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| 1 | 铜及其配合物在生物体系中的作用显示文摘自人类有历史记载以来,铜及其配合物即用作药物。铜是人体必需的金属元素。人体的正常代谢过程需要它们,但无法体内合成,因此,需要每天从饮食摄取和吸收。生物药学家和研究者以极大的努力彻底地了解铜及其配合物在生物体系中的作用,希望获得更多地信息以利于人类疾病的预防和治疗。本综述评述了铜在组织中的分配和代谢、铜依赖酶、在病态时铜的非正常代谢、铜配合物的药疗活性和抑制氧自由基的产生。 | Khan* M. Farid Ismail, Norhayati Yusof, Ahmad Pauzi M. Khan*, Gul Majid(School of Pharmaceutical Sciences, University Sains Malaysia, 11800 Pulau Pinang, Malaysia) | 1998 | 无机化学学报1998，14，1： | 7 |
| 2 | Molybdenum sulfide/graphene-carbon nanotube nanocomposite material for electrocatalytic applications in hydrogen evolution reactions显示文摘我们报导铝二硫化物合成的一个三维的层次第三的混血儿(瞬间 2), 减少了 graphene 氧化物(去) ,并且碳 nanotubes (CNT ) 由一个二拍子的圆舞过程准备了。第一,与三维的 microstructuresare 减少了 GOCNT composites 由水的分散的热水的处理综合了去并且经由相互作用形成合成结构的 CNT。然后,瞬间 2 nanoparticles 热水地在 GOCNT 的表面上被种合成。在氢进化反应的这项第三的合成表演上级 electrocatalytic 活动和稳定性与仅仅 35 mV 的一个低发作潜力,~的一个 Tafel 斜坡 38 mVor AuCuFeCo ),并且优化 AuCuFeCo 0.8相应于 134.4 食火鸟的浸透的磁化的 Ni 0.2性能????愠汬祯湩?? | Majid Khan Ammar Bin Yousaf Mingming Chen Chengsha Wei Xibo Wu Ningdong Huang Zemin Qi Liangbin Li | 2016 | Nano Research2016，9，3： | 7 |
| 3 | Systematic study of Ce^(3+) on the structural and magnetic properties of Cu nanosized ferrites for potential applications显示文摘Ce^(3+) substituted Cu-spinel nanoferrites CuCe_xFe_(2-x)O_4(x=0.00, 0.02, 0.04, 0.06, 0.08 and 0.10) were synthesized via sol-gel self-combustion hybrid route. Single phase spinel ferrite of Cu nanoferrites were examined using X-ray diffraction(XRD) analysis whereas the multiphase structure was observed as Ce contents increased from x=0.06. Field emission scanning electron microscopy(FESEM), Thermogravimetric and differential thermal analysis(TGA and DTA) and Fourier transform infrared spectroscopy(FTIR) were used to find out the morphology phase and metal stretching vibrations of Ce^(3+) substituted nanocrystalline ferrites. The crystallite size was increased and found in the range of 25-91 nm. The agglomerations in Cu ferrite samples increase as the Ce^(3+) concentration increases. The magnetic properties such as remanence, saturation magnetization, coercivity, Bohr magneton and magnetocrystalline anisotropy constant(K) were determined using M-H loops recorded from a vibrating sample magnetometer(VSM). Saturation magnetization, remanence and coercivity are increased as the Ce^(3+)contents increase in Cu nanocrystalline samples. Moreover, law of approach to saturation(LoA) was used to calculate the maximum value of saturation for Ce-doped Cu nanoferrites. The soft magnetic behaviour of the Cu nanoferrite is observed as compared to the samples substituted with the increased Ce contents in Cu nanocrystalline ferrite. Bohr magneton and magnetocrystalline anisotropy are found to increase with the substitution of rare earth Ce^(3+) contents in Cu spinel nanocrystalline ferrite. Cedoped Cu nanocrystalline ferrites with excellent properties may be suitable for potential applications in sensing, security, switching, core, multilayer chip inductor, biomedical and microwave absorption applications. | Majid Niaz Akhtar A.B.Sulong M.N.Akhtar Muhammad Azhar Khan | 2018 | Journal of Rare Earths2018，36，2： | 6 |
