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| 1 | Chemical composition of PM_(2.5) during winter in Tianjin,China显示文摘PM2.5 samples for 24 h were collected during winter in Tianjin,China. The ambient mass concentration and chemical composition of the PM2.5 were determined. Ionic species were analyzed by ion chromatog-raphy,while carbonaceous species were determined with the IMPROVE thermal optical reectance(TOR) method,and inorganic elements were measured by inductively coupled plasma-atomic emission spec-trometer. The daily PM2.5 mass concentrations ranged from 48.2 to 319.2 g/m3 with an arithmetic average of 144.6 g/m3. The elevated PM2.5 in winter was mostly attributed to combustion sources such as vehicle exhaust,heating,cooking and industrial emissions,low wind speeds and high relative humidity(RH) ,which were favorable for pollutant accumulation and formation of secondary pollutants. By chem-ical mass balance,it was estimated that about 89.1% of the PM2.5 mass concentrations were explained by carbonaceous species,secondary particles,crustal matters,sea salt and trace elements. Organic material was the largest contributor,accounting for about 32.7% of the total PM2.5 mass concentrations. SO42-,NO3-,Cl- and NH4+ were four major ions,accounting for 16.6%,11.5%,4.7% and 6.0%,respectively,of the total mass of PM2.5. | Jinxia Gu Zhipeng Bai Weifang Li Liping Wu Aixia Liu Haiyan Dong Yiyang Xie | 2011 | Particuology2011，9，3： | 60 |
| 2 | A land use regression for predicting NO_2 and PM_(10) concentrations in different seasons in Tianjin region,China显示文摘Land use regression (LUR) model was employed to predict the spatial concentration distribution of NO2 and PM10 in the Tianjin region based on the environmental air quality monitoring data. Four multiple linear regression (MLR) equations were established based on the most significant variables for NO2 in heating season (R2 = 0.74), and non-heating season (R2 = 0.61) in the whole study area; and PM10 in heating season (R2 = 0.72), and non-heating season (R2 = 0.49). Maps of spatial concentration distribution for NO2 and PM10 were obtained based on the MLR equations (resolution is 10 km). Intercepts of MLR equations were 0.050 (NO2, heating season), 0.035 (NO2, non-heating season), 0.068 (PM10, heating season), and 0.092 (PM10, non-heating season) in the whole study area. In the central area of Tianjin region, the intercepts were 0.042 (NO2, heating season), 0.043 (NO2, non-heating season), 0.087 (PM10, heating season), and 0.096 (PM10, non-heating season). These intercept values might imply an area’s background concentrations. Predicted result derived from LUR model in the central area was better than that in the whole study area. R2 values increased 0.09 (heating season) and 0.18 (non-heating season) for NO2, and 0.08 (heating season) and 0.04 (non-heating season) for PM10. In terms of R2, LUR model performed more effectively in heating season than non-heating season in the study area and gave a better result for NO2 compared with PM10. | Li Chen Zhipeng Bai Shaofei Kong Bin Han Yan You Xiao Ding Shiyong Du Aixia Liu | 2010 | Journal of Environmental Sciences2010，22，9： | 12 |
| 3 | Land cover mapping using time series HJ-1 / CCD data显示文摘It is very difficult to have remote sensing data with both high spatial resolution and high temporal frequency; thus, two categories of land-use mapping methodology have been developed separately for coarser resolution and finer resolution data. The first category uses time series of data to retrieve the variation of land surface for classification, which are usually used for coarser resolution data with high temporal frequency. The second category uses fine spatial resolution data to classify different land surface. With the launch of Chinese satellite constellation HJ-1in 2008, four 30 m spatial resolution CCDs with about 360 km coverage for each one onboard two satellites made a revisit period of two days, which brought a new type of data with both