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| 1 | Transcriptional regulation of oil biosynthesis inseed plants: Current understanding, applications,and perspectives显示文摘Plants produce and accumulate triacylglycerol(TAG)in their seeds as an energy reservoir to support the processes of seed germination and seedling development.Plant seed oils are vital not only for the human diet but also as renewable feedstocks for industrial use.TAG biosynthesis consists of two major steps:de novo fatty acid biosynthesis in the plastids and TAG assembly in the endoplasmic reticulum.The latest advances in unraveling transcriptional regulation have shed light on the molecular mechanisms of plant oil biosynthesis.We summarize recent progress in understanding the regulatory mechanisms of wellcharacterized and newly discovered transcription factors and other types of regulators that control plant fatty acid biosynthesis.The emerging picture shows that plant oil biosynthesis responds to developmental and environmental cues that stimulate a network of interacting transcriptional activators and repressors,which in turn fine-tune the spatiotemporal regulation of the pathway genes. | Yuzhou Yang Que Kong Audrey R.Q.Lim Shaoping Lu Hu Zhao Liang Guo Ling Yuan Wei Ma | 2022 | Plant Communications2022，3，5： | 2 |
| 2 | Tolerance of neurite outgrowth to Rho kinase inhibitors decreased by cyclooxygenase-2 inhibitor显示文摘In this study, PC12 Adh cells and Neuro-2a cells were treated with Rho-associated kinase inhibitors (Y27632 and Fasudil), a cyclooxygenase-1 selective inhibitor (SC560), and a cyclooxygenase-2 inhibitor (NS398). We found that these cells became tolerant to Rho-associated kinase inhibitors, as neurite outgrowth induced by these inhibitors diminished following more than 3 days of exposure in either cell line. The proteins cyclooxygenase-2 and cytosolic prostaglandin E synthetase were upregulated at day 3. NS398 decreased the tolerance to neurite outgrowth induction in both cell lines, whereas SC560 had almost no effect. These findings indicate that cells become tolerant to neurite outgrowth induced by Rho-associated kinase inhibitors, this is at least partly associated with upregulation of proteins involved in the cyclooxygenase-2 pathway, and cyclooxygenases-2 inhibition prevents this tolerance. | Weigang Duan Ling Que Xiaoman Lv Qifeng Li Hua Yin Luyong Zhang | 2012 | Neural Regeneration Research2012，7，34： | 1 |
| 3 | Isolation and functional characterization of a floral tissue-specific R2R3 MYB regulator from tobacco显示文摘 | Sitakanta Pattanaik Que Kong David Zaitlin Joshua R. Werkman Claire H. Xie Barunava Patra Ling Yuan | 2010 | Planta2010，，5： | 1 |
| 4 | Genetic and physical mapping of Pi37(t), a new gene conferring resistance to rice blast in the famous cultivar St. No. 1显示文摘 | Shen Chen Ling Wang Zhiquen Que Ruqian Pan Qinghua Pan | 2005 | Theoretical and Applied Genetics2005，，8： | 1 |
| 5 | Genetic and physical mapping of Pi37(t), a new gene conferring resistance to rice blast in the famous cultivar St. No. 1显示文摘 | Shen Chen Ling Wang Zhiquen Que Ruqian Pan Qinghua Pan | 2005 | Theoretical and Applied Genetics2005，，8： | 1 |
| 6 | Oxygen-assisted preparation of mechanoluminescent ZnS:Mn for dynamic pressure mapping显示文摘变换机械刺激点亮排放的 Mechanoluminescent 材料在人机器的相互作用为潜在的应用吸引了广泛的注意。这里,我们为 ZnS 的帮助氧的准备报导一条简单、可得到的新奇途径: Mn 粒子由固态在没有相应氧化物的形成的气压的反应。O 2 的存在在 wurtzite 阶段 ZnS 在 S 空缺的形成上有积极影响,导致 Mn 2+ 离子的介绍光中心和浅施主铺平,它能改进电子洞再结合率。O 2 比率和 Mn 2+ 离子做集中在发光效率上有重要效果,它分别地在 1%-20% 和 1 at.%-2 at.% 是最佳的。另外,一台设备基于有 0.032 MPa 1 的优秀压力敏感的 piezo-photonic 效果被制作,它能印射在 situ 从 2.2 ~ 40.6 MPa 的二维的压力分发。这台设备能被用于即时压力印射,聪明的传感器网络,高级安全系统,人机器的接口,和人工的皮肤。 | Xiandi Wang Rui Ling Yufei Zhang Miaoling Que Yiyao Peng Caofeng Pan | 2018 | Nano Research2018，11，4： | 1 |
| 7 | Overexpression of a sugarcane ScCaM gene negatively regulates salinity and drought stress responses in transgenic Arabidopsis thaliana显示文摘Calmodulin(CaM)proteins play a key role in signal transduction under various stresses.In the present study,the effects of a sugarcane ScCaM gene(NCBI accession number:GQ246454)on drought and salt stress tolerance in transgenic Arabidopsis thaliana and Escherichia coli cells were evaluated.The results demonstrated a significant negative role of ScCaM in the drought and salt stress tolerance of transgenic lines of A.thaliana,as indicated by the phenotypes.In addition,the expression of AtP5CS and AtRD29A,two genes tightly related to stress resistance,was significantly lower in the overexpression lines than in the wild type.The growth of E.coli BL21 cells expressing ScCaM showed weaker tolerance under mannitol and NaCl stress.Taken together,this study revealed that the ScCaM gene plays a negative regulatory role in both mannitol and NaCl stresses,and it possibly exerts protective mechanisms common in both prokaryotes and eukaryotes under stress conditions. | JINXIAN LIU JINGFANG FENG CHANG ZHANG YONGJUAN REN WEIHUA SU GUANGHENG WU XIANYU FU NING HUANG YOUXIONG QUE HUI LING JUN LUO | 2023 | BIOCELL2023，47，1： | 0 |
