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| 1 | The HEPD particle detector of the CSES satellite mission for investigating seismo-associated perturbations of the Van Allen belts显示文摘CSES(China Seismo-Electromagnetic Satellite) is a mission developed by CNSA(Chinese National Space Administration) and ASI(Italian Space Agency), to investigate the near-Earth electromagnetic, plasma and particle environment, for studying the seismo-associated disturbances in the ionosphere-magnetosphere transition zone. The anthropogenic and electromagnetic noise,as well as the natural non-seismic electromagnetic emissions is mainly due to tropospheric activity. In particular, the mission aims to confirming the existence of possible temporal correlations between the occurrence of earthquakes for medium and strong magnitude and the observation in space of electromagnetic perturbations, plasma variations and precipitation of bursts with highenergy charged particles from the inner Van Allen belt. In this framework, the high energy particle detector(HEPD) of the CSES mission has been developed by the Italian LIMADOU Collaboration. HEPD is an advanced detector based on a tower of scintillators and a silicon tracker that provides good energy and angular resolution and a wide angular acceptance, for electrons of 3–100 Me V, protons of 30–200 Me V and light nuclei up to the oxygen. CSES satellite has been launched on February 2^(nd), 2018 from the Jiuquan Satellite Launch Center(China). | AMBROSI Giovanni BARTOCCI Simona BASARA Laurent BATTISTON Roberto BURGER William J. CARFORA Luca CASTELLINI Guido CIPOLLONE Piero CONTI Livio CONTIN Andrea DE DONATO Cinzia DE SANTIS Cristian FOLLEGA Francesco M. GUANDALINI Cristina IONICA Maria IUPPA Roberto LAURENTI Giuliano LAZZIZZERA Ignazio LOLLI Mauro MANEA Christian MARCELLI Laura MASCIANTONIO Giuseppe MERGE Matteo OSTERIA Giuseppe PACINI Lorenzo PALMA Francesco PALMONARI Federico PANICO Beatrice PATRIZII Laura PERFETTO Francesco PICOZZA Piergiorgio POZZATO Michele PUEL Matteo RASHEVSKAYA Irina RICCI Ester RICCI Marco RICCIARINI Sergio Bruno SCOTTI Valentina SOTGIU Alessando SPARVOLI Roberta SPATARO Bruno VITALE Vincenzo | 2018 | Science China(Technological Sciences)2018，61，5： | 6 |
| 2 | Type I interferon-mediated pathway interacts with peroxisome proliferator activated receptor-γ (PPAR-γ): At the cross-road of pancreatic cancer cell proliferation显示文摘 | Alessandra Dicitore Michele Caraglia Germano Gaudenzi Gloria Manfredi Bruno Amato Daniela Mari Luca Persani Claudio Arra Giovanni Vitale | 2014 | BBA - Reviews on Cancer2014，，1： | 3 |
| 3 | Obstruction of Mechanical Mitral Prostheses: Analysis of Pathologic Findings显示文摘 | Nicola Vitale Attilio Renzulli Lucio Agozzino Alessio Pollice Nicola Tedesco Luigi de Luca Tupputi Schinosa Maurizio Cotrufo | 1997 | The Annals of Thoracic Surgery1997，，4： | 2 |
| 4 | Diagnosis and classification of relapsing polychondritis显示文摘 | Luca Cantarini Antonio Vitale Maria Giuseppina Brizi Francesco Caso Bruno Frediani Leonardo Punzi Mauro Galeazzi Donato Rigante | 2014 | Journal of Autoimmunity2014，，： | 1 |
| 5 | Application of machine learning techniques to simulate the evaporative fraction and its relationship with environmental variables in corn crops显示文摘Background:The evaporative fraction(EF)represents an important biophysical parameter reflecting the distribution of surface available energy.In this study,we investigated the daily and seasonal patterns of EF in a multi-year corn cultivation located in southern Italy and evaluated the performance of five machine learning(ML)classes of algorithms:the linear regression(LR),regression tree(RT),support vector machine(SVM),ensembles of tree(ETs)and Gaussian process regression(GPR)to predict the EF at daily time step.The adopted methodology consisted of three main steps that include:(i)selection of the EF predictors;(ii)comparison of the different classes of ML;(iii)application,cross-validation of the selected ML algorithms and comparison