|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Coordinated peak expression of MMP-26 and TIMP-4 in preinvasive human prostate tumor显示文摘因为早察觉和治疗为病人的医药管理是批评的,为早前列腺癌症诊断的新奇简历标记的鉴定是高度重要的。在基础房间层和地下室膜的连续性的混乱为高级职业人员静电干扰 intraepithelial 瘤形成(HGPIN ) 的前进是必要的到在人的前列腺的侵略腺癌。涉及变换到侵略显型的分子是强烈审查的题目。我们以前报导了矩阵 metalloproteinase-26 (MMP-26 ) 经由地下室膜蛋白质并且由激活 MMP-9 的酶原形式的劈开支持人的前列腺癌症房间的侵略。而且,我们发现了 metalloproteinases-4 (TIMP-4 ) 的那个织物禁止者是大多数有势力 MMP-26 的内长的禁止者。这里,我们更高示威(p<0.0001 ) 在 HGPIN 和癌症的 MMP-26 和 TIMP-4 表示,与非肿瘤的 acini 相比。他们的表示层次在 HGPIN 是最高的,但是在一样的纸巾在侵略癌症(为各个的 p<0.001 ) 衰退。连续前列腺癌症织物节染色的 Immunohistochemical 建议 MMP-26 和 TIMP-4 的 colocalization。现在的学习显示 MMP-26 和 TIMP-4 可以在 HGPIN 的变换期间起一个不可分的作用到侵略癌症并且可以也为早前列腺癌症诊断用作标记。房间研究(2006 ) 16:750-758。做 i:10.1038/sj .cr.7310089;出版联机 2006 年 8 月 29 日。 | Seakwoo Lee Kevin K Desai Kenneth A Iczkowski Robert G Newcomer Kevin J WU Yun-Ge Zhao Winston W Tan Mark D Roycik Qing-Xiang Amy Sang | 2006 | Cell Research2006，16，9： | 18 |
| 2 | The American Heart Association’s Get With the Guidelines(GWTG)-Stroke development and impact on stroke care显示文摘The American Heart Association’s Get With the Guidelines(GWTG)-Stroke programme has changed stroke care delivery in the USA since its establishment in 2003.GWTG is a voluntary registry and continuous quality improvement initiative that collects data on patient characteristics,hospital adherence to guidelines and inpatient outcomes.Implementation of the programme saw increased provision of evidence-based care and improved patient outcomes.This review will describe the development of the programme and discuss the impact on stroke outcomes and transformation of stroke care delivery that followed its implementation. | Cora H Ormseth Kevin N Sheth Jeffrey L Saver Gregg C Fonarow Lee H Schwamm | 2017 | Stroke & Vascular Neurology2017，2，2： | 15 |
| 3 | Calcium signaling and T-type calcium channels in cancer cell cycling显示文摘Regulation of intracellular calcium is an important signaling mechanism for cell proliferation in both normal and cancerous cells. In normal epithelial cells, free calcium concentration is essential for cells to enter and accomplish the S phase and the M phase of the cell cycle. In contrast, cancerous cells can pass these phases of the cell cycle with much lower cytoplasmic free calcium concentrations, indicating an alternative mechanism has developed for fulfilling the intracellular calcium requirement for an increased rate of DNA synthesis and mitosis of fast replicating cancerous cells. The detailed mechanism underlying the altered calcium loading pathway remains unclear; however, there is a growing body of evidence that suggests the T-type Ca2+ channel is abnormally expressed in cancerous cells and that blockade of these channels may reduce cell proliferation in addition to inducing apoptosis. Recent studies also show that the expression of T-type Ca2+ channels in breast cancer cells is proliferation state dependent, i.e. the channels are expressed at higher levels during the fast-replication period, and once the cells are in a non-proliferation state, expression of this channel isminimal. Therefore, selectively blocking calcium entry into cancerous cells may be a valuable approach for preventing tumor growth. Since T-type Ca2+ channels are not expressed in epithelial cells, selective T-type Ca2+ channel blockers may be useful in the treatment of certain types of cancers. | James T Taylor Xiang-Bin Zeng Jonathan E Pottle Kevin Lee Alun R Wang Stephenie G Yi lennifer A S Scruggs Suresh S Sikka Ming Li | 2008 | World Journal of Gastroenterology2008，14，32： | 12 |
