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| 1 | Impact of preoperative chemoradiotherapy on survival in patients with resectable pancreatic cancer显示文摘AIM:To explore whether preoperative chemoradiation therapy improves survival of patients with pancreatic cancer undergoing resectional surgery. METHODS:Forty-seven patients with a malignant pancreatic tumor localized in the head or uncinate process of the pancreas underwent radical pancreaticoduodenectomy. Twenty-two received chemoradiation therapy (gemcitabine and radiation dose 50.4 Gy) before surgery (CRR) and 25 patients underwent surgery only (RO). The study was non-randomised. Patients were identified from a prospective database. RESULTS:The median survival time was 30.2 mo in the CRR group and 35.9 mo in the RO group. No statistically significant differences were found in subclasses according to lymph node involvement,TNM stages,tumor size,or perineural invasion. The one,three and five year survival rates were 81%,33% and 33%,respectively,in the CRR group and 72%,47% and 23%,respectively,in the RO group. In ductal adenocarcinoma,the median survival time was 27 mo in the CRR group and 20 mo in the RO group. No statistically significant differences were found in the above subclasses. The one,three and five year survival rates were 79%,21% and 21%,respectively,in the CRR group and 64%,50% and 14%,respectively,in the RO group. The overall hospital mortality rate was 2%. The morbidity rate was 45% in the CRR group and 32% (NS) in the RO group. CONCLUSION:Major multicenter randomized studies are needed to conclusively assess the impact of neoadjuvant treatment in the management of pancreatic cancer. | Plvi Vento Harri Mustonen Timo Joensuu Pivi Krkkinen Eero Kivilaakso Tuula Kiviluoto | 2007 | World Journal of Gastroenterology2007，13，21： | 8 |
| 2 | Serum phospholipase A2 and pulmonary changes in acute fulminant pancreatitis显示文摘 | Schroder T Lempinen M Kivilaakso E | 1982 | Resuscitation1982，10，2： | 1 |
| 3 | Duodenal diverticulum at endoscopic retrograde cholangiopancratography,analysis of 123 patients显示文摘 | Leivonen MK Halttunen JA Kivilaakso EO | 1996 | Hepatogastroenterology1996，43，10： | 1 |
| 4 | Castric changes in coronary-op-erated patients with low-dose aspirin显示文摘 | Eivinen M Sipponen P kivilaakso E | 1992 | Scand j Gastroerol1992，27，： | 1 |
| 5 | Urinary trypsinogen-2 test strip for acute pancreatitis显示文摘 | J Hedst?m U-H Stenman A Korvuo P Kenkim?ki S Tikanoja R Haapiainen E Kivilaakso | 1996 | The Lancet1996，，9003： | 1 |
| 6 | Serum Trypsinogen-2 in the Prediction of Outcome in Acute Necrotizing Pancreatitis显示文摘 | V. Sainio P. Puolakkainen E. Kemppainen J. Hedstr?m R. Haapiainen L. Kivisaari U.-H. Stenman T. Schr?der E. Kivilaakso | 1996 | Scandinavian Journal of Gastroenterology1996，，8： | 1 |
| 7 | Early antibiotic treatment in acute necrotising pancreatitis显示文摘 | V Sainio E Kemppainen P Puolakkainen R Haapiainen T Schr?der E Kivilaakso V Valtonen M Taavitsainen L Kivisaarl | 1995 | The Lancet1995，，8976： | 1 |
| 8 | Basement membrane laminin 5 is deposited in colorectal adenomas and carcinomas and serves as a ligand for alpha3 betal integrin 显示文摘 | Lohi J Oivula J Kivilaakso E | 2000 | APMIS2000，108，3： | 1 |
| 9 | Topical prostaglandin E2 protects isolated gastric mucosa against acidified taurocholate-,but not ethanol-or aspirin-induced injury显示文摘 | Ranta-Knuuttila T Mustonen H Kivilaakso E | | 0，，01： | 1 |
| 10 | Papillary Cystic Tumor of the Pancreas: An Analysis of Cellular Differentiation by Electron Microscopy and Immunohistochemistry显示文摘 | Markku Miettinen Seppo Partamen Olavi Fraki Eero Kivilaakso | 1987 | The American Journal of Surgical Pathology1987，，11： | 1 |
| 11 | Ethanol induces volume changes and gap junction closure via intracellular Ca2+ signalling pathway in cultured rabbit gastric epithelial cells显示文摘 | Mustonen H Kiviluoto T Puolakkainen P Kivilaakso E | 2004 | Scand J Gastroenterol2004，39，： | 1 |
| 12 | Decreased risk of gastric stump carcinoma after partial gastrectomy supplemented with bile diversion显示文摘 | LUOKKONEN P KIVILAAKSO E | 1999 | Hepato-Gastroenteloligy1999，37，： | 1 |
| 13 | Increased risk of colorectal cancer after choiecystectomy 显示文摘 | Turunen MJ Kivilaakso EO | 1981 | Ann Surg1981，194，： | 1 |
| 14 | Basement membrane laminin-5 is deposited in colorectal adenomas and carcinomas and serves as a ligand for alpha3 beta1 integrin显示文摘 | Oivula J Kivilaakso E | 2000 | APMIS2000，108，3： | 1 |
| 15 | A new method for the diagnosis of acute hemorrhagic-necrotizing pancreatitis using contrast-enhanced CT显示文摘 | Leena Kivisaari M.D. Kalevi Somer Carl-Gustaf Standertskj?ld-Nordenstam Tom Schr?der Eero Kivilaakso Matti Lempinen | 1984 | Gastrointestinal Radiology1984，，1： | 1 |
| 16 | Basement membrane laminin-5 is deposited in colorectal adenomas and carcinomas and serves as a ligand for alpha3beta1 integrin显示文摘 | Lohi J Oivula J Kivilaakso E | 2000 | APMIS2000，108，3： | 1 |
| 17 | Increased risk of colorectal cancer after cholecystectomy显示文摘 | Turunen MJ Kivilaakso EO | 1991 | Ann Surg1991，194，5： | 1 |
| 18 | Gastric carcinoma显示文摘 | KIVILAAKSO E | 2006 | Scand J Surg2006，95，4： | 1 |
| 19 | Increased risk of colorectal cancer after cholecystectomy显示文摘 | Turunen MJ Kivilaakso EO | 1981 | Ann Surg1981，194，： | 1 |
| 20 | Resection of the pancreas for acute fulminant pancreatitis显示文摘 | Kivilaakso E Fraki O Nikki P | 1981 | Surg Gynecol Obstet1981，152，4： | 1 |
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