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| 1 | Progresses on microwave remote sensing of land surface parameters显示文摘Highly accurate observations at various scales on the land surface are urgently needed for the studies of many areas,such as hydrology,meteorology,and agriculture.With the rapid development of remote sensing techniques,remote sensing has had the capacity of monitoring many factors of the Earth's land surface.Especially,the space-borne microwave remote sensing systems have been widely used in the quantitative monitoring of global snow,soil moisture,and vegetation parameters with their all-weather,all-time observation capabilities and their sensitivities to the characteristics of land surface factors.Based on the electromagnetic theories and microwave radiative transfer equations,researchers have achieved great successes in the microwave remote sensing studies for different sensors in recent years.This article has systematically reviewed the progresses on five research areas including microwave theoretical modeling,microwave inversion on soil moisture,snow,vegetation and land surface temperatures.Through the further enrichment of remote sensing datasets and the development of remote sensing theories and inversion techniques,remote sensing including microwave remote sensing will play a more important role in the studies and applications of the Earth systems. | SHI JianCheng DU Yang DU JinYang JIANG LingMei CHAI LinNa MAO KeBiao XU Peng NI WenJian XIONG Chuan LIU Qiang LIU ChenZhou GUO Peng CUI Qian LI YunQing CHEN Jing WANG AnQi LUO HeJia WANG YinHui | 2012 | Science China Earth Sciences2012，55，7： | 24 |
| 2 | Zscan4 promotes genomic stability during reprogramming and dramatically improves the quality of iPS cells as demonstrated by tetraploid complementation显示文摘用 Yamanaka 因素产生的导致的 pluripotent 茎(iPS ) 细胞在自体同源的细胞治疗为使用有大潜力。然而, genomic 畸形充分在人的 iPS 房间,和房间不是的大多数老鼠 iPS 存在 pluripotent 由 tetraploid 互补试金评估了 TCA ) ;这很可能与 DNA 损坏反应(DDR ) 被联系在 Yamanaka 因素导致的早 reprogramming 发生了。相反,原子转移忠实地装改编体的房间进胚胎的茎(ES ) 满足 TCA 的房间。我们因此假设了涉及导致卵母细胞的 reprogramming 的因素可以在 reprogramming 期间稳定体的染色体,并且改进结果的 iPS 房间的质量。测试这个假设,我们在 iPS 期间为能减少的因素屏蔽了 DDR 信号房间正式就职。我们决定了那 Zscan4,在有 Yamanaka 因素的联合,不是仅仅显著地减少了 DDR 而且显著地支持了 iPS 房间产生的效率。Zscan4 的包括稳定了 genomic DNA,导致 p53 downregulation。而且, Zscan4 也提高了象通过 telomere 感染以后的 3 天一样早变长的 telomere 基于再结合的机制。作为结果,与 Zscan4 的增加产生的 iPS 房间比古典 iPS 房间展出了更长的 telomeres。惊人地,超过 50% iPS 房间线(11/19 ) 经由这生产了 “ Zscan4 protocol”产生了由 TCA 决定了的实时熊的 all-iPS 房间老鼠,与为用古典 Yamanaka 因素生产的线的 1/12 相比。我们的调查结果提供在 reprogramming 期间维持 genomic 稳定性支持的第一示范高质量的 iPS 房间的产生。 | Jing Jiang Wenjian Lv Xiaoying Ye Lingbo Wang Man Zhang Hui Yang Maja Okuka Chikai Zhou Xuan Zhang Lin Liu Jinsong Li | 2013 | Cell Research2013，23，1： | 14 |
| 3 | Carbon and oxygen isotopes analyses for the Sinian carbonates in the Helan Mountain, North China显示文摘We conducted detailed studies of the Sinian carbonates from the Helan Mountain,Ningxia by both field investigation and laboratory analyses of carbon and oxygen isotopes.The carbon isotopic compositions of the Sinian Zhengmuguan Formation shows variations with regularity in the five studied sections,theδ13C values all gradually decrease from bottom to top,with a total range from 4.51‰to 0.11‰,and the biggest negative excursion reaches up to 6.88‰.In addition,abundant macro-body fossils were also found from the Tuerkeng Formation in this study,similar to those found from the Dengying Formation in the South China Block.This observation firmly constrained the age for the Zhengmuguan and Tuerkeng formations to the Sinian period.Here we interpreted that the Zhengmuguan Formation formed during a glacial period when the extremely cold climate substantially decreased the amount of burial of organic matter in the ocean and thus led to the general negativeδ13C excursion.The increasingδ13C values in the Tuerkeng Formation dolomites imply the ending of the glacial period in the Zhengmuguan epoch,biological recovery and increase of organic matter burial in the ocean occurred during this period.Comparing our obtained carbon and oxygen isotopes of the Zhengmuguan and Tuerkeng formations with those of coeval carbonate successions from other places all over the world,the Zhengmuguang-aged glacial deposits might be deposited after the Gaskiers glaciation.This study provides important information for paleo-ocean,paleogeographic and biological evolution in the North China Block during the Ediacaran period and adds new carbon and oxygen isotopes data for the global Sinian carbon-oxygen isotopes dataset. | YANG Jie ZENG ZuoXun CAI XiongFei LI ZhiYong LI TianBin MENG Fang HE WenJian | 2013 | Chinese Science Bulletin2013，58，32： | 8 |
