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| 1 | Heavy metal pollution of soils and vegetables in the midstream and downstream of the Xiangjiang River, Hunan Province显示文摘219 农业土壤和 48 件蔬菜样品的一个总数在湖南省 Xiangjiang 河(Hengyang 长沙节) 从中流并且下游地被收集。累积特征。 | WANG Lixia GUO Zhaohui XIAO Xiyuan CHEN Tongbin LIAO Xiaoyong SONG Jie WU Bin | 2008 | Journal of Geographical Sciences2008，18，3： | 56 |
| 2 | Recent progress of integrated circuits and optoelectronic chips显示文摘Integrated circuits(ICs)and optoelectronic chips are the foundation stones of the modern information society.The IC industry has been driven by the so-called'Moore's law'in the past 60 years,and now has entered the post Moore's law era.In this paper,we review the recent progress of ICs and optoelectronic chips.The research status,technical challenges and development trend of devices,chips and integrated technologies of typical IC and optoelectronic chips are focused on.The main contents include the development law of IC and optoelectronic chip technology,the IC design and processing technology,emerging memory and chip architecture,brain-like chip structure and its mechanism,heterogeneous integration,quantum chip technology,silicon photonics chip technology,integrated microwave photonic chip,and optoelectronic hybrid integrated chip. | Yue HAO Shuiying XIANG Genquan HAN Jincheng ZHANG Xiaohua MA Zhangming ZHU Xingxing GUO Yahui ZHANG Yanan HAN Ziwei SONG Yan LIU Ling YANG Hong ZHOU Jiangyi SHI Wei ZHANG Min XU Weisheng ZHAO Biao PAN Yangqi HUANG Qi LIU Yimao CAI Jian ZHU Xin OU Tiangui YOU Huaqiang WU Bin GAO Zhiyong ZHANG Guoping GUO Yonghua CHEN Yong LIU Xiangfei CHEN Chunlai XUE Xingjun WANG Lixia ZHAO Xihua ZOU Lianshan YAN Ming LI | 2021 | Science China(Information Sciences)2021，64，10： | 7 |
| 3 | Electroacupuncture relieves irritable bowel syndrome by increasing expression of nucleotide-binding oligomerization domain protein-like receptor family pyrin domain containing 6 in water-avoidance stress mice显示文摘OBJECTIVE: To investigate the effect of electroacupuncture(EA) on irritable bowel syndrome(IBS) in mice through regulating nucleotide-binding oligomerization domain protein-like receptor family pyrin domain containing 6(NLRP6).METHODS: Water-avoidance stress(WAS) mice model was used to investigate the effects and the mechanism of EA. Abdominal withdrawal reflex test, open field test, and intestinal motility test were used to evaluate visceral sensitivity, anxiety,and intestinal motility in mice. The expressions of NLRP6, Mucin-2(MUC2) and E-cadherin were determined using immunofluorescence and Western blotting assays.RESULTS: EA significantly upregulated the expression of NLRP6 in the intestine of mice. Moreover, EA increased the expressions of MUC2 and E-cadherin in WAS mice.CONCLUSION: Our study found that the relief of IBS symptoms by EA may involve the increase in the expression of NLRP6 in WAS mice. | Song Yafang Geng Hao Chen Lu Wu Xiaoliang Yuan Mengqian Xu Wanli Guo Jing Sun Jianhua Pei Lixia | 2020 | Journal of Traditional Chinese Medicine2020，40，3： | 3 |
| 4 | Polyphenolic antioxidant profiles of yellow camellia显示文摘 | LIXIA SONG XIANGSHE WANG XUEQIN ZHENG | 2011 | Food Chemistry2011，，129： | 1 |
| 5 | Food grade fungal stress on germinating peanut seedsindueed phytoalexins and enhanced polyphenolic antioxidants 显示文摘 | Wu Ziyun Song Lixia Huang Dejian | 2011 | Journal of Agricul- tural and Food Chemistry2011，59，11： | 1 |
