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25篇 您的检索式:作者名="Linjie Zhao"
    题名 作者 年代 出处 被引量
1Formation mechanism of a smooth, defectfree surface of fused silica optics using rapid CO2 laser polishing显示文摘Surface defects introduced by conventional mechanical processing methods can induce irreversible damage and reduce the service life of optics applied in high-power lasers.Compared to mechanical processing,laser polishing with moving beam spot is a noncontact processing method,which is able to form a defect-free surface.This work aims to explore the mechanism of forming a smooth,defect-free fused silica surface by high-power density laser polishing with coupled multiple beams.The underlying mechanisms of laser polishing was revealed by numerical simulations and the theoretical results were verified by experiments.The simulated polishing depth and machined surface morphology were in close agreement with the experimental results.To obtain the optimized polishing quality,the effects of laser polishing parameters(e.g.overlap rate,pulse width and polishing times)on the polishing quality were experimentally investigated.It was found that the processing efficiency of fused silica materials by carbon dioxide(CO2)laser polishing could reach 8.68 mm2 s−1,and the surface roughness(Ra)was better than 25 nm.Besides,the cracks on pristine fused silica surfaces introduced by initial grinding process were completely removed by laser polishing to achieve a defect-free surface.The maximum laser polishing rate can reach 3.88μm s−1,much higher than that of the traditional mechanical polishing methods.The rapid CO2 laser polishing can effectively achieve smooth,defect-free surface,which is of great significance to improve the surface quality of fused silica optics applied in high-power laser facilities.Linjie Zhao Jian Cheng Mingjun Chen Xiaodong Yuan Wei Liao Qi Liu Hao Yang Haijun Wang 2019International Journal of Extreme Manufacturing2019,1,3:8
216 × 16 silicon Mach–Zehnder interferometer switch actuated with waveguide microheaters显示文摘We experimentally demonstrate a 16 × 16 reconfigurably nonblocking optical switch fabric using a Benes architecture. The switch fabric consists of 56 2 × 2 Mach–Zehnder interferometer based elementary switches, with each integrated with a pair of waveguide microheaters. The average on-chip insertion loss is ~5.2 dB for both of the 'all-cross' and the 'all-bar' states, with a loss variation of 1 dB over all routing paths. The cross talk for all switching states is better than -30 d B. The switching time of the switch element is about 22 μs. The switching functionality is verified by transmission of a 40 Gb∕s quadrature phase-shift keying optical signal.Shuoyi Zhao Liangjun Lu Linjie Zhou Dong Li Zhanzhi Guo Jianping Chen 2016Photonics Research2016,4,5:7
3Molecular Framework for Auxin-Controlled Hlomeostasis-of Shoot Stem Cells in Arabidopsis显示文摘Linjie Luo Jian Zengg Haijun Wu Zhaoxia Tian Zhong Zhao 2018Molecular Plant2018,11,7:7
4Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions显示文摘Brain tumors are dynamic complex ecosystems with multiple cell types.To model the brain tumor microenvironment in a reproducible and scalable system,we developed a rapid three-dimensional(3D)bioprinting method to construct clinically relevant biomimetic tissue models.In recurrent glioblastoma,macrophages/microglia prominently contribute to the tumor mass.To parse the function of macrophages in 3D,we compared the growth of glioblastoma stem cells(GSCs)alone or with astrocytes and neural precursor cells in a hyaluronic acid-rich hydrogel,with or without macrophage.Bioprinted constructs integrating macrophage recapitulate patient-derived transcriptional profiles predictive of patient survival,maintenance of stemness,invasion,and drug resistance.Whole-genome CRISPR screening with bioprinted complex systems identified unique molecular dependencies in GSCs,relative to sphere culture.Multicellular bioprinted models serve as a scalable and physiologic platform to interrogate drug sensitivity,cellular crosstalk,invasion,context-specific functional dependencies,as well as immunologic interactions in a species-matched neural environment.Min Tang Qi Xie Ryan C.Gimple Zheng Zhong Trevor Tam Jing Tian Reilly L.Kidwell Qiulian Wu Briana C.Prager Zhixin Qiu Aaron Yu Zhe Zhu Pinar Mesci Hui Jing Jacob Schimelman Pengrui Wang Derrick Lee Michael H.Lorenzini Deobrat Dixit Linjie Zhao Shruti B.hargava Tyler E.Miller Xueyi Wan Jing Tang Bingjie Sun Benjamin F.Cravatt Alysson R.Muotri Shaochen Chen Jeremy N.Rich 2020Cell Research2020,30,10:6
