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| 1 | 团队型文化对赛汝(SERU)生产及运营绩效的影响:中国制造业的实证分析显示文摘SERU生产是以人为中心的、基于社会-技术实践交互作用的复杂生产系统.适配的组织文化可以为SERU生产的成功实施提供重要支持.本文构建了团队型文化、SERU生产与企业运营绩效之间关系的概念模型,并探讨了环境不确定性的调节效应.基于357份来自中国制造企业的调研数据进行实证检验,研究发现团队型文化对SERU生产有显著正向影响,是SERU生产实施的重要前因.环境不确定性对团队型文化与SERU生产之间的关系,以及SERU生产与运营绩效之间的关系有显著调节效应.特别地,环境不确定性强化了团队型文化与SERU生产的多能工运用的关系,以及多能工运用与运营绩效之间的关系.这些结论不仅丰富了SERU生产理论,也为企业实施SERU生产提供了理论指导. | 刘畅 李珍 殷勇 Ikou KAKU | 2021 | 系统工程理论与实践2021，41，2： | 8 |
| 2 | 采用神经网络与模糊控制的制动需求识别显示文摘以保证车辆的制动安全性为最终目的,基于制动推杆行程传感器信号,利用神经网络算法与模糊控制算法提出了对制动需求进行识别的方法。首先采用神经网络算法与模糊控制算法完成对驾驶员制动需求的初步判断,然后通过主缸压力反馈信号对制动系统的制动动作完成程度进行预测,进而对制动需求识别结果进行持续反馈跟踪修正,以保证车辆的制动系统能够实现预期的制动效能。通过MATLAB/Simulink仿真试验与台架试验对控制算法进行了对比与验证,结果表明该方法能迅速准确地识别驾驶员的制动需求,从而为车辆的制动安全性提供保障。 | 刘晏宇 喻凡 宋娟娟 庞纪苏 KAKU Chuyo 郭中陽 | 2020 | 中国机械工程2020，31，23： | 7 |
| 3 | 云南省水稻白叶枯病菌致病力差异的地理分布显示文摘使用12个分别持有不同抗病基因(Xa1,Xa2,Xa3,Xa4,Xa5,Xa7,Xa8,Xa10,Xa11,Xa13,Xa14和Xa21)的近等基因系水稻白叶枯病鉴别品种及3个对照品种(IR24,Toyonishiki和Sigadagabo),鉴别了从云南省收集的138个菌株。结果根据致病谱可以将这些菌株分成A~J共10组。A组菌株仅对Toyonishiki和Sigadagabo两个对照品种致病,J组菌株则能对9个鉴别品种和3个对照品种致病。对不同海拔采集的菌株进行致病力分析的结果表明,从大理、武定等较高海拔粳稻种植区采集的菌株致病力较弱,在鉴别品种上病斑的平均长度不到50mm;而元江、景洪、潞西等低海拔杂交稻种植区采集的菌株致病力较强,在鉴别品种上的病斑平均长度超过100mm。从高海拔稻区到低海拔稻区,病菌致病力有逐步增强的趋势。 | 李成云 TAKAHITO Noda HIROKAZU Ochiai KAZUO Ise HISATOSHI Kaku | 2002 | 西南农业学报2002，15，4： | 7 |
| 4 | The increase in surface CXCR4 expression on lung extravascular neutrophils and its effects on neutrophils during endotoxin-induced lung injury显示文摘Inflammatory stimuli,such as a microbes or lipopolysaccharides,induce a rapid release of neutrophils from the bone marrow and promote neutrophil migration into inflamed sites to promote host defense.However,an excess accumulation and retention of neutrophils in inflamed tissue can cause severe tissue injuries in the later stages of inflammation.Recent studies have reported that both CXCL12 levels in injured lungs and its receptor,CXCR4,on accumulated neutrophils in injured lungs,increased;furthermore,these studies showed that the CXCL12/CXCR4 signaling pathway participated in neutrophil accumulation in the later stages of lipopolysaccharide(LPS)-induced lung injury.However,the mechanisms underlying this increase in surface CXCR4 expression in neutrophils remain unclear.In this study,we found that surface CXCR4 expression increased in extravascular,but not intravascular,neutrophils in the lungs of LPS-induced lung injury model mice.Furthermore,ex vivo studies revealed that CXCL12 acted not only as a chemoattractant,but also as a suppressor of cell death for the lung neutrophils expressing CXCR4.Sulfatide,one of the native ligands for L-selectin,induced the increase of surface CXCR4 expression on isolated circulating neutrophils,suggesting that the activation of L-selectin may be involved in the increase in surface CXCR4.Our findings show that surface CXCR4 levels on neutrophils increase after extravasation into injured lungs,possibly through the activation of L-selectin.The CXCL12/CXCR4 signaling pathway plays an important role in the modulation of neutrophil activity during acute lung injury,not only by promoting chemotaxis but also by suppressing cell death. | Mitsuhiro Yamada Hiroshi Kubo Seiichi Kobayashi Kota Ishizawa Mei He Takaya Suzuki Naoya Fujino Hiroyuki Kunishima Masamitsu Hatta Katsushi Nishimaki Tetsuji Aoyagi Kouichi Tokuda Miho Kitagawa Hisakazu Yano Hirokazu Tamamura Nobutaka Fujii Mitsuo Kaku | 2011 | Cellular & Molecular Immunology2011，8，4： | 6 |