| 4 | Effects of future land use change on the regional climate in China显示文摘Land use and land cover change(LUCC)is one of the important human forcing on climate.However,it is difficult to infer how LUCC will affect climate in the future from the effects of previous LUCC on regional climates in the past.Thus,based on the land cover data recommended by the Coupled Model Intercomparison Project Phase 5(CMIP5),a regional climate model(Reg CM4)was used to investigate the climate effects of future land use change over China.Two 15-year simulations(2036–2050),one with the current land use data and the other with future land cover scenario(2050)were conducted.It is noted that future LUCC in China is mainly characterized by the transition from the grassland to the forest.Results suggest that the magnitudes and ranges of the changes in temperature and precipitation caused by future LUCC show evident seasonality,which are more prominent in summer and autumn.Significant response of climate to future LUCC mainly happens in Northeast China,North China,the Hetao Area,Eastern Qinghai-Tibetan Plateau and South China.Further investigation shows that future LUCC can also produce significant impacts on the atmospheric circulation.LUCC results in abnormal southwesterly wind over extensive areas from the Indian peninsula to the coasts of the South China Sea and South China through the Bay of Bengal.Furthermore,Indian tropical southwest monsoons and South Sea southwest monsoons will both be strong,and the abnormal water vapor convergence from the South China Sea and the Indian Ocean will result in more precipitation in South China. | HUA WenJian CHEN HaiShan LI Xing | 2015 | Science China Earth Sciences2015，58，10： | 8 |
| 5 | Ultra-sensitive graphene strain sensor for sound signal acquisition and recognition显示文摘为健全信号获得和识别的一个便携、高精确的传感器从编织的特殊设计的 graphene 的薄电影被制作织物(GWF ) 。在被拉长之上,随机的裂缝的高密度出现在网络,它减少当前的小径,从而增加电阻。因此,这部电影能对人的喉咙作为一个紧张传感器起作用以便测量通过肌肉运动,一个声音是否被生产的讲话。超离频敏感允许由提取声波的签名特征的快速、低频率的讲话采样的实现。在这研究, 26 封英语信,典型汉字和音调的代表性的信号,甚至短语和句子被测试,揭示在电阻的明显、典型的变化。而且, graphene 传感器的电阻变化与预告录下的声音完美地反应了。由把人工智能与数字信号处理相结合,我们期望以后,这个 graphene 传感器将能成功地达成复杂声学的系统和听觉的数据的大数量。 | Yan Wang Tingting Yang Junchao Lao Rujing Zhang Yangyang Zhang Miao Zhu Xiao Li Xiaobei Zang Kunlin Wang Wenjian YU Hu Jin Li Wang Hongwei Zhu | 2015 | Nano Research2015，8，5： | 8 |
| 6 | Resveratrol reduces intracellular reactive oxygen species levels by inducing autophagy through the AMPK-mTOR pathway显示文摘Oxidative stress induced by free fatty acid aggravates endothelial injury,which leads to diabeti cardiovascular complications.Reduction of intracellular oxidative stress may attenuate these pathogeni processes.The dietary polyphenol resveratrol reportedly exerts potential protective effects against endothelia injury.This study determined whether resveratrol can reduce the palmitic acid (PA)-induced generation o reactive oxygen species (ROS)and further explored the underlying molecular mechanisms.We found tha resveratrol significantly reduced the PA-induced endothelial ROS levels in human aortic endothelial cells Resveratrol also induced endothelial cell autophagy,which mediated the effect of resveratrol on ROS reduction Resveratrol stimulated autophagy via the AMP-activated protein kinase (AMPK)-mTOR pathway.Taketogether,these data suggest that resveratrol prevents PA-induced intracellular ROS by autophagy regulation via the AMPK-mTOR pathway.Thus,the induction of autophagy by resveratrol may provide a novel therapeuti candidate for cardioprotection in metabolic syndrome. | Jun Song Yeping Huang Wenjian Zheng Jing Yan Min Cheng Ruxing Zhao Li Chen Cheng Hu Weiping Jia | 2018 | Frontiers of Medicine2018，12，6： | 7 |