high spatial resolution and high temporal frequency. Therefore, by taking the spatiotemporal advantage of HJ-1/CCD data we propose a new method for finer resolution land cover mapping using the time series HJ-1/CCD data, which can greatly improve the land cover mapping accuracy. In our two study areas, the very high resolution remote sensing data within Google Earth are used to validate the land cover mapping results, which shows a very high mapping accuracy of 95.76% and 83.78% and a high Kappa coefficient of 0.9423 and 0.8165 in the Dahuofang area of Liaoning Province and the Heiquan area of Gansu Province respectively. | ZHONG Bo MA Peng NIE AiHua YANG AiXia YAO YanJuan Lü WenBo ZHANG Hang LIU QinHuo | 2014 | Science China Earth Sciences2014，57，8： | 9 |
| 4 | Triglycerides and ratio of triglycerides to high-density lipoprotein cholesterol are better than liver enzymes to identify insulin resistance in urban middle-aged and older non-obese Chinese without diabetes显示文摘 | Sun Yu Li Wenjuan Hou Xinguo Wang Chuan Li Chengqiao Zhang Xiuping Yang Weifang Ma Zeqiang Wang Weiqing Ning Guang Zheng Huizhen Ma Aixia Song Jun Lin Peng Liang Kai Liu Fuqiang Gong Lei Wang Meijian Xiao Juan Yan Fei Yang Junpeng Wang Lingshu Tian Meng Liu Jidong Zhao Ruxing Zhu Ping Chen Li | 2014 | Chinese Medical Journal2014，，10： | 7 |
| 5 | Circadian clock gene expression regulates cancer cell growth through glutaminase显示文摘夫酸安是为恶意的肿瘤房间的必要氨基酸。使夫酸安产生代射变化的 Glutaminase 到达肿瘤立即在最大的增长前评估的最大的 expressionin。肿瘤房间在日子期间以不同的率成长。我们 postulatedthat 在肿瘤房间的 glutaminase 的活动服从于生理节奏的钟基因的规定。我们测量了由在在六 equispaced 时间的肝和 tumorcells 的即时聚合酶链反应的西方的污点分析和生理节奏的钟基因表示削尖的 glutaminaseby 在一张 12/12 h 光 / 黑暗时间表的单个鼠标今日。结果显示出 thatthe 忍受肿瘤的鼠标,在正常下面日报条件,生理节奏地被乘火车,由正常主机 locomotoractivity 节奏和有韵律的肝钟基因表示思考了。在这些老鼠以内的肿瘤生理节奏地也被组织,由生理节奏的钟基因(Bmal1 ) 的 asreflected 表示。是很显著的的,是肾类型 glutaminase 也在一样的模式 withtumor 显示出生理节奏的节奏在肝癌症异种皮移植模型的生理节奏的钟基因表示,有条件地显示那禁止 glutaminaseactivity 可以为癌症提供一个新目标治疗。 | Aixia Huang Bingbo Bao H Rex Gaskins Haijun Liu Xueli Zhang Liwen Lu Shan Gao Yihai Shi Ming Zhang Yuanzhou Shan Jing Feng Guoxiang Yao | 2014 | Acta Biochimica et Biophysica Sinica2014，46，5： | 3 |
| 6 | Implementing two optimal economical quantum cloning with superconducting quantum interference devices in a cavity显示文摘We propose a unified scheme to implement the optimal 1→ 3economical phase-covariant quantum cloning and optimal 1→3 economical real state cloning with superconducting quantum interference devices (SQUIDs) in a cavity.During this process,no transfer of quantum information between the SQUIDs and cavity is required.The cavity field is only virtually excited.The scheme is insensitive to cavity decay.Therefore,the scheme can be experimentally realized in the range of current cavity QED techniques. | YE Liu HU GuiYu LI AiXia | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，1： | 3 |
| 7 | Reactive oxygen species regulate auxin levels to mediate adventitious root induction in Arabidopsis hypocotyl cuttings显示文摘Adventitious root(AR)formation from leafy stem cuttings is critical for breeding of many forest and horticultural species.In addition to the plant hormone auxin,wound-induced signaling caused by the cutting excision is also essential for AR initiation.Here we found that reactive oxygen species(ROS)are rapidly generated at the excision site as a wound-induced signal and propagated throughout the hypocotyl cut-ting after excision of the Arabidopsis(Arabidopsis thaliana)primary root.ROS propagation was not ob-served in the presence of an NADPH oxidase inhibitor(diphenylene iodonium chloride)or in a knockout mu-tant of the NADPH oxidase gene respiratory burst oxi-dase homolog protein D(RBOHD).Respiratory burst oxidase homolog protein D was specifically upregulatedin hypocotyl cuttings at 0.5 h post excision(hpe).To-gether,these data suggest that RBOHD mediates ROS propagation in hypocotyl cuttings.We also found that auxin levels increased significantly in the shoot apex at 5 hpe and at the base of the cutting at 6 hpe;these effects were blocked by treatment with ROS scav-engers.Consistent with this,transcript levels of auxin biosynthesis and polar-transport genes generally in-creased between 1 to 6 hpe.Collectively,our results suggest that wound-induced ROS participate in AR in-duction through regulation of auxin biosynthesis and transport. | Aixia Huang Yongshun Wang Yangyang Liu Guodong Wang Xiaoping She | 2020 | Journal of Integrative Plant Biology2020，62，7： | 3 |