| 4 | Mechanism and monitoring and early warning technology for rockburst in coal mines显示文摘On the basis of the massive amount of published literature and the long-term practice of our research group in the field of prevention and control of rockburst,the research progress and shortcomings in understanding the rockburst phenomenon have been comprehensively in-vestigated.This study focuses on the occurrence mechanism and monitoring and early warning technology for rockburst in coal mines.Results showed that the prevention and control of rockburst had made significant progress.However,with the increasing mining depth,several unre-solved concerns remain challenging.From the in-depth research and analysis,it can be inferred that rockburst disasters involve three main problems,i.e.,the induction factors are complicated,the mechanism is still unclear,and the accuracy of the monitoring equipment and multi-source stereo monitoring technology is insufficient.The monitoring and warning standards of rockburst need to be further clarified and im-proved.Combined with the Internet of Things,cloud computing,and big data,a study of the trend of rockburst needs to be conducted.Further-more,the mechanism of multiphase and multi-field coupling induced by rockburst on a large scale needs to be explored.A multisystem and multiparameter integrated monitoring and early warning system and remote monitoring cloud platform for rockburst should be explored and developed.High-reliability sensing technology and equipment and perfect monitoring and early warning standards are considered to be the de-velopment direction of rockburst in the future.This research will help experts and technicians adopt effective measures for controlling rock-burst disasters. | Xue-qiu He Chao Zhou Da-zhao Song Zhen-lei Li An-ye Cao Shen-quan He Majid Khan | 2021 | International Journal of Minerals,Metallurgy and Materials2021，28，7： | 3 |
| 5 | Enhancing Dielectric and Mechanical Behaviors of Hybrid Polymer Nanocomposites Based on Polystyrene,Polyaniline and Carbon Nanotubes Coated with Polyaniline显示文摘The dielectric and mechanical properties of hybrid polymer nanocomposites of polystyrene/polyaniline/carbon nanotubes coated with polyaniline(PCNTs) have been investigated using impedance analyzer and extensometer. The blends of PS/PANI formed the heterogeneous phase separated morphology in which PCNTs are dispersed uniformly. The incorporation of a small amount of PCNTs into the blend of PS/PANI has remarkably increased the dielectric properties. Similarly, the AC conductivity of PS/PANI is also increased five orders of magnitude from 1.6 × 10^(-10) to 2.0 × 10^(-5) S·cm^(-1) in the hybrid nanocomposites. Such behavior of hybrid nanocomposites is owing to the interfacial polarization occurring due to the presence of multicomponent domains with varying conductivity character of the phases from insulative PS to poor conductor PANI to highly conductive CNTs. Meanwhile, the tensile modulus and tensile strength are also enhanced significantly up to 55% and 160%, respectively, without much loss of ductility for three phase hybrid nanocomposites as compared to the neat PS. Thereby, the hybrid nanocomposites of PS/PANI/_P CNTs become stiffer, stronger and tougher as compared to the neat systems. | Tanveer ul Haq Zia Ahmad Nawaz Khan Majid Hussain Ibrar Hassan Iftikhar Hussain Gul | 2016 | Chinese Journal of Polymer Science2016，34，12： | 2 |
