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| 1 | Using borehole core analysis to reveal Late Quaternary paleoearthquakes along the Nankou-Sunhe Fault,Beijing显示文摘The Nankou-Sunhe Fault is a buried active normal fault that traverses the urban area of Beijing.Its seismic risks have caused considerable concerns.This paper studies paleoearthquakes along this fault by analyzing and correlating bore-hole cores obtained from triple-tube coring,incorporating experience acquired from trenching.As a result,a model for identifying earthquake-derived colluvium by sediment-core analysis is proposed.Triple-tube coring technique is useful to collect continuous undis-turbed soil core near the Nankou-Sunhe Fault.By identifying fault-scarp colluviums,determining cumulative displacement,and analysing stratum thickening on the hanging wall,we are able to establish a preliminary paleoearthquake sequence consisting of 13 surface-rupturing events since 60 ka.The seismic history can be divided into three periods based on different recurrence intervals.Between 60 and 40 ka,three earthquakes occurred with recurrence interval of ~10 ka.From 40 to 25 ka,there were six earthquakes with the recurrence interval of about 2.5 ka.In the last 25 ka,four earthquakes have taken place with the recurrence interval varying considerably.The recurrence interval between the last three events is ~5 ka.Smaller recurrence intervals correspond to stages of faster fault slip.The coseismic displacement of a single event is 0.8 to 2.2 m,average 1.4 m,largely equivalent to moment magnitudes 6.7-7.1.This study demonstrates the feasibility of bore-hole drilling in investigating paleoearthquakes along normal faults.It also suggests that closely spaced boreholes with continuous undisturbed cores are essential for reconstructing the complete paleoearthquake sequence. | ZHANG ShiMin WANG DanDan LIU XuDong ZHANG GuoHong ZHAO JunXiang LUO MingHui REN JunJie WANG Rui ZHANG YingLi | 2008 | Science China Earth Sciences2008，51，8： | 11 |
| 2 | Counteraction of ABA-Mediated Inhibition of Seed Germination and Seedling Establishment by ABA Signaling Terminator in Arabidopsis显示文摘Seed germination and seedling establishment are important for the reproductive success of plants,but seeds and seedlings typically encounter constantly changing environmental conditions.By inhibiting seed germination and post-germinative growth through the PYR1/PYL/RCAR ABA receptors and PP2C co-receptors,the phytohormone abscisic acid(ABA)prevents premature germination and seedling growth under unfavorable conditions.However,little is known about how the ABA-mediated inhibition of seed germination and seedling establishment is thwarted.Here,we report that ABA Signaling Terminator(ABT),a WD40 protein,efficiently switches off ABA signaling and is critical for seed germination and seedling establishment.ABT is induced by ABA in a PYR1/PYL/RCAR-PP2C-dependent manner.Overexpression of ABT promotes seed germination and seedling greening in the presence of ABA,whereas knockout of ABT has the opposite effect.We found that ABT interacts with the PYR1/PYL/RCAR and PP2C proteins,interferes with the interaction between PYR1/PYL4 and ABI1/ABI2,and hampers the inhibition of ABI1/ABI2 by ABA-bound PYR1/PYL4,thereby terminating ABA signaling.Taken together,our results reveal a core mechanism of ABA signaling termination that is critical for seed germination and seedling establishment in Arabidopsis. | Zhijuan Wang Ziyin Ren Chunhong Cheng Tao Wang Hongtao Ji Yang Zhao Zhiping Deng Liya Zhi Jingjing Lu Xinying Wu Shimin Xu Mengmeng Cao Hongtao Zhao Liu Liu Jiankang Zhu Xia Li | 2020 | Molecular Plant2020，13，9： | 10 |