| 5 | 以提高生产率的流水线转单元的变邻域搜索显示文摘为了探索通过流水线向单元转换的方式来提高生产效率的有效方法,研究了在不增加劳动时间的前提下,通过流水线向单元转化来提高生产效率,即降低产品的流通时间。为了降低流水线向单元转化的多目标模型复杂度,提出了将劳动时间作为约束条件而只考虑最小化产品流通时间的单目标模型。鉴于流水线向单元转化是一个NP-hard问题,针对模型的特点,提出了基于变邻域搜索的算法。通过大量的计算实例,验证了流水线向单元转化可以在不增加劳动时间的前提下有效地提高生产效率,并依据实验结果给出了如何进行单元构造以提高生产效率的建议。 | 孙薇 于洋 唐加福 殷勇 Kaku Ikou | 2014 | 计算机集成制造系统2014，20，12： | 5 |
| 6 | Xyloglucan for Generating Tensile Stress to Bend Tree Stem显示文摘响应环境变化,被子植物树由形成紧张木头把他们的茎弄弯,它由充满纤维素的 G 组成(凝胶状) 在纤维房间的墙中的层并且在第二等的木部产生反常张力的应力。我们生产了转基因的白杨植物 overexpressing 在房间墙中减少每特定的多糖,,的几 endoglycanases 第二等的木部由主要、第二等的墙层组成。当水平地放了时,转基因的白杨 overexpressing xyloglucanase 的茎的基础区域不能独自在木部的紧张方面由于低紧张向上弯曲。在野类型的植物, xyloglucan 在多重 layering 期间在 G 层的内部表面被发现。在 situ xyloglucan endotransglucosylase ( XET ),活动证明整个 xyloglucan 的加入,潜在地因为墙紧缩,在内部表面层 S1 和 S2 开始了并且在整个G层开发被保留,当为墙松开的 xyloglucan heptasaccharide ( XXXG )的加入发生在膨胀地区的主要的墙中时。我们建议 xyloglucan 网络被 XET 增强形成在墙界限之间的一个进一步的连接并且分泌了 xyloglucans 以便承受在纤维素 G 层 microfibrils 以内创造的张力的压力。 | Kei'ichi Baba Yong Woo Park Tomomi Kaku Rumi Kaida Miyuki Takeuchi Masato Yoshida Yoshihiro Hosoo Yasuhisa Ojio Takashi Okuyama Toru Taniguchi Yasunori Ohmiya Teiji Kondo Ziv Shani Oded Shoseyov Tatsuya Awano Satoshi Serada Naoko Norioka Shigemi Norioka Takahisa Hayashi | 2009 | Molecular Plant2009，2，5： | 4 |
| 7 | Real-time color holographic video reconstruction using multiple-graphics processing unit cluster acceleration and three spatial light modulators显示文摘We demonstrate real-time three-dimensional(3D)color video using a color electroholographic system with a cluster of multiple-graphics processing units(multi-GPU)and three spatial light modulators(SLMs)corresponding respectively to red,green,and blue(RGB)-colored reconstructing lights.The multi-GPU cluster has a computer-generated hologram(CGH)display node containing a GPU,for displaying calculated CGHs on SLMs,and four CGH calculation nodes using 12 GPUs.The GPUs in the CGH calculation node generate CGHs corresponding to RGB reconstructing lights in a 3D color video using pipeline processing.Real-time color electroholography was realized for a 3D color object comprising approximately 21,000 points per color. | Shohei Ikawa Naoki Takada Hiromitsu Araki Hiroaki Niwase Hiromi Sannomiya Hirotaka Nakayama Minoru Oikawa Yuichiro Mori Takashi Kakue Tomoyoshi Shimobaba Tomoyoshi Ito | 2020 | Chinese Optics Letters2020，18，1： | 4 |
| 8 | Fractalkine and TGF-β1 levels reflect the severity of chronic pancreatitis in humans显示文摘AIM: To clarify whether serum chemokine and cytokine levels can become useful biological and functional markers to assess the severity of chronic pancreatitis (CP). This study aimed at clarifying whether serum chemokine and cytokine levels can become useful biological and functional markers to assess the severity of CP. METHODS: Serum monocyte chemoattractant protein-1 (MCP-1), transforming growth factor beta-1 (TGF-β1), and soluble type fractalkine (s-fractalkine) concentrations were examined in patients with CP (n = 109) and healthy controls (n = 116). Severity of disease was classified in patients with CP by a staging system. Relationships between stage-specifi c various clinical factors and serum MCP-1, TGF-β1, and s-fractalkine levels were