| 4 | The interaction between the Wnt/β-catenin signaling cascade and PKG activation in cancer显示文摘The activation of the Wnt/β-catenin signaling cascade has been well studied and documented in colorectal cancer(CRC).The long-term use of non-steroidal anti-inflammatory drugs(NSAIDs) has been shown to reduce the incidence and risk of death from CRC in numerous epidemiological studies.The NSA1 D sulindac has also been reported to cause regression of precancerous adenomas in individuals with familial adenomatous polyposis who are at high risk of developing CRC.The mechanism responsible for cancer chemopreventive activity of NSAIDs is not well understood but may be unrelated to their cyclooxygenase inhibitory activity.Emerging evidence suggests that sulindac inhibits the growth of colon tumor cells by suppressing the activity of certain phosphodiesterase isozymes to activate cGMβ-dependent protein kinase,PKG,through the elevation of the second messenger cyclic guanosine monophosphote,cGMP.PKG activation has been shown to inhibit the nuclear translocation of β-catenin,reduce β-catenin mRNA and protein levels,and suppress the transcriptional activity of β-catenin.This review describes the relationship between the Wnt/β-catenin signaling cascade and the activation of PKG through PDE inhibition and elevation of intracellular cGMP levels. | Kevin Lee Gary A Piazza | 2017 | The Journal of Biomedical Research2017，31，3： | 7 |
| 5 | Interleukin-28B Polymorphism Improves Viral Kinetics and Is the Strongest Pretreatment Predictor of Sustained Virologic Response in Genotype 1 Hepatitis C Virus显示文摘 | Alexander J. Thompson Andrew J. Muir Mark S. Sulkowski Dongliang Ge Jacques Fellay Kevin V. Shianna Thomas Urban Nezam H. Afdhal Ira M. Jacobson Rafael Esteban Fred Poordad Eric J. Lawitz Jonathan McCone Mitchell L. Shiffman Greg W. Galler William M. Lee | 2010 | Gastroenterology2010，，1： | 7 |
| 6 | Tumor Antigen Specific Activation of Primary Human T-Cells Expressing a Virally Encoded Chimeric T-Cell Receptor Specific for p185HER2显示文摘We have developed and tested chimeric T-cell receptors (TCR) specific for p185HER2. In these experiments, retroviral vectors expressing the N29γ or N29ζ receptors were constructed in pRET6. Amphotropic viral producer cells were established in the GALV-based PG13 packaging cell line. Ficoll purified human peripheral blood lymphocytes (PBL) were virally transduced using an optimized protocol incorporating activation with immobilized anti-CD3/anti-CD28 monoclonal anti- bodies, followed by viral infection in the presence of fibronectin fragment CH296. Transduced cells were co-cultured with human tumor cell lines that overexpress (SK-OV-3) or underexpress (MCF7) p185HER2 to assay for antigen specific im- mune responses. Both CM+ and CD8+ T-cells transduced with the N29γ or N29ζ chTCR demonstrated HER2-specific anti- gen responses, as determined by release of Th1 like cytokines, and cellular cytotoxicity assays. Our results support the fea- sibility of adoptive immunotherapy with genetically modified T-cells expressing a chTCR specific for p185HER2. | 杨建民 Michael S FRIEDMAN Christopher M REYNOLDS Marianne T HUBEN Lee WILKE Jennifer FULLER 李桥 Zelig ESHHAR James J MULE Kevin T MCDONAGH | 2004 | Journal of Microbiology and Immunology2004，2，4： | 5 |
| 7 | Impact of time to surgery from injury on postoperative infection and deep vein thrombosis in periprosthetic knee fractures显示文摘Purpose:Periprosthetic fracture (PPF) is a serious complication that occurs in 0.3%-2.5% of all total knee arthroplasties used to treat end-stage arthritis. To our knowledge, there are no studies in the literature that evaluate the association between time to surgery after PPF and early postoperative infections or deep vein thrombosis (DVT). This study tests our hypothesis that delayed time to surgery increases rates of postoperative infection and DVT after PPF surgery.Methods:Our study cohort included patients undergoing PPF surgery in the American College of Surgeons National Surgical Quality Improvement Program database (2006-2015). The patients were dichotomized based on time to surgery: group 1 with time ≤2 days and group 2 with time >2 days. A 2-by-2 contingency table and Fisher's exact test were used to evaluate the association between complications and time to surgery groups, and multivariate logistic regression was used to adjust for demographics and known risk factors.Results:A total of 263 patients (80% females) with a mean age of 73.9 ± 12.0 years were identified receiving PPF surgery, among which 216 patients were in group 1 and 47 patients in group 2. Complications in group 1 included 3 (1.4%) superficial infections (SI), 1 (0.5%) organ space infection (OSI), 1 (0.5%) wound dehiscence (WD), and 4 (1.9%) deep vein thrombosis (DVT);while complications in group 2 included 1 (2.1%) SI, 1 (2.1%) OSI, 1 (2.1%) DVT, and no WD. No significant difference was detected in postoperative complications between the two groups. However, patients in group 2 were more likely (p = 0.0013) to receive blood transfusions (57.5%) than those in group 1 (32.4%).Conclusion:Our study indicates patients with delayed time to surgery have higher chance to receive blood transfusions, but no significant difference in postoperative complications (SI, OSI, WD, or DVT) between the two groups. | Sung Ro Lee Kevin Shrestha Jackson Staggers Peng Li Sameer M.Naranje Ashish Shah | 2018 | Chinese Journal of Traumatology2018，21，6： | 5 |
| 8 | 脑海绵状血管畸形临床诊疗指南概要:血管瘤联盟科学咨询委员会临床专家组基于系统文献评价的共识推荐显示文摘背景尽管脑海绵状血管畸形(cerebral cavernous malformation, CCM)的相关研究文献已相当丰富,但在诊断和治疗策略方面仍存在着争议。目的制订CCM诊疗指南。方法作为代表CCM患者和研究的患者支持团体,血管瘤联盟(www.angioma.org)召集了一个包括CCM临床专家在内的多学科写作组来帮助总结现有的CCM临床诊疗相关文献,重点关注5个主题:(1)流行病学和自然病程;(2)遗传检测和咨询;(3)诊断标准和影像学标准;(4)神经外科注意事项;(5)神经内科注意事项。写作组根据预定方案进行了文献回顾和证据评价,最终制定推荐意见,并且确立了共识、争议和知识空白。结果根据方法学标准从1983年1月1日至2014年9月31日期间公开发表的1 270篇文献中筛选出98篇,并确定了另外38篇近期或相关的文献。各主题作者利用这些文献总结了现有知识并形成了23项共识诊疗推荐,同时根据美国心脏协会/美国卒中协会标准进行了推荐强度(效应量)和证据水平(确定性估计)评级。其中,尚无A级证据(因为缺乏随机对照试验),B级证据11项(48%),C级证据12项(52%);Ⅰ级推荐8项(35%),Ⅱ级推荐10项(43%),Ⅲ级推荐5项(22%)。结论现有证据支持对CCM诊疗的推荐,但这些证据的级别和推荐强度普遍较低,因此需要进一步研究来帮助进行更好的临床实践并更新这些推荐。完整的推荐文档包括引用文献的纳入标准、关于各项推荐更详尽的评判标准以及各种争议和知识空白的总结,同样通过了同行评议并可在线获取(www.angioma.org/CCMGuidelines)。 | Amy Akers Rustam Al-Shahi Salman Issam A. Awad Kristen Dahlem Kelly Flemming Blaine Hart Helen Kim Ignacio Jusue-Torres Douglas Kondziolka Cornelia Lee Leslie Morrison Daniele Rigamonti Tania Rebeiz Elisabeth Toumier-Lasserve Darrel Waggoner Kevin Whitehead 鄂同舟 雷宇 倪伟 顾宇翔 | 2017 | 国际脑血管病杂志2017，25，7： | 4 |
| 9 | Gastrointestinal sarcoidosis associated with pneumatosis cystoides intestinalis显示文摘A 39-year-old male reported fevers,weight loss,watery loose stools,and decreased visual acuity in his right eye over the prior five years.He was pancytopenic,had an elevated American council on exercise level,total bilirubin,and alkaline phosphatase.Computed tomography revealed massive hepatosplenomegaly and emphysematous lung changes.Liver biopsy showed non caseating granulomas.The patient was diagnosed with extrapulmonary sarcoidosis and was treated with prednisone.The patient symptomatically improved but 5 mo later presented with abdominal pain caused by perforation of the cecum.He underwent a cecectomy and pathology revealed pneumatosis cystoides intestinalis.This represents the first reported association between pneumatosis cystoides intestinalis and sarcoidosis.The etiology of pneumatosis cystoides intestinalis in this case was likely multifactorial and involved both effects of the corticosteroids as well as the advanced nature of the gastrointestinal sarcoidosis.Furthermore this case has the unique features of emphysematous lung changes and pancytopenia which are uncommon with sarcoidosis. | Hussein Rahim Mubashir Khan Jay Hudgins Kevin Lee Lei Du Louis Amorosa | 2013 | World Journal of Gastroenterology2013，19，7： | 3 |
