Hafeez Ur Rehman Muhammad Shahid Farooq Kafeel Sarwar | 2011 | International Journal of Educational Research2011，，50： | 1 |
| 8 | Assessment of molybdenum status in soil and forage for ruminant production under semiarid environmental conditions in Sargodha,Pakistan显示文摘 | Zafar Iqbal Khan Kafeel Ahmad | 2010 | Biological Trace Element Reserch2010，8，24： | 1 |
| 9 | Antifungal, phytotoxic and hemagglutination activity of methanolic extracts of Ocimum basilicum显示文摘OBJECTIVE: To report some of the pharmacological features of the medicinal plant Ocimum basilicum.METHODS: In the current studies, Antifungal activity of crude methanolic fraction of Ocimum basilicum was determined against eight pathogenic fungal strains using tube dilution assay. The methanolic fraction was also investigated for phytotoxic and hemagglutination activity.RESULTS: Of the eight strains investigated only Candida albicans and Curvilaria lunata were found to be least affected by plant extract while the rest were significantly inhibited. Moderate phytotoxic activity was observed against lemna minor. Hemagglutination activity showed absence of phytolectins and hence no agglutination of erythrocytes.CONCLUSION: The crude extract of Ocimum basilicum has significant properties against fungi and phytotoxic substances. | Kafeel Ahmad Ali talha Khalil Yusra Ramla Somayya | 2016 | Journal of Traditional Chinese Medicine2016，36，6： | 0 |
| 10 | Evaluation of antileishmanial,antibacterial and brine shrimp cytotoxic potential of crude methanolic extract of Herb Ocimum basilicum(Lamiacea)显示文摘OBJECTIVE:To collect and screen for ethnopharmacological properties(antileishmanial,antibacterial and brine lethality assays) of medicinal plant Ocimum basilicum from Peshawar region(34.008 latitude and 71.57 altitudes).METHODS:In the present study a general antileishmanial activity against Leishmania tropica strain was carried out.The antibacterial potential of the plant was performed against 06 gram positive and 06 gram negative bacteria.Brine shrimp cytotoxicity assay at different concentrations were investigated.RESULTS:The anti-promastigotes profile of the plant showed good antileishmanial activity exhibited LC_(50) value 21.67 μg/mL.The result for gram positive antibacterial activity revealed that the O.basilicum leaves extract possesses significant inhibitory activity at highest two concentrations ranging from20.66 ± 0.31 to 31.86 ± 0.80 for Clostridium perfringens type C and Bacillus subtitilis,respectively,as compared to the gentamycin(27.36 ± 0.55 and21.80 ± 0.72,respectively).For gram negative bacteria good activity was observed.A highest zone of inhibition was recorded for Pseudomonas aeroginosa(28.83 ± 0.28) atthe highest concentration(10 mg/mL).The LC_(50) value obtained for brine shrimp lethality assay was 91.56 μg/mL.CONCLUSION:The herb basil possesses effective cidal activities which make this plant a good candidate for the isolation of antiprotozoal and antibacterial compounds which may lead to the development of novel drug. | Imran Khan Kafeel Ahmad Ali Talha Khalil Jangrez Khan Yusra Ali Khan Muhammad Shahab Saqib Muhammad Naveed Umar Hilal Ahmad | 2015 | Journal of Traditional Chinese Medicine2015，35，3： | 0 |
| 11 | Antimicrobial,hemagglutination and phytotoxic activity of crude ethanolic and aqueous extracts of Seriphidium kurramense显示文摘OBJECTIVE: To investigate the antimicrobial activity, hemagglutination and phytotoxic activity of crude ethanolic and aqueous extracts of Seriphidium kurramense.METHODS: The extracts were analyzed by agar well diffusion assays against five bacterial species:Staphylococcus aureus(S. aureus), methicillin-resistant S. aureus, Escherichia coli, Klebsiella pneumoniae, Bacillus subtilis, and Salmonella typhi. The extracts were also screened against six fungal species — Aspergillus niger, Aspergillus flavus, Alternaria solani, Rhizoctonia solani, Fusarium solani and Pleurotus florida — using the agar tube diffusion method. Additionally, hemagglutination