investigated. Furthermore, 57 patients with non-alcoholic CP were similarly evaluated in order to exclude in? uence of alcohol intake. RESULTS: Patients with CP showed signifi cant higher levels of serum TGF-β1 and s-fractalkine, but not MCP-1, compared to the controls. Serum TGF-β1 in the severe stage and s-fractalkine in the mild and thesevere stage of CP significantly increased compared to those of controls. However, it was observed that both TGF-β1 and s-fractalkine levels were affected by alcohol intake. In patients with non-alcoholic CP, serum TGF-β1 showed significant increase in the moderate stage of CP, and serum s-fractalkine revealed signifi cant increase in the early stage of CP. CONCLUSION: It is suggested that the measurement of serum F-fractalkine is useful to diagnose early-stage CP. Moreover, the combined determination of both, s-fractalkine and TGF-β1, in human sera may be helpful in evaluating the severity status of CP. | Mikihiko Yasuda Tetsuhide Ito Takamasa Oono Ken Kawabe Toyoma Kaku Hisato Igarashi Taichi Nakamura Ryoichi Takayanagi | 2008 | World Journal of Gastroenterology2008，14，42： | 4 |
| 9 | Chemoradiotherapy with twice-weekly administration of low-dose gemcitabine for locally advanced pancreatic cancer显示文摘AIM:To evaluate the chemoradiotherapy for locally advanced pancreatic cancer utilizing low dose gemcitabine as a radiation sensitizer administered twice weekly. METHODS: We performed a retrospective analysis of chemoradiotherapy utilizing gemcitabine administered twice weekly at a dose of 40 mg/m2. After that, maintenance systemic chemotherapy with gemcitabine, at a dose of 1000 mg/m2, was administered weekly for 3 wk with 1-wk rest until disease progression or unacceptable toxicity developed. RESULTS: Eighteen patients with locally advanced unresectable pancreatic cancer were enrolled. Three of those patients could not continue with the therapy; one patient had interstitial pneumonia during radiation therapy and two other patients showed liver metastasis or peritoneal metastasis during an early stage of the therapy. The median survival was 15.0 mo and the overall 1-year survival rate was 60%, while the median progression-free survival was 8.0 mo. The subgroup which showed the reduction of tumor development, more than 50% showed a tendency for a better prognosis; however, other parameters including age, gender and performance status did not correlate with survival. The median survival of the groups that died of liver metastasis and peritoneal metastasis were 13.0 mo and 27.7 mo, respectively.CONCLUSION: Chemoradiotherapy with low-dose gemcitabine administered twice weekly could be effective to patients with locally advanced pancreatic cancer; however, patients developing liver metastases had a worse prognosis. Another chemoradiotherapy strategy might be needed for those patients, such as administrating one or two cycles of chemotherapy initially, followed by chemoradiotherapy for the cases with no distant metastases. | Hisato Igarashi Tetsuhide Ito Ken Kawabe Terumasa Hisano Yoshiyuki Arita Toyoma Kaku Ryoichi Takayanagi | 2008 | World Journal of Gastroenterology2008，14，34： | 3 |
| 10 | 具有“普通型”和“胃型”两种形态特征的子宫颈腺癌:临床病理特征、免疫组化及高危型HPV状态分析显示文摘WHO(第四版)子宫肿瘤分类将子宫颈腺癌(ECA)分为“普通型”和“胃型”。由于两型ECA具有不同的免疫表型、HPV状态及预后,因此被认为具有不同的组织学起源。 | Wada T Ohishi Y Kaku T 康锶鹏 余英豪 | 2017 | 临床与实验病理学杂志2017，33，9： | 3 |
