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122篇 您的检索式:作者名="Lander N"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2Reactive oxygen species have a causal role in multiple forms of insulin resistance显示文摘Houstis N Rosen ED Lander ES 2006Nature2006,440,7086:1
3Reactive oxygen species have a causal role in multiple forms of insulin resistance 显示文摘Houstis N Rosen ED Lander ES 2006Nature2006,440,7086:1
4Retesting after initial failure, coaching rumors, and warnings against faking in online personality measures for selection显示文摘Landers R N Sackett P R Tuzinski K A 2011Journal of Applied Psychology2011,96,1:1
5A Study of the Hydrogen Distribution in Coal-like Materials by High-resolution Nuclear Magnetic Resonance Spec- tropcopy I The Measurement and Interpretation of the Spectra显示文摘Brown J K Lander W R Sheppard N 1960Fuel1960,39,1:1
6Reactive oxygen species have a causal role in multiple forms of insulin resistance显示文摘Houstis N Rosen ED Lander ES 2006Nature2006,440,:1
7A real options approach to valuing strategic flexibility in uncertain construction projects 显示文摘Ford D N Lander D M Voyer J J 2002Construction Management and Economics2002,,20:1
8Reactive oxygen species have a causal role in muhiple forms of insulin resistance 显示文摘Houstis N Rosen E D Lander E S 2006Nature2006,440,7086:1
9A comparison of modeling and imaginary in the acqui- sition and retention of motor skills 显示文摘Ram N Riggs S M Landers D M McCullagh P 2007Journal of Sports Sciences2007,25,5:1
10The genetic dissection of complex traits 显示文摘Lander E S Schork N J 1994Science1994,265,:1
11Reactive oxygen species have a causal role in multiple forms of insulin resistance 显示文摘N Houstis E D Rosen E S Lander 2006Nature2006,440,7086:1
12Reactive oxygen species have a causal role in multiple forms of insulin resistance显示文摘Houstis N Rosen ED Lander ES 2006Nature2006,440,:1
13Therapeutic EphA2Gene targeting in vivo using neutual liposomal small intering RNA delivery 显示文摘CHARLES N LANDER Jr CHAVEZ-REYES A 2005Cancer Res2005,65,:1
14Reactive oxygen species have a causal role in multiple forms of insulin resistance显示文摘Houstis N Rosen ED Lander ES 2006Nature2006,440,:1
15Reactive oxygen species have a causal role in multiple forms of insulin resistance显示文摘Houstis N Rosen ED Lander ES 2006Nature2006,440,7086:1
16Reactive oxygen species have a causal role in multiple forms of insulin resistance显示文摘Houstis N Rosen ED Lander ES 2006Nature2006,440,7086:1
17Reactive oxygen species have a causal role in multiple forms of insulin resistance显示文摘Houstis N Rosen ED Lander ES 2006Nature2006,440,7086:1
18Reactive oxygen species have a causal role inmultiple forms of insulin resistance显示文摘Houstis N Rosen ED Lander ES 2006Nature2006,440,:1
19Reactive oxygen species have a causal role in multiple forms of insulin resistance显示文摘Houstis N ED Rosen ES Lander 2006Nature2006,440,7086:1
20A molecular signature of metastasis in primary solid tumors显示文摘Ramaswamy S Ross K N Lander E S 2003Nat Genet2003,33,1:1
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