with the observed data.Results:Our results indicate that SVM and GPR were the best classes of ML at predicting the EF,with a total of four different algorithms:cubic SVM,medium Gaussian SVM,the Matern 5/2 GPR,and the rational quadratic GPR.The com-parison between observed and predicted EF in all four algorithms,during the training phase,were within the 95%confidence interval:the R^(2)value between observed and predicted EF was 0.76(RMSE 0.05)for the medium Gaussian SVM,0.99(RMSE 0.01)for the rational quadratic GPR,0.94(RMSE 0.02)for the Matern 5/2 GPR,and 0.83(RMSE 0.05)for the cubic SVM algorithms.Similar results were obtained during the testing phase.The results of the cross-validation analysis indicate that the R^(2)values obtained between all iterations for each of the four adopted ML algorithms were basically constant,confirming the ability of ML as a tool to predict EF.Conclusion:ML algorithms represent a valid alternative able to predict the EF especially when remote sensing data are not available,or the sky conditions are not suitable.The application to different geographical areas,or crops,requires further development of the model based on different data sources of soils,climate,and cropping systems. | Terenzio Zenone Luca Vitale Daniela Famulari Vincenzo Magliulo | 2022 | Ecological Processes2022，11，1： | 1 |
| 6 | Dose-dependent fetal complications of warfarin in pregnant women with mechanical heart valves显示文摘 | Nicola Vitale Marisa De Feo Luca Salvatore De Santo Alessio Pollice Nicola Tedesco Maurizio Cotrufo | 1999 | Journal of the American College of Cardiology1999，，6： | 1 |
| 7 | Long Term Follow-up and Outcome of Liver Transplantation for Alcoholic Liver Disease: A Single Center Case-control Study显示文摘 | Maurizio Biselli Annagiulia Gramenzi Massimo Del Gaudio Matteo Ravaioli Giovanni Vitale Stefano Gitto Gian Luca Grazi Antonio Daniele Pinna Pietro Andreone Mauro Bernardi | 2010 | Journal of Clinical Gastroenterology2010，，1： | 1 |
| 8 | Microfabricated intracortical extracellular matrix-microelectrodes for improving neural interfaces显示文摘Intracortical neural microelectrodes,which can directly interface with local neural microcircuits with high spatial and temporal resolution,are critical for neuroscience research,emerging clinical applications,and brain computer interfaces(BCI).However,clinical applications of these devices remain limited mostly by their inability to mitigate inflammatory reactions and support dense neuronal survival at their interfaces.Herein we report the development of microelectrodes primarily composed of extracellular matrix(ECM)proteins,which act as a bio-compatible and an electrochemical interface between the microelectrodes and physiological solution.These ECM-microelectrodes are batch fabricated using a novel combination of micro-transfer-molding and excimer laser micromachining to exhibit final dimensions comparable to those of commercial silicon-based microelectrodes.These are further integrated with a removable insertion stent which aids in intracortical implantation.Results from electrochemical models and in vivo recordings from the rat’s cortex indicate that ECM encapsulations have no significant effect on the electrochemical impedance characteristics of ECM-microelectrodes at neurologically relevant frequencies.ECM-microelectrodes are found to support a dense layer of neuronal somata and neurites on the electrode surface with high neuronal viability and exhibited markedly diminished neuroinflammation and glial scarring in early chronic experiments in rats. | Wen Shen Suradip Das Flavia Vitale Andrew Richardson Akshay Ananthakrishnan Laura A.Struzyna Daniel P.Brown Naixin Song Murari Ramkumar Timothy Lucas DKacy Cullen Brian Litt Mark G.Allen | 2018 | Microsystems & Nanoengineering2018，4，1： | 1 |
| 9 | Differential expression of alternatively spliced mRNA forms of the insulin-likegrowth factor 1 receptor in human neuroendocrine tumors显示文摘 | Lorenza Vitale Luca Lenzi Shane Huntsman Silvia Canaider Flavia Frabetti Raffaella Casadei Federica Facchin Paolo Carinci Maria Zannotti Domenico Coppola Pierluigi Strippoli | 2006 | Oncology Reports2006，，： | 1 |
