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| 1 | Assessment of the anterior spinal artery and the artery of Adamkiewicz using multi-detector CT angiography显示文摘在下降的治疗以后的针的绳索的背景损坏胸并且 thoracoabdominal 大动脉的动脉瘤是不平常却破坏的复杂并发症。Adamkiewicz 的动脉(也称为) 在更低的胸、腰部的水平是前面的针的动脉(ASA ) 的主要动脉的供应。这研究的目的是评估前面的针的动脉和 Adamkiewicz 的动脉的可视化,为用多察觉者的察觉率的影响因素划 CT (MDCT ) 。方法 99 个连续病人(31 个女人和 68 个男人;年龄范围, 25-90 年;平均年龄 61.3 年) 为要求外科的干预(31 大动脉的动脉瘤, 45 解剖, 5 内部 hematoma,和 18 正常) 的胸的大动脉的损害的怀疑地,从大动脉的拱门经历了 CT angiography 到大动脉的分叉。横向的节, multiplanar 改革和薄最大的紧张设计被用来估计 ASA 并且也称为。ASA 并且也称为起源和 CT 获得参数的水平被记录。图象, T11 身体(脊椎的集体索引) 的团的一个索引,下的胖厚度,和在大动脉的拱门以内并且在 T11 水平的 CT 值的 contrast-to-noise 比率被测量。ASA 并且也称为的察觉相对获得参数,扫描特征,和大动脉的损害类型被评估。差别与 Wilcoxon 等级和和 t 测试被估计。结果 ASA 在 18 个病人(18%) 在 51 个病人(52%) 和 AKA 被设想。ASA 与 2.5-3.0 公里厚度与 1.25 公里厚度并且在 15/32 病人(47%) 在 36/67 病人(54%) 被识别。这差别没完成意义(P=0.13 ) 。ASA 和 AKA 的察觉率被脊椎的集体索引和 contrast-to-noise 比率影响(P < 0.05 ) 。下的脂肪的数量影响了 ASA 的察觉率(P < 0.05 ) 然而并非 AKA。在 ASA 察觉的 CT 扫描,分别地,而,在在拱门并且在 T11 的主动脉的吝啬的 CT 价值是 360 和 358 胡在没有 ASA 察觉的 CT 扫描,在在拱门并且在 T11 的主动脉的 CT 价值更低( P < 0.05 ), 297 和 317 胡, respectively.Conclusions ASA 并且也称为不太经常比以前的报告在我们的队被检测。ASA 并且也称为的可视化被大动脉的改进显著地影响, =vertebral 团索引“,并且 contrast-to-noise 比率。 | ZHAO Shao-hong, Laura Logan Pamela Schraedley Geoffrey D. Rubin | 2009 | Chinese Medical Journal2009，，2： | 5 |
| 2 | Design, synthesis and biological evaluation of α-substituted isonipecotic acid benzothiazole analogues as potent bacterial type II topoisomerase inhibitors显示文摘 | Lorraine C. Axford Piyush K. Agarwal Kelly H. Anderson Laura N. Andrau John Atherall Stephanie Barker James M. Bennett Michael Blair Ian Collins Lloyd G. Czaplewski David T. Davies Carlie T. Gannon Dushyant Kumar Paul Lancett Alastair Logan Christopher J. | 2013 | Bioorganic & Medicinal Chemistry Letters2013，，24： | 1 |
| 3 | Esophageal injury by apple cider vinegar tablets and subsequent evaluation of products显示文摘 | LAURA L H LOGAN H W JERALD C F | 2005 | Journal of the American Dietetic Association2005，，1： | 1 |
| 4 | Multi-detector CT angiography for the assessment of anterior spinal artery and artery of Adamkiewicz patency in patients suspected of having thoracic aortic pathology显示文摘Objective To evaluate the visualization of the anterior spinal artery (ASA) and the artery of Adamkiewicz (AKA) as well as the affecting factors for the detection rate using multidetector row CT (MDCT). Methods Ninety-nine consecutive patients (31 women and 68 men; age range, 25-90 years; average age 61.3 years) with suspicion for thoracic aortic lesions necessitating surgical intervention (31 aortic aneurysm, 45 dissection, 5 intramural hematoma, and 18 normal), underwent 16-slice MDCT angiography from the aortic arch to the aortic bifurcation. Transverse sections, multiplanar reformations (MPR) and thin maximum intensity projections (MIP) were used to assess the ASA and AKA. The level of the ASA and AKA origins and CT acquisition parameters were recorded. The contrast-to-noise ratio (CNR) of the image, an index of the mass of the T11 body (vertebral mass index), the subcutaneous fat thickness,and the CT value within the aortic arch and at the T11 level were measured. The detection of the ASA and AKA was evaluated relative to the acquisition parameters, scan characteristics, and aortic lesion type. Differences were assessed with Wilcoxon rank-sum and