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| 1 | Study on the photosynthetic performances of Enteromorpha prolifera collected from the surface and bottom of the sea of Qingdao sea area显示文摘In this work, the photosynthetic performances of Enteromorpha prolifera thalli collected from the sur- face and bottom of the sea of Qingdao sea area were studied with chlorophyll fluorescence and oxy- graph technology. The samples with the highest photosynthetic activity among their kinds, the floating thalli from the sea surface of the south of the Qingdao Olympic Sailing Center and the sedimentary thalli from the mud surface of the bottom Tuandao bay, were chosen as representatives of surface thalli and bottom thalli, respectively. The results showed that the maximal PSII quantum yield of the floating thalli was significantly lower than the normal level although their photosynthetic activities were relatively high; the photosynthetic potential of the thalli form the mud surface was extremely low. Thus, it is indicated that the floating thalli are seriously stressed by their environment and the thalli from the mud surface are already dead or are dying. On the other hand, the results of the laboratory cultivation showed that the sedimentary thalli cannot regain normal photosynthetic activity even under normal illumination condi- tions. Thus, the thalli from the mud surface cannot become reproductive source of the alga even if they can reach sea surface again. Therefore, a preliminary conclusion can be reached that, up to mid-July 2008, the environmental conditions of the Qingdao sea area are not suitable for the growth of the alga E. prolifera and for this reason the biomass of E. prolifera, in the area, could be declining. | LIN APeng WANG Chao QIAO HongJin PAN GuangHua WANG GuangCe SONG LiYun WANG ZhiYuan SUN Song ZHOU BaiCheng | 2009 | Chinese Science Bulletin2009，54，3： | 14 |
| 2 | Mantle upwelling beneath the South China Sea and links to surrounding subduction systems显示文摘The evolution of the South China Sea(SCS)is directly linked to the complex subduction systems of the surrounding Pacific,Philippine Sea and Indo-Australian Plates(Fig.1a).Major advances in the last several years are providing new insights into the SCSmantle dynamics,through regional seismic imaging of the upper mantle[1,2],unprecedented IODP drilling expeditions(349/367/368/368X)[3-5]that obtained the oceanic basement basalt samples for the first time,geochemical analyses of the SCS-mantle source compositions[6-8]and geodynamic modeling[9,10]. | Jian Lin Yigang Xu Zhen Sun Zhiyuan Zhou | 2019 | National Science Review2019，6，5： | 13 |
| 3 | Hypoxia induces PGC-la expression and mitochondrial biogenesis in the myocardium of TOF patients显示文摘 | Qiang Wang Lin Zhang Zhixiang Fang Fang Zhao Zhiyuan Lv Zuguang Gu Junfeng Zhang Jin Wang Ke Zen Yang Xiang Dongjin Wang Chen-Yu Zhang | 2010 | Cell Research2010，20，6： | 13 |
| 4 | Genetic and biological characteristics of the globally circulating H5N8 avian influenza viruses and the protective efficacy offered by the poultry vaccine currently used in China显示文摘The H5N8 avian influenza viruses have been widely circulating in wild birds and are responsible for the loss of over 33 million domestic poultry in Europe, Russia, Middle East, and Asia since January 2020. To monitor the invasion and spread of the H5N8 virus in China, we performed active surveillance by analyzing 317 wild bird samples and swab samples collected from 41,172 poultry all over the country. We isolated 22 H5N8 viruses from wild birds and 14 H5N8 viruses from waterfowls. Genetic analysis indicated that the 36 viruses formed two different genotypes: one genotype viruses were widely detected from different wild birds and domestic waterfowls;the other genotype was isolated from a whopper swan. We further revealed the origin and spatiotemporal spread of these two distinct H5N8 virus genotypes in 2020 and 2021. Animal studies indicated that the H5N8 isolates are highly pathogenic to