| 6 | The mechanism of a new type of modified clay controlling Phaeocystis globosa growth显示文摘Phaeocystis globosa is a harmful algal bloom(HAB)species worldwide.Using modified clay(MC)to control HABs and to mitigate their adverse effects is currently a commonly used method in China.In this paper,the effects of oxidized composite modified clay(OXI-MC)on P.globosa were studied from different perspectives.The results show that the OXI-MC could effectively remove P.globosa and inhibit both the growth of residual algal cells and the formation of new colonies.The P.globosa algal biomass removal efficiencies after 3 h reached 90%at a dose of 0.1 g/L,and the number of colonies with different particle sizes was greatly reduced.Compared with those of the control,the superoxide dismutase(SOD)activity,catalase(CAT)activity,and malondialdehyde(MDA)content of the residual algae significantly increased,indicating that OXI-MC caused oxidative stress in the algal cells.In addition,we evaluated the effects of OXI-MC on the photosynthesis of residual microalgae and found that the maximal photochemical efficiency of photosystem II(PSII)under dark adaptation(F v/F m)and actual photochemical efficiency of PSII(ФPSII)decreased,severely damaging the photosynthesis efficiency,implying that OXI-MC effected the photosynthesis system of P.globosa.The results of this study clarify that OXI-MC could remove the most of algal cells and break up the colonies of P.globosa by collision,flocculation,and releasing active substances,as well as inhibit effectively the growth and colony formation of residual P.globosa by causing oxidative stress,reducing photosynthesis activity,accelerating the degradation of polysaccharides,and inhibiting the formation of colonies. | QIU Lixia YU Zhiming CAO Xihua JI Hena SONG Xiuxian | 2020 | Journal of Oceanology and Limnology2020，38，4： | 1 |
| 7 | The involvement of ERK/CREB/Bcl-2 in depression-like behavior in prenatally stressed offspring rats显示文摘 | Lixia Guan Ning Jia Xiaoyan Zhao Xiaohua Zhang Guokui Tang Li Yang Hongli Sun Dan Wang Qian Su Qian Song Dongge Cai Qing Cai Hui Li Zhongliang Zhu | 2013 | Brain Research Bulletin2013，，： | 1 |
| 8 | Pore characteristics and electrochemical performance of ordered mesoporous carbons for electric double-layer capacitors显示文摘 | Li Lixia Song Huaihe Chen Xiaohong | 2006 | Electrochimica Acta2006，51，26： | 1 |
| 9 | Using mesoporous carbon electrodes for brackishwater desalination 显示文摘 | Zou Linda Li Lixia Song Huaihe | 2008 | Water Research2008，42，89： | 1 |
| 10 | Ordered mesoporous carbons from the carbonization of sulfuric-treated silica/ triblock copolymer/sucrose composites显示文摘 | Lixia Li Huaihe Song Xiaohong Chen | 2006 | Microporous and mesoporous materials2006，94，： | 1 |
| 11 | Electroacupuncture at Tianshu(ST25) and Zusanli(ST36) alleviates stress-induced irritable bowel syndrome in mice by modulating gut microbiota and corticotropin-releasing factor显示文摘OBJECTIVE: To investigate whether electroacupuncture(EA) at bilateral Tianshu(ST25) and Zusanli(ST36) acupoints could alleviate stress-induced irritable bowel syndrome(IBS) and evaluate its effect on gut microbiota and corticotropin-releasing factor(CRF). METHODS: Thirty C57BL/6 mice were randomly divided into the normal, water avoidance stress(WAS), and WAS+EA groups(10 mice per group). An experimental model of IBS was established by exposing the animals to WAS. The mice were treated with EA at the bilateral Tianshu(ST25) and Zusanli(ST36) acupoints. The abdominal withdrawal reflex test was conducted to evaluate visceral sensitivity in IBS. Gut microbiota was analyzed using 16S r RNA sequencing and analysis. The expression of CRF was determined using immuneofluorescence and quantitative real-time polymerase chain reaction. RESULTS: EA alleviated visceral hypersensitivity in a mouse model of WAS-induced IBS. It modulated the dysbiosis of gut microbiota induced by WAS. Moreover, it suppressed the WAS-induced overexpression of CRF in colon tissues. CONCLUSION: The findings of this study suggest that EA alleviated WAS-induced IBS via mechanisms possibly involving the modulation of the dysbiosis of gut microbiota and suppression of CRF expression. | SUN Mengzhu ZHANG Yujie SONG Yafang GUO Jing ZHAO Tingting WANG Yuhang PEI Lixia SUN Jianhua | 2022 | Journal of Traditional Chinese Medicine2022，42，5： | 1 |