54×4 nonblocking optical switch fabric based on cascaded multimode interferometers显示文摘We experimentally demonstrate a 4 × 4 nonblocking silicon thermo-optic(TO) switch fabric consisting of three stages of tunable generalized Mach–Zehnder interferometers. All 24 routing states for nonblocking switching are characterized. The device's footprint is 4.6 mm × 1.0 mm. Measurements show that the worst cross talk of all switching states is-7.2 dB. The on-chip insertion loss is in the range of 3.7–13.1 dB. The average TO switching power consumption is 104.8 mW.Zuxiang Li Linjie Zhou Liangjun Lu Shuoyi Zhao Dong Li Jianping Chen 2016Photonics Research2016,4,1:2
6Seasonal dynamics of soil water content in the typical vegetation and its response to precipitation in a semi-arid area of Chinese Loess Plateau显示文摘Soil water content is a key limiting factor for vegetation growth in the semi-arid area of Chinese Loess Plateau and precipitation is the main source of soil water content in this area.To further understand the impact of vegetation types and environmental factors such as precipitation on soil water content,we continuously monitored the seasonal dynamics in soil water content in four plots(natural grassland,Caragana korshinskii,Armeniaca sibirica and Pinus tabulaeformis)in Chinese Loess Plateau.The results show that the amplitude of soil water content fluctuation decreases with an increase in soil depth,showing obvious seasonal variations.Soil water content of artificial vegetation was found to be significantly lower than that of natural grassland,and most precipitation events have difficulty replenishing soil water content below a depth of 40 cm.Spring and autumn are the key seasons for replenishment of soil water by precipitation.Changes in soil water content are affected by precipitation,vegetation types,soil evaporation and other factors.The interception effect of vegetation on precipitation and the demand for water consumption by transpiration are the key factors affecting the efficiency of soil water replenishment by precipitation in this area.Due to artificial vegetation plantation in this area,soil will face a water deficit crisis in the future.ZHOU Tairan HAN Chun QIAO Linjie REN Chaojie WEN Tao ZHAO Changming 2021Journal of Arid Land2021,13,10:2
7Autophagy in tumorigenesis and cancer therapy 显示文摘Shengtao Zhou Linjie Zhao Manchao Kuang 2012Cancer Letters2012,323,1:1
8Online hy- drophobicity measurement for silicone rubber insulators on transmission lines 显示文摘Zhao Linjie Li Chengrong Xiong Jun 2009IEEE Transactions on Power De- livery2009,24,2:1
9Synthesis of no- volac/layered silicate nanocomposites by reaction exfoliation using acid-modified montmorilionite 显示文摘Wang Hongsheng Zhao Tong Zhi Linjie 2002Macromol Rapid Commun2002,23,:1
10Preparation of Phenolic Resin/Silver Nanocomposites via In-situ Reduction 显示文摘Linjie Zhi Tong Zhao Yun Zhao Yu 2002Scripta Materialia2002,47,12:1
11CVD synthesis of nitrogen-doped graphene using urea显示文摘This work provides an effective low-cost synthesis and in-depth mechanistic study of high quality large-area nitrogen-doped graphene(NG) films. These films were synthesized using urea as nitrogen source and methane as carbon source, and were characterized by scanning electron microscopy(SEM), Raman spectroscopy and X-ray photoelectron spectroscopy(XPS). The N doping level was determined to be 3.72 at.%, and N atoms were suggested to mainly incorporated in a pyrrolic N configuration. All distinct Raman peaks display a shift due to the nitrogen-doping and compressive strain. The increase in urea concentration broadens the D and 2D peak's Full Width at Half Maximum(FWHM), due to the decrease of mean free path of phonons. The N-doped graphene exhibited an n-type doping behavior with a considerably high carrier mobility of about 74.1 cm2/(V s), confirmed by electrical transport measurements.ZHANG CanKun LIN WeiYi ZHAO ZhiJuan ZHUANG PingPing ZHAN LinJie ZHOU YingHui CAI WeiWei 2015Science China(Physics,Mechanics & Astronomy)2015,58,10:1
12Influence of sea- sons on hydrophobicity of silicone rubber insulators in semi-wet warm-temperature zone of china显示文摘Li Chengrong Zhao Linjie Xiong Jun 2008IEEE Transactions on Di- electrics and Electrical Insulation2008,15,4:1