chickens, mildly pathogenic in ducks, but have distinct pathotypes in mice. Moreover, we found that vaccinated poultry in China could be completely protected against H5N8 virus challenge. Given that the H5N8 viruses are likely to continue to spread in wild birds, vaccination of poultry is highly recommended in high-risk countries to prevent H5N8 avian influenza. | Pengfei Cui Xianying Zeng Xuyong Li Yanbing Li Jianzhong Shi Conghui Zhao Zhiyuan Qu Yanwen Wang Jing Guo Wenli Gu Qi Ma Yuancheng Zhang Weipeng Lin Minghui Li Jingman Tian Dongxue Wang Xin Xing Yanjing Liu Shuxin Pan Yaping Zhang Hongmei Bao Liling Liu Guobin Tian Chengjun Li Guohua Deng Hualan Chen | 2022 | Science China(Life Sciences)2022，65，4： | 12 |
| 5 | Improved Brassica rapa reference genome by single-molecule sequencing and chromosome conformation capture technologies显示文摘Brassica rapa comprises several important cultivated vegetables and oil crops.Current reference genome assemblies of Brassica rapa are quite fragmented and not highly contiguous,thereby limiting extensive genetic and genomic analyses.Here,we report an improved assembly of the B.rapa genome(v3.0)using single-molecule sequencing,optical mapping,and chromosome conformation capture technologies(Hi-C).Relative to the previous reference genomes,our assembly features a contig N50 size of 1.45 Mb,representing a~30-fold improvement.We also identified a new event that occurred in the B.rapa genome~1.2 million years ago,when a long terminal repeat retrotransposon(LTR-RT)expanded.Further analysis refined the relationship of genome blocks and accurately located the centromeres in the B.rapa genome.The B.rapa genome v3.0 will serve as an important community resource for future genetic and genomic studies in B.rapa.This resource will facilitate breeding efforts in B.rapa,as well as comparative genomic analysis with other Brassica species. | Lei Zhang Xu Cai Jian Wu Min Liu Stefan Grob Feng Cheng Jianli Liang Chengcheng Cai Zhiyuan Liu Bo Liu Fan Wang Song Li Fuyan Liu Xuming Li Lin Cheng Wencai Yang Mai-he Li Ueli Grossniklaus Hongkun Zheng Xiaowu Wang | 2018 | Horticulture Research2018，5，1： | 10 |
| 6 | Simultaneous incorporation of PTH(1-34) and nano-hydroxyapatite into Chitosan/Alginate Hydrogels for efficient bone regeneration显示文摘Tissue regeneration based on the utilization of artificial soft materials is considered a promising treatment for bone-related diseases.Here,we report cranial bone regeneration promoted by hydrogels that contain parathyroid hormone(PTH)peptide PTH(1-34)and nano-hydroxyapatite(nHAP).A combination of the positively charged natural polymer chitosan(CS)and negatively charged sodium alginate led to the formation of hydrogels with porous structures,as shown by scanning electron microscopy.Rheological characterizations revealed that the mechanical properties of the hydrogels were almost maintained upon the addition of nHAP and PTH(1-34).In vitro experiments showed that the hydrogel containing nHAP and PTH(1-34)exhibited strong biocompatibility and facilitated osteogenic differentiation of rat bone marrow mesenchymal stem cells(rBMSCs)via the Notch signaling pathway,as shown by the upregulated expression of osteogenic-related proteins.We found that increasing the content of PTH(1-34)in the hydrogels resulted in enhanced osteogenic differentiation of BMSCs.Implantation of the complex hydrogel into a rat cranial defect model led to efficient bone regeneration compared to the rats treated with the hydrogel alone or with nHAP,indicating the simultaneous therapeutic effect of nHAP and PTH during the treatment process.Both the in vitro and in vivo results demonstrated that simultaneously incorporating nHAP and PTH into hydrogels shows promise for bone regeneration,suggesting a new strategy for tissue engineering and regeneration in the future. | Zhiyuan Zou Le Wang Zhifei Zhou Qing Sun Delong Liu Yan Chen Hao Hu Yu Cai Sixiong Lin Zhengran Yu Bizhi Tan Wei Guo Zemin Ling Xuenong Zou | 2021 | Bioactive Materials2021，6，6： | 7 |