| 10 | Fungal diversity notes 367-490:taxonomic and phylogenetic contributions to fungal taxa显示文摘This is a continuity of a series of taxonomic papers where materials are examined,described and novel combinations are proposed where necessary to improve our traditional species concepts and provide updates on their classification.In addition to extensive morphological descriptions and appropriate asexual and sexual connections,DNA sequence data are also analysed from concatenated datasets(rDNA,TEF-a,RBP2 and b-Tubulin)to infer phylogenetic relationships and substantiate systematic position of taxa within appropriate ranks.Wherever new species or combinations are being proposed,we apply an integrative approach(morphological and molecular data as well as ecological features wherever applicable).Notes on 125 fungal taxa are compiled in this paper,including eight new genera,101 new species,two new combinations,one neotype,four reference specimens,new host or distribution records for eight species and one alternative morphs.The new genera introduced in this paper are Alloarthopyrenia,Arundellina,Camarosporioides,Neomassaria,Neomassarina,Neotruncatella,Paracapsulospora and Pseudophaeosphaeria.The new species are Alfaria spartii,Alloarthopyrenia italica,Anthostomella ravenna,An.thailandica,Arthrinium paraphaeospermum,Arundellina typhae,Aspergillus koreanus,Asterina cynometrae,Bertiella ellipsoidea,Blastophorum aquaticum,Cainia globosa,Camarosporioides phragmitis,Ceramothyrium menglunense,Chaetosphaeronema achilleae,Chlamydotubeufia helicospora,Ciliochorella phanericola,Clavulinopsis aurantiaca,Colletotrichum insertae,Comoclathris italica,Coronophora myricoides,Cortinarius fulvescentoideus,Co.nymphatus,Co.pseudobulliardioides,Co.tenuifulvescens,Cunninghamella gigacellularis,Cyathus pyristriatus,Cytospora cotini,Dematiopleospora alliariae,De.cirsii,Diaporthe aseana,Di.garethjonesii,Distoseptispora multiseptata,Dis.tectonae,Dis.tectonigena,Dothiora buxi,Emericellopsis persica,Gloniopsis calami,Helicoma guttulatum,Helvella floriforma,H.oblongispora,Hermatomyces subiculosa,Juncaceicola italica,Lactarius dirkii,Lentithecium unicellulare,Le.voraginesporum,Leptosphaeria cirsii,Leptosphaeria irregularis,Leptospora galii,Le.thailandica,Lindgomyces pseudomadisonensis,Lophiotrema bambusae,Lo.fallopiae,Meliola citri-maximae,Minimelanolocus submersus,Montagnula cirsii,Mortierella fluviae,Muriphaeosphaeria ambrosiae,Neodidymelliopsis ranunculi,Neomassaria fabacearum,Neomassarina thailandica,Neomicrosphaeropsis cytisi,Neo.cytisinus,Neo.minima,Neopestalotiopsis cocoe¨s,Neopestalotiopsis musae,Neoroussoella lenispora,Neotorula submersa,Neotruncatella endophytica,Nodulosphaeria italica,Occultibambusa aquatica,Oc.chiangraiensis,Ophiocordyceps hemisphaerica,Op.lacrimoidis,Paracapsulospora metroxyli,Pestalotiopsis sequoiae,Peziza fruticosa,Pleurotrema thailandica,Poaceicola arundinis,Polyporus mangshanensis,Pseudocoleophoma typhicola,Pseudodictyosporium thailandica,Pseudophaeosphaeria rubi,Purpureocillium sodanum,Ramariopsis atlantica,Rhodocybe griseoaurantia,Rh.indica,Rh.luteobrunnea,Russula indoalba,Ru.pseudoamoenicolor,Sporidesmium aquaticivaginatum,Sp.olivaceoconidium,Sp.pyriformatum,Stagonospora forlicesenensis,Stagonosporopsis centaureae,Terriera thailandica,Tremateia arundicola,Tr.guiyangensis,Trichomerium bambusae,Tubeufia hyalospora,Tu.roseohelicospora and Wojnowicia italica.New combinations are given for Hermatomyces mirum and Pallidocercospora thailandica.A neotype is proposed for Cortinarius fulvescens.Reference specimens are given for Aquaphila albicans,Leptospora rubella,Platychora ulmi and Meliola pseudosasae,while new host or distribution records are provided for Diaporthe eres,Di.siamensis,Di.foeniculina,Dothiorella iranica,Do.sarmentorum,Do.vidmadera,Helvella tinta and Vaginatispora fuckelii,with full