| 10 | Effect of partial fatty acid oxidation inhibition with trimetazidine on mortality and morbidity in heart failure: Results from an international multicentre retrospective cohort study显示文摘 | Gabriele Fragasso Giuseppe Rosano Sang Hong Baek Hamayak Sisakian Pericle Di Napoli Luca Alberti Giliola Calori Seok-Min Kang Laura Sahakyan Armen Sanosyan Cristiana Vitale Giuseppe Marazzi Alberto Margonato Romualdo Belardinelli | 2012 | International Journal of Cardiology2012，，： | 1 |
| 11 | Obstruction of mechanical mitral prosthesis: analysis of pathologic findings显示文摘 | Vitale N Renzulli A Agozzino L Pollice A Tedesco N de Luca Tupputi Schinosa L | 1997 | Ann Thorac Surg1997，63，： | 1 |
| 12 | Remodeling of the cell wall as a drought-tolerance mechanism of a soybean genotype revealed by global gene expression analysis显示文摘Drought stress is major abiotic stress that affects soybean production.Therefore,it is widely desirable that soybean becomes more tolerant to stress.To provide insights into regulatory mechanisms of the stress response,we compared the global gene expression profiles from leaves of two soybean genotypes that display different responses to water-deficit(BR 16 and Embrapa 48,drought-sensitive and droughttolerant,respectively).After the RNA-seq analysis,a total of 5335 down-regulated and 3170 up-regulated genes were identified in the BR16.On the other hand,the number of genes differentially expressed was markedly lower in the Embrapa 48,355 up-regulated and 471 down-regulated genes.However,induction and expression of protein kinases and transcription factors indicated signaling cascades involved in the drought tolerance.Overall,the results suggest that the metabolism of pectin is differently modulated in response to drought stress and may play a role in the soybean defense mechanism against drought.This occurs via an increase of the cell wall plasticity and crosslink,which contributed to a higher hydraulic conductance(Kf)and relative water content(RWC%).The drought-tolerance mechanism of the Embrapa 48 genotype involves remodeling of the cell wall and increase of the hydraulic conductance to the maintenance of cell turgor and metabolic processes,resulting in the highest leaf RWC,photosynthetic rate(A),transpiration(E)and carboxylation(A/Ci).Thus,we concluded that the cell wall adjustment under drought is important for a more efficient water use which promoted a more active photosynthetic metabolism,maintaining higher plant growth under drought stress. | Flaviane Silva Coutinho Juliano Mendonça Rodrigues Lucas Leal Lima Rosilene Oliveira Mesquita Paola Avelar Carpinetti João Paulo Batista Machado Camilo Elber Vital Pedro Marcus Vidigal Maria Eduarda Soares Ramos Mariana Rocha Maximiano Angela Mehta Maria Goreti Almeida Oliveira Elizabeth Pacheco Batista Fontes Humberto Josuéde Oliveira Ramos | 2021 | aBIOTECH2021，2，1： | 0 |
| 13 | Two elective invasive procedures after a single avatrombopag treatment in a patient with liver cirrhosis and severe thrombocytopenia显示文摘Introduction Severe thrombocytopenia(platelet count<50×10^(9)/L)occurs in 1%–2%of patients with liver cirrhosis and is associated with an increased risk of bleeding[1].In this clinical setting,there is no definite agreement on the platelet cut-off below which bleeding risk increases.However,in vitro evidence indicates that thrombin generation is preserved in patients with cirrhosis and platelet counts of>56×10^(9)/L[2].Observational studies found that severe thrombocytopenia may be predictive of post-procedure bleeding after liver biopsy,dental extractions,percutaneous ablation of liver tumors,and endoscopic polypectomy[3]. | Marco Biolato Federica Vitale Giuseppe Marrone Luca Miele Antonio Grieco | 2022 | Gastroenterology Report2022，10，1： | 0 |
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