13The effect of umbrella-type branching on the blood circulation and tumor targeting of star-branched PLA-PMPC copolymer micelles显示文摘The effect of branching on the blood circulation and tumor targeting of polymer nanovehicles in vivo was investigated in this study. For the purpose, star-branched poly(lactic acid) and poly(2-methacryloyloxyethyl phosphorylcholine)(PLA-PMPC)copolymers with umbrella-type AB3,(AB3)_(2), and(AB3)_(3) architecture were synthesized by branching at the PLA core. Micelles self-assembled from these copolymers were used to evaluate the effect of core branching on blood circulation and tumor targeting. The results showed that branching changed the behavior of polymeric self-assembly in solution, thereby changing the size and surface anti-fouling performance of the polymeric micelles. Moreover, star-branched copolymer micelles with a higher branching degree allowed their payload to persist better in blood(half-time prolonged from 7.1, 8.6 to 13.8 h) and for a 1.72-fold higher content at the tumor site. These studies suggest that raising the branching degree of amphiphilic copolymer potentially offers a promising strategy for the design of carriers capable of enhanced circulation and targeting in vivo.LONG LiXia CHENG LinJie HOU JingJing WANG LiMei WANG Xu HE LiGang LI SiDi ZHAO Jin HOU Xin KANG ChunSheng YUAN XuBo 2021Science China(Technological Sciences)2021,64,1:0
14Self-Assembled Porous-Reinforcement Microstructure-Based Flexible Triboelectric Patch for Remote Healthcare显示文摘Realizing real-time monitoring of physiological signals is vital for preventing and treating chronic diseases in elderly individuals. However,wearable sensors with low power consumption and high sensitivity to both weak physiological signals and large mechanical stimuli remain challenges.Here, a flexible triboelectric patch(FTEP) based on porous-reinforcement microstructures for remote health monitoring has been reported. The porousreinforcement microstructure is constructed by the self-assembly of silicone rubber adhering to the porous framework of the PU sponge. The mechanical properties of the FTEP can be regulated by the concentrations of silicone rubber dilution. For pressure sensing, its sensitivity can be effectively improved fivefold compared to the device with a solid dielectric layer, reaching 5.93 kPa^(-1) under a pressure range of 0–5 kPa. In addition, the FTEP has a wide detection range up to 50 kPa with a sensitivity of 0.21 kPa^(-1). The porous microstructure makes the FTEP ultra-sensitive to external pressure, and the reinforcements endow the device with a greater deformation limit in a wide detection range. Finally, a novel concept of the wearable Internet of Healthcare(Io H) system for real-time physiological signal monitoring has been proposed, which could provide real-time physiological information for ambulatory personalized healthcare monitoring.Hao Lei Haifeng Ji Xiaohan Liu Bohan Lu Linjie Xie Eng Gee Lim Xin Tu Yina Liu Peixuan Zhang Chun Zhao Xuhui Sun Zhen Wen 2023Nano-Micro Letters2023,15,7:0
15In-situ composite microstructure formation of immiscible alloy solidified in space显示文摘About one-third of alloys show a phase diagram with a miscibility gap in the liquid state.The solidifications of these alloys proceed with a liquid-liquid decomposition and have great potential in the development of high-performance in-situ particulate composites,and composites with a core/shell structure.Jiuzhou Zhao Hao Sun Lili Zhang Hongxiang Jiang Linjie Yang Jie He 2023National Science Review2023,10,2:0
16Potential damage threats to downstream optics caused by Gaussian mitigation pits on rear KDP surface显示文摘To determine whether a potassium dihydrogen phosphate(KDP)surface mitigated by micro-milling would potentially threaten downstream optics,we calculated the light-field modulation based on angular spectrum diffraction theory,and performed a laser damage test on downstream fused silica.The results showed that the downstream light intensification caused by a Gaussian mitigation pit of 800μm width and 10μm depth reached a peak value near the KDP rear surface,decreased sharply afterward,and eventually kept stable with the increase in downstream distance.The solved peak value of light intensification exceeded 6 in a range 8–19 mm downstream from the KDP rear surface,which is the most dangerous for downstream optics.Laser damage sites were then induced on the fused silica surface in subsequent