taxonomic details.An asexual state is also reported for the first time in Neoacanthostigma septoconstrictum.This paper contributes to a more comprehensive update and improved identification of many ascomycetes and basiodiomycetes. | Kevin D.Hyde Sinang Hongsanan Rajesh Jeewon D.Jayarama Bhat Eric H.C.McKenzie E.B.Gareth Jones Rungtiwa Phookamsak Hiran A.Ariyawansa Saranyaphat Boonmee Qi Zhao Faten Awad Abdel-Aziz Mohamed A.Abdel-Wahab Supharat Banmai Putarak Chomnunti Bao-Kai Cui Dinushani A.Daranagama Kanad Das Monika C.Dayarathne Nimali Ide Silva Asha J.Dissanayake Mingkwan Doilom Anusha H.Ekanayaka Tatiana Baptista Gibertoni Aristóteles Góes-Neto Shi-Ke Huang Subashini C.Jayasiri Ruvishika S.Jayawardena Sirinapa Konta Hyang Burm Lee Wen-Jing Li Chuan-Gen Lin Jian-Kui Liu Yong-Zhong Lu Zong-Long Luo Ishara S.Manawasinghe Patinjareveettil Manimohan Ausana Mapook Tuula Niskanen Chada Norphanphoun Moslem Papizadeh Rekhani H.Perera Chayanard Phukhamsakda Christian Richter AndréL.C.Mde A.Santiago E.Ricardo Drechsler-Santos Indunil C.Senanayake Kazuaki Tanaka T.M.D.S.Tennakoon Kasun M.Thambugala Qing Tian Saowaluck Tibpromma Benjarong Thongbai Alfredo Vizzini Dhanushka N.Wanasinghe Nalin N.Wijayawardene Hai-Xia Wu Jing Yang Xiang-Yu Zeng Huang Zhang Jin-Feng Zhang Timur S.Bulgakov Erio Camporesi Ali H.Bahkali Mohammad A.Amoozegar Lidia Silva Araujo-Neta Joseph F.Ammirati Abhishek Baghela R.P.Bhatt Dimitar Bojantchev Bart Buyck Gladstone Alves da Silva Catarina Letícia Ferreira de Lima Rafael JoséVilela de Oliveira Carlos Alberto Fragoso de Souza Yu-Cheng Dai Bálint Dima Tham Thi Duong Enrico Ercole Fernando Mafalda-Freire Aniket Ghosh Akira Hashimoto Sutakorn Kamolhan Ji-Chuan Kang Samantha C.Karunarathna Paul M.Kirk Ilkka Kytovuori Angela Lantieri Kare Liimatainen Zuo-Yi Liu Xing-Zhong Liu Robert Lücking Gianfranco Medardi Peter E.Mortimer Thi Thuong Thuong Nguyen Itthayakorn Promputtha K.N.Anil Raj Mateus A.Reck Saisamorn Lumyong Seyed Abolhassan Shahzadeh-Fazeli Marc Stadler Mohammad Reza Soudi Hong-Yan Su Takumasa Takahashi Narumon Tangthirasunun Priyanka Uniyal Yong Wang Ting-Chi Wen Jian-Chu Xu Zhong-Kai Zhang Yong-Chang Zhao Jun-Liang Zhou Lin Zhu | 2016 | Fungal Diversity2016，，5： | 2 |
| 11 | Fungal diversity notes 111-252-taxonomic and phylogenetic contributions to fungal taxa显示文摘This paper is a compilation of notes on 142 fungal taxa,including five new families,20 new genera,and 100 new species,representing a wide taxonomic and geographic range.The new families,Ascocylindricaceae,Caryosporaceae and Wicklowiaceae(Ascomycota)are introduced based on their distinct lineages and unique morphology.The new Dothideomycete genera Pseudomassariosphaeria(Amniculicolaceae),Heracleicola,Neodidymella and Pseudomicrosphaeriopsis(Didymellaceae),Pseudopithomyces(Didymosphaeriaceae),Brunneoclavispora,Neolophiostoma and Sulcosporium(Halotthiaceae),Lophiohelichrysum(Lophiostomataceae),Galliicola,Populocrescentia and Vagicola(Phaeosphaeriaceae),Ascocylindrica(Ascocylindricaceae),Elongatopedicellata(Roussoellaceae),Pseudoasteromassaria(Latoruaceae)and Pseudomonodictys(Macrodiplodiopsidaceae)are introduced.The newly described species of Dothideomycetes(Ascomycota)are Pseudomassariosphaeria bromicola(Amniculicolaceae),Flammeascoma lignicola(Anteagloniaceae),Ascocylindrica marina(Ascocylindricaceae),Lembosia xyliae(Asterinaceae),Diplodia crataegicola and Diplodia galiicola(Botryosphaeriaceae),Caryospora aquatica(Caryosporaceae),Heracleicola premilcurensis and Neodidymella thailandicum(Didymellaceae),Pseudopithomyces palmicola(Didymosphaeriaceae),Floricola viticola(Floricolaceae),Brunneoclavispora bambusae,Neolophiostoma pigmentatum and Sulcosporium thailandica(Halotthiaceae),Pseudoasteromassaria fagi(Latoruaceae),Keissleriella dactylidicola(Lentitheciaceae),Lophiohelichrysum