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| 1 | PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix显示文摘Biofilms 是在细胞外的矩阵嵌入的微生物的联系表面的社区。Exopolysaccharide 是在维持 biofilm 建筑学并且保护居民 biofilm 细菌免受抗菌剂和主人免疫者攻击的伤害的细胞外的矩阵的一个批评部件。然而,指向矩阵 exopolysaccharides 的自我生产的因素,仍然糟糕被理解。这里,我们显示出那 PslG,在 Pseudomonas aeruginosa 涉及关键 biofilm 矩阵 exopolysaccharide Psl 的合成的蛋白质,阻止 biofilm 形成并且拆卸存在在外长地供应的在 nanomolar 集中的分钟以内的 biofilms。PslG 的水晶结构显示 endoglycosidase 的典型特征。PslG 主要破坏 Psl 矩阵从 biofilms 驱散细菌。PslG 处理显著地提高 biofilm 敏感到抗菌素和巨噬细胞房间,导致在一只老鼠的改进 biofilm 清理植入感染模型。而且, PslG 对大量 Pseudomonas 种类显示出 biofilm 抑制和拆卸活动,显示它在与 biofilm 相关的复杂并发症作斗争的大潜力。 | Shan Yu Tiantian Su Huijun Wu Shiheng Liu Di Wang Tianhu Zhao Zengjun Jin Wenbin Du Mei-Jun Zhu Song Lin Chua Liang Yang Deyu Zhu Lichuan Gu Luyan Z Ma | 2015 | Cell Research2015，25，12： | 13 |
| 2 | Value of diffusion-weighted imaging in distinguishing pancreatic carcinoma from mass-forming chronic pancreatitis: a meta-analysis显示文摘 | Niu Xiangke Sushant Kumar Das Anup Bhetuwal Xiao Yingquan Sun Feng Zeng Lichuan Wang Wenxuan Yang Hanfeng Yang Hanyu | 2014 | Chinese Medical Journal2014，，19： | 11 |
| 3 | Feed-Forward Active Noise Control System Using Microphone Array显示文摘Feedforward active noise control(ANC) system are widely used to reduce the wide-band noise in different application. In feedforward ANC systems, when the noise source is unknown, the misplacement of the reference microphone may violate the causality constraint. We present a performance analysis of the feedforward ANC system under a noncausal condition. The ANC system performance degrades when the degree of noncausality increases. This research applies the microphone array technique to feedforward ANC systems to solve the unknown noise source problem. The generalized cross-correlation(GCC) and steering response power(SRP) methods based on microphone array are used to estimate the noise source location.Then, the ANC system selects the proper reference microphone for a noise control algorithm. The simulation and experiment results show that the SRP method can estimate the noise source direction with 84% accuracy. The proposed microphone array integrated ANC system can dramatically improve the system performance. | Yang Li Lichuan Liu Sen M. Kuo | 2018 | IEEE/CAA Journal of Automatica Sinica2018，5，5： | 3 |
| 4 | A sensitivity study of the WRF model in offshore wind modeling over the Baltic Sea显示文摘Accurate wind modeling is important for wind resources assessment and wind power forecasting. To improve the WRF model configuration for the offshore wind modeling over the Baltic Sea, this study performed a sensitivity study of the WRF model to multiple model configurations, including domain setup,grid resolution, sea surface temperature, land surface data, and atmosphere-wave coupling. The simulated offshore wind was evaluated against LiDAR observations under different wind directions, atmospheric stabilities, and sea status. Generally, the simulated wind profiles matched observations, despite systematic underestimations. Strengthening the forcing from the reanalysis data through reducing the number of nested domains played the largest role in improving wind modeling. Atmosphere-wave coupling further improved the simulated wind, especially under the growing and mature sea conditions.Increasing the vertical resolution, and updating the sea surface temperature and the land surface information only had a slight impact, mainly visible during very stable conditions. Increasing the horizontal resolution also only had a slight impact, most visible during unstable conditions. Our study can help to improve the wind resources assessment and wind power forecasting over the Baltic Sea. | Huidong Li Björn Claremar Lichuan Wu Christoffer Hallgren Heiner Körnich Stefan Ivanell Erik Sahlée | 2021 | Geoscience Frontiers2021，12，6： | 2 |