and phytotoxic activities of the crude ethanolic and aqueous extracts were assessed.RESULTS: The crude ethanolic and aqueous extracts showed dose-dependent inhibition of the various tested fungal and bacterial strains. No hemagglutination activity was observed. Both the ethanolic and aqueous extracts showed dose-dependent phytotoxic activity toward Lemna minor.CONCLUSION: The crude ethanolic and aqueous extracts of Seriphidium kurramense possess good antimicrobial and phytotoxic activities, but no hemagglutination activity. | Kafeel Ahmad Amjad Ali Waqar Ahmed Afridi Ramla Somayya Muhammad Jawad Ullah | 2018 | Journal of Traditional Chinese Medicine2018，38，3： | 0 |
| 12 | Isolation of DNA from Saliva and Cheek Cells Using Household Chemicals显示文摘Saliva is a feasible specimen used in sample collection for research purposes.It is reported that saliva typically contains^430,000 epithelial cells per mL.There are various cost-effective methods and commercial kits available which are used to extract DNA from saliva.However,this study aims to explore a simple,time-saving and cheap method of DNA extraction using daily life household chemicals without the help of any electronic equipment.This protocol utilizes pineapple juice which contains bromelain enzyme as a proteolytic agent and dishwashing liquid as a detergent to rupture the cell membrane and remove the contamination.It takes approximately 10-15 min for the completion of extraction procedure.Results have indicated the good quality of DNA by gel electrophoresis and good yield with purity of 1.7-1.8 optical density.Thus,this method serves as a simple,convenient,easy-to-handle,time-saving,cheap and less laborious way for the extraction of DNA in daily routine practices with a good precision of quality and quantity that could be used for diagnostic purposes. | Sanober Kafeel | 2020 | Journal of Life Sciences2020，14，1： | 0 |
| 13 | Phytochemical screening, antioxidant and antibacterial properties of daphne mucronata显示文摘OBJECTIVE:To aim at preliminary phytochemical screening of Daphne mucronata and evaluate its antioxidant and antibacterial activities.METHODS:Preliminary phytochemical screening was conducted for the crude extracts using standard methods.Antioxidant properties of crude methanolic extracts,n-hexane,chloroform,ethyl acetate and aqueous fractions of leaves,roots and bark were evaluated following standard procedures.The antibacterial activities were checked against Acinetobacter baumannii(A.baumannii),Escherichia coli(E.coli),Pseudomonas aeruginosa(P.aeruginosa),Staphylococcus aureus(S.aureus),Morganella morganii(M.morganii)and vancomycin resistant S.aureus(VRSA).RESULTS:Carbohydrates,saponins,steroids,phenols/tannins,flavonoids and glycosides were present in different parts of Daphne mucronata.The extracts showed good antioxidant activity with EC50 values of 157.82-361.61μg/m L.Methanolic extracts of roots showed good activity against A.baumannii(86.95%),E.coli(85.18%)and S.aureus(84.61%).Methanolic extracts of bark were active against A.bumanni(65.21%),M.morganii(65.21%)and E.coli(62.96%).Methanolic extracts of leaves showed good activity against A.bumanni(78.26%),E.coli(77.78%),P.aeruginosa(74.07%),S.aureus(73.07%),M.morganii(69.56%),VRSA(68%)and Proteus vulgaris(60%).The n-hexane fraction of roots was effective against A.bumanni(78.26%).Chlorofom fraction of roots showed moderate activity against A.bumanni(60.86%)and S.aureus(61.53%).Ethyl acetate fraction of roots showed moderate activity against A.bumanii(69.56%),E.coli(62.96%)and S.aureus(69.23%).CONCLUSION:This study illustrates that Daphne mucronata possesses good antioxidant and antibacterial properties.The plant could be further exploited as potential natural antioxidant and as a new source of antimicrobials for treatment of various infections. | Ghosia Lutfullah Asma Shah Kafeel Ahmad Jamila Haider | 2019 | Journal of Traditional Chinese Medicine2019，39，6： | 0 |
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