helichrysi(Lophiostomataceae),Aquasubmersa japonica(Lophiotremataceae),Pseudomonodictys tectonae(Macrodiplodiopsidaceae),Microthyrium buxicola and Tumidispora shoreae(Microthyriaceae),Alloleptosphaeria clematidis,Allophaeosphaeria cytisi,Allophaeosphaeria subcylindrospora,Dematiopleospora luzulae,Entodesmium artemisiae,Galiicola pseudophaeosphaeria,Loratospora luzulae,Nodulosphaeria senecionis,Ophiosphaerella aquaticus,Populocrescentia forlicesenensis and Vagicola vagans(Phaeosphaeriaceae),Elongatopedicellata lignicola,Roussoella magnatum and Roussoella angustior(Roussoellaceae)and Shrungabeeja longiappendiculata(Tetraploasphaeriaceae).The new combinations Pseudomassariosphaeria grandispora,Austropleospora archidendri,Pseudopithomyces chartarum,Pseudopithomyces maydicus,Pseudopithomyces sacchari,Vagicola vagans,Punctulariopsis cremeoalbida and Punctulariopsis efibulata Dothideomycetes.The new genera Dictyosporella(Annulatascaceae),and Tinhaudeus(Halosphaeriaceae)are introduced in Sordariomycetes(Ascomycota)while Dictyosporella aquatica(Annulatascaceae),Chaetosphaeria rivularia(Chaetosphaeriaceae),Beauveria gryllotalpidicola and Beauveria loeiensis(Cordycipitaceae),Seimatosporium sorbi and Seimatosporium pseudorosarum(Discosiaceae),Colletotrichum aciculare,Colletotrichum fusiforme and Colletotrichum hymenocallidicola(Glomerellaceae),Tinhaudeus formosanus(Halosphaeriaceae),Pestalotiopsis subshorea and Pestalotiopsis dracaenea(Pestalotiopsiceae),Phaeoacremonium tectonae(Togniniaceae),Cytospora parasitica and Cytospora tanaitica(Valsaceae),Annulohypoxylon palmicola,Biscogniauxia effusae and Nemania fusoideis(Xylariaceae)are introduced as novel species to order Sordariomycetes.The newly described species of Eurotiomycetes are Mycocalicium hyaloparvicellulum(Mycocaliciaceae).Acarospora septentrionalis and Acarospora castaneocarpa(Acarosporaceae),Chapsa multicarpa and Fissurina carassensis(Graphidaceae),Sticta fuscotomentosa and Sticta subfilicinella(Lobariaceae)are newly introduced in class Lecanoromycetes.In class Pezizomycetes,Helvella pseudolacunosa and Helvella rugosa(Helvellaceae)are introduced as new species.The new families,Dendrominiaceae and Neoantrodiellaceae(Basidiomycota)are introduced together with a new genus Neoantrodiella(Neoantrodiellaceae),here based on both morphology coupled with molecular data.In the class Agaricomycetes,Agaricus pseudolangei,Agaricus haematinus,Agaricus atrodiscus and Agaricus exilissimus(Agaricaceae),Amanita melleialba,Amanita pseudosychnopyramis and Amanita subparvipantherina(Amanitaceae),Entoloma calabrum,Cora barbulata,Dictyonema gomezianum and Inocybe granulosa(Inocybaceae),Xerocomellus sarnarii(Boletaceae),Cantharellus eucalyptorum,Cantharellus nigrescens,Cantharellus tricolor and Cantharellus variabilicolor(Cantharellaceae),Cortinarius alboamarescens,Cortinarius brunneoalbus,Cortinarius ochroamarus,Cortinarius putorius and Cortinarius seidlii(Cortinariaceae),Hymenochaete micropora and Hymenochaete subporioides(Hymenochaetaceae),Xylodon ramicida(Schizoporaceae),Colospora andalasii(Polyporaceae),Russula guangxiensis and Russula hakkae(Russulaceae),Tremella dirinariae,Tremella graphidis and Tremella pyrenulae(Tremellaceae)are introduced.Four new combinations Neoantrodiella gypsea,Neoantrodiella thujae(Neoantrodiellaceae),Punctulariopsis cremeoalbida,Punctulariopsis efibulata(Punctulariaceae)are also introduced here for the division Basidiomycota.Furthermore Absidia caatinguensis,Absidia koreana and Gongronella koreana(Cunninghamellaceae),Mortierella pisiformis and Mortierella formosana(Mortierellaceae)are newly introduced in the Zygomycota,while Neocallimastix cameroonii and Piromyces irregularis(Neocallimastigaceae)are introduced in the Neocallimastigomycota.Reference specimens or changes in classification and notes are provided