|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification显示文摘MLL-AF4 熔化基因是在在婴儿的高风险的尖锐成淋巴细胞的白血病的一个特点 genomic 错误。尽管 MLL-AF4 在人的开发期间出生前地产生,这很好被建立,它在在 utero 的造血的开发的效果仍然保持未经勘探。我们创造了一个人特定的细胞的系统在 MLL-AF4-expressing 人的胚胎的干细胞(hESCs ) 学习早 hemato-endothelial 开发。介绍的功能的研究,同种细胞的分析和基因表示表明在 hESCs 的 MLL-AF4 的那表情有 phenotypic,功能并且基因表示影响。MLL-AF4 在 hESCs 充当全球 transcriptional 使活跃之物和 homeobox 基因表示的一个积极管理者。机能上地, MLL-AF4 从 hESCs 提高 hemogenic 先锋的说明,但是强烈损害进一步造血的承诺赞成 endothelial 房间命运。MLL-AF4 hESCs transcriptionally 被告知向对 endothelial 成熟敏感的 hemogenic 先锋区分,由联系到 vascular-endothelial 功能和早造血作用的主人基因的显著 upregulation 思考了。而且,我们报导那 MLL-AF4 表情不是足够的转变导出 hESC 的造血的房间。这个工作说明 hESCs 怎么可以提供唯一的卓见进人的开发并且推进我们理解白血病的熔化基因,知道出生前地产生,调整人的胚胎的造血的说明。 | Clara Bueno Rosa Montes Gustavo J Melen Verdnica Ramos-Mejia Pedro J Real Ver6nica Ayllo'n Laura Sanchez Gertmdis Ligero Inmaculada Gutierrez-Aranda Agustin F Femfindez Mario F Fraga Inmaculada Moreno-Gimeno Deborah Btlrks Maria del Carmen Plaza-Calonge Juan C Rodriguez-Manzaneque Pablo Menendez | 2012 | Cell Research2012，22，6： | 2 |
| 2 | Synthesis and biological evaluation of an anticancer vaccine containing the C-glycoside analogue of the Tn epitope 显示文摘 | Francesco P Laura C Maria R | 2001 | Bioconjug Chem2001，12，3： | 1 |
| 3 | Effect of inhibitors released during steam-explosion treatment of poplar wood on subsequent enzymatic hydrolysis and SSF显示文摘 | Maria C Laura C Alberto G | 2004 | Biotechnology Progress2004，20，1： | 1 |
| 4 | Influence of sub-lethal antiox- idant doses, water potential and temperature on growth, sclero- tia, aflatoxins and aflD( = nor-1 ) expression by Aspergillus fla- vus RCP08108显示文摘 | Maria A P Laura C R Miriam E | 2012 | Microbiol Res2012，167，8： | 1 |
| 5 | Added value of Virtual Touch IQ shear wave elastography in the ul- trasound assessment of breast lesions显示文摘 | Victor I Laura Maria C Ariane D | 2014 | Eur J Radi- oi2014，83，5： | 1 |
| 6 | A study of the retrograda- tion process in five argentine rice starches显示文摘 | LAURA B I de MISHIMA B L MARIA C A | 2010 | LWT-Food Science and Technology2010，43，4： | 1 |
| 7 | A small molecule targeting the multifactorial nature of Alzheimer's disease 显示文摘 | Andrea C Maria Laura B Simona C | 2007 | Angew Chemi Int Engl2007，46，20： | 1 |
| 8 | Production of hydrogen by steam reforming of C3 organics over Pd-Cu/γ-Al2O3 catalyst显示文摘 | Carlo R Laura A Maria C | 2006 | International Journal of Hydrogen Energy2006，31，： | 1 |
| 9 | A study of the retrogradation process in five argentine rice starches显示文摘 | LAURA B ITURRIAGA BEATRIZ LOPEZ DE MISHIMA MARIA C ANON | 2009 | LWT - Food Science and Technology2009，43，4： | 1 |
| 10 | Comparison of different detoxification methods for steam-exploded poplar wood as a substrate for the bioproduction of ethanol in SHF and SSF 显示文摘 | Maria C Laura C Alberto G | 2004 | Process Biochem2004，39，： | 1 |
| 11 | Immunosuppression Interleukin-10 Synthesis and Apoptosis are Induced in Rats Inoculated with Cryptococcus Neoformans Glucuronoxylomanna显示文摘 | LAURA S C JOSE L B MARIA P A | 2004 | Immunology2004，113，： | 1 |
| 12 | Determination of 1- and d-camitine in dietary food supplements using capillary electrophoresis-tandem mass spectrometry显示文摘 | Laura S H Maria C P Carmen G R | 2010 | Food Chemistry2010，120，： | 1 |
| 13 | Enhanced therapeutic effect of multiple injections of HSV TK+GCV gene therapy in combination with ionizing radiation in a mouse mammary tumor model 显示文摘 | MARIA T V MADHU C LAURA A | 2002 | Int J Radiat Oncol Biol Phys2002，51，4： | 1 |
| 14 | Mosaicism Solid Gold supports the causality of a noncoding A-to-G transition in the determinism of the callipyge phenotype显示文摘 | Maria S Karin S Laura G C | 2003 | Genetics2003，163，： | 1 |
| 15 | Atrial natriuretic peptide modifies arterial blood pressure through nitric oxide pathway in rats显示文摘 | Maria A C Laura V G B Monica P M | 2000 | Hypertension2000，35，： | 1 |
| 16 | Enhanced therapeutic effect of multiple injections of HSV-TK+GCVgene therapy in combination with ionizing radiation in a mouse mammary tumor model 显示文摘 | Maria TV Madhu C Laura A | 2002 | Int J Radiation Oncology Biol Phys2002，51，4： | 1 |
| 17 | Polycyclic aromatic hydrocar- bons (PAHs) in two Spanish traditional smoked sausage varieties: 'Androlla'and 'Botillo'显示文摘 | JOSE M L LAURA P MARIA C | 2010 | Meat Science2010，86，3： | 1 |
| 18 | 查看详情显示文摘 | RAQUEL A MARIA J B LAURA C | | 0，，24： | 1 |
| 19 | Polycyclic aromatic hydrocarbons (PAHs) in two Spanish traditional smoked sausage varieties:'Androlla' and 'Botillo'显示文摘 | JOSE M L LAURA P MARIA C G F | | 0，，3： | 1 |
| 20 | Comorbidity and high viral load linked to clinical presentation of respiratory human bocavirus infection显示文摘 | Lucía María Ghietto Diego Majul Patricia Ferreyra Soaje Elsa Baumeister Martín Avaro Constanza Insfrán Liliana Mosca Alicia Cámara Laura Beatriz Moreno Maria Pilar Adamo | 2015 | Archives of Virology2015，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员