| 3 | Reservoir reconstruction technologies for coalbed methane recovery in deep and multiple seams显示文摘Multiple coal seams widely develop in the deep Chinese coal-bearing strata. Ground in situ stress and coal seam gas pressure increase continuously with the increase of the mining depth, and coal and gas outburst disasters become increasingly severe. When the coal is very deep, the gas content and pressure will elevate and thus coal seams tends to outburst-prone seams. The safety and economics of exploited firstmined coal seams are tremendously restricted. Meanwhile, the multiple seams occurrence conditions resulted in different methane pressure systems in the coal-bearing strata, which made the reservoir reconstruction of coal difficult. Given the characteristics of low saturation, low permeability, strong anisotropy and soft coal of Chinese coal seams, a single hydraulic fracturing surface well for reservoir reconstruction to pre-drain the coalbed methane(CBM) of multiple seams concurrently under the different gas pressure systems has not yet gained any breakthroughs. Based on analyses of the main features of deep CBM reservoirs in China, current gas control methods and the existing challenges in deep and multiple seams, we proposed a new technology for deep CBM reservoir reconstruction to realize simultaneous high-efficiency coal mining and gas extraction. In particular, we determined the first-mined seam according to the principles of effectiveness and economics, and used hydraulic fracturing surface well to reconstruct the first-mined seam which enlarges the selection range of the first-mined seam. During the process of mining first-mined seam, adjacent coal seams could be reconstructed under the mining effect which promoted high-efficiency pressure relief gas extraction by using spatial and comprehensive gas drainage methods(combination of underground and ground CBM extraction methods). A typical integrated reservoir reconstruction technology, ‘‘One well for triple use', was detailed introduced and successfully applied in the Luling coal mine. The application showed that the proposed technology could effectively promote coal mining safety and simultaneously high-efficiency gas extraction. | Wang Liang Liu Shimin Cheng Yuanping Yin Guangzhi Zhang Dongming Guo Pinkun | 2017 | International Journal of Mining Science and Technology2017，27，2： | 10 |
| 4 | The effect of nanohybrid materials on the pour-point and viscosity depressing of waxy crude oil显示文摘The pipeline transportation of waxy crude oil is a problem both at home and abroad.In this paper,a novel nanohybrid pour-point depressant (PPD) was used to decrease the pour point and viscosity of waxy crude oil.The pour point and apparent viscosity of waxy crude oil was decreased significantly upon addition of the nanohybrid PPD,and the long-term stability of the nanohybrid PPD was superior to that of a conventional ethylene-vinyl acetate copolymer PPD.Polarized optical microscopy and X-ray diffraction were used to study the effect of the nanohybrid PPD on the crystallization of crude oil.Addition of the nanohybrid PPD reduced the amount of wax crystals,prevented their aggregation,and reduced the temperature at which the crude oil started to crystallize.The significant effect of this nanohybrid PPD on the pour point and viscosity depressing of crude oil is of great importance for facilitating the safe,efficient and energy-minimized transportation of waxy crude oil. | WANG Feng ZHANG DongMin DING YanFen ZHANG LiXin YANG MingShu JIANG BaoLiang ZHANG ShiMin AI MuYang LIU GuangWen ZHI ShuJie HUO LianFeng OUYANG Xin LI Li | 2011 | Chinese Science Bulletin2011，56，1： | 9 |
| 5 | Organic Geochemical and Petrographic Characteristics of the Coal Measure Source Rocks of Pinghu Formation in the Xihu Sag of the East China Sea Shelf Basin: Implications for Coal Measure Gas Potential显示文摘Coal measure source rocks, located in the Xihu Sag of the East China Sea Shelf Basin, were analyzed to define the hydrocarbon generation potential, organic geochemistry/petrology characteristics, and coal preservation conditions. The Pinghu source rocks in the Xihu Sag are mainly gas-prone accompany with condensate oil generation. The coals and shales of the Pinghu Formation are classified from 'fair' to 'excellent' source rocks with total organic carbon(TOC) contents ranging from 25.2% to 77.2% and 1.29% to 20.9%, respectively. The coals are richer in TOC and S1+S2 than the shales, indicating that the coals have more generation potential per unit mass. Moreover, the kerogen type of the organic matter consists of types Ⅱ-Ⅲ and Ⅲ, which the maturity Ro ranges from 0.59% to 0.83%. Petrographically, the coals and shales are dominated