| 7 | RBMDO Using Gaussian Mixture Model-Based Second-Order Mean-Value Saddlepoint Approximation显示文摘Actual engineering systems will be inevitably affected by uncertain factors.Thus,the Reliability-Based Multidisciplinary Design Optimization(RBMDO)has become a hotspot for recent research and application in complex engineering system design.The Second-Order/First-Order Mean-Value Saddlepoint Approximate(SOMVSA/-FOMVSA)are two popular reliability analysis strategies that are widely used in RBMDO.However,the SOMVSA method can only be used efficiently when the distribution of input variables is Gaussian distribution,which significantly limits its application.In this study,the Gaussian Mixture Model-based Second-Order Mean-Value Saddlepoint Approximation(GMM-SOMVSA)is introduced to tackle above problem.It is integrated with the Collaborative Optimization(CO)method to solve RBMDO problems.Furthermore,the formula and procedure of RBMDO using GMM-SOMVSA-Based CO(GMM-SOMVSA-CO)are proposed.Finally,an engineering example is given to show the application of the GMM-SOMVSA-CO method. | Debiao Meng Shiyuan Yang Tao Lin Jiapeng Wang Hengfei Yang Zhiyuan Lv | 2022 | Computer Modeling in Engineering & Sciences2022，，8： | 6 |
| 8 | Modeling of normal faulting in the subducting plates of the Tonga,Japan,Izu-Bonin and Mariana Trenches:implications for near-trench plate weakening显示文摘The plate flexure and normal faulting characteristics along the Tonga, Japan, Izu-Bonin and Mariana Trenches are investigated by combining observations and modeling of elastoplastic deformation of the subducting plate. The observed average trench relief is found to be the smallest at the Japan Trench(3 km) and the largest at the Mariana Trench(4.9 km), and the average fault throw is the smallest at the Japan Trench(113 m) and the largest at the Tonga Trench(284 m). A subducting plate is modeled to bend and generate normal faults subjected to three types of tectonic loading at the trench axis: vertical loading, bending moment, and horizontal tensional force. It is inverted for the solutions of tectonic loading that best fit the observed plate flexure and normal faulting characteristics of the four trenches. The results reveal that a horizontal tensional force(HTF) for the Japan Trench is 33%, 50% and 60% smaller than those of the Mariana, Tonga and Izu-Bonin Trenches, respectively. The normal faults are modeled to penetrate to a maximum depth of 29, 23, 32 and 32 km below the sea floor for the Tonga,Japan, Izu-Bonin and Mariana Trenches, respectively, which is consistent with the depths of relocated normal faulting earthquakes in the Japan and Izu-Bonin Trenches. Moreover, it is argued that the calculated horizontal tensional force is generally positively correlated with the observed mean fault throw, while the integrated area of the reduction in the effective elastic thickness is correlated with the trench relief. These results imply that the HTF plays a key role in controlling the normal faulting pattern and that plate weakening can lead to significant increase in the trench relief. | ZHOU Zhiyuan LIN Jian ZHANG Fan | 2018 | Acta Oceanologica Sinica2018，37，11： | 4 |
| 9 | Charge‑Transfer Resonance and Electromagnetic Enhancement Synergistically Enabling MXenes with Excellent SERS Sensitivity for SARS‑CoV‑2 S Protein Detection显示文摘The outbreak of coronavirus disease 2019 has seriously threatened human health.Rapidly and sensitively detecting SARSCoV-2 viruses can help control the spread of viruses.However,it is an arduous challenge to apply semiconductor-based substrates for virus SERS detection due to their poor sensitivity.Therefore,it is worthwhile to search novel semiconductor-based substrates with excellent SERS sensitivity.Herein we report,for the first time,Nb2C and Ta2C MXenes exhibit a remarkable SERS enhancement,which is synergistically enabled by the charge transfer resonance enhancement and electromagnetic enhancement.Their SERS sensitivity is optimized to 3.0×10^6 and 1.4×10^6 