| 11 | Three-dimensional computed tomography combined with hysterosalpingography is useful for both diagnosis and treatment of iatrogenic diverticulum of the uterus显示文摘 | Yoshihiko Shimizu Hitoshi Kitahara Wakasa Yamaguchi Shoji Kaku Nobuyuki Kita Takashi Murakami | 2010 | Fertility and Sterility2010，，3： | 2 |
| 12 | Distribution and relative activity of matrix metalloproteinase-2 in human coronal dentin显示文摘The presence of matrix metalloproteinase-2 (MMP-2) in dentin has been reported, but its distribution and activity level in mature human coronal dentin are not well understood. The purpose of this study was to determine the MMP-2 distribution and relative activity in demineralized dentin. Crowns of twenty eight human molars were sectioned into inner (ID), middle (MD), and outer dentin (OD) regions and demineralized. MMP-2 was extracted with 0.33 mol·L -1 EDTA/2 mol·L -1 guanidine-HCl, pH 7.4, and MMP-2 concentration was estimated with enzyme-linked immunoabsorbant assay (ELISA). Further characterization was accomplished by Western blotting analysis and gelatin zymography. The mean concentrations of MMP-2 per mg dentin protein in the dentin regions were significantly different (P=0.043): 0.9 ng (ID), 0.4 ng (MD), and 2.2 ng (OD), respectively. The pattern of MMP-2 concentration was OD>ID>MD. Western blotting analysis detected ~66 and ~72 kDa immunopositive proteins corresponding to pro-and mature MMP-2, respectively, in the ID and MD, and a ~66 kDa protein in the OD. Gelatinolytic activity consistent with MMP-2 was detected in all regions. Interestingly, the pattern of levels of Western blot immunodetection and gelatinolytic activity was MD>ID>OD. The concentration of MMP-2 in human coronal dentin was highest in the region of dentin that contains the dentinoenamel junction and least in the middle region of dentin. However, levels of Western blot immunodetection and gelatinolytic activity did not correlate with the estimated regional concentrations of MMP-2, potentially indicating region specific protein interactions. | Lee W. Boushell Masaru Kaku Yoshiyuki Mochida Mitsuo Yamauchi | 2011 | International Journal of Oral Science2011，3，4： | 2 |
| 13 | Real-time electroholography using a single spatial light modulator and a cluster of graphics-processing units connected by a gigabit Ethernet network显示文摘Systems containing multiple graphics-processing-unit(GPU)clusters are difficult to use for real-time electroholography when using only a single spatial light modulator because the transfer of the computer-generated hologram data between the GPUs is bottlenecked.To overcome this bottleneck,we propose a rapid GPU packing scheme that significantly reduces the volume of the required data transfer.The proposed method uses a multi-GPU cluster system connected with a cost-effective gigabit Ethernet network.In tests,we achieved real-time electroholography of a three-dimensional(3D)video presenting a point-cloud 3D object made up of approximately 200,000 points. | Hiromi Sannomiya Naoki Takada Tomoya Sakaguchi Hirotaka Nakayama Minoru Oikawa Yuichiro Mori Takashi Kakue Tomoyoshi Shimobaba Tomoyoshi Ito | 2020 | Chinese Optics Letters2020，18，2： | 2 |