by vitrinite macerals(69.1%–96.8%) with minor proportions of liptinite(2.5%–17.55%) and inertinite(0.2%–6.2%). The correlation between maceral composition and S1+S2 indicates that the main contributor to the generation potential is vitrinite. Therefore, the coals and shales of the Pinghu Formation has good hydrocarbon generation potential, which provided a good foundation for coal measure gas accumulation. Furthermore, coal facies models indicates that the Pinghu coal was deposited in limno-telmatic environment under high water levels, with low tree density(mainly herbaceous) and with low-moderate nutrient supply. Fluctuating water levels and intermittent flooding during the deposition of peat resulted in the inter-layering of coal, shale and sandstone, which potentially providing favorable preservation conditions for coal measure gas. | WANG Yang QIN Yong YANG Liu LIU Shimin Derek ELSWORTH ZHANG Rui | 2020 | Acta Geologica Sinica(English Edition)2020，94，2： | 6 |
| 6 | New Discovery of Molybdenite in the Dongping Gold Deposit, Hebei Province, China and its Re-Os Geochronological Implications显示文摘The Dongping gold deposit is located on the northern margin of the North China Craton,and is the largest alkaline pluton-related gold deposit in China(Bao et al.,2014),which is characterized by its large amounts of tellurides.The deposit is largely hosted in the Shuiquangou syenitic complex and consists of auriferous quartz veins and disseminated sulfide ores.It has been extensively studied since its discovery in the 1980s;however the geochronology and genesis of the deposit are still controversial.Nie(1998)considered that the deposit was formed in the Devonian. | WANG Dazhao LIU Jiajun ZHAI Degao ZHEN Shimin WANG Jiang YANG Xi'an | 2019 | Acta Geologica Sinica(English Edition)2019，93，3： | 5 |
| 7 | Nano CuO/ZSM-5 zeolite as a green and efficient catalyst for dehydration of 1,4-butanediol to tetrahydrofuran显示文摘Nano CuO/ZSM-5 zeolite was prepared and used as a catalyst for dehydration of 1,4-butanediol(BDO) to tetrahydrofuran(THF) in liquid-phase. It was found that the 4.6 wt% CuO/ZSM-5 displayed good catalytic performance, and nearly 100%of BDO conversion and more than 99% of THF selectivity could be achieved by a rotary evaporator reactor at 170 °C under the atmospheric pressure. With such mild reaction conditions, 2400 g BDO could be converted to THF over 1 g catalyst under semi-continuous operation. Characterizations with X-ray diffraction(XRD), temperature-programmed reduction(TPR),NH3-temperature programmed desorption(TPD), X-ray photoelectron spectroscopy(XPS), transmission electron microscope(TEM) and Brunauer-Emmett-Teller(BET) over fresh and used 4.6 wt% CuO/ZSM-5 were conducted. Based on the results of the characterization and catalytic performance of 4.6 wt% CuO/ZSM-5, it can be conjectured that the formed 1–3 nm CuO nanoparticles, suitable acidity of the catalyst due to the synergic interaction of CuO and ZSM-5 support promoted the dehydration of BDO to THF. | Yan Long Shimin Liu Yuqing Fei Qinghe Li Youquan Deng | 2017 | Science China Chemistry2017，60，7： | 3 |
| 8 | Dynamic failure risk of coal pillar formed by irregular shape longwall face:A case study显示文摘Irregular shape workface would result in the presence of coal pillar, which leads to high stress concentration and possibly induces coal bumps. In order to study the coal bump mechanism of pillars, static and dynamic stress overlapping(SDSO) method was proposed to explain the impacts of static stress concentration and tremors induced by mining activities. The stress and deformation in surrounding rock of mining face were analyzed based on the field case study at 1303 workface in Zhaolou Coal Mine in China.The results illustrate that the surrounding rock of a workface could be divided into four different zones,i.e., residual stress zone, stress decrease zone, stress increase zone and original stress zone. The stress increase zone is prone to failure under the SDSO impact loading conditions and will provide elastic energy for inducing coal bump. Based on the numerical modelling results, the evolution of static stress in coal pillar as the size of gob increasing was studied, and the