| 8 | Genomic footprints of Kam Sweet Rice domestication indicate possible migration routes of theDongpeople inChina andprovide resources for future rice breeding显示文摘The Dong people are one of China’s 55 recognized ethnic minorities,but there has been a long-standing debate about their origins.In this study,we performed whole-genome resequencing of Kam Sweet Rice(KSR),a valuable,rare,and ancient rice landrace unique to the Dong people.Through comparative genomic analyses of KSR and other rice landraces from south of the Yangtze River Basin in China,we provide evidence that the ancestors of the Dong people likely originated from the southeast coast of China at least 1000 years ago.Alien introgression and admixture in KSR demonstrated multiple migration events in the history of the Dong people.Genomic footprints of domestication demonstrated characteristics of KSR that arose from artificial selection and geographical adaptation by the Dong people.The key genes GS3,Hd1,and DPS1(related to agronomic traits)and LTG1 and MYBS3(related to cold tolerance)were identified as domestication targets,reflecting crop improvement and changes in the geographical environment of the Dong people during migration.A genome-wide association study revealed a candidate yield-associated gene,Os01g0923300,a specific haplotype in KSR that is important for regulating grain number per panicle.RNA-sequencing and quantitative reverse transcription-PCR results showed that this gene was more highly expressed in KSR than in ancestral populations,indicating that it may have great value in increasing yield potential in other rice accessions.In summary,our work develops a novel approach for studying human civilization and migration patterns and provides valuable genomic datasets and resources for future breeding of high-yield and climate-resilient rice varieties. | Chunhui Liu Tianyi Wang Huicha Chen Xiaoding Ma Chengzhi Jiao Di Cui Bing Han Xiaobing Li Aixia Jiao Renchao Ruan Dayuan Xue Yanjie Wang Longzhi Han | 2023 | Molecular Plant2023，16，2： | 3 |
| 9 | Lacunar infarction with leukoaraiosis may aggravate cognitive dysfunction显示文摘This study semi-quantitatively analyzed the effects of leukoaraiosis.Patients with moderate or severe lacunar infarction were found to exhibit low scores on the Montreal Cognitive Assessment Scale (F=12.02,P=0.000),and prolonged P300 Cz2.0 latency (F=16.04,P=0.000).Correlation analysis revealed that the occurrence of leukoaraiosis was negatively correlated with Montreal Cognitive Assessment scores (r=-0.416,P=0.000),and positively correlated with P300 Cz2.0 latency (r=0.538,P=0.000).These findings indicate that leukoaraiosis aggravates cognitive impairment in patients with lacunar infarction,such that more severe leukoaraiosis is associated with more severe cognitive decline. | Dejin Sun Xueqin Zhang Penju Liu Jiechun Chen Jinxia Cao Aixia Zhuang Qinghong Zeng Shouqin Feng Yi Zhang Jiandong Jiang | 2011 | Neural Regeneration Research2011，6，31： | 3 |