laser damage tests.When the distance downstream was greater than 44 mm with a downstream light intensification of less than 3,there were no potential damage threats to downstream optics.The study proves that a mitigated KDP surface can cause laser damage to downstream optical components,to which attention should be paid in an actual application.Through this work,we find that the current manufacturing process and the mitigation index still need to be improved.The research methods and calculation models are also of great reference significance for related studies like optics mitigation and laser damage.Hao Yang Jian Cheng Zhichao Liu Qi Liu Linjie Zhao Chao Tan Jian Wang Mingjun Chen 2020High Power Laser Science and Engineering2020,8,4:0
17Global Profiling of 2-hydroxyisobutyrylome in Common Wheat显示文摘As a novel post-translational modification(PTM),lysine 2-hydroxyisobutyrylation(Khib)is considered to regulate gene transcriptional activities in eukaryotic cells;however,the functions of Khib-modified proteins in plants remain unknown.Here,we report that Khib is an evolutionarilyconserved PTM in wheat and its progenitors.A total of 3348 Khib sites on 1074 proteins are identified in common wheat(Triticum aestivum L.)by using affinity purification and mass spectroscopy of 2-hydroxyisobutyrylome.Bioinformatic data indicate that Khib-modified proteins participate in a wide variety of biological and metabolic pathways.Immunoprecipitation confirms that Khibmodified proteins are present endogenously.A comparison of Khib and other main PTMs shows that Khib-modified proteins are simultaneously modified by multiple PTMs.Using mutagenesis experiments and co-immunoprecipitation assays,we demonstrate that Khib on K206 of phosphoglycerate kinase(PGK)is a key regulatory modification for its enzymatic activity,and mutation on K206 affects the interactions of PGK with its substrates.Furthermore,Khib modification of low-molecular-weight proteins is a response to the deacetylase inhibitors nicotinamide and trichostatin.This study provides evidence to promote our current understanding of Khib in wheat plants,including the cooperation between Khib and its metabolic regulation.Ning Zhang Lingran Zhang Linjie Li Junyou Geng Lei Zhao Yan Ren Zhongdong Dong Feng Chen 2022Genomics, Proteomics & Bioinformatics2022,20,4:0
18农用发电机整流子损坏的修复显示文摘老式带专用直流励磁机的发电机,整流子容易损坏,介绍一种既简便易行、又经济可靠的修复方法,对边远山区、农场小型水电站具有一定的实用价值.Zhao Linji(Nanfen County Hydroelectric Bureau Nanfen 344500) 1994江西水利科技1994,20,2:0
19The Vlasov-Poisson-Boltzmann system for non-cutof hard potentials显示文摘This paper is concerned with the construction of globally smooth solutions near a given global Maxwellian to the Cauchy problem of the Vlasov-Poisson-Boltzmann system for non-cutof hard potentials in three space dimensions without the neutral condition imposed on the initial perturbation.Our analysis is based on the time-weighted energy method and some delicate estimates.XIAO QingHua XIONG LinJie ZHAO HuiJiang 2014Science China Mathematics2014,57,3:0
20Cross-species recognition and molecular basis of SARS-CoV-2 and SARS-CoV binding to ACE2s of marine animals显示文摘Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has an extremely broad host range that includes hippopotami,which are phylogenetically closely related to whales.The cellular ACE2 receptor is one of the key determinants of the host range.Here,we found that from several marine mammals and hippopotami could efficiently bind to the receptor-binding domain(RBD)of both SARS-C oV and SARS-C oV-2 and facilitate the trans duction of SARS-C oV and SARS-C oV-2 pseudo viruses into ACE2-expressing cells.We further resolved the cryo-electron microscopy complex structures of the minke whale ACE2 and sea lion ACE2,respectively,bound to the RBDs,revealing that they have similar binding modes to human ACE2 when it comes to the SARS-C oV-2 RBD and SARS-C oV RBD.Our results indicate that marine mammals could potentially be new victims or virus carriers of SARS-C oV-2,which deserves further careful investigation and study.It will provide an early warning for the prospective monitoring of marine mammals.Shihua Li Ruirui Yang Di Zhang Pu Han Zepeng Xu Qian Chen Runchu Zhao Xin Zhao Xiao Qu Anqi Zheng Liang Wang Linjie Li Yu Hu Rong Zhang Chao Su Sheng Niu Yanfang Zhang Jianxun Qi Kefang Liu Qihui Wang George F.Gao 2022National Science Review2022,9,9:0
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