under the optimal resonance excitation wavelength of 532 nm.Additionally,remarkable SERS sensitivity endows Ta2C MXenes with capability to sensitively detect and accurately identify the SARS-CoV-2 spike protein.Moreover,its detection limit is as low as 5×10^−9 M,which is beneficial to achieve real-time monitoring and early warning of novel coronavirus.This research not only provides helpful theoretical guidance for exploring other novel SERS-active semiconductor-based materials but also provides a potential candidate for the practical applications of SERS technology. | Yusi Peng Chenglong Lin Li Long Tanemura Masaki Mao Tang Lili Yang Jianjun Liu Zhengren Huang Zhiyuan Li Xiaoying Luo John RLombardi Yong Yang | 2021 | Nano-Micro Letters2021，13，3： | 3 |
| 10 | Pole-to-ground Fault Analysis for HVDC Grid Based on Common-and Differential-mode Transformation显示文摘Pole-to-ground(PTG) fault analysis is of vital importance for high-voltage direct current(HVDC) grid. However, many factors are not considered in the existing studies such as the asymmetrical property of PTG fault, the coupling issue between DC transmission lines and the complexity of the structure of DC grid. This paper presents a PTG fault analysis method, which is based on common-and differential-mode(CDM)transformation. Similar to the symmetrical component method in AC system, the transformation decomposes the HVDC grid into CDM networks, which is balanced and decoupled. Then, a transfer impedance is defined and calculated based on the impedance matrices of the CDM networks. With the transfer impedance, analytical expressions of fault characteristics that vary with space and time are obtained. The proposed PTG fault analysis method is applicable to arbitrary HVDC grid topologies,and provides a new perspective to understand the fault mechanism. Moreover, the analytical expressions offer theoretical guidance for PTG fault protection. The validity of the proposed PTG fault analysis method is verified in comparison with the simulation results in PSCAD/EMTDC. | Zhen He Jiabing Hu Lei Lin Yuanzhu Chang Zhiyuan He | 2020 | Journal of Modern Power Systems and Clean Energy2020，8，3： | 3 |
| 11 | Utilization and quality assessment of digestive endoscopy in China:results from 5-year consecutive nationwide surveys显示文摘Background:Worldwide,the volume and availability of digestive endoscopy have undergone dramatic development in recent years,with increasing attention on quality assurance.We investigated the utilization and quality of digestive endoscopy in China from 2015 to 2019 and developed a quantitative quality evaluation tool for medical institutions.Methods:We invited all tertiary/secondary hospitals in Chinese mainland to participate in the survey annually.The questionnaires included the personnel,annual volume,and quality indicators of endoscopy.An endoscopy quality index(EQI)was developed based on recorded quality indicators using principal component analysis to determine the relative weight.Results:From 2015 to 2019,806,1412,2644,2468,and 2541 hospitals were respectively enrolled in this study.The average annual volume of endoscopy increased from 12,445 to 16,206(1.30-fold)and from 2938 to 4255(1.45-fold)in tertiary and secondary hospitals,respectively.The most obvious growth was observed in diagnostic colonoscopy(1.44-fold for all hospitals after standardization).The proportion of early cancer among all esophageal and gastric cancers during diagnostic esophagogastroduodenoscopy increased from 12.3%(55,210/448,861)to 17.7%(85,429/482,647)and from 11.4%(69,411/608,866)to 16.9%(107,192/634,235),respectively.The adenoma detection rate of diagnostic colonoscopy increased from 14.9%(2,118,123/14,215,592)to 19.3%(3,943,203/20,431,104).The EQI model included 12 quality indicators,incorporating 64.9%(7.792/12)of the total variance into one comprehensive index.According to the EQI measurements,the quality of endoscopy was higher in tertiary hospitals and hospitals in developed areas with higher volume or more endoscopists than that in other hospitals.Conclusions:Digestive endoscopy in China has developed considerably in recent years in terms of both volume and quality.The EQI is a promising tool to quantify the quality of endoscopy at different hospitals. | Lei Xin Ye Gao Zhiyuan Cheng Tianjiao Wang Han Lin Yanan Pang Chang Sun Zengjun Fu Zhaoshen Li Xudong Ma Luowei Wang | 2022 | Chinese Medical Journal2022，135，16： | 3 |
