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| 1 | 减少急性冠状动脉综合征和卒中患者求医的延误——美国心脏协会心血管护理委员会和卒中委员会的科学声明显示文摘在寻求急性冠状动脉综合征和卒中症状的治疗方面,患者延误是限制提供这些疾病的确定性治疗的主要因素。尽管数十年来的研究和公众教育活动一直旨在缩短患者延误时间,但大多数患者仍然不能及时求医。在本科学声明中,我们总结了以下证据:(1)证明早期治疗的益处;(2)描述患者延误问题的程度;(3)确定与患者延误及时求医有关的因素;(4)揭示当前减少患者延误措施的不足。最后,提出临床实践和今后研究的建议。 | Debra K. Moser Laura P. Kimble Mark J. Alberts Angelo Alonzo Janet B. Croft Kathleen Dracup Kelly R. Evenson Alan S. Go Mary M. Hand Rashmi U. Kothari George A. Mensah Dexter L. Morris Arthur M. Pancioli Barbara Riegel Julie Johnson Zerwic 李宏建 曲东锋 | 2006 | 国际脑血管病杂志2006，14，10： | 39 |
| 2 | Phased,chromosome-scale genome assemblies of tetraploid potato reveal a complex genome,transcriptome,and predicted proteome landscape underpinning genetic diversity显示文摘Cultivated potato is a clonally propagated autotetraploid species with a highly heterogeneous genome.Phased assemblies of six cultivars including two chromosome-scale phased genome assemblies revealed extensive allelic diversity,including altered coding and transcript sequences,preferential allele expression,and structural variation that collectively result in a highly complex transcriptome and predicted proteome,which are distributed across the homologous chromosomes.Wild species contribute to the extensive allelic diversity in tetraploid cultivars,demonstrating ancestral introgressions predating modern breeding efforts.As a clonally propagated autotetraploid that undergoes limited meiosis,dysfunctional and deleterious alleles are not purged in tetraploid potato.Nearly a quarter of the loci bore mutations are predicted to have a high negative impact on protein function,complicating breeder’s efforts to reduce genetic load.The StCDF1 locus controls maturity,and analysis of six tetraploid genomes revealed that 12 allelic variants of StCDF1 are correlated with maturity in a dosage-dependent manner.Knowledge of the complexity of the tetraploid potato genome with its rampant structural variation and embedded deleterious and dysfunctional alleles will be key not only to implementing precision breeding of tetraploid cultivars but also to the construction of homozygous,diploid potato germplasm containing favorable alleles to capitalize on heterosis in F1 hybrids. | Genevieve Hoopes Xiaoxi Meng John P.Hamilton Sai Reddy Achakkagari Fernanda de Alves Freitas Guesdes Marie E.Bolger Joseph J.Coombs Danny Esselink Natalie R.Kaiser Linda Kodde Maria Kyriakidou Brian Lavrijssen Natascha van Lieshout Rachel Shereda Heather K.Tuttle Brieanne Vaillancourt Joshua C.Wood Jan Mde Boer Nolan Bornowski Peter Bourke David Douches Herman Jvan Eck Dave Ellis Max J.Feldman Kyle M.Gardner Johannes C.P.Hopman Jiming Jiang Walter S.De Jong Joseph C.Kuhl Richard G.Novy Stan Oome Vidyasagar Sathuvalli Ek Han Tan Remco A.Ursum M.Isabel Vales Kelly Vining Richard G.F.Visser Jack Vossen G.Craig Yencho Noelle L.Anglin Christian W.B.Bachem Jeffrey B.Endelman Laura M.Shannon Martina V.Stromvik Helen H.Tai Bjorn Usadel C.Robin Buell Richard Finkers | 2022 | Molecular Plant2022，15，3： | 4 |
| 3 | Umbilical Herniorrhapy in Cirrhosis: Improved Outcomes with Elective Repair显示文摘 | Stephen H. Gray Catherine C. Vick Laura A. Graham Kelly R. Finan Leigh A. Neumayer Mary T. Hawn | 2008 | Journal of Gastrointestinal Surgery2008，，4： | 2 |
| 4 | Micromechanical adhesion force measurements between tetrahydrofuran hydrate particles显示文摘 | Taylor Craig J Dieker Laura E Miller Kelly T | 2007 | Journal of Colloid and Interface Science2007，306，： | 1 |
| 5 | Teaching and physics education research: bridging the gap显示文摘 | James M Fraser Anneke L Timan Kelly Miller Jason E Dowd Laura Tucker Eric Mazur | 2014 | Reports on Progress in Physics2014，，3： | 1 |
| 6 | Micromechanical adhesion force measurements between tetrahydrofuran hydrate particles显示文摘 | Craig J T Laura E D Kelly T M | 2007 | Journal of Colloid and Interface Science2007，306，： | 1 |
| 7 | Micromechanical adhesion force measurements between tetrahydrofuran hydrate particles显示文摘 | Taylor Craig J Dieker Laura E Miller Kelly T Koh C A Sloan E D | | 0，，： | 1 |