| 7 | Sodium cantharidinate,a novel anti-pancreatic cancer agent that activates functional p53显示文摘Despite the use of many types of chemotherapies for pancreatic cancer, optimal efficacy has not been obtained so far. Pancreatic cancer shows a high incidence of TP53 mutations, inactivating its tumor suppressor activity. In this study, we identified sodium cantharidinate as a novel, potential anti-pancreatic cancer agent that activates p53 function. Sodium cantharidinate reduced the viability of pancreatic cancer cells, including the human primary pancreatic cancer cells, PANC-1, As PC-1, SW1990 and BXPC-3, in a dose-dependent manner. Sodium cantharidinate induced apoptosis and DNA damage of pancreatic cancer cells. Furthermore, proteome-wide sequencing analysis detected a marked perturbation in p53 signaling pathway on PANC-1 cells upon sodium cantharidinate. Consistent with the previous results, sodium cantharidinate treatment decreased Bcl-2 and mitochondrial cytochrome-c protein expression, as well as phosphorylation of MDM2;meanwhile, it increased the levels of cleaved-caspase-3,cleaved-caspase-9, cleaved-PARP, Bax, and phosphorylated p53, thus inducing the apoptosis of pancreatic cancer cells. The p53-activating effect of sodium cantharidinate was strongly abrogated by treatment with TP53-targeting sh RNA. Moreover, sodium cantharidinate inhibited neoplasm growth via the JAK2-STAT3 pathway, which was inhibited by sh RNA-TP53 and triggered by combination with gemcitabine. Combination therapy indicated that sodium cantharidinate and gemcitabine synergistically reduced ex vivo and in vivo growth of pancreatic neoplasm. Further docking studies revealed the different binding fates of sodium cantharidinate to activate wild-type p53 function. Thus, sodium cantharidinate could be a potential agent with promising anti-pancreatic cancer efficacy. | Xiaoxiao Liu Li Zhang Pyone Myat Thu Wenjian Min Peng Yang Ji Li Ping Li Xiaojun Xu | 2021 | Science China(Life Sciences)2021，64，8： | 5 |
| 8 | Pigment analysis of a color-leaf mutant in Wandering Jew (Tradescantia fluminensis) irradiated by carbon ions显示文摘Many mutants of plant induced by heavy ion beam irradiation have been reported in recent years,but leaf anthocyan mutants induced by ion irradiation in evergreen were rarely found.In this study,a color-leaf mutant with purple leaves,stems and petals was isolated from clones of Wandering Jew irradiated by 95.8 MeV/u carbon ion beam.The concentration and histological distribution of leaf pigment were surveyed in wild type and mutant.In mutant,contents of total chlorophylls (Chl),chlorophyll a (Chl a),chlorophyll b (Chl b) and carotenoids (Car) decreased significantly,while concentration of the anthocyanins was 6.2-fold higher than that of wild type.Further composition analysis of anthocyanins by electrospray ionization mass spectrometry (ESI-MS) indicated that the purple pigmentation of leaves in mutant was caused by accumulation of petunidin anthocyanin.Microscopic examination showed that most petunidin anthocyanin accumulated in the lower epidermis,and little in vascular parenchyma of mutant,while there was no pigment in wild type.Meanwhile,in spongy parenchyma of mutant we observed little Chl,which the wild type abounds in.In conclusion,the color-leaf mutant of Wandering Jew induced by irradiation of carbon ions was improved in ornamental value,and it could be contribute to variation in level,component and distribution of foliar pigment.The possible mutation mechanisms were discussed. | HE Jinyu LU Dong YU Lixia LI Wenjian | 2011 | Nuclear Science and Techniques2011，22，2： | 4 |
| 9 | Proximal development,systematic taxonomy,and dispersal pattern of the Early-Middle Ordovician graptolite Acrograptus from South China显示文摘Based on the well-preserved specimens from the Nanba section in Yiyang,Hunan Province,the definition of the graptolite genus Acrograptus is revised here.The revised Acrograptus is a dichograptid form with stipes subhorizontal to deeply declined,sicula long and slender;th1 1 budding from the top of the metasicula,proximal development of isograptid type with th1 2 as the dicalycal theca;asymmetric proximal end resulting from the divergence of th1 1 and th1 2 from the sicula at different levels;slender crossing