| 12 | Phase calibration for integrated optical phased arrays using artificial neural network with resolved phase ambiguity显示文摘Phase calibration for optical phased arrays(OPAs) is a key process to compensate for the phase deviation and retrieve the initial working state. Conventional calibration approaches based on iterative optimization algorithms are tedious and time-consuming. The essential difficulty of such a problem is to inversely solve for the phase error distribution among OPA elements from the far-field pattern of an OPA. Deep-learning-based technology might offer an alternative approach without explicitly knowing the inverse solution. However, we find that the phase ambiguities, including conjugate ambiguity and periodic ambiguity, severely deter the accuracy and efficacy of deep-learning-based calibration. Device-physics-based analysis reveals the causes of the phase ambiguities, which can be resolved by creating a tailored artificial neural network with phase-masked far-field patterns in a conjugate pair and constructing a periodic continuity-preserving loss function. Through the ambiguity-resolved neural network, we can extract phase error distribution in an OPA and calibrate the device in a rapid, noniterative manner from the measured far-field patterns. The proposed approach is experimentally verified. Pure main-beam profiles with >12 dB sidelobe suppression ratios are observed. This approach can help overcome a crucial bottleneck for the further advance of OPAs in a variety of applications such as lidar. | Lemeng Leng Zhaobang Zeng Guihan Wu Zhongzhi Lin Xiang Ji Zhiyuan Shi Wei Jiang | 2022 | Photonics Research2022，10，2： | 3 |
| 13 | Interface science in polymer-based composite solid electrolytes in lithium metal batteries显示文摘Solid-state lithium metal batteries(SSLMBs)have attracted considerable attention as one of the most promising energy storage systems owing to their high safety and energy density.Solid electrolytes,particularly polymer-based composite solid electrolytes(CSEs),are considered promising electrolyte candidates for SSLMBs.However,theirwide application is inhibited by various electrochemical issues,such as low ionic conductivity,the growth of lithium dendrites,and poor cycling stability,which are related to interface issues within SSLMBs.In this review,the parameters related to various interfaces in the CSE of SSLMBs,including the interfaces between the polymer matrix and inorganic fillers,between the CSEs and the cathode,and between the CSEs and the lithium metal anode,are examined.Relevant issues and corresponding remediation strategies are proposed.Finally,future perspectives based on interfacial engineering and the characterization of polymer/inorganic filler interactions are proposed for building high-performance CSEs for use in SSLMBs. | Lingqiao Wu Yongtao Wang Xianwei Guo Peipei Ding Zhiyuan Lin Haijun Yu | 2022 | SusMat2022，2，3： | 2 |
| 14 | Genetic dissection of tetraploid cotton resistant to Verticillium wilt using interspecific chromosome segment introgression lines显示文摘Verticillium wilt(caused by the pathogen Verticillium dahliae) is of high concern for cotton producers and consumers. The major strategy for controlling this disease is the development of resistant cotton(Gossypium spp.) cultivars. We used interspecific chromosome segment introgression lines(CSILs) to identify quantitative trait loci(QTL) associated with resistance to Verticillium wilt in cotton grown in greenhouse and inoculated with three defoliating V. dahliae isolates. A total of 42 QTL, including 23 with resistance-increasing and 