|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | How tubular epithelial cells dictate the rate of renal fibrogenesis?显示文摘The main threat to a kidney injury,whatever its cause and regardless of whether it is acute or chronic,is the initiation of a process of renal fibrogenesis,since fibrosis can auto-perpetuate and is of high prognostic significance in individual patients.In the clinic,a decrease in glomerular filtration rate correlates better with tubulointerstitial damage than with glomerular injury.Accumulation of the extracellular matrix should not be isolated from other significant cellular changes occurring in the kidney,such as infiltration by inflammatory cells,proliferation of myofibroblasts,obliteration of peritubular capillaries and atrophy of tubules.The aim of this review is to focus on tubular epithelial cells(TEC),which,necessarily involved in the repair process,eventually contribute to accelerating fibrogenesis.In the context of injury,TEC rapidly exhibit phenotypic and functional changes that recall their mesenchymal origin,and produce several growth factors known to activate myofibroblasts.Because they are high-demanding energy cells,TEC will subsequently suffer from the local hypoxia that progressively arises in a microenvironment where the matrix increases and capillaries become rarified.The combination of hypoxia and metabolic acidosis may induce a vicious cycle of sustained inflammation,at the center of which TEC dictate the rate of renal fibrogenesis. | Kevin Louis Alexandre Hertig | 2015 | World Journal of Nephrology2015，4，3： | 16 |
| 2 | Gastrointestinal sarcoidosis associated with pneumatosis cystoides intestinalis显示文摘A 39-year-old male reported fevers,weight loss,watery loose stools,and decreased visual acuity in his right eye over the prior five years.He was pancytopenic,had an elevated American council on exercise level,total bilirubin,and alkaline phosphatase.Computed tomography revealed massive hepatosplenomegaly and emphysematous lung changes.Liver biopsy showed non caseating granulomas.The patient was diagnosed with extrapulmonary sarcoidosis and was treated with prednisone.The patient symptomatically improved but 5 mo later presented with abdominal pain caused by perforation of the cecum.He underwent a cecectomy and pathology revealed pneumatosis cystoides intestinalis.This represents the first reported association between pneumatosis cystoides intestinalis and sarcoidosis.The etiology of pneumatosis cystoides intestinalis in this case was likely multifactorial and involved both effects of the corticosteroids as well as the advanced nature of the gastrointestinal sarcoidosis.Furthermore this case has the unique features of emphysematous lung changes and pancytopenia which are uncommon with sarcoidosis. | Hussein Rahim Mubashir Khan Jay Hudgins Kevin Lee Lei Du Louis Amorosa | 2013 | World Journal of Gastroenterology2013，19，7： | 3 |
| 3 | Utility of Biomarkers in Prediction of Response to Ablative Therapy in Barrett’s Esophagus显示文摘 | Ganapathy A. Prasad Kenneth K. Wang Kevin C. Halling Navtej S. Buttar Louis–Michel Wongkeesong Alan R. Zinsmeister Shannon M. Brankley Emily G. Barr Fritcher Wytske M. Westra Kausilia K. Krishnadath Lori S. Lutzke Lynn S. Borkenhagen | 2008 | Gastroenterology2008，，： | 2 |
| 4 | Addressing vulnerability,building resilience:community-based adaptation to vectorborne diseases in the context of global change显示文摘Background:The threat of a rapidly changing planet-of coupled social,environmental and climatic change-pose new conceptual and practical challenges in responding to vector-borne diseases.These include non-linear and uncertain spatial-temporal change dynamics associated with climate,animals,land,water,food,settlement,conflict,ecology and human socio-cultural,economic and political-institutional systems.To date,research efforts have been dominated by disease modeling,which has provided limited practical advice to policymakers and practitioners in developing policies and programmes on the ground.Main body:In this paper,we provide an alternative biosocial perspective grounded in social science insights,drawing upon concepts of vulnerability,resilience,participation and community-based adaptation.Our analysis was informed by a realist review(provided in the Additional file 2)focused on seven major climate-sensitive vectorborne diseases:malaria,schistosomiasis,dengue,leishmaniasis,sleeping