for Alternaria ethzedia,Cucurbitaria ephedricola,Austropleospora,Austropleospora archidendri,Byssosphaeria rhodomphala,Lophiostoma caulium,Pseudopithomyces maydicus,Massariosphaeria,Neomassariosphaeria and Pestalotiopsis montellica. | Hiran A.Ariyawansa Kevin D.Hyde Subashini C.Jayasiri Bart Buyck K.W.Thilini Chethana Dong Qin Dai Yu Cheng Dai Dinushani A.Daranagama Ruvishika S.Jayawardena Robert Lücking Masoomeh Ghobad-Nejhad Tuula Niskanen Kasun M.Thambugala Kerstin Voigt Rui Lin Zhao Guo-Jie Li Mingkwan Doilom Saranyaphat Boonmee Zhu L.Yang Qing Cai Yang-Yang Cui Ali H.Bahkali Jie Chen Bao Kai Cui Jia Jia Chen Monika C.Dayarathne Asha J.Dissanayake Anusha H.Ekanayaka Akira Hashimoto Sinang Hongsanan E.B.Gareth Jones Ellen Larsson Wen Jing Li Qi-Rui Li Jian Kui Liu Zong Long Luo Sajeewa S.N.Maharachchikumbura Ausana Mapook Eric H.C.McKenzie Chada Norphanphoun Sirinapa Konta Ka Lai Pang Rekhani H.Perera Rungtiwa Phookamsak Chayanard Phukhamsakda Umpava Pinruan Emile Randrianjohany Chonticha Singtripop Kazuaki Tanaka Cheng Ming Tian Saowaluck Tibpromma Mohamed A.Abdel-Wahab Dhanushka N.Wanasinghe Nalin N.Wijayawardene Jin-Feng Zhang Huang Zhang Faten A.Abdel-Aziz Mats Wedin Martin Westberg Joseph F.Ammirati Timur S.Bulgakov Diogo X.Lima Tony M.Callaghan Philipp Callac Cheng-Hao Chang Luis F.Coca Manuela Dal-Forno Veronika Dollhofer Kateřina Fliegerová Katrin Greiner Gareth W.Griffith Hsiao-Man Ho Valerie Hofstetter Rajesh Jeewon Ji Chuan Kang Ting-Chi Wen Paul M.Kirk Ilkka Kytövuori James D.Lawrey Jia Xing Hong Li Zou Yi Liu Xing Zhong Liu Kare Liimatainen H.Thorsten Lumbsch Misato Matsumura Bibiana Moncada Salilaporn Nuankaew Sittiporn Parnmen AndréL.C.M.de Azevedo Santiago Sujinda Sommai Yu Song Carlos A.F.de Souza Cristina M.de Souza-Motta Hong Yan Su Satinee Suetrong Yong Wang Syuan-Fong Wei Ting Chi Wen Hai Sheng Yuan Li Wei Zhou Martina Réblová Jacques Fournier Erio Camporesi J.Jennifer Luangsa-ard Kanoksri Tasanathai Artit Khonsanit Donnaya Thanakitpipattana Sayanh Somrithipol Paul Diederich Ana M.Millanes Ralph S.Common Marc Stadler Ji Ye Yan XingHong Li Hye Won Lee Thi T.T.Nguyen Hyang Burm Lee Eliseo Battistin Orlando Marsico Alfredo Vizzini Jordi Vila Enrico Ercole Ursula Eberhardt Giampaolo Simonini Hua-An Wen Xin-Hua Chen Otto Miettinen Viacheslav Spirin Hernawati | 2015 | Fungal Diversity2015，，6： | 2 |
| 12 | C-reactive protein and radiographic findings of lower respiratory tract infection in infants显示文摘AIM To evaluate the association between C-reactive protein(CRP) and radiological evidence of lower respiratory tract infection(LRTI) in infants.METHODS All patients aged less than 4 years who presented with suspected lower respiratory tract infection,who received a peri-presentation chest radiograph and CRP blood measurement over an 18-mo period were included in the study.Age,gender,source of referral,CRP,white cell count,neutrophil count along with the patients' symptoms and radiologist's report were recorded.RESULTS Three hundred and eleven patients met the inclusioncriteria.Abnormal chest radiographs were more common in patients with elevated CRP levels(P < 0.01).Radiologic signs of LRTI were identified in 73.7% of chest radiographs when a patient had a CRP level between 50-99 mg/L.CRP levels were a better predictor of positive chest radiograph findings for those aged greater than I year compared to those 1 year or less.CONCLUSION CRP may be used in patients with suspected LRTI diagnosis to select those who are likely to have positive findings on chest radiograph,thus reducing unnecessary chest radiographs. | Maria Twomey Hannah Fleming Fiachra Moloney Kevin P Murphy Lee Crush Siobhan B O’Neill Oisin Flanagan Karl James Conor Bogue Owen J O’Connor Michael M Maher | 2017 | World Journal of Radiology2017，9，4： | 2 |