t tests. Results The ASA was visualized in 51 patients (52%) and the AKA in 18 patients (18 %). The ASA was identified in 36/67 (54%)patients with 1.25 mm thickness and in15/32 (47%) patients with 2.5-3.0 mm thickness. This difference did not achieve significance (P=0.13). The detection rate of the ASA and the AKA was influenced by vertebral mass index and the CNR (P<0.05). The amount of subcutaneous fat affected the detection rate of the ASA (P<0.05) but not the AKA. In CT scans with ASA detection, the mean CT values in the aorta at the arch and at T11 were 360 and 358 HU, respectively; whereas in CT scans without ASA detection, the CT values in the aorta at the arch and at T11 were lower (297 and 317 HU, respectively; both P<0.05). Conclusion The ASA and AKA were less frequently detected in our cohorts than previous reports. The visualization of the ASA and AKA was significantly affected by aortic enhancement, the 'vertebral mass index', and the CNR. | Laura Logan Pamela Schraedley Geoffrey D.Rubin | 2006 | Journal of Geriatric Cardiology2006，3，1： | 1 |
| 5 | 豆帐篷显示文摘罗宾的妹妹生病了,罗宾被爸爸送到了奶奶家。望着爸爸远去的车影,罗宾伤心地哭起来、奶奶极力安慰着罗宾,可不争气的眼泪就是止不住,奶奶带罗宾来到了后花园,那里有一个倒放的冰激凌筒状的篷子,外面覆盖着长满心形叶子的藤蔓,十分漂亮。奶奶称它为“豆帐篷”,在这个神奇的“帐篷”中,罗宾就好像是神气的女王.暂时忘记了悲伤。不过好景不长,第二天,罗宾又因为思念爸爸妈妈伤心落泪、奶奶安慰着她:“伤心虽然没什么不可以,不过开心不是更好吗?”从那之后,罗宾就再没流过泪。 | Leslie Davidson Laura Logan | 2016 | 英语沙龙(原版阅读)2016，，7： | 0 |
| 6 | Prevalence of significant liver disease in human immunodeficiency virus-infected patients exposed to Didanosine: A cross sectional study显示文摘AIM To identify significant liver disease [including nodular regenerative hyperplasia(NRH)] in asymptomatic Didanosine(DDI) exposed human immunodeficiency virus(HIV) positive patients.METHODS Patients without known liver disease and with > 6 mo previous DDI use had liver stiffness assessed by transient elastography(TE). Those with alanine transaminase(ALT) above upper limit normal and/or TE > 7.65 k Pa underwent ultrasound scan(U/S). Patients with:(1) abnormal U/S; or(2) elevated ALT plus TE > 7.65 k Pa;or(3) TE > 9.4 k Pa were offered trans-jugular liver biopsy(TJLB) with hepatic venous pressure gradient(HVPG) assessment.RESULTS Ninety-nine patients were recruited, median age 50 years(range 31-70), 81% male and 70% men who have sex with men. Ninety-five percent with VL < 50 copies on antiretroviral therapy with median CD4 count 639 IU/L. Median DDI exposure was 3.4 years(range 0.5-14.6). Eighty-one had a valid TE readings(interquartile range/score ratio < 0.3): 71(88%) < 7.65 k Pa, 6(7%) 7.65-9.4 k Pa and 4(6%) > 9.4 k Pa. Seventeen(17%) met criteria for TJLB, of whom 12 accepted. All had HVPG < 6 mm Hg. Commonest histological findings were steatosis(n = 6), normal architecture(n = 4) and NRH(n = 2), giving a prevalence of previously undiagnosed NRH of 2%(95%CI: 0.55%, 7.0%).CONCLUSION A screening strategy based on TE, liver enzymes and U/S scan found a low prevalence of previously undiagnosed NRH in DDI exposed, asymptomatic HIV positive patients. Patients were more likely to have steatosis highlighting the increased risk of multifactorial liver disease in this population. | Sarah Logan Alison Rodger Laura Maynard-Smith James O'Beirne Thomas Fernandez Filippo Ferro Colette Smith Sanjay Bhagani | 2016 | World Journal of Hepatology2016，8，36： | 0 |
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