sickness,chagas disease,and rift valley fever.Here,we situate our analysis of existing community-based interventions within the context of global change processes and the wider social science literature.We identify and discuss best practices and conceptual principles that should guide future community-based efforts to mitigate human vulnerability to vector-borne diseases.We argue that more focused attention and investments are needed in meaningful public participation,appropriate technologies,the strengthening of health systems,sustainable development,wider institutional changes and attention to the social determinants of health,including the drivers of co-infection.Conclusion:In order to respond effectively to uncertain future scenarios for vector-borne disease in a changing world,more attention needs to be given to building resilient and equitable systems in the present. | Kevin Louis Bardosh Sadie JRyan Kris Ebi Susan Welburn Burton Singer | 2017 | Infectious Diseases of Poverty2017，6，1： | 1 |
| 5 | The influence of national culture on the formation of technology alliances by entrepreneurial firms显示文摘 | Steensma H Kevin Louis Marino Mark Weaver K | 2000 | Academy of Management Journal2000，43，5： | 1 |
| 6 | Effect of Age on Treatment Outcomes in C lostridium difficile Infection显示文摘 | Thomas J. Louie Mark A. Miller Derrick W. Crook Arnold Lentnek Louis Bernard Kevin P. High Youe‐Kong Shue Sherwood L. Gorbach | 2013 | J Am Geriatr Soc2013，，： | 1 |
| 7 | The influence of national culture on the formation of technology alliance by entrepreurial firms 显示文摘 | STEENSMA H KEVIN LOUIS MARINO MARK WEAVERK ETAL | 2000 | Academy of Management Journal2000，43，5： | 1 |
| 8 | Vertebral Artery Ostium Atherosclerotic Plaque as a Potential Source of Posterior Circulation Ischemic Stroke: Result From Borgess Medical Center Vertebral Artery Ostium Stenting Registry显示文摘 | Firas Al-Ali Tom Barrow Li Duan Anne Jefferson Susan Louis Kim Luke Kevin Major Sandy Smoker Sarah Walker Margaret Yacobozzi | 2011 | Stroke2011，，9： | 1 |
| 9 | Correlation of histology with biomarker status after photodynamic therapy in Barrett esophagus显示文摘 | Ganapathy A.Prasad Kenneth K.Wang Kevin C.Halling Navtej S.Buttar Louis‐MichelWongkeesong Alan R.Zinsmeister Shannon M.Brankley Wytske M.Westra Lori S.Lutzke Lynn S.Borkenhagen KellyDunagan | 2008 | Cancer2008，，3： | 1 |
| 10 | Consenso Latinoamericano de Estre?imiento Crónico显示文摘 | Max Schmulson Wasserman Carlos Francisconi Kevin Olden Luis Aguilar Paíz Luis Bustos-Fernández Henry Cohen Maria do Carmo Passos Marina Alejandra González-Martínez Beatriz Iade Guido Iantorno Carlos Ledesma Ginatta Aurelio López-Colombo Cesar Louis Pérez | 2008 | Gastroenterologia y Hepatologia2008，，2： | 1 |
| 11 | Biological invasions in soil: DNA barcoding as a monitoring tool in a multiple taxa survey targeting European earthworms and springtails in North America显示文摘 | David Porco Thibaud Deca?ns Louis Deharveng Samuel W. James Dariusz Skar?yński Christer Erséus Kevin R. Butt Benoit Richard Paul D. N. Hebert | 2013 | Biological Invasions2013，，4： | 1 |
| 12 | The Influence of National Culture on the Formation of Technology Alliance by Entrepreurial Firms 显示文摘 | Steensma H Kevin Louis Marino Mark Weaverk | 2000 | Academy of Management Journal2000，43，5： | 1 |
| 13 | Anterior Cruciate Ligament Injury Versus Tibial Spine Fracture in the Skeletally Immature Knee: A Comparison of Skeletal Maturation and Notch Width Index显示文摘 | Mininder S. Kocher Rahul Mandiga Kevin Klingele Louis Bley Lyle J. Micheli | 2004 | Journal of Pediatric Orthopaedics2004，，： | 1 |
| 14 | Platelet Expression Profiling and Clinical Validation of Myeloid-Related Protein-14 as a Novel Determinant of Cardiovascular Events显示文摘 | Aileen M. Healy Michael D. Pickard Aruna D. Pradhan Yunmei Wang Zhiping Chen Kevin Croce Masashi Sakuma Can Shi Alexandre C. Zago Joseph Garasic Andrew I. Damokosh Tracy L. Dowie Louis Poisson James Lillie Peter Libby Paul M. Ridker Daniel I. Simon | 2006 | Circulation2006，，19： | 1 |
| 15 | Molecular cloning of a human gene that is a member Of the nerve growth factor family 显示文摘 | KEVIN R J LOUIS F R | 1990 | Proe Natl Acad Sci USA1990，，87： | 1 |
| 16 | Prophylaxis of postoperative endophthalmitis after cataract surgery显示文摘 | David F. Chang Rosa Braga-Mele Nick Mamalis Samuel Masket Kevin M. Miller Louis D. Nichamin Richard B. Packard Mark Packer | 2007 | Journal of Cataract & Refractive Surgery2007，，10： | 1 |
