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| 1 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 2 | Benign and malignant musculoskeletal masses: MR imaging differential enhancement ratios 显示文摘 | Ma LD Frassica FJ McCarthy EF | 1997 | Radiology1997，202，3： | 1 |
| 3 | Glutamate-based depression GBD显示文摘 | Mccarthy DJ Alexander R Smith MA | | Med Hypotheses0，78，5： | 1 |
| 4 | Assessing estimators of snow leopard abundance显示文摘 | MCCARTHY K P FULLER T K MA M | 2008 | The Journal of Wildlife Management2008，72，8： | 1 |
| 5 | Benign and malignant musculoskeletal masses:MR imaging differentiation with rim-to-center differential enhancement ratios显示文摘 | Ma LD Frassica FJ McCarthy EF | 1997 | Radiology1997，202，： | 1 |
| 6 | Reactive compatibilization of biodegradable blends of PLA and PCL 显示文摘 | Wang W Ma Gross R A McCarthy S P | 1998 | Polymer Degradation and Stability1998，59，： | 1 |
| 7 | Benign and malignant musculoskeletal masses: MR imaging differentiation with rim-tocenter differential enhancement ratios 显示文摘 | Ma LD Frassica FJ McCarthy EF | 1997 | Radiololy1997，202，3： | 1 |
| 8 | Carbon dioxide capture-related gas adsorption and separation in metal-organic frameworks显示文摘 | Jian-Rong Li Yuguang Ma M. Colin McCarthy Julian Sculley Jiamei Yu Hae-Kwon Jeong Perla B. Balbuena Hong-Cai Zhou | 2011 | Coordination Chemistry Reviews2011，，15： | 1 |
| 9 | A systematic re-view of reliability and validity studies of methods for measur-ing active and passive cervical range of motion 显示文摘 | Williams MA McCarthy CJ Chorti A | 2010 | J Manipula-tive Physiol Ther2010，33，2： | 1 |
| 10 | Benign and malignant musculoskeletal masses: MR imaging differentiation with rim to center differential enhancement ratios显示文摘 | Ma LD Frassica FJ McCarthy EF | 1997 | Radiology1997，202，： | 1 |
| 11 | Carbon dioxide capture-related gas adsorption and separation metal-organic frameworks 显示文摘 | Li J R Ma Y McCarthy M C | 2011 | Coor- dination Chemistry Reviews2011，255，： | 1 |
| 12 | Benign and malignant musculoskeletal masses: MR imaging differentiation with rim-to-center differential enhancement ratios显示文摘 | Frassica FJ McCarthy EF | 1997 | Radiology1997，202，： | 1 |
| 13 | Assessing Estimators of Snow Leopard Abundance显示文摘 | MCCARTHY K FULLER T MA M | 2008 | The Journal of Wildlife Management2008，72，8： | 1 |
| 14 | Does preoperative atrial fibrillation reduce survival after coronary artery bypass grafting? 显示文摘 | Quader MA McCarthy PM Gillinov AM | 2004 | AnnThorac Surg2004，77，： | 1 |
| 15 | Factors noted to affect breast cancer treatment decisions of women aged 80 and older 显示文摘 | Schonberg MA Silliman RA McCarthy EP | 2012 | J Am Geriatr Sot2012，60，3： | 1 |
| 16 | Winter habitat use of snow leopards in Tomur National Nature Reserve of Xinjiang,Northwest China显示文摘Snow leopards are one of the least known large cats,the population of which has dramatically decreased.Their habitat loss was considered the main reason for the decline during the last decade,but their habitat preferences are still not well known.In this paper,we studied the winter habitat preferences of snow leopards in the Tomur National Nature Reserve(TNNR)in Northwest China during 2004–2005.We used sign surveys and transects to study the winter habitat selection of snow leopards.The results indicated that snow leopards showed a preference for habitat variabilities in slope aspect,vegetation cover,dominant topographical features,landform ruggedness and grazing status.We found that prey availability and dominant topographical features were the most important factors that determined the winter habitat selection of snow leopards.Our results supported the idea that the habitat preferences of snow leopards are a tradeoff between suitable habitat features and avoidance of potential human interactions. | Feng XU Ming MA WeiKang YANG David BLANK YiQun WU Thomas MCCARTHY Bariusha MUNKHTSOG | 2012 | Journal of Arid Land2012，4，2： | 1 |
| 17 | Repeated chair stands as a measure of lower limb strength in sexagenarian women显示文摘 | McCarthy Ek Horvat MA Holtsberg PA | 2004 | Gerontol Med Sci2004，59，： | 1 |
| 18 | Benign and malignant musculoskeletal masses: MR imaging differentiation with rim-to-center differential enhancement ratios 显示文摘 | Ma LD Frassica FJ McCarthy EF | 1997 | Radiology1997，202，3： | 1 |
| 19 | VSL #3<sup>?</sup> probiotic therapy does not reduce portal pressures in patients with decompensated cirrhosis显示文摘 | Saumya Jayakumar Michelle Carbonneau Naomi Hotte A. Dean Befus Chris St. Laurent Richard Owen Mairin McCarthy Karen Madsen Robert J. Bailey Mang Ma Vince Bain Kevin Rioux Puneeta Tandon | 2013 | Liver Int2013，，10： | 1 |
| 20 | Repeated chair stands as a measure of lower limb strength in sexagenarian women显示文摘 | Mccarthy EK Horvat MA Holtsberg PA | 2004 | J Gerontol A Biol Sci Med Sci2004，59，11： | 1 |
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