| 10 | Comparative transcriptome analysis reveals defense responses against soft rot in Chinese cabbage显示文摘Pectobacterium carotovorum ssp.carotovorum(Pcc)is a necrotrophic bacterial species that causes soft rot disease in Chinese cabbage.In this study,plants harboring the resistant mutant sr gene,which confers resistance against Pcc,were screened from an 800 M2 population mutated by ethyl methane sulfonate(EMS)and scored in vitro and in vivo for lesion size.The transcript profiles showed~512 differentially expressed genes(DEGs)between sr and WT plants occurring between 6 and 12 h postinoculation(hpi),which corresponded to the important defense regulation period(resistance)to Pcc in Chinese cabbage.The downstream defense genes(CPK,CML,RBOH MPK3,and MPK4)of pathogen pattern-triggered immunity(PTI)were strongly activated during infection at 12 hpi in resistant mutant sr;PTI appears to be central to plant defense against Pcc via recognition by three putative pattern recognition receptors(PRRs;BrLYM1-BrCERK1,BrBKK1/SERK4-PEPR1,BrWAKs).Pcc triggered the upregulation of the jasmonic acid(JA)and ethylene(ET)biosynthesis genes in mutant sr,but auxins and other hormones may have affected some negative signals.Endogenous hormones(auxins,JAs,and SA),as well as exogenous auxins(MEJA and BTH),were also verified as functioning in the immune system.Concurrently,the expression of glucosinolate and lignin biosynthesis genes was increased at 12 hpi in resistant mutant sr,and the accumulation of glucosinolate and lignin also indicated that these genes have a functional defensive role against Pcc.Our study provides valuable information and elucidates the resistance mechanism of Chinese cabbage against Pcc infection. | Mengyang Liu Fang Wu Shan Wang Yin Lu Xueping Chen Yanhua Wang Aixia Gu Jianjun Zhao Shuxing Shen | 2019 | Horticulture Research2019，6，1： | 2 |
| 11 | Transcriptomic Analysis of Differentially Expressed Genes and Alternative Splicing Events Associated with Crassulacean Acid Metabolism in Orchids显示文摘Phalaenopsis equestris is an obligate crassulacean acid metabolism(CAM) plant with high ornamental and economic value. CAM photosynthesis is associated with drought tolerance and efficient water utilization, which enhances the survival rate of CAM plants in arid environments.The identification and analysis of CAM-related genes will be helpful to improve our understanding of the regulatory mechanisms of CAM metabolism. In this study, we analyzed RNA-Seq data to identify differentially expressed genes(DEGs) between circadian day and night in P.equestris leaves then performed GO and KEGG functional enrichment analysis. The pathways that were significantly enriched among these DEGs included carbon fixation, circadian clock regulation, glucose metabolism, photosynthesis, and plant hormone signaling. We also used Pac Bio long-read Iso-Seq technology, which identified many alternative splicing events for key genes in CAM-related pathways, including carbon fixation, circadian clock regulation, and stomatal movement. These findings suggested that alternative splicing events might be involved in CAM metabolism. Many unknown or uncharacterized genes were also found to be potentially involved in CAM metabolism. For example, the Peq000162 gene encodes a protein belonging to the Ldp A(light-dependent period) iron-sulfur protein family, and it was found to generate many alternatively spliced products. These findings shed light on CAM metabolic mechanisms in P. equestris along with the molecular functions of key CAM genes. Ultimately, the information may help enhance crop yield and drought tolerance through the introduction of CAM features into C3 crops. | Ying Zhang Wei Dong Xinghua Zhao Aixia Song Kangwei Guo Zhongjian Liu Liangsheng Zhang | 2019 | Horticultural Plant Journal2019，5，6： | 2 |
| 12 | Association of systemic inflammation with marked changes in particulate air pollution in Beijing in 2008显示文摘 | Xiaohua Xu Furong Deng Xinbiao Guo Peng Lv Mianhua Zhong Cuiqing Liu Aixia Wang Kevin Tzan Silis Y. Jiang Morton Lippmann Sanjay Rajagopalan Qingshan Qu Lung-Chi Chen Qinghua Sun | 2012 | Toxicology Letters2012，，2： | 1 |
| 13 | Sucient conditions for bipartite graphs to be super-k-restricted edge connected显示文摘 | Yuan Jun Liu Aixia Wang Shiying | 2009 | Dis- crete Mathematics2009，309，9： | 1 |
| 14 | Evol- ving neural network using real coded genetic algorithm for multispectral image classification显示文摘 | Liu Zhengjun Liu Aixia Wang Changyao | 2004 | Future Gener- ation Computer Systems2004，20，7： | 1 |