| 5 | Tea picking point detection and location based on Mask-RCNN显示文摘The accurate identification,detection,and segmentation of tea buds and leaves are important factors for realizing intelligent tea picking.A tea picking point location method based on the region-based convolutional neural network(R-CNN)Mask-RCNN is proposed,and a tea bud and leaf and picking point recognition model is established.First,tea buds and leaf pictures are collected in a complex environment,the Resnet50 residual network and a feature pyramid network(FPN)are used to extract bud and leaf features,and preliminary classification and preselection box regression training-performed on the feature maps through a regional proposal network(RPN).Second,the regional feature aggregation method(RoIAlign)is used to eliminate the quantization error,and the feature map of the preselected region of interest(ROI)is converted into a fixed-size feature map.The output module of the model realizes the functions of classification,regression and segmentation.Finally,through the output mask image and the positioning algorithm the positioning of the picking points of tea buds and leaves is determined.One hundred tea tree bud and leaf pictures in a complex environment are selected for testing.The experimental results show that the average detection accuracy rate reaches 93.95%and that the recall rate reaches 92.48%.The tea picking location method presented in this paper is more versatile and robust in complex environments. | Tao Wang Kunming Zhang Wu Zhang Ruiqing Wang Shengmin Wan Yuan Rao Zhaohui Jiang Lichuan Gu | 2023 | Information Processing in Agriculture2023，10，2： | 2 |
| 6 | Design and implementation of an active rectangular aerostatic thrust bearing stage with electromagnetic actuators显示文摘The design and implementation of an active rectangular aerostatic thrust bearing stage with electro-magnetic actuators are presented. The stage is fundamentally precise and simple since the out-of-plane degree-of-freedoms (DOF) of a thrust air bearing are closed-loop controlled by electromagnetic actua-tors. The design is one-moving-part with mechanical symmetry, and a commercially available air bear-ing is rigidly attached to the table. The actuators are four independent coils mounted to the guiding surface of the table with iron cores, which are directly machined on the table. A bench level prototype system is developed and out-of-plane axes decoupled models of the system are derived. A control al-gorithm synthesized by arbitrarily placing closed-loop poles according to the model with air bearing dynamics neglected is implemented by C programming language running on the DOS platform. The stage is capable of vertical direction precision micro-positioning and guiding 3-DOF plane motions without limiting the working range of plane motions. Positioning accuracy of the stage no longer de-pends upon design and manufacturing of an air bearing, while passive preload of the stage for a flat film aerostatic thrust bearing is eliminated. | MAO JunHong LI LiChuan | 2009 | Chinese Science Bulletin2009，54，5： | 2 |
| 7 | The effect of hydrogen-bond in alcoholic solvent on the solvation ultrafast dynamics of oxazine 750 dye显示文摘The ultrafast dynamics of oxazine 750 dye was studied in methanol,ethanol,1-propanol,1-butanol solvents using the femtosecond time-resolved stimulated emission pumping fluorescence depletion (FS TR SEP FD) technique. The faster decays on the hundreds of femtosecond time scale and the slower decays on the order of picosecond were found. The intramolecular vibrational redistribution (IVR) and the solute-solvent intermolecular photoinduced electron transfer (ET) should account for the faster decay,while the slower decay is attributable to the diffusive solvent relaxation. The results show that the intermolecular hydrogen-bonding network will hinder the rearrangement of the alcoholic molecules in the solvation process and the time constants of the slower diffusive solvent relaxation decays are found to increase with the hydrogen-bonding energy in alcoholic solvents. | ZHOU LiChuan SHI Ying LIU JianYong HAN KeLi | 2008 | Chinese Science Bulletin2008，53，13： | 2 |