| 13 | Hepatitis B virus reactivation in B-cell lymphoma patients treated with rituximab: Analysis from the Asia Lymphoma Study Group显示文摘 | Seok Jin Kim Chiun Hsu Yu-Qin Song Kevin Tay Xiao-Nan Hong Junning Cao Jin Seok Kim Hyeon Seok Eom Joon Hyeok Lee Jun Zhu Kian-Meng Chang Arry Harryanto Reksodiputro Daryl Tan Yeow Tee Goh Jejung Lee Tanin Intragumtornchai Wee-Joo Chng Ann-Lii Cheng Soon | 2013 | European Journal of Cancer2013，，： | 2 |
| 14 | Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock显示文摘 | Jonas Sundén-Cullberg Anna Norrby-Teglund Ari Rouhiainen Heikki Rauvala Gunilla Herman Kevin J. Tracey Martin L. Lee Jan Andersson Leif Tokics Carl Johan Treutiger | 2005 | Critical Care Medicine2005，，3： | 2 |
| 15 | Identifying Important Predictors for Anastomotic Leak After Colon and Rectal Resection: Prospective Study on 616 Patients显示文摘 | Koianka Trencheva Kevin P. Morrissey Martin Wells Carol A. Mancuso Sang W. Lee Toyooki Sonoda Fabrizio Michelassi Mary E. Charlson Jeffrey W. Milsom | 2013 | Annals of Surgery2013，，1： | 2 |
| 16 | Hepcidin contributes to Swedish mutant APP-induced osteoclastogenesis and trabecular bone loss显示文摘Patients with Alzheimer’s disease(AD)often have lower bone mass than healthy individuals.However,the mechanisms underlying this change remain elusive.Previously,we found that Tg2576 mice,an AD animal model that ubiquitously expresses Swedish mutant amyloid precursor protein(APPswe),shows osteoporotic changes,reduced bone formation,and increased bone resorption.To understand how bone deficits develop in Tg2576 mice,we used a multiplex antibody array to screen for serum proteins that are altered in Tg2576 mice and identified hepcidin,a master regulator of iron homeostasis.We further investigated hepcidin’s function in bone homeostasis and found that hepcidin levels were increased not only in the serum but also in the liver,muscle,and osteoblast(OB)lineage cells in Tg2576 mice at both the mRNA and protein levels.We then generated mice selectively expressing hepcidin in hepatocytes or OB lineage cells,which showed trabecular bone loss and increased osteoclast(OC)-mediated bone resorption.Further cell studies suggested that hepcidin increased OC precursor proliferation and differentiation by downregulating ferroportin(FPN)expression and increasing intracellular iron levels.In OB lineage cells,APPswe enhanced hepcidin expression by inducing ER stress and increasing OC formation,in part through hepcidin.Together,these results suggest that increased hepcidin expression in hepatocytes and OB lineage cells in Tg2576 mice contributes to enhanced osteoclastogenesis and trabecular bone loss,identifying the hepcidin-FPN-iron axis as a potential therapeutic target to prevent AD-associated bone loss. | Hao-Han Guo Lei Xiong Jin-Xiu Pan Daehoon Lee Kevin Liu Xiao Ren Bo Wang Xiao Yang Shun Cui Lin Mei Wen-Cheng Xiong | 2021 | Bone Research2021，9，3： | 2 |
| 17 | Novel de novo mutations of the interleukin-10 receptor gene lead to infantile onset inflammatory bowel disease显示文摘 | Cheng Hiang Lee Peter Hsu Brigitte Nanan Ralph Nanan Melanie Wong Kevin J. Gaskin Rupert W. Leong Ryan Murchie Aleixo M. Muise Michael O. Stormon | 2014 | Journal of Crohn’s and Colitis2014，，： | 2 |
| 18 | Spatially continuous six degree of freedom position and orientation sensor 显示文摘 | LEE D KEVIN E ANDREW T | 1999 | Sensors Review1999，19，2： | 1 |
| 19 | Fed-batch two-phase production of alanineby a metabolically engineered Escherichia coli显示文摘 | Geoffrey M. Smith Sarah A. Lee Kevin C. Reilly Mark A. Eiteman Elliot Altman | 2006 | Biotechnology Letters2006，，20： | 1 |
| 20 | Modeling uncertainty reasoning with possibilistic Petri nets显示文摘 | Lee Jonathan Liu Kevin F R Chiang Wei-ling | 2003 | IEEE Trans on Systems Man and Cybernetics-Part B:Cybernetics2003，33，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员