canals composed of extremely slender prothecae of th1 1 and th1 2.According to the revised definition,Acrograptus is assigned to the subfamily Sigmagraptinae of the family Dichograptidae,including six species,i.e.,A.affinis (Nicholson),A.filiformis (Tullberg),A.gracilis (Trnquist),A.nicholsoni (Lapworth),A.pusillus (Tullberg),and A.saukros (Ni).During the Early-Middle Ordovician,these six species were widely distributed in South China,especially in the Upper Yangtze Region as well as the central and eastern Jiangnan Region.This study further indicates that Acrograptus first appeared in a deep-water setting on the Jiangnan Slope in South China during early Floian (Tetragraptus approximatus Biozone),and subsequently expanded into the shallow-water region on the Yangtze Platform due to a remarkable dispersion event in middle Floian (Pendeograptus fruticosus Biozone).It is here indicated that the dispersal of Acrograptus may be directly controlled by the large-scale transgression event occurring in middle Floian. | LI LiXia FENG HongZhen WANG WenHui CHEN WenJian | 2012 | Science China Earth Sciences2012，55，7： | 4 |
| 10 | Laminar shear stress delivers cell cycle arrest and anti-apoptosis to mesenchymal stem cells显示文摘Biomechanical 力量作为房间功能的批评管理者正在出现,液体流动是一个有势力机械刺激。尽管对液体作出回应的造骨细胞和 osteocytes 的机制流动被阐明,很少对怎么被知道 osteoprogenitors,间充质的干细胞(MSC ) ,对液体作出回应流动。这里,我们检验了 laminar 的效果砍在 vitro 的 MSC 上的应力(LSS ) 。从 SpragueDawley 老鼠的骨头髓的 MSC 被孤立,净化,并且使遭到了到 LSS 的生理的层次。DNA 合成和房间周期被测量通过[3H ] thymidine 并且由流动 cytometry,分别地检测细胞的增长。Annexin V immunostaining 和 Bcl-2/Bax mRNA 表示被评估在 MSC apoptosis 上决定 LSS 的效果。结果证明液体砍与房间的多数引起 MSC 的增长率的剂量相关的减小的应力在 G0 或 G1 阶段正在被逮捕。而且, LSS 的生理的层次在 MSC apoptosis 上施加了有势力抑制效果,这被发现。在摘要,这些数据在维持 MSC 的静止揭示了 LSS 的一个关键角色。 | Wei Luo Wei Xiong Jun Zhou Zhong Fang Wenjian Chen Yubo Fan Feng Li | 2011 | Acta Biochimica et Biophysica Sinica2011，43，3： | 4 |
| 11 | Intrinsically Stretchable Organic-Tribotronic-Transistor for Tactile Sensing显示文摘Stretchable electronics are of great significance for the development of the next-generation smart interactive systems.Here,we propose an intrinsically stretchable organic tribotronic transistor(SOTT)without a top gate electrode,which is composed of a stretchable substrate,silver nanowire electrodes,semiconductor blends,and a nonpolar elastomer dielectric.The drain-source current of the SOTT can be modulated by external contact electrification with the dielectric layer.Under 0-50%stretching both parallel and perpendicular to the channel directions,the SOTT retains great output performance.After being stretched to 50%for thousands of cycles,the SOTT can survive with excellent stability.Moreover,the SOTT can be conformably attached to the human hand,which can be used for tactile signal perception in human-machine interaction and for controlling smart home devices and robots.This work has realized a stretchable tribotronic transistor as the tactile sensor for smart interaction,which has extended the application of tribotronics in the human-machine interface,wearable electronics,and robotics. | Junqing Zhao Tianzhao Bu Xiaohan Zhang Yaokun Pang Wenjian Li Zhi Zhang Guoxu Liu Zhong Lin Wang Chi Zhang | 2020 | Research2020，，1： | 4 |
| 12 | Using Airgun Source Signals to Study Regional Wave Velocity Changes before and after the Yunlong M_S5.0 and Yangbi M_S5.1 Earthquakes显示文摘On the basis of the airgun source signals recorded by the stations from January,2016 to June,2017,we use cross-correlation detection technology to obtain the characteristics of the stable phase travel time change of each station.We used the Yunlong MS5.0 and Yangbi MS5.1 earthquakes as samples.According to regional characteristics,13 stations with high signal-to-noise ratios and complete data were selected(including 3 fixed stations and 10 active source stations).They are divided into four regions,and on the basis of the GNSS baseline data,the characteristics of regional wave velocity changes before and after the earthquake are analyzed.The results show that the station phase travel time change and the regional stress characteristics represented by the GNSS baseline data have good correlation in the short-term.Due to different degrees of regional stress,there are differences