impact of dynamic stress was investigated through analyzing the characteristics of tremor activities. The numerical results demonstrate the peak value of vertical stress in coal pillar rises from about 30 MPa with mining distance 10 m to 52.6 MPa with mining distance 120 m, and the location of peak stress transfers to the inner zone of coal pillars as the workface moves forward. For the daily tremor activities, tremors with high energy released indicate high dynamic stress disturbance on the surrounding rock, therefore, the impact of dynamic stressing is more serious during workface extension period because the tremor frequency and average energy after workface extension are higher than those before the workface extension. | Yixin Zhao Hao Wang Shimin Liu Zonglong Mu Zhiguo Lu | 2018 | International Journal of Mining Science and Technology2018，28，5： | 3 |
| 9 | Burden of pancreatitis and associated risk factors in China,1990 to 2019:a systematic analysis for the Global Burden of Disease Study 2019显示文摘Background: Pancreatitis is a common disease of the digestive system. Acute pancreatitis is one of the most common reasons for gastrointestinal hospital admission, and chronic pancreatitis significantly reduces quality of life. However, national epidemiological data on pancreatitis in China are lacking. This study aimed to quantify the disease burden of pancreatitis in China from 1990 to 2019.Methods: This study was based on the Global Burden of Disease Study 2019 dataset. Age-standardized rates of incidence (ASIR), prevalence (ASPR), mortality (ASMR), and disability-adjusted life years (DALYs) were used to describe the disease burden of pancreatitis, and estimated annual percentage change (EAPC) was used to indicate the average change in age-standardized rates. We also described the trend of pancreatitis-related mortality and DALYs, which are attributable to alcohol use by age and sex.Results: From 1990 to 2019, the ASIR, ASPR, ASMR, and age-standardized DALYs of pancreatitis in China decreased by 10.90, 1.50, 0.49, and 15.54 per 100,000, respectively, with EAPCs of -1.35 (95% uncertainty interval [UI]: -1.67, -1.02) and -0.37 (95% UI: -0.43, -0.31), -2.01 (95% UI: -2.07, -1.94) and -2.32 (95% UI: -2.37, -2.28), respectively. Recently, the numbers of incident and prevalent cases have risen, with estimates of 380,018 (95% UI: 308,669-462,767) and 493,765 (95% UI: 416,705-578,675), respectively, in 2019. Among men, the disease burden of pancreatitis was more severe than among women, and with variances in the distribution among different age groups. Age-standardized DALYs caused by alcohol-related pancreatitis have gradually worsened in the past decade, accounting for 34.09% of the total in 2019.Conclusions: The disease burden of pancreatitis in China has declined in the past 30 years, but the exacerbation of population aging poses a challenge to prevention and control of pancreatitis. Alcohol use has gradually become an important factor in the disease burden of pancreatitis in recent years. | Ke Han Shimin Chen Yang Song Chen Du Fei Gao Shaohua Liu Yao He Ningli Chai Enqiang Linghu Miao Liu | 2022 | Chinese Medical Journal2022，，11： | 3 |
| 10 | Effect of Doped Boron on the Properties of ZnO Thin Films Prepared by Sol-gel Spin Coating显示文摘 | WEN Bin LIU Chaoqian FEI Weidong WANG Hualin LIU Shimin WANG Nan CHAI Weiping | 2014 | Chemical Research in Chinese Universities2014，30，3： | 3 |
| 11 | RNA interference-mediated silencing of vATPase subunits A and E affect survival and development of the 28-spotted ladybeetle,Henosepilachna vigintioctopunctata显示文摘RNA interference(RNAi)has emerged as a powerful tool for developing novel management strategies for controlling insect pests.The 28-spotted ladybeetle,Henosepilachna vigintioctopunctata is one of the most important pests attacking solanaceous plants in Asia.In this study,the potential of dietary RNAi to manage H.vigintioctopunctata was investigated using both in vitro synthesized and bacterially expressed double-stranded RNAs(dsRNAs)of HvvATPase A and HvvATPase E.The expression levels of HvvATPase A and HvvATPase E were higher in Malpighian tubules than in other tissue types.The silencing of