| 12 | Highly efficient multiplex base editing:One-shot deactivation of eight genes in Shewanella oneidensis MR-1显示文摘Obtaining electroactive microbes capable of efficient extracellular electron transfer is a large undertaking for the scalability of bio-electrochemical systems.Inevitably,researchers need to pursue the co-modification of multiple genes rather than expecting that modification of a single gene would make a significant contribution to improving extracellular electron transfer rates.Base editing has enabled highly-efficient gene deactivation in model electroactive microbe Shewanella oneidensis MR-1.Since multiplexed application of base editing is still limited by its low throughput procedure,we thus here develop a rapid and efficient multiplex base editing system in S.oneidensis.Four approaches to express multiple gRNAs were assessed firstly,and transcription of each gRNA cassette into a monocistronic unit was validated as a more favorable option than transcription of multiple gRNAs into a polycistronic cluster.Then,a smart scheme was designed to deliver one-pot assembly of multiple gRNAs.3,5,and 8 genes were deactivated using this system with editing efficiency of 83.3%,100%and 12.5%,respectively.To offer some nonrepetitive components as alternatives genetic parts of sgRNA cassette,different promoters,handles,and terminators were screened.This multiplex base editing tool was finally adopted to simultaneously deactivate eight genes that were identified as significantly downregulated targets in transcriptome analysis of riboflavin-overproducing strain and control strain.The maximum power density of the multiplex engineered strain HRF(8BE)in microbial fuel cells was 1108.1 mW/m2,which was 21.67 times higher than that of the wild-type strain.This highly efficient multiplexed base editing tool elevates our ability of genome manipulation and combinatorial engineering in Shewanella,and may provide valuable insights in fundamental and applied research of extracellular electron transfer. | Yaru Chen Meijie Cheng Yan Li Lin Wang Lixia Fang Yingxiu Cao Hao Song | 2023 | Synthetic and Systems Biotechnology2023，8，1： | 1 |
| 13 | Salvianolic acid B inhibits Aβ fibril formation and disaggregates preformed fibrils and protects against Aβ-induced cytotoxicty显示文摘 | Siva Sundara Kumar Durairajan Qiuju Yuan Lixia Xie Wing-Sai Chan Wan-Fung Kum Irene Koo Chenli Liu Youqiang Song Jian-Dong Huang William L. Klein Min Li | 2007 | Neurochemistry International2007，，4： | 1 |
| 14 | Ordered mesoporous carbons synthesized by a modified sol–gel process for electrosorptive removal of sodium chloride显示文摘 | Lixia Li Linda Zou Huaihe Song Gayle Morris | 2008 | Carbon2008，，3： | 1 |
| 15 | Polyphenolic antioxi- dant profiles of yellow camellia 显示文摘 | Lixia Song Xiangshe Wang Xueqin Zheng | 2011 | Food Chemistry2011，，129： | 1 |
| 16 | Pore characteristic and electrochemical performance of ordered mesoporous carbons for electric double-layer capacitors显示文摘 | LI Lixia SONG Huaihe CHEN Xiaohong | 2006 | Electrochemica Acta2006，51，26： | 1 |
| 17 | Changes in the volatile compounds and chemical and physical properties of Yali pear ( Pyrus bertschneideri Reld) during storage显示文摘 | Ji Luan Chen Shijie Yan Zuoshan Feng Lixia Xiao Xiao Song Hu | 2005 | Food Chemistry2005，，2： | 1 |
| 18 | Using mesoporous carbon electrodes for brackish water desalination显示文摘 | Linda Zou Lixia Li Huaihe Song Gayle Morris | 2008 | Water Research2008，，8： | 1 |
| 19 | Effect of compounding process on the structure and electrochemical properties of ordered mesoporous carbon/polyaniline composites as electrodes for supercapacitors显示文摘 | Li Lixia Song Huaihe Zhang Qincang | 2009 | Journal of Power Sources2009，187，： | 1 |
| 20 | Temperature compensation in deformation testing for smart concrete structures 显示文摘 | Song Xianhui Zheng Lixia Li Zhuoqiu | 2006 | Key Engineering Material2006，3，： | 1 |
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