in the travel time changes of different stations in the four regions.Before the Yunlong MS5.0 and Yangbi MS5.1 earthquakes,with regional stress adjustment,there is an upward trend in the travel time changes of related stations in the adjacent areas of up to 0.02 s.The difference is that there are differences in the time nodes and duration of the travel time anomalies,and there is a reverse descent process after the Yangbi MS5.1 earthquake.There are different degrees of travel time fluctuations in the relevant stations before and after the two earthquakes,but the fluctuation range before and after the earthquake was small.Compared with the water level change of the reservoir,the adjustment of the regional stress is more likely to have a substantial impact on the travel time changes of the relevant stations. | YANG Jianwen LI Lei ZHANG Pengying YE Beng HE Yingwen CHEN Jia CHA Wenjian | 2019 | Earthquake Research in China2019，33，2： | 4 |
| 13 | Properties of coarse particles in suspended particulate matter of the North Yellow Sea during summer显示文摘Fine particles in seawater commonly form large porous aggregates. Aggregate density and settling velocity determine the behavior of this suspended particulate matter(SPM) within the water column.However, few studies of aggregate particles over a continental shelf have been undertaken. In our case study, properties of aggregate particles, including size and composition, over the continental shelf of the North Yellow Sea were investigated. During a scienti?c cruise in July 2016, in situ ef fective particle size distributions of SPM at 10 stations were measured, while temperature and turbidity measurements and samples of water were obtained from surface, middle, and bottom layers. Dispersed and inorganic particle size distributions were determined in the laboratory. The in situ SPM was divided into(1) small particles(<32 μm),(2) medium particles(32–256 μm) and(3) large particles(>256 μm). Large particles and medium particles dominated the total volume concentrations(VCs) of in situ SPM. After dispersion, the VCs of medium particles decreased to low values(<0.1 μL/L). The VCs of large particles in the surface and middle layers also decreased markedly, although they had higher peak values(0.1–1 μL/L). This suggests that almost all in situ medium particles and some large particles were aggregated, while other large particles were single particles. Correlation analysis showed that primary particles <32 μm in?uenced the formation of these aggregates. Microscopic examination revealed that these aggregates consisted of both organic and inorganic ?ne particles, while large particles were mucus-bound organic aggregates or individual plankton.The vertical distribution of coarser particles was clearly related to water strati?cation. Generally, medium aggregate particles were dominant in SPM of the bottom layer. A thermocline blocked resuspension of?ne material into upper layers, yielding low VCs of medium-sized aggregate particles in the surface layer.Abundant large biogenic particles were present in both surface and middle layers. | ZHANG Kainan WANG Zhenyan LI Wenjian YAN Jun | 2019 | Journal of Oceanology and Limnology2019，37，1： | 4 |
| 14 | Platelet-mediated adhesion facilitates leukocyte sequestration in hypoxia-reoxygenated microvessels显示文摘Leukocyte transendothelial migration and sequestration are two distinct outcomes following leukocyte adhesion to endothelium during ischemia-reperfusion injury, in which platelets may play a pivotal role. In the present study, we established an in vitro hypoxia-reoxygenation model to mimic ischemia-reperfusion injury and found platelet pre-incubation significantly increased leukocyte adhesion to endothelial cells after hyoxia-reoxygenation(over 67%). Blockade of endothelial-cell-expressed adhesion molecules inhibited leukocyte direct adhesion to endothelial cells, while platelet-mediated leukocyte adhesion was suppressed by blockade of platelet-expressed adhesion molecules. Further experiments revealed platelets acted as a bridge to mediate leukocyte adhesion, and platelet-mediated adhesion was the predominant pattern in the presence of platelets. However, platelet pre-incubation