| 8 | Reducing Delay in Seeking Treatment by Patients With Acute Coronary Syndrome and Stroke: A Scientific Statement From the American Heart Association Council on Cardiovascular Nursing and Stroke Council*显示文摘 | Debra K. Moser Laura P. Kimble Mark J. Alberts Angelo Alonzo Janet B. Croft Kathleen Dracup Kelly R. Evenson Alan S. Go Mary M. Hand Rashmi U. Kothari George A. Mensah Dexter L. Morris Arthur M. Pancioli Barbara Riegel Julie Johnson Zerwic | 2007 | The Journal of Cardiovascular Nursing2007，，4： | 1 |
| 9 | Central Corneal Thickness: Congenital Cataracts and Aphakia显示文摘 | Kelly W. Muir Lois Duncan Laura B. Enyedi David K. Wallace Sharon F. Freedman | 2007 | American Journal of Ophthalmology2007，，4： | 1 |
| 10 | Development, optimization, and characterization of electrospun poly(lactic acid) nanofibers containing multi‐walled carbon nanotubes显示文摘 | Seth D.McCullen Kelly L.Stano Derrick R.Stevens Wesley A.Roberts Nancy A.Monteiro‐Riviere Laura I.Clarke Russell E.Gorga | 2007 | J Appl Polym Sci2007，，3： | 1 |
| 11 | Design, synthesis and biological evaluation of α-substituted isonipecotic acid benzothiazole analogues as potent bacterial type II topoisomerase inhibitors显示文摘 | Lorraine C. Axford Piyush K. Agarwal Kelly H. Anderson Laura N. Andrau John Atherall Stephanie Barker James M. Bennett Michael Blair Ian Collins Lloyd G. Czaplewski David T. Davies Carlie T. Gannon Dushyant Kumar Paul Lancett Alastair Logan Christopher J. | 2013 | Bioorganic & Medicinal Chemistry Letters2013，，24： | 1 |
| 12 | Receiver-operatingcharacteristic analysis for evaluating diagnostic tests andpredictive models显示文摘 | Kelly H Z A James O'Malley Laura M | 2007 | Circulation2007，115，： | 1 |
| 13 | Information-motivation-behavioral skills (IMB) model: Testing direct and mediated treatment effects on condom use among women in low-income housing显示文摘 | Eileen S. Anderson David A. Wagstaff Timothy G. Heckman Richard A. Winett Roger A. Roffman Laura J. Solomon Victoria Cargill Jeffrey A. Kelly Kathleen J. Sikkema | 2006 | Annals of Behavioral Medicine2006，，1： | 1 |
| 14 | Evaluation of a real-time polymerase chain reaction assay for Pseudorabies virus surveillance purposes显示文摘 | Eraldo L. Zanella Laura C. Miller Kelly M. Lager Troy T. Bigelow | 2012 | Journal of Veterinary Diagnostic Investigation2012，，4： | 1 |
| 15 | Measuring the Effects of Online Health Information for Patients: Item Generation for an E-health Impact Questionnaire显示文摘 | Laura Kelly Crispin Jenkinson Sue Ziebland | 2013 | Patient Education and Counseling2013，，93： | 1 |
| 16 | The role of parent health literacy among urban children with persistent asthma 显示文摘 | LAURA P S KELLY M C LEE S | 2009 | Patient Education and Counseling2009，，75： | 1 |
| 17 | A Clinical Algorithm for Fine-Needle Aspiration Molecular Testing Effectively Guides the Appropriate Extent of Initial Thyroidectomy显示文摘 | Linwah Yip Laura I. Wharry Michaele J. Armstrong Ari Silbermann Kelly L. McCoy Michael T. Stang Nobuyuki P. Ohori Shane O. LeBeau Christopher Coyne Marina N. Nikiforova Julie E. Bauman Jonas T. Johnson Mitch E. Tublin Steven P. Hodak Yuri E. Nikiforov Sal | 2014 | Annals of Surgery2014，，1： | 1 |
| 18 | Hypertrophic Cardiomyopathy With Cardiac Rupture and Tamponade Caused by Congenital Disorder of Glycosylation Type Ia显示文摘 | Laura Rudaks Chad Andersen T. Khong Andrew Kelly Michael Fietz Christopher Barnett | 2012 | Pediatric Cardiology2012，，5： | 1 |
| 19 | The role of parent health literacy among urban children with persistent asthma显示文摘 | Laura P. Shone Kelly M. Conn Lee Sanders Jill S. Halterman | 2009 | Patient Education and Counseling2009，，3： | 1 |
| 20 | Recent Developments in Public Health Nursing in the Americas显示文摘 | Nigenda Gustavo Maga?a-Valladares Laura Cooper Kelly Ruiz-Larios Jose Arturo | 2010 | International Journal of Environmental Research and Public Health2010，，3： | 1 |
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