| 17 | RFID的未来之路大有希望——众多美国专家谈RFID显示文摘根据有关的市场预测报告,RFID(无线射频识别)的未来之路是大有希望的。据IDTechEx公司提供的最新报告估计:2006年,RFID标签的销售量几乎将达到自其被发明以来60年内的总销售量的三倍之多;全球RFID市场额到2008年将达到70亿美元。这主要是因为单个产品级别RFID的发展速度比人们预想的要快得多,另外它们比货盘或包装箱级别的RFID标签所面临的挑战也要少。 | 本刊编辑部 Kevin Ashton Erik Michielsen Rafael Moreno Shahram Moradpour Chantal Polsonetti Thomas Ryan Louis Sirico | 2006 | 金卡工程2006，10，4： | 0 |
| 18 | The Global Soil Mycobiome consortium dataset for boosting fungal diversity research显示文摘Fungi are highly important biotic components of terrestrial ecosystems,but we still have a very limited understanding about their diversity and distribution.This data article releases a global soil fungal dataset of the Global Soil Mycobiome consortium(GSMc)to boost further research in fungal diversity,biogeography and macroecology.The dataset comprises 722,682 fungal operational taxonomic units(OTUs)derived from PacBio sequencing of full-length ITS and 18S-V9 variable regions from 3200 plots in 108 countries on all continents.The plots are supplied with geographical and edaphic metadata.The OTUs are taxonomically and functionally assigned to guilds and other functional groups.The entire dataset has been corrected by excluding chimeras,index-switch artefacts and potential contamination.The dataset is more inclusive in terms of geographical breadth and phylogenetic diversity of fungi than previously published data.The GSMc dataset is available over the PlutoF repository. | Leho Tedersoo Vladimir Mikryukov Sten Anslan Mohammad Bahram Abdul Nasir Khalid Adriana Corrales Ahto Agan Aída-M.Vasco-Palacios Alessandro Saitta Alexandre Antonelli Andrea C.Rinaldi Annemieke Verbeken Bobby P.Sulistyo Boris Tamgnoue Brendan Furneaux Camila Duarte Ritter Casper Nyamukondiwa Cathy Sharp César Marín D.Q.Dai Daniyal Gohar Dipon Sharmah Elisabeth Machteld Biersma Erin K.Cameron Eske De Crop Eveli Otsing Evgeny A.Davydov Felipe E.Albornoz Francis Q.Brearley Franz Buegger Genevieve Gates Geoffrey Zahn Gregory Bonito Indrek Hiiesalu Inga Hiiesalu Irma Zettur Isabel C.Barrio Jaan Pärn Jacob Heilmann-Clausen Jelena Ankuda John Y.Kupagme Joosep Sarapuu Jose G.Maciá-Vicente Joseph Djeugap Fovo József Geml Juha M.Alatalo Julieta Alvarez-Manjarrez Jutamart Monkai Kadri Põldmaa Kadri Runnel Kalev Adamson Kari A.Bråthen Karin Pritsch Kassim I.Tchan Kęstutis Armolaitis Kevin D.Hyde Kevin K.Newsham Kristel Panksep Lateef A.Adebola Louis J.Lamit Malka Saba Marcela Eda Silva Cáceres Maria Tuomi Marieka Gryzenhout Marijn Bauters Miklós Bálint Nalin Wijayawardene Niloufar Hagh-Doust Nourou S.Yorou Olavi Kurina Peter E.Mortimer Peter Meidl RHenrik Nilsson Rasmus Puusepp Rebeca Casique-Valdés Rein Drenkhan Roberto Garibay-Orijel Roberto Godoy Saleh Alfarraj Saleh Rahimlou Sergei Põlme Sergey V.Dudov Sunil Mundra Talaat Ahmed Tarquin Netherway Terry W.Henkel Tomas Roslin Vladimir E.Fedosov Vladimir G.Onipchenko WAErandi Yasanthika Young Woon Lim Meike Piepenbring Darta Klavina Urmas Kõljalg Kessy Abarenkov | 2021 | Fungal Diversity2021，，6： | 0 |
| 19 | Correction to:Addressing vulnerability,building resilience:community-based adaptation to vector-borne diseases in the context of global change显示文摘Correction After publication of this article[1]it came to our attention that the name of the author Sadie Ryan was incorrectly shown.Her correct name is Sadie J.Ryan.The original article has been updated to reflect this change. | Kevin Louis Bardosh Sadie JRyan Kris Ebi Susan Welburn Burton Singer | 2018 | Infectious Diseases of Poverty2018，7，1： | 0 |
| 20 | On dogs, people, and a rabies epidemic: results from a sociocultural study in Bali, Indonesia显示文摘Background:Previously free of rabies,Bali experienced an outbreak in 2008,which has since caused a large number of human fatalities.In response,both mass dog culling and vaccination have been implemented.In order to assess potential community-driven interventions for optimizing rabies control,we conducted a study exploring the relationship between dogs,rabies,and the Balinese community.The objectives of this study were to:i)understand the human-dog relationship in Bali;ii)explore local knowledge,attitudes,and practices(KAPs)relating to rabies;and iii)assess potential community-driven activities to optimize rabies control and surveillance.Methods:Conducted between February and June 2011,the study combined a questionnaire(n=300;CI=95%;error margin=5%)and focus group discussions(FGDs)in 10 