significantly suppressed leukocyte transendothelial migration after hypoxia-reoxygenation(over 31%), which could be aggravated by blockade of endothelial-cell-expressed adhesion molecules, but alleviated by blockade of platelet-expressed adhesion molecules. This would indicate that platelet-mediated adhesion disrupted leukocyte transendothelial migration. An in vivo mesenteric ischemia-reperfusion model demonstrated leukocyte transfusion alone caused mild leukocyte adhesion to reperfused vessels and subsequent leukocyte infiltration, while simultaneous leukocyte and platelet transfusion led to massive leukocyte adhesion and sequestration within reperfused microvessels. Our studies revealed platelets enhanced leukocyte adhesion to endothelial cells, but suppressed leukocyte transendothelial migration. Overall, this leads to leukocyte sequestration in hypoxia-reoxygenated microvessels. | Senfeng Zheng Yanting Cao Wenjian Zhang Honglin Liu Jia You Yiqing Yin Jinning Lou Chenghui Li | 2016 | Science China(Life Sciences)2016，59，3： | 3 |
| 15 | Systematically labeling developmental stage-specific genes for the study of pancreatic β-cell differentiation from human embryonic stem cells显示文摘 | Haisong Liu Huan Yang Dicong Zhu Xin Sui Juan Li Zhen Liang Lei Xu Zeyu Chen Anzhi Yao Long Zhang Xi Zhang Xing Yi Meng Liu Shiqing Xu Wenjian Zhang Hua Lin Lan Xie Jinning LOU Yong Zhang Jianzhong Xi Hongkui Deng | 2014 | Cell Research2014，24，10： | 3 |
| 16 | Calculation of depth-dose distribution of intermediate energy heavy-ion beams显示文摘Based on the characteristics of the interactions between intermediate energy heavy-ion beam and target matter, a method to calculate the depth-dose distribution of heavy-ion beams with intermediate energy (10-100 MeV/u) is presented. By comparing high energy beams where projectile fragmentation is overwhelming with low energies where energy straggling is the sole factor instead, a crescent energy spread with increasing depth and a simple fragmentation assumption were included for the depth-dose calculation of the intermediate energy beam. Relative depth-dose curves of carbon and oxygen ion beams with intermediate energies were computed according to the method here. Comparisons between the calculated relative doses and measurements are shown. The calculated Bragg curves, especially the upstream and downstream Bragg peaks, agree with the measured data. Differences between the two results appear only around the peak regions because of the limitations of the calculation and experimental conditions, but the | Qiang Li Zengquan Wei Wenjian Li | 2002 | Chinese Science Bulletin2002，47，20： | 3 |
| 17 | Uterine artery embolization in association with methotrexate infusion for the treatment of tubal ectopic pregnancy显示文摘Objective To investigate the safety, feasibility, and effectiveness of uterine artery embolization in association with methotrexate(MTX) infusion for the treatment of tubal ectopic pregnancy. Methods Fifty-one patients with tubal ectopic pregnancy were referred for interventional management. All patients received super-selective arteriography of the uterine artery, were infused with 50–100 mg methotrexate(MTX) through a catheter, and underwent embolization of the uterine artery with a gel-foam pledge. Clinical presentation, findings of physical examination, β-HCG values, and the size of the ectopic mass were documented for comparison. The concentration of MTX in blood was evaluated at 0.5, 6, 12, 24, 36, and 48 hours after the procedure. Results Forty-seven out of the 51 patients had clinical resolution of their tubal pregnancy(92.2%). The average time for the β-HCG value to decrease and come back to normal was 9.16 ± 2.54 days(mean +/-SD). MTX levels in peripheral blood could not be detected for patients who received 50 or 75 mg MTX at 36 hours after the procedure, while the MTX level was 0.01 μmol/L at 48 hours after the procedure for patients who received 100 mg. Out of the 4 cases whose ectopic mass size was ≥5 cm, 3 failed to respond to the treatment; however, those whose ectopic mass size was ≤5 cm responded positively to the treatment, regardless of the β-HCG concentration and abdominal bleeding, except for 1 patient who had to undergo laparoscopy for severe abdominal pain and who showed a reduction in her β-HCG level. Conclusion Uterine artery embolization in association with methotrexate infusion is safe and effective in the treatment of tubal ectopic pregnancy, especially for those women with mild to moderate bleeding, or for those at risk of a major hemorrhage. The selection criterion of mass size >5 cm should, therefore, be carefully considered. | Zhi Li Wenjian Xu Bo Hu Mingming Li Jianwei Zhou Caifang Ni | 2018 | Journal of Interventional Medicine2018，1，3： | 2 |