HvvATPase A and HvvATPase E led to significant mortality in H.vigintioctopunctata larvae.In addition,the ingestion of HvvATPase A and HvvATPase E significantly deterred feeding behavior and subsequently arrested the development of H.vigintioctopunctata.Notably,the bacterially expressed dsRNAs consistently caused higher mortality in larvae and adults.Finally,the nontarget effects of the dsRNAs of H.vigintioctopunctata on the predatory ladybeetle Propylaea japonica were evaluated.P.japonica 1st instar larvae were administered vATPase A and vATPase E dsRNAs from H.vigintioctopunctata and P.japonica under the worst-case scenario,in which dsGFP served as negative control.There were significant effects of dsHvvATPase A on P.japonica at the transcriptional level but not at the organismal level,whereas dsHvvATPase E did not effect P.japonica at either the transcriptional or the organismal level.Collectively,the results of the study suggest that HvvATPase A and HvvATPase E can act as novel molecular targets for the control of H.vigintioctopunctata. | Wei Guo Mujuan Guo Chunxiao Yang Zhuoqi Liu Shimin Chen Jing Lu Baoli Qiu Youjun Zhang Xuguo Zhou Huipeng Pan | 2021 | Insect Science2021，28，6： | 3 |
| 12 | Identification of New Resistance Loci Against Sheath Blight Disease in Rice Through Genome-Wide Association Study显示文摘Sheath blight(SB) caused by the soil borne pathogen Rhizoctonia solani is one of the most serious global rice diseases. Breeding resistant cultivar is the most economical and effective strategy to control the disease. However, no rice varieties are completely resistant to SB, and only a few reliable quantitative trait loci(QTLs) linked with SB resistance have been identified to date. In this study, we conducted a genome-wide association study(GWAS) of SB resistance using 299 varieties from the rice diversity panel 1(RDP1) that were genotyped using 44 000 high-density single nucleotide polymorphism(SNP) markers. Through artificial inoculation, we found that only 36.5% of the tested varieties displayed resistance or moderate resistance to SB. In particular, the aromatic and aus sub-populations displayed higher SB resistance than the tropical japonica(TRJ), indica and temperate japonica sub-populations. Seven varieties showed similar resistance levels to the resistant control YSBR1. GWAS identified at least 11 SNP loci significantly associated with SB resistance in the three independent trials, leading to the identification of two reliable QTLs, qSB-3 and qSB-6, on chromosomes 3 and 6. Using favorable alleles or haplotypes of significantly associated SNP loci, we estimated that both QTLs had obvious effects on reducing SB disease severity and can be used for enhancing SB resistance, especially in improving SB resistance of TRJ sub-population rice varieties. These results provided important information and genetic materials for developing SB resistant varieties through breeding. | CHEN Zongxiang FENG Zhiming KANG Houxiang ZHAO Jianhua CHEN Tianxiao LI Qianqian GONG Hongbing ZHANG Yafang CHEN Xijun PAN Xuebiao LIU Wende WANG Guoliang ZUO Shimin | 2019 | Rice science2019，26，1： | 3 |
| 13 | Current status,trends,and predictions in the burden of gallbladder and biliary tract cancer in China from 1990 to 2019显示文摘Background:Gallbladder and biliary tract cancer(GBTC)has greatly damaged the health of patients and is accompanied by a dismal prognosis.The worldwide distribution of GBTC shows extensive variance and the updated data in China is lacking.This study was to determine the current status,trends,and predictions in the burden of GBTC over the past 30 years in China.Methods:This was a descriptive,epidemiological,secondary analysis of the Global Burden of Disease,Injuries,and Risk Factor Study 2019 data.Data including incidence,prevalence,mortality,and disability-adjusted life years(DALYs)of GBTC in China by year,age,and sex were assessed.Joinpoint regression analysis was conducted to evaluate trends of disease burden due to GBTC from 1990 to 2019.Nordpred age-period-cohort analysis was applied for the projection of mortality and incidence due to GBTC from 2019 to 2044.Results:Nationally,there were 38,634(95%uncertainty interval[UI]:27,350-46,512)new