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	题名	作者	年代	出处	被引量
1	Endoscopic sphincterotomy in patients with stenosis of ampulla of Vater:Three-year follow-up of exocrine pancreatic function and clinical symptoms显示文摘AIM: To investigate retrospectively the long-term effect of endoscopic sphincterotomy (ES) including exocrine pancreatic function in patients with stenosis of ampulla of Vater. METHODS: After diagnostic endoscopic retrograde cholangiopancreatography (ERCP) and ES because of stenosis of the ampulla of Vater (SOD Type Ⅰ), follow-up examinations were performed in 60 patients (mean follow-up time 37.7 mo). Patients were asked about clini-cal signs and symptoms at present and before interven-tion using a standard questionnaire. Before and after ES exocrine pancreatic function was assessed by determina-tion of immunoreactive fecal elastase 1. Serum enzymes indicating cholestasis as well as serum lipase and amy-lase were measured. RESULTS: Eighty percent of patients reported an im-provement in their general condition after ES. The fecal elastase 1 concentrations (FEC) in all patients increased significantly after ES. This effect was even more marked in patients with pathologically low concentrations (< 200 μg/g) of fecal elastase prior to ES. The levels of serum lipase and amylase as well as serum alcaline phosphatase (AP) and gamma-glutamyltranspeptidase (GGT) decreased signifi-cantly after ES. CONCLUSION: The results of this study demonstrate that patients with stenosis of the ampulla of Vater can be successfully treated with endoscopic sphincterotomy. The positive effect is not only indicated by sustained improvement of clinical symptoms and cholestasis but also by improvement of exocrine pancreatic function.	Nils Ewald Axel Michael Marzeion Reinhard Georg Bretzel Hans Ulrich Kloer Philip Daniel Hardt	2007	World Journal of Gastroenterology2007，13，6：	5
2	Severe hypertriglyceridemi and pancreatits:presentation and management显示文摘	Ewald N Hardt PD Kloer HU	2009	Curr Opin lipidol2009，20，6：	1
3	Severe hypertrigly-ceridemia and pancreatitis:presentation and management 显示文摘	Ewald N Hardt PD Kloer HU	2009	Curr Opin Lipidol2009，20，6：	1
4	Evalution of serum levels of solubilized adhssion molecules and cy- tokine receptors in coronary heart disease显示文摘	PORSCH-OEZCUERUEMEZ M KUNZ D KLOER H U	1999	J Am Coll Cardiol1999，34，：	1
5	Evaluation of serum levels of solubilized adhesion molecules and cytokine receptors in coronary heart disease显示文摘	Kunz D Kloer HU	1999	J Am Coll Cardiol1999，34，7：	1
6	Modulation of lipoprotein lipase activity by apolipoproteins : Effect of apo- lipoprotein C-III 显示文摘	Wang CS McConathy WJ Kloer HU	1985	J Clin Invest1985，75，2：	1
7	The structure of a retinal- forming carotenoid oxygenase 显示文摘	Kloer D P Ruch S A1-Babili S	2005	Science2005，308，5719：	1
8	Severe hypertriglyceridemia and pancreatitis: presentation and management显示文摘	Ewald N Hardt PD Kloer HU	2009	Curr Opin Lipidol2009，20，6：	1
9	High Prevalence of Steatorrhea in 101 Diabetic Patients Likely to Suffer from Exocrine Pancreatic Insufficiency According to Low Fecal Elastase 1 Concentrations: A Prospective Multicenter Study显示文摘	Philip D. Hardt Annette Hauenschild Clemens Jaeger Joachim Teichmann Reinhard G. Bretzel Hans U. Kloer The S2453112/S2453113 Study Group	2003	Digestive Diseases and Sciences2003，，9：	1
10	A review of novel biologieal tools used in sereening for the early detection of lung cancer 显示文摘	Ghosal R Kloer P Lewis KE	2009	Postgrad Med J2009，85，1005：	1
11	Structural and biological aspects of carotenoid cleavage 显示文摘	KLOER D P SCHULZ G E	2006	Cellular and Molec- ular Life Sciences2006，63，1920：	1
12	Diagnostic Relevance of Interleukin Pattern, Acute-Phase Proteins, and Procalcitonin in Early Phase of Post-ERCP Pancreatitis显示文摘	M. Oezcueruemez-Porsch D. Kunz P. D. Hardt T. Fadgyas O. Kress H. U. Schulz H. Schnell-Kretschmer H. Temme S. Westphal C. Luley H. U. Kloer	1998	Digestive Diseases and Sciences1998，，8：	1
13	Evaluation of serum:levels of solubilized adhesion molecules and cytokine receptors in coronary heart disease显示文摘	M Kunz d Kloer HU Luley C	1999	J Am Coil Cardiol1999，34，：	1
14	Structural and biological aspects of carote- noid cleavage显示文摘	Kloer Dp Schulz Ge	2006	Cell Mol Life Sci2006，63，1920：	1
15	Severe hypertriglyceridemia and pancreatitis: presentation and management 显示文摘	Ewald N Hardt PD Kloer HU	2009	Curr Opin Lipidol2009，20，6：	1
16	Severe hypertriglyceridemia and pancreatitis:presentation and management显示文摘	Ewald N Hardt PD Kloer HU		0，，06：	1
17	Effects of oral fat load on insulin output and glucose tolerance in healthy control subjects and obese patients without diabetes显示文摘	Wuesten O Kloer HG Balz CH	2005	Diabetes Care2005，28，2：	1
18	Is pancreatic diabetes (type 3c diabetes) underdiagnosed and misdiagnosed显示文摘	Hardt PD Brendel MD Kloer HU		0，，2：	1
19	Severe hypertriglyceridemia and pancreatitis:presentation and management显示文摘	Ewald N Hardt PD Kloer HU	2009	Curr Opin Lipidol2009，20，6：	1
20	Severe hy- pertriglyceridemia and pancreatitis: presentation and management显示文摘	EWALD N HARDT P D KLOER H U	2009	Curr Opin Lipidol2009，20，：	1

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