| 8 | Throttle characteristics of multi-stage circumfluence nozzle during the separate-layer injection of CO_(2)显示文摘Separate-layer injection of CO2 is an important method to improve oil and gas production and recovery.Conventional single-stage nozzle is usually blocked by impurities,and the ice-barrier phenomenon is very common.To solve this problem,large-diameter multi-stage circumfluence nozzle was designed to release pressure stage by stage.In order to illuminate the throttle characteristics of the CO2 multi-stage circumfluence nozzles,numerical simulation was performed to test several nozzles with different diameters and stage numbers.Furthermore,we tested the throttle characteristics through laboratory experiments and obtained the effects of several critical parameters such as nozzle diameter,number of stage and pressure drop on the throttle characteristics.The results show that the flow rate decreases as the nozzle stage increases on the condition of constant pressure and nozzle diameter.And pressure difference increases as nozzle stage number increases under the constant flow rate.The throttle capability of multi-stage circumfluence nozzles was much better than the concentric nozzles.Large-diameter multi-stage nozzle is recommended rather than small-diameter single-stage nozzle during the process of separate-layer injection,which can efficiently prevent impurities and ice blocking.The results are expected to provide a theoretical support for the nozzle choice of separate-layer injection of CO2. | Haizhu Wang Gensheng Li Lichuan Zhao Youwen Wang Yun Liu Qingling Liu Meng Wang Fei Gao Meng Cai | 2018 | Petroleum2018，4，2： | 2 |
| 9 | NATURAL FREQUENCY OF COMPONENT UNDER INFLUENCE OF WELDING RESIDUAL STRESS显示文摘According to the distribution feature of welding residual stress on plate with welding seam along axis,a mathematical model of the welding residual stress is established.A formula of natural frequency of four boundary simply-supported quadrate thin plate with welding residual stress is developed.Some conclusions have been obtained.They are:(1)if there is welding residual stress,all natural frequencies of component are in increase,(2)change of high rank natural frequency under the influence of residual stress is larger than that of low rank natural frequency,and the higher the rank number is the larger the absolute amount of change of natural frequency is. | Gao Yongyi Lin Lichuan | 1996 | Transactions of Nonferrous Metals Society of China1996，6，1： | 2 |
| 10 | Metallogenic controls on the granite-related W–Sn deposits in the Hunan–Jiangxi region, China: evidence from zircon trace element geochemistry显示文摘The Nanling Range in South China is well known for its rich granite-related W–Sn deposits.To elucidate the controls of different granite-related W–Sn metallogenesis in the region,we chose five representative orerelated granites(Yanbei,Mikengshan,Tieshanlong,Qianlishan,and Yaogangxian intrusions)in the Hunan–Jiangxi region,and studied their magmatic zircon ages and trace element geochemistry.Our new zircon data showed the differences in ages,temperatures and oxygen fugacity of the ore-forming magmas.Zircon U–Pb ages of the Yanbei and Mikengshan intrusions are characterized by 142.4±2.4 and 143.0±2.3 Ma,respectively,whereas the Tieshanlong and Qianlishan intrusions are 159.5±2.3and 153.2±3.3 Ma,respectively.The Sn-related intrusions were younger than the W-related intrusions.The Tiin-zircon thermometry showed that there was no systematic difference between the Sn-related Yanbei(680–744℃)and Mikengshan(697–763℃)intrusions and the W-related Tieshanlong(730–800℃),Qianlishan(690–755℃)and Yaogangxian(686–751℃)intrusions.However,the zircon Ce^4+/Ce^3+ratios of the Yanbei(averaged at 18.3)and Mikengshan(averaged at 18.8)intrusions are lower than those of the Tieshanlong(averaged at 36.9),Qianlishan(averaged at 38.4)and Yaogangxian(averaged at 37)intrusions,indicating that the Sn-related granitic magmas might have lower oxygen fugacities than those of the W-related.This can be explained by that,in more reduced magmas,Sn is more soluble than W and thus is more enriched in the residual melt to form Sn mineralization.The difference in source materials between the Sn-related and the W-related granites seems to have contributed to the different redox conditions of the melts. | Yuannan Feng Tingguang Lan Lichuan Pan Tingting Liu Shaohua Dong | 2019 | Acta Geochimica2019，38，4： | 2 |