| 8 | Role of surgical treatments in high-grade or advanced gastroenteropancreatic neuroendocrine neoplasms显示文摘Over the last 40 years,the incidence and prevalence of gastroenteropancreatic neuroendocrine neoplasms(GEP-NENs)have continued to increase.Compared to other epithelial neoplasms in the same organ,GEP-NENs exhibit indolent biological behavior,resulting in more chances to undergo surgery.However,the role of surgery in high-grade or advanced GEP-NENs is still controversial.Surgery is associated with survival improvement of well-differentiated highgrade GEP-NENs,whereas poorly differentiated GEP-NENs that may benefit from resection require careful selection based on Ki67 and other tissue biomarkers.Additionally,surgery also plays an important role in locally advanced and metastatic disease.For locally advanced GEP-NENs,isolated major vascular involvement is no longer an absolute contraindication.In the setting of metastatic GEP-NENs,radical intended surgery is recommended for patients with low-grade and resectable metastases.For unresectable metastatic disease,a variety of surgical approaches,including cytoreduction of liver metastasis,liver transplantation,and surgery after neoadjuvant treatment,show survival benefits.Primary tumor resection in GEP-NENs with unresectable metastatic disease is associated with symptom control,prolonged survival,and improved sensitivity toward systemic therapies.Although there is no established neoadjuvant or adjuvant strategy,increasing attention has been given to this emerging research area.Some studies have reported that neoadjuvant therapy effectively reduces tumor burden,improves the effectiveness of subsequent surgery,and decreases surgical complications. | Qing-Yang Que Lin-Cheng Zhang Jia-Qi Bao Sun-Bin Ling Xiao Xu | 2022 | World Journal of Gastrointestinal Surgery2022，14，5： | 0 |
| 9 | Peutz-Jeghers syndrome: a report of 5 cases显示文摘Peutz-Jeghers syndrome (PJS), also known as hereditary intestinal polyposis syndrome, is an autosomal dominant genetic disease characterized by the development of benign hamartomatous polyps in the gastrointestinal tract and hyperpigmented macules on the lips and oral mucosa. Here, we reported 5 cases of PJS and our experience about its diagnosis and treatment. | Wang Xingwei Fan Chaoqiang Que Dan Guo Hong Wang Lei Ling Xianlong Deng Lei Zhao Xiaoyan | 2011 | Journal of Medical Colleges of PLA(China)2011，26，4： | 0 |
| 10 | CAS and CEA in the Treatment of Severe Internal Carotid Artery Stenosis显示文摘Objective:To explore the clinical value of carotid artery stent implantation(CAS)and carotid endarterectomy(CEA)in the treatment of patients with severe internal carotid artery stenosis.Methods:88 patients with severe carotid artery stenosis who underwent CAS and CEA in the First People's Hospital of Changde City(hereafter referred as 'our hospital')from January 2018 to December 2020 were selected as the research objects and divided into CAS group(n=43)and CEA group(n=45).To understand the clinical application value and feasibility of the two surgical schemes by comparing the general situation,cerebral blood flow,MMSE scale,MOCA scale score and serum miR-145,IGF1R levels of the two surgical schemes.Conclusions:CAS and CEA in the treatment of patients with severe internal carotid artery stenosis,have good curative effect,can effectively improve the patient's cerebral blood flow,regulate serum miR-145,IGF 1R levels,promote the recovery of cognitive function,but relatively speaking,the incidence of stroke and hypotension after CAS is higher,and the incidence of hypertension after CEA is higher. | Ling Yao Jing Yi Lixin Xu Jun Wen Siwei Que | 2021 | Journal of Clinical and Nursing Research2021，5，4： | 0 |
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