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| 1 | Intensive care organisation: Should there be a separate intensive care unit for critically injured patients?显示文摘In the last two decennia, the mixed population general intensive care unit(ICU) with a 'closed format' setting has gained in favour compared to the specialized critical care units with an 'open format' setting. However, there are still questions whether surgical patients benefit from a general mixed ICU. Trauma is a significant cause of morbidity and mortality throughout the world. Major or severe trauma requiring immediate surgical intervention and/or intensive care treatment. The role and type of the ICU has received very little attention in the literature when analyzing outcomes from critical injuries. Severely injured patients require the years of experience in complex trauma care that only a surgery/trauma ICU can provide. Should a trauma center have the capability of a separate specialized ICU for trauma patients('closed format') next to its standard general mixed ICU? | Tim K Timmers Michiel HJ Verhofstad Luke PH Leenen | 2015 | World Journal of Critical Care Medicine2015，4，3： | 1 |
| 2 | Operative or conserva- tive treatment in patients with Rockwood type III acromio- clavicular dislocation: a systematic review and update of current literature显示文摘 | Korsten K Gunning AC Leenen LP | 2014 | Int Orthop2014，38，4： | 1 |
| 3 | Quality of life and alexi-thymia in somatoform pain disorder显示文摘 | Garcia Nunez D Rufer M Leenen K | 2010 | Schmerz2010，24，1： | 1 |
| 4 | Heterogeneity of mouse spleen dendritic cells:in vivo phagocytic activity,expression of macrophage markers,and subpopulation turnover显示文摘 | Leenen PJ Radosevic K Voerman JS | 1998 | J Immunol1998，160，5： | 1 |
| 5 | Significantly higher number of fetal cells in the maternal circulation of women with pre - eclampsia 显示文摘 | Jansen MW Korver - Hakkennes K Van Leenen D | 2001 | Prenat Diagn2001，21，2： | 1 |
| 6 | Brain renin-angiotensin-aldosterone system and ventricular remodeling after myocardial infarct:a review显示文摘 | Westcott K V Huang B S Leenen F H | 2009 | Can J Physiol Pharmacol2009，87，12： | 1 |
| 7 | Characteristics and selection criteria for support materials for cell immobilization in wastewater treatment显示文摘 | Leenen E J Dos Santos V Grolle K | 1996 | Wat Res1996，30，12： | 1 |
| 8 | Heterogeneity of mouse spleen dendritic cells: in vivo phagocytic activity, ex- pression of macrophage makes,and subpopulation turn- over显示文摘 | Leenen P J Radosevic K Voerman J S Salomon B van Rooijen N Kiatzmann D | 1998 | J Immunol1998，160，： | 1 |
| 9 | Cause of death and time of death distribution oftrauma patients in a Level I trauma centre in the Netherlands显示文摘 | LANSINK K W W GUNNING A C LEENEN L PH | 2013 | Eur J Trauma Emerg Surg2013，39，： | 1 |
| 10 | Operative or conserva tive treatment in patients with Rockwood type Ill acromiocla- vicular disloeationa systematic review and update of current literature显示文摘 | Korsten K Gunning AC Leenen LP | 2014 | Int Orthop2014，38，83： | 1 |
| 11 | Characteristics of and selection criteria for support material for cell immobilization in wastewater treatment显示文摘 | Leenen E J T M Dos satos V A P Grolle K C F | 1996 | Water Research1996，30，12： | 1 |
| 12 | Heterogeneity of mouse spleen dendritic cells:in vivo phagocytic activity,expression of macrophage makers,and subpopulation turnover 显示文摘 | Leenen P J Radosevic K Voerman JS | 1998 | J Immunol1998，160，5： | 1 |
| 13 | Antitumor activity of protein kinase C inhibitors and cisplatin in human head and neck squamous cell carcinoma lines显示文摘 | Hoffmann TK Leenen K Hafner D | 2002 | Anti-cancer Drugs2002，13，1： | 1 |
| 14 | Operative or conservative treatment in patients with Rockwood typeⅢacromioclavicular dislocation:a systematic review and update of current literature显示文摘 | Korsten K Gunning AC Leenen LP | 2014 | Int Orthop2014，38，4： | 1 |
| 15 | Operative or conservative treatment in patients with Rockwood type Ⅲ acromioclavicular dislocation:a systematic review and update of current literature显示文摘 | Korsten K Gunning AC Leenen LP | | 0，，： | 1 |
| 16 | Characteristics of and selection criteria for support material for cell immobilization in wastewater treatment显示文摘 | Leenen E Santos V Grolle K | 1996 | Water Research1996，30，12： | 1 |
| 17 | Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms显示文摘 | van der Horst GT Muijtjens M Kobayashi K Takano R Kanno S Takao M de Wit J Verkerk A Eker AP van Leenen D Buijs R Bootsma D Hoeijmakers JH Yasui A | | 0，，6728： | 1 |
| 18 | Operative or conservative treatment in patients with Rockwood type Ⅲ acromioclavicular dislocation systematic review and update of current literature显示文摘 | Korsten K Gunning AC Leenen LP | 2014 | Int Orthop2014，38，4： | 1 |
| 19 | Visceral fat loss measured by magnetic resonance imaging in relation to changes in scrum lipid levels of obese men and woman显示文摘 | Leenen R Van der Kooy K Droop A | 1993 | Arterioscler Thromb1993，13，4： | 1 |
| 20 | Intensive care performance: How should we monitor performance in the future?显示文摘Intensive care faces economic challenges. Therefore, evidence proving both effectiveness and efficiency, i.e., cost-effectiveness, of delivered care is needed. Today, the quality of care is an important issue in the health care debate. How do we measure quality of care and how accurate and representative is this measurement? In the following report, several topics which are used for the evaluation of intensive care unit(ICU) performance are discussed:(1) The use of general outcome prediction models to determine the risk of patients who are admitted to ICUs in an increasing variety of case mix for the different intensive care units, together with three major limitations;(2) As critical care outcomes research becomes a more established entity, mortality is now only one of many endpoints that are relevant. Mortality is a limited outcome when assessing critical care performance, while patient interest in quality of life outcomes is relevant; and(3) The Quality Indicators Committee of the Society of Critical Care Medicine recommended that short-term readmission is a major performance indicator of the quality of intensive care medicine. | Tim K Timmers Michiel HJ Verhofstad Karl GM Moons Luke PH Leenen | 2014 | World Journal of Critical Care Medicine2014，3，4： | 1 |
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