| 18 | Geochemistry and Petrogenesis of the ca. 2.5Ga High-K Granitoids in the Southern North China Craton显示文摘Archean high-K granitoids, generally formed after tonalite-trondhjemite-granodiorite (TTGs), are important for understanding crustal reworking of ancient cratons. The Linshan Archean high-K granitoids from the southern Trans-North China Orogen (TNCO) provide a window into the conti-nental crustal evolution of the North China Craton (NCC). They mainly consist of monzogranite and granodiorite which were formed during 2 542-2 503 Ma. The high-K granitoids have high SiO2 (65.86wt.%-78.08wt.%), K2O (3.29 wt.%-7.62wt.%) and low P2O5 (0.01 wt.%-0.27wt.%). They display right inclined REE patterns with negative Eu anomalies (Eu/Eu*=0.20-0.81).Their spider diagram is characterized by enrichment of Rb, K, Th, U and depletion of Nb, Ta, Zr, Ti. The rocks have positive and variable zircon εHf(t)(+2.5 to +6.6) and whole-rock εHf(t)(+0.7 to +4.5) with two-stage model ages (TDM2^Hf=2.87-2.64 Ga;TDM2^Nd=2.77-2.50 Ga) similar to those of the Archean TTG-ty pe rocks, amphibolites and diorites in the area. These evidences suggest that the high-K granitoids were produced by partial melting of juvenile crustal rocks. The Linshan high-K granitoids show relatively high whole-rock zircon saturation tempera-tures (694-889℃) and low Sr/Y ratios (0.27-21.1), indicating low pressure partial melting. Combined with other geological evidences, the Linshan high-K granitoids are suggested to have been produced by partial melting of the continental crust in a post-collision extensional environment after an arc-continent collision. Thus, the NCC did not amalgamate together until ca. 2.5 Ga. Compiled zircon U-Pb ages and Hf isotopes reveal that the ca. 2.5 Ga magmatism represents reworking of the continental crust. | Lei Li Wenjian Zhai | 2019 | Journal of Earth Science2019，30，3： | 2 |
| 19 | Surpassing electrocatalytic limit of earth-abundant Fe^(4+)embedded in N-doped graphene for(photo)electrocatalytic water oxidation显示文摘Developing highly active,cost-effective,and environmental friendly oxygen evolution reaction(OER)electrocatalysts facilitates various(photo)electrochemical processes.In this work,Fe3N nanoparticles encapsulated into N-doped graphene nanoshells(Fe_(3)N@NG)as OER electrocatalysts in alkaline media were reported.Both the experimental and theoretical comparison between Fe_(3) N@NG and Fe_(3)N/NG,specifically including in situ Mossbauer analyses,demonstrated that the NG nanoshells improved interfacial electron transfer process from Fe_(3)N to NG to form high-valence Fe^(4+)ions(Fe^(4+)@NG),thus modifying electronic properties of the outer NG shells and subsequently electron transfer from oxygen intermediate to NG nanoshells for OER catalytic process.Meanwhile,the NG nanoshells also protected Fe-based cores from forming OER inactive and insulated Fe_(2)O_(3),leading to high OER stability.As a result,the as-formed Fe^(4+)@NG shows one of the highest electrocatalytic efficiency among reported Fe-based OER electrocatalysts,which can as well highly improve the photoelectrochemical water oxidation when used as the cocatalysts for the Fe_(2)O_(3) nanoarray photoanode. | Wenjia Xue Feng Cheng Menglu Li Wenjian Hu Congping Wu Bing Wang Kuowei Liao ZhenTao Yu Yingfang Yao Wenjun Luo Zhigang Zou | 2021 | Journal of Energy Chemistry2021，30，3： | 2 |
| 20 | 3 - 43 Effects on Seedling Growth and Antioxidant Enzymes Activity of Oil-sunflower Irradiated by Carbon Ion Beams显示文摘 | Liu Qingfang Li Wenjian Qu Ying Zhou Libin Yu Lixia Du Yan | 2010 | IMP & HIRFL Annual Report2010，，1： | 2 |
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