| 11 | Integration of Communication and Computing in Blockchain-Enabled Multi-Access Edge Computing Systems显示文摘Blockchain and multi-access edge com-puting(MEC)are two emerging promising tech-nologies that have received extensive attention from academia and industry.As a brand-new information storage,dissemination and management mechanism,blockchain technology achieves the reliable transmis-sion of data and value.While as a new computing paradigm,multi-access edge computing enables the high-frequency interaction and real-time transmission of data.The integration of communication and com-puting in blockchain-enabled multi-access edge com-puting networks has been studied without a systemat-ical view.In the survey,we focus on the integration of communication and computing,explores the mu-tual empowerment and mutual promotion effects be-tween the blockchain and MEC,and introduces the resource integration architecture of blockchain and multi-access edge computing.Then,the paper sum-marizes the applications of the resource integration ar-chitecture,resource management,data sharing,incen-tive mechanism,and consensus mechanism,and ana-lyzes corresponding applications in real-world scenar-ios.Finally,future challenges and potentially promis-ing research directions are discussed and present in de-tail. | Zhonghua Zhang Jie Feng Qingqi Pei Le Wang Lichuan Ma | 2021 | China Communications2021，18，12： | 2 |
| 12 | Multi-objective optimization of frequency and damping of vertical stabilizer skin structure placed with variable-angle tows显示文摘The vibration characteristics of composite vertical stabilizer skin structures play a critical role in damping effects designed for overcoming the air disturbances experienced by aircraft structural components during flight.The first-order fundamental frequencies and their corresponding damping characteristics of the vertical stabilizer skin structure tow-steered by automatic fiber placement technique were optimized with the parameterized trajectories and plies as design variables.Firstly,the vibration and damping numerical models were derived based on Kirchhoff laminate theory,the Rayleigh-Ritz method,and the Strain Energy Method.Then the optimization model was developed by adopting the self-adaptive Differential Evolution Multi-objective optimization algorithm and incorporating the solution method of Pareto Front.The constraints of this optimization model considered the experimentally obtained minimum turning radius of prepregs tow-steered in automatic fiber placement process obtained from experimental tests.Finally,the comparison of numerical simulation results was conducted for the optimized trajectories and the conventional straight trajectories under various boundary conditions,and the numerical results were partially validated through damping and frequency tests.The results indicate the vibration characteristics of the composite vertical stabilizer skin structure can be enhanced to a large extent by optimizing fiber trajectories,and the enhancement percentage is affected by the boundary conditions of the actual structure. | Lei ZU Xianzhao XIA Qian ZHANG Guiming ZHANG Shijun CHEN Jianhui FU Lichuan ZHOU Huabi WANG Debao LI Liqing ZOU | 2023 | Chinese Journal of Aeronautics2023，36，1： | 1 |
| 13 | GMM parameter estimation based on split EM algorithm显示文摘 | ZHONG Jinqin GU Lichuan TAN Jieqing | 2012 | Computer Engineering and Application2012，48，34： | 1 |
| 14 | Application of QUAL2Kw model to simulation of water quali-ty in Huangshan section of Xin an River显示文摘 | ZIIAOGang(赵翌) LIChuan(李川) LUYuchao(陆宁超) etal | 2013 | 水资源与水下程学报2013，24，5： | 1 |
| 15 | 显示文摘 | Ko T H Huang Lichuan | 1998 | Journal of Applied Polymer Science1998，70，： | 1 |
| 16 | Soybean Protein Agglomeration: Promotion by Ul- trasonic Treatment显示文摘 | Wang Lichuan | 1981 | Journal of Agricultural and Food Chemistry1981，29，： | 1 |
| 17 | Expression of P-gp, MRP, LRP, GST-π and TopoIIα and intrinsic resistancein human lung cancer cell lines显示文摘 | Jiarui Wang Jinhui Zhang Lichuan Zhang Long Zhao Sufang Fan Zhonghai Yang Fei Gao Ying Kong Gary Xiao Qi Wang | 2011 | Oncology Reports2011，，5： | 1 |
| 18 | Linearizing magnetic bearing actuators by constant current sum, constant voltage sum, and constant flux sum显示文摘 | Li Lichuan | 1999 | IEEE Transactions on Magnetics1999，35，1： | 1 |
| 19 | Therapeutic effects of coenzyme Q10 and reduced CoQ10 in the MPTP model of Parkinsonism显示文摘 | Cleren Carine Yang Lichuan Lorenzo Beverly | 2008 | Journal of Neurochemistry2008，104，6： | 1 |
| 20 | Molecular evolution of two duplicated CDPK genes CPK7 and CPK12 in grass species: A case study in wheat ( Triticum aestivum L.)显示文摘 | Shuaifeng Geng Yongliang Zhao Lichuan Tang Rongzhi Zhang Minghui Sun Hanzi Guo Xiuying Kong Aili Li Long Mao | 2011 | Gene2011，，2： | 1 |
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