| 15 | Association of systemic inflammation with marked changes in particulate air pollution in Beijing in 2008显示文摘 | Xiaohua Xu Furong Deng Xinbiao Guo Peng Lv Mianhua Zhong Cuiqing Liu Aixia Wang Kevin Tzan Silis Y. Jiang Morton Lippmann Sanjay Rajagopalan Qingshan Qu Lung-Chi Chen Qinghua Sun | 2012 | Toxicology Letters2012，，2： | 1 |
| 16 | Identification of potential immune-related prognostic biomarkers of lung cancer using gene co-expression network analysis显示文摘Objective The objective of this study was to identify new carcinogenetic hub genes and develop the integration of differentially expressed genes to predict the prognosis of lung cancer.Methods GSE139032 microarray data packages were downloaded from the Gene Expression Omnibus for planning,testing,and review of data.We identified KRT6C,LAMC2,LAMB3,KRT6A,and MYEOV from a key module for validation.Results We found that the five genes were related to a poor prognosis,and the expression levels of these genes were associated with tumor stage.Furthermore,Kaplan-Meier plotter showed that the five hub genes had better prognostic values.The mean levels of methylation in lung adenocarcinoma(LUAD)were significantly lower than those in healthy lung tissues for the hub genes.However,gene set enrichment analysis(GSEA)for single hub genes showed that all of them were immune-related.Conclusion Our findings demonstrated that KRT6C,LAMC2,LAMB3,KRT6A,and MYEOV are all candidate diagnostic and prognostic biomarkers for LUAD.They may have clinical implications in LUAD patients not only for the improvement of risk stratification but also for therapeutic decisions and prognosis prediction. | Aixia Chen Shengnan Zhao Fei Zhou Hongying Lv Donghai Liang Tao Jiang Rui Liu Lijin Zhu Jingyu Cao Shihai Liu Hongsheng Yu | 2020 | Oncology and Translational Medicine2020，6，6： | 1 |
| 17 | Probabilistic ecological risk assessment and source apportionment of polyeyclie aromatic hydrocarbons in surface sediments from Yellow Sea 显示文摘 | Liu Aixia Lang Yinhai Xue Lidong | 2009 | Bull Environ Contain Tnxicol2009，83，5： | 1 |
| 18 | Evaluation Method of Reliability in the Road Operation Status and Prospects 显示文摘 | Chen Yanyan Gao Aixia Liu Xiaoming Rong Jian | 2003 | Journal of Highway2003，，10： | 1 |
| 19 | Novel Natural Allelic Variations at the Rht-1 Loci in Wheat显示文摘Plant height is an important agronomic trait.Dramatic increase in wheat yield during the'green revolution'is mainly due to the widespread utilization of the Reduced height(Rht)-1 gene.We analyzed the natural allelic variations of three homoeologous loci Rht-A1,Rht-B1,and Rht-D1 in Chinese wheat(Triticum aestivum L.)micro-core collections and the Rht-B1/D1 genotypes in over 1,500 bred cultivars and germplasms using a modifed EcoTILLING.We identifed six new Rht-A1 allelic variations(Rht-A1b–g),eight new Rht-B1 allelic variations(Rht-B1h–o),and six new Rht-D1 allelic variations(Rht-D1e–j).These allelic variations contain single nucleotide polymorphisms(SNPs)or small insertions and deletions in the coding or uncoding regions,involving two frame-shift mutations and 15 missenses.Of which,Rht-D1e and Rht-D1h resulted in the loss of interactions of GID1-DELLA-GID2,Rht-B1i could increase plant height.We found that the Rht-B1h contains the same SNPs and 197 bp fragment insertion as reported in Rht-B1c.Further detection of Rht-B1h in Tibet wheat germplasms and wheat relatives indicated that Rht-B1c may originate from Rht-B1h.These results suggest rich genetic diversity at the Rht-1 loci and provide new resources for wheat breeding. | Aixia Li Wenlong Yang Xueyuan Lou Dongcheng Liu Jiazhu Sun Xiaoli Guo Jing Wang Yiwen Li Kehui Zhan Hong-Qing Ling Aimin Zhang | 2013 | Journal of Integrative Plant Biology2013，55，11： | 1 |
| 20 | Evolving neural network using real coded genetic algorithm(GA)for multispectral image classification显示文摘 | Liu Zhengjun Liu Aixia Wang Changyao | 2004 | Future Generation Computer Systems2004，20，17： | 1 |
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