cases and 47,278(95%UI:32,889-57,229)patients due to GBTC,causing 34,462(95%UI:25,220-41,231)deaths,and 763,584(95%UI:566,755-920,493)DALYs in 2019.Both cases and rates of burden owing to GBTC were heavier among males and at old age.From 1990 to 2019,the age-standardized rates of incidence,prevalence,mortality,and DALYs of GBTC generally increased from 1990 to 2019,with average annual percentage change at 0.8%(95%confidential interval[CI]:0.6-1.0%),1.3%(95%CI:1.1-1.5%),0.4%(95%CI:0.2-0.6%),and 0.2%(95%CI:0.1-0.4%),respectively.Even though the age-standardized incidence rate and agestandardized mortality rate in both sexes were predicted to decline gradually from 2019 to 2044,the number of new cases and deaths were expected to grow steadily.Conclusions:GBTC is becoming a major health burden in China,particularly among males and older individuals.Given the aging population and increasing burden,effective strategies and measurements are urged to prevent or reduce the number of new cases and deaths of GBTC. | Shimin Chen Ke Han Yang Song Shaohua Liu Xuehang Li Shengshu Wang Haowei Li Rongrong Li Jianhua Wang Yao He Miao Liu | 2022 | Chinese Medical Journal2022，，14： | 2 |
| 14 | Water sorption on coal:effects of oxygen-containing function groups and pore structure显示文摘Coal-water interactions have profound influences on gas extraction from coal and coal utilization.Experimental measurements on three coals using X-ray photoelectron spectroscopy(XPS),low-temperature nitrogen adsorption and dynamic water vapor sorption(DVS)were conducted.A mechanism-based isotherm model was proposed to estimate the water vapor uptake at various relative humidities,which is well validated with the DVS data.The validated isotherm model of sorption was further used to derive the isosteric heat of water vapor sorption.The specific surface area of coal pores is not the determining parameter that controls water vapor sorption at least during the primary adsorption stage.Oxidation degree dominates the primary adsorption,and which togethering with the cumulative pore volume determine the secondary adsorption.Higher temperature has limited effects on primary adsorption process.The isosteric heat of water adsorption decreases as water vapor uptake increases,which is found to be close to the latent heat of bulk water condensation at higher relative humidity.The results confirmed that the primary adsorption is controlled by the stronger bonding energy while the interaction energy between water molecules during secondary adsorption stage is relatively weak.However,the thermodynamics of coal-water interactions are complicated since the internal bonding interactions within the coal are disrupted at the same time as new bonding interactions take place within water molecules.Coal has a shrinkage/swelling colloidal structure with moisture loss/gain and it may exhibit collapse behavior with some collapses irreversible as a function of relative humidity,which further plays a significant role in determining moisture retention. | Ang Liu Shimin Liu Peng Liu Kai Wang | 2021 | International Journal of Coal Science & Technology2021，8，5： | 2 |
| 15 | Gas diffusion behavior of coal and its impact on production from coalbed methane reservoirs显示文摘 | Mallikarjun Pillalamarry Satya Harpalani Shimin Liu | 2011 | International Journal of Coal Geology2011，，4： | 2 |
| 16 | China-Indian Silk Trade:Current Production and Future Prospects显示文摘As an important traditional labor-intensive industry of both India and China, the cocoon silk industry has long made great contributions to the ecological environment protection, rural economic development and the increase in export income of both countries. India is not only a very important cocoon silk trading partner, but an important production competitor of China. In recent years, there has been a large increase in the production and trade of the cocoon silk between China and India; however, China relies heavily on Indian market, which leads to a tendency of further deterioration in the silk trade environment between both countries. The present article makes an empirical study of the cocoon silk resources of the two countries and the scale, product