19 with resistancedecreasing, influenced host resistance against the three isolates. These QTL were identified and mapped on 18 chromosomes(chromosomes A1, A3, A4, A5, A7, A8, A9, A12, A13, D1, D2,D3, D4, D5, D7, D8, D11, and D12), with LOD values ranging from 3.00 to 9.29. Among the positive QTL with resistance-increasing effect, 21 conferred resistance to only one V. dahliae isolate, suggesting that resistance to V. dahliae conferred by most QTL is pathogen isolate-specific. The At subgenome of cotton had greater effect on resistance to Verticillium wilt than the Dt subgenome. We conclude that pyramiding different resistant QTL could be used to breed cotton cultivars with broad-spectrum resistance to Verticillium wilt. | Peng Wang Zhiyuan Ning Ling Lin Hong Chen Hongxian Mei Jun Zhao Bingliang Liu Xin Zhang Wangzhen Guo Tianzhen Zhang | 2014 | The Crop Journal2014，2，5： | 2 |
| 15 | Dynamical Stability of Cantilevered Pipe Conveying Fluid with Inerter-Based Dynamic Vibration Absorber显示文摘Cantilevered pipe conveying fluid may become unstable and flutter instability would occur when the velocity of the fluid flow in the pipe exceeds a critical value.In the present study,the theoretical model of a cantilevered fluid-conveying pipe attached by an inerter-based dynamic vibration absorber(IDVA)is proposed and the stability of this dynamical system is explored.Based on linear governing equations of the pipe and the IDVA,the effects of damping coefficient,weight,inerter,location and spring stiffness of the IDVAon the critical flow velocities of the pipe system is examined.It is shown that the stability of the pipe may be significantly affected by the IDVA.In many cases,the stability of the cantilevered pipe can be enhanced by designing the parameter values of the IDVA.By solving nonlinear governing equations of the dynamical system,the nonlinear oscillations of the pipe with IDVA for sufficiently high flow velocity beyond the critical value are determined,showing that the oscillation amplitudes of the pipe can also be suppressed to some extent with a suitable design of the IDVA. | Zhiyuan Liu Xin Tan Xiaobo Liu Pingan Chen Ke Yi Tianzhi Yang Qiao Ni Lin Wang | 2020 | Computer Modeling in Engineering & Sciences2020，，11： | 2 |
| 16 | FOXP3 and RORγt: Transcriptional regulation of Treg and Th17显示文摘 | Zuojia Chen Fang Lin Yayi Gao Zhiyuan Li Jing Zhang Yue Xing Zihou Deng Zhengju Yao Andy Tsun Bin Li | 2010 | International Immunopharmacology2010，，5： | 2 |
| 17 | Nuciferine protects against high-fat diet-induced hepatic steatosis and insulin resistance via activating TFEB-mediated autophagy——lysosomal pathway显示文摘Nonalcoholic fatty liver disease(NAFLD) is characterized by hepatic steatosis and insulin resistance and there are currently no approved drugs for its treatment.Hyperactivation of mTOR complex1(mTORCl) and subsequent impairment of the transcription factor EB(TFEB)-mediated autophagy-lysosomal pathway(ALP) are implicated in the development of NAFLD.Accordingly,agents that augment hepatic TFEB transcriptional activity may have therapeutic potential against NAFLD.The objective of this study was to investigate the effects of nuciferine,a major active component from lotus leaf,on NAFLD and its underlying mechanism of action.Here we show that nuciferine activated ALP and alleviated steatosis,insulin resistance in the livers of NAFLD mice and palmitic acid-challenged hepatocytes in a TFEB-dependent manner.Mechanistic investigation revealed that nuciferine interacts with the Ragulator subunit hepatitis B X-interacting protein and impairs the interaction of the Ragulator complex with Rag GTPases,thereby suppressing lysosomal localization and activity of mTORC1,which activates TFEB-mediated ALP and further ameliorates hepatic steatosis and insulin resistance.Our present results indicate that nuciferine may be a potential agent for treating NAFLD and that regulation of the mTORCl-TFEB-ALP axis could represent a novel pharmacological strategy to combat NAFLD. | Xiliang Du Chiara Di Malta Zhiyuan Fang Taiyu Shen Xiaodi Niu Meng Chen Bo Jin Hao Yu Lin Lei Wenwen Gao Yuxiang Song Zhe Wang Chuang Xu Zhijun Cao Guowen Liu Xinwei Li | 2022 | Acta Pharmaceutica Sinica B2022，12，6： | 2 |