| 14 | Endoscopic submucosal dissection is superior to conventional endoscopic resection as a curative treatment for early squamous cell carcinoma of the esophagus (with video)显示文摘 | Hiroaki Takahashi Yoshiaki Arimura Hosokawa Masao Satoshi Okahara Tokuma Tanuma Junichi Kodaira Hidetoshi Kagaya Yuichi Shimizu Kaku Hokari Hiroyuki Tsukagoshi Yasuhisa Shinomura Masahiro Fujita | 2010 | Gastrointestinal Endoscopy2010，，2： | 2 |
| 15 | Generalized periodontitis treated with periodontal,orthodontic,and prosthodontic therapy:A case report显示文摘BACKGROUND Generalized periodontitis is a severe periodontal disease characterized by rapid periodontal destruction in healthy persons.This case report describes the treatment of a severe crowding,large overjet,and occlusal collapse due to the loss of anterior guidance with generalized periodontitis.CASE SUMMARY A 35-year-old female patient with a chief complaint of crowding and maxillary protrusion was diagnosed with generalized periodontitis by clinical and radiographic examinations.To improve crowding and overjet,orthodontic treatment was performed after basic periodontal therapy.Severely damaged upper right lateral incisor and left canine were extracted,and lower right first premolar and left second premolar were also removed to treat severe crowding.After orthodontic treatment,periodontal flap surgery for upper left molars and guided tissue regeneration for the lower left second molar was performed.Then,a dental implant was inserted in the upper left canine legion.The esthetics of the maxillary anterior tooth was improved by prosthetic restorations.The treatment result showed a well-improved occlusion with proper anterior guidance and healthy periodontal tissue after a retention period of 10 years.CONCLUSION Periodontal,orthodontic,and prosthodontic treatments are extremely useful to improve function and stable periodontal tissue for generalized periodontitis. | Masato Kaku Shinji Matsuda Takayasu Kubo Saiji Shimoe Kazuhiro Tsuga Hidemi Kurihara Kotaro Tanimoto | 2021 | World Journal of Clinical Cases2021，9，21： | 2 |
| 16 | Loosening Xyloglucan Accelerates the Enzymatic Degradation of Cellulose in Wood显示文摘以便创造在纤维素的树,在生物资源的最丰富的部件,能是酶地 hydrolyzed 高度为 bioethanol 的生产,我们从几棵转基因的白杨,每 overexpressing 任何一个 xyloglucanase,绗维素酶, xylanase,或 galactanase 检验了木部的 saccharification。绗维素酶准备完成的纤维素降级的水平比在野类型的植物的木部在木部 overexpressing xyloglucanase 和在木部 overexpressing xylanase 和绗维素酶更大的大部分是显著地更大的。尽管降级的高度根本发生在所有木部 loci,纤维素 microfibrils 的水晶的区域高度在木部 overexpressing xyloglucanase 被降级。因为在 microfibrils 和 xyloglucans 之间的建筑群能是对纤维素降级特别地抵抗的一个区域,松开 xyloglucan 能在木头便于纤维素的酶的水解作用。 | Rumi Kaida Tomomi Kaku Kei'ichi Baba Masafumi Oyadomari Takashi Watanabe Koji Nishida Toshiji Kanaya Ziv Shani Oded Shoseyov Takahisa Hayashi | 2009 | Molecular Plant2009，2，5： | 2 |
| 17 | Renal involvement in Henoch-Schonlein purpura:a multivariate analysis of prognostic factors显示文摘 | Kaku Y Nohara K Honda S | 1998 | Kidney Int1998，53，6： | 1 |
| 18 | Endometrial carcinoma associated with hyperplasia显示文摘 | Kaku T Yoshikawa H Tsuda H | 1996 | Oynecol Oncol1996，60，： | 1 |
| 19 | Clinico-cytological study of uterine papillary serous carcinoma显示文摘 | Hagiwara T Kaku T Kobayashi H | 2005 | Cytopatholology2005，16，3： | 1 |
| 20 | Effects of vascular endothelial growth factor on osteoclast induction during tooth movement in mice显示文摘 | Kaku M Kohno S Kawata T | 2001 | J Dent Res2001，80，： | 1 |
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