mix and market structure of China-Indian silk trade from 2001 to 2007. Overall silk trading volumes from China to India and market concentration rate are on the increase because of the superiority of Chinese cocoon silk production over that of India. Owing to scattered market share and export that mainly focused on raw materials product, there has been a phenomenon of price reduction and quantity increase. India carries out fierce competition with China in the international market and even imposes antidumping sanction on Chinese silk, which are key factors restricting further increase between China-India trade. Based on the abovementioned facts, the authors aim to put forward suggestions for steadily developing the production and trade of China's silk. | Liu Feng Sun Shimin Qiao Xianjuan | 2009 | Chinese Journal of Population,Resources and Environment2009，7，2： | 2 |
| 17 | A switch-on molecular biosensor for detection of caspase-3 and imaging of apoptosis of cells显示文摘Apoptosis is a form of programmed cell death that is essential for maintaining internal environmental stability.Disordered apoptosis can cause a variety of diseases;therefore,sensing apoptosis can provide help in study of mechanism of the relevant diseases and drug development.It is known that caspase-3 is a key enzyme involved in apoptosis and the expression of its activity is an indication of apoptosis.Here,we present a genetically encoded switch-on m Neon Green2-based molecular biosensor.m Neon Green2 is the brightest monomeric green fluorescent protein.The substrate of caspase-3,DEVD amino acid residues,is inserted in it,while cyclized by insertion of Nostoc punctiforme Dna E intein to abolish the fluorescence(inactive state).Caspase-3-catalyzed cleavage of DEVD linearizes m Neon Green2 and rebuilds the natural barrel structure to restore the fluorescence(activated state).The characterization exhibited that the Caspase-3 biosensor has shortened response time,higher sensitivity,and prolonged functional shelf life in detection of caspase-3 amongst the existing counterparts.We also used the Caspase-3 biosensor to evaluate the effect of several drugs on the induction of apoptosis of He La and MCF-7 tumor cells and inhibition of Zika virus invasion. | Rui Gong Dianbing Wang Ghulam Abbas Shimin Li Qian Liu Mengmeng Cui Xian-En Zhang | 2022 | Science China(Life Sciences)2022，65，3： | 2 |
| 18 | Active and stable Cu doped NiMgAlO catalysts for upgrading ethanol to n-butanol显示文摘Upgrading ethanol to n-butanol is an attractive way for renewable n-butanol production. Herein, Cu was selected to modify NiMgAlO catalysts for improving ethanol conversion and n-butanol selectivity. Over the optimized 2%Cu-NiMgAlO catalyst, ethanol conversion and n-butanol selectivity were enhanced to 30.0% and 64.2%, respectively, in 200 h time on stream at 523 K. According to physicochemical characterizations and theoretical calculations, the key role of multiple active sites in this reaction was extensively investigated. The plate-like structure of hydrotalcite was maintained over 2%Cu-NiMgAlO catalysts, with an average Ni particle size of ca. 5.4 nm. The presence of Cu species created CuNi alloy sites and Lewis acid-base pairs, and increased hydrogen transfer and condensation reactions, resulting in elevated ethanol conversion and n-butanol selectivity. Additionally, CuNi alloy had a strong interaction with CuNiMgAl oxides, forming homogeneous boundary due to their close ionic radius and lattice matching, and afforded the long time stability in the ethanol to n-butanol reaction. | Zhinuo Wang Ming Yin Jifeng Pang Xianquan Li Yanan Xing Yang Su Shimin Liu Xiaoyan Liu Pengfei Wu Mingyuan Zheng Tao Zhang | 2022 | Journal of Energy Chemistry2022，31，9： | 2 |
| 19 | Important Green Chemistry and Catalysis: Non-phosgene Syntheses of Isocyanates - Thermal Cracking Way显示文摘 | Peixue Wang Shimin Liu Youquan Deng | 2017 | Chinese Journal of Chemistry2017，35，6： | 2 |
| 20 | Effects of processing history and annealing on polymorphic structure of nylon-6/montmorillonite nanocomposites显示文摘 | Shaobo Xie Shimin Zhang Huiju Liu | 2005 | Polymer2005，46，14： | 1 |
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