| 18 | Synthesis and High Electrocatalytic Performance of Hexagram Shaped Gold Particles Having an Open Surface Structure with Kinks显示文摘塑造的金粒子和他们的类似物与性变态由高索引方面围住的六芒星形被与维生素酸(AA ) 减少 HAuCl4 面对成功地综合了 poly (diallyldimethylammonium 氯化物) 在房间温度。由使用电子显微镜学,塑造的 Au 粒子被发现是的六芒星形的表面 { 541 } 飞机,它包含高密度的步和性变态。另外,它被发现那六角形像盾并且在产品在场的其它种粒子是塑造的 Au 粒子组织的六芒星形的类似物,在那,他们有一样的表面结构。以便证实所有准备粒子的表面结构,表面结构 Pb 的敏感 underpotential 免职被执行,并且周期的 voltammetric 侧面根据求婚 { 541 } 表面。最后, Au 六芒星形的结构性质关系被作为探查反应采用 AA 的 electrocatalytic 氧化试验性地分析。金立方体与的 electrocatalytic 反应低索引 { 100 } 方面和金 trioctahedra 与 { 221 } 方面作为参考书被学习。试验性的结果证明六芒星形塑造了 Au 粒子和他们的类似物与暴露 { 541 } 方面在三种金粒子之中举办最高催化的活动,由于纽结原子的高密度。这研究应该激发我们进一步为高索引表面围住的另外的明确的多面的金属 nanocrystals 的准备探索方法。 | Qingning Jiang Zhiyuan Jiang Lei Zhang Haixin Lin Ning Yang Huan Li Deyu Liu Zhaoxiong Xie Zhongqun Tian | 2011 | Nano Research2011，4，6： | 2 |
| 19 | Photonic crystal cavities and integrated optical devices显示文摘This paper gives a brief introduction to our recent works on photonic crystal(Ph C) cavities and related integrated optical structures and devices. Theoretical background and numerical methods for simulation of Ph C cavities are first presented. Based on the theoretical basis, two relevant quantities, the cavity mode volume and the quality factor are discussed. Then the methods of fabrication and characterization of silicon Ph C slab cavities are introduced. Several types of Ph C cavities are presented, such as the usual L3 missing-hole cavity, the new concept waveguide-like parallel-hetero cavity, and the low-index nanobeam cavity. The advantages and disadvantages of each type of cavity are discussed. This will help the readers to decide which type of Ph C cavities to use in particular applications. Furthermore, several integrated optical devices based on Ph C cavities, such as optical filters, channel-drop filters, optical switches, and optical logic gates are described in both the working principle and operation characteristics. These devices designed and realized in our group demonstrate the wide range of applications of Ph C cavities and offer possible solutions to some integrated optical problems. | GAN Lin LI ZhiYuan | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，11： | 2 |
| 20 | The chimeric gene atp6c confers cytoplasmic male sterility in maize by impairing the assembly of the mitochondrial ATP synthase complex显示文摘Cytoplasmic male sterility(CMS)is a powerful tool for the exploitation of hybrid heterosis and the study of signaling and interactions between the nucleus and the cytoplasm.C-type CMS(CMS-C)in maize has long been used in hybrid seed production,but the underlying sterility factor and its mechanism of action remain unclear.In this study,we demonstrate that the mitochondrial gene atp6c confers male sterility in CMS-C maize.The ATP6C protein shows stronger interactions with ATP8 and ATP9 than ATP6 during the assembly of F1F0-ATP synthase(F-type ATP synthase,ATPase),thereby reducing the quantity and activity of assem-bled F_(1)F_(o)-ATP synthase.By contrast,the quantity and activity of the F1'component are increased in CMS-C lines.Reduced F1F0-ATP synthase activity causes accumulation of excess protons in the inner membrane space of the mitochondria,triggering a burst of reactive oxygen species(ROS),premature programmed cell death of the tapetai cells,and pollen abortion.Collectively,our study identifies a chimeric mitochondrial gene(ATP6C)that causes CMS in maize and documents the contribution of ATP6C to F1F0-ATP synthase assembly,thereby providing novel insights into the molecular mechanisms of male sterility in plants. | Huili Yang Yadong Xue Bing Li Yanan Lin Haochuan Li Zhanyong Guo Weihua Li Zhiyuan Fu Dong Ding Jihua Tang | 2022 | Molecular Plant2022，15，5： | 2 |
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