villages in the Denpasar,Gianyar,and Karangasem regencies.The questionnaire included a Likert scale to assess community knowledge and attitudes.For the knowledge assessment,three points were given for a correct answer,while wrong answers and uncertain answers were given zero points.For the attitudes assessment,three points were given for a positive answer,two points for a neutral answer,and one point for a negative answer.Respondent knowledge was categorized as good(score>40),fair(score 20–40),or poor(score<20),based on a maximum total score 60.Respondent attitudes were categorized as positive(score>26),neutral(score 13–26),or negative(score<13),based on a maximum total score of 39.Mixed-gender FGDs in each sub-village(banjar)were conducted,each involving 7–15 participants to complement the questionnaire results.On a follow-up research trip in mid-2013,the data analysis was triangulated and validated using semi-structured interviews.Questionnaire data were analyzed descriptively using SPSS 17.0,while qualitative data from interviews and FGDs were analyzed manually according to accepted methods of coding and memo writing.The chi-square test was then used to analyze the statistical relationships between knowledge and attitudes of the respondents.Results:Out of the total 300 respondents,most were predominantly male(82%),Hindu(99%),married(96%),older than 30 years of age(92%),and owned dogs(72%6).Dog ownership was motivated by culture,personal taste,and function,with dogs was being used as guards(85%)and companion animals(27%),and was sometimes related to religious or traditional obligations(2%).Relating to their culture and local beliefs,and eventually becoming their way of life,79%of respondents kept free-roaming dogs.with the rabies outbreak in Bali and Westerm breeds becoming more popular,more responsible dog ownership(leashing,confining,regular feeding)became more acceptable and changed community perceptions on keeping dogs,even though the sustainability of this practice cannot be gauged.In addition,the economic situation posed major problems in rural areas.The level of community knowledge about rabies and its associated control programs were generally fair and community attitudes were positive.However,community KAPs still need to be improved.A total of 74%respondents reported to have vaccinated their dogs in 2011,but only few were found to report rabid animals to livestock officers(12%)and a significant number believed that washing a bite wound was not important(62%).Moreover,free-roaming dog practices and discarding of unwanted female puppies still continue and possibly create difficulties for rabies elimination as these practices potentially increase the stray dog population.We identified three major sociocultural aspects with potential for community-driven interventions to optimize current rabies elimination efforts:integrating local notions of ahimsa(non-violence)into education campaigns,engaging communities through the local banjar sociopolitical system,and working with traditional legal structures to increase local compliance with rabies control.Conclusion:The human-dog relationship in Bali is multifaceted.Due to the uniqueness of the culture and the local beliefs,and encouraged by a socioeconomic aspect,a number of local practices were found to be constituting risk factors for continued rabies spread.Community knowledge and attitudes,which can consequently result in behavioral changes,needs to be improved across different genders,ages educational backgrounds,and roles in the commurnity,regardless of the individual village's experiences with rabies.Furthermore,community-driven activities based on sociocultural conditioning and community capacity at the banjar and village levels,such as public awareness activities,vaccination,dog registration,dog population management,and rapid response to dog bites,were identified as being able to complement the rabies control program in Bali.The program also needs recognition or acknowledgement from governments,especially local govemment as well as regular mentoring to improve and sustain community participation. | Maria Digna Winda Widyastuti Kevin Louis Bardosh Sunar C Basri E Basuno A.Jatikusumah R.A.Arief A.A.G.Putra A.Rukmantara A.T.S.Estoepangestie I.Willyanto I.K.G.Natakesuma I.P.Sumantra D.Grace F.Unger J.Gilbert | 2015 | Infectious Diseases of Poverty2015，4，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员