| 6 | Bioassay-guided isolation of novel and selective urease inhibitors from Diospyros lotus显示文摘Two new dimeric naphthoquinones, 5′,8′-dihydroxy-6,6′-dimethyl-7,3′-binaphthyl-1,4,1′,4′-tetraone(1; Di-naphthodiospyrol D) and 5′,8′-dihydroxy-5,8-dimethoxy-6,6′-dimethyl-7,3′-binaphthyl-1,4,1′,4′-tetraone(2; Di-naphthodiospyrol E), along with known naphthoquinones diospyrin(3) and 8-hydroxy diospyrin(4) were isolated from the chloroform fraction of extract of Diospyros lotus roots. Their structures were elucidated by advanced spectroscopic analyses, including HSQC, HMBC, NOESY, and J-resolved NMR experiments. The fractions and compounds 1-4 were evaluated for urease activity and phosphodiesterase-Ⅰ, carbonic anhydrase-Ⅱ and α-chymotrypsin enzyme inhibitory activities. Compounds 1 and 2 and their corresponding fractions showed significant and selective inhibitory effects on urease activities. The IC_(50) values of 1 and 2 were 260.4 ± 6.37 and 381.4 ± 4.80 μmol·L-1, respectively, using thiourea(IC_(50) = 21 ± 0.11 μmol·L^(-1)) as the standard inhibitor. This was the first report demonstrating that the naphthoquinones class showed urease inhibition. | Abdur Rauf Ghias Uddin Bina S. Siddiqui Ajmal Khan Umar Farooq Farhan A. Khan Syed Majid Bukhari Sher Bahadar Khan | 2017 | Chinese Journal of Natural Medicines2017，15，11： | 2 |
| 7 | 煤岩电磁辐射理论与技术新进展显示文摘煤炭作为我国重要的基础能源和工业原料,其安全开采是保障国家能源安全、支撑经济社会稳定发展的关键。随着浅部煤炭资源的逐渐枯竭,深部开采逐渐成为我国煤炭资源开发新常态,煤岩动力灾害风险随之攀升,严重制约煤炭安全高效开采,对我国煤炭工业可持续发展造成了恶劣的社会负面影响。准确可靠的监测手段是进行煤岩动力灾害防治的必要前提,地球物理监测预警方法通过感知煤岩变形破坏过程中释放的声、电、磁等物理信号来反演煤岩体的损伤破坏状态,已被广泛应用于煤岩动力灾害预警中。其中电磁辐射监测法具有非接触、无损、实时、前兆性强等优势,适用于矿山信息化智能化发展要求。因此,大力推动电磁辐射监测技术的发展,对于煤岩动力灾害防治具有重要意义,可为智慧矿山建设提供重要的技术支持。围绕试验现象、机理模型、技术方法3个方面对电磁辐射理论与技术研究成果进行综述,回顾了电磁辐射现象的发现过程,分析了电磁辐射信号特征、影响因素、力电耦合效应等煤岩电磁辐射特征规律,根据典型电磁辐射机理模型与应力作用、裂纹扩展过程的相关性进行了分类评述,并对现有煤岩电磁辐射监测预警装备及技术方法进行了简要介绍。在此基础上,详细阐述了近年来在煤岩电磁辐射矢量特性研究、煤岩电磁辐射机理微观尺度验证、煤岩电磁辐射定位技术方面取得的新进展。总结了当前煤岩电磁辐射机理未完全揭示和无法实现孕灾区域定位两大理论与技术研究瓶颈,为未来煤岩电磁辐射理论与技术的发展提出了新目标。 | 何学秋 韦梦菡 宋大钊 李振雷 邱黎明 何生全 MAJID Khan 王安虎 | 2023 | 煤炭科学技术2023，51，1： | 2 |
| 8 | Sedative and antinociceptive activities of two new sesquiterpenes isolated from Ricinus communis显示文摘Two new sesquiterpenes, trivially named ricinusoids A(1) and ricinusoids B(2), were isolated from ethyl acetate fraction of Ricinus communis. The structures of new compounds were elucidated by detailed spectroscopic techniques, including 1 D-and 2 D-NMR, UV, IR spectroscopy, and mass spectrometry. The compounds(1-2) were also assessed for in-vivo sedative and analgesic like effects in open field and acetic acid induced writhing tests respectively at 5, 10, and 20 mg·kg^(–1) i.p. Pretreatment of both test compounds caused significant(P ≤ 0.05) reduction in locomotive activity like sedative agents and abdominal constrictions like analgesics. Both compounds(1-2) possessed marked sedative and antinociceptive effects in animal models. | Umar Farooq Ajmal Khan Sadia Naz Abdur Rauf Haroon Khan Afsar Khan Irfan Ullah Syed Majid Bukhari | 2018 | Chinese Journal of Natural Medicines2018，16，3： | 2 |
| 9 | Optimizing coalition formation for tasks with dynamically evolving rewards and nondeterministic action effects显示文摘 | Majid Ali Khan Damla Turgut Ladislau B(o)l(o)ni | | 0，，22： | 1 |
| 10 | Neuro-heuristic computational intelligence for solving nonlinear pantograph systems显示文摘本文提出了一种启发式神经网络计算平台,用于解决基于不同阶数泛函微分方程的非线性受电弓系统(Pantograph systems based on functional differential equations,P-FDEs)中的初值问题(Initial value problems,IVPs)。该方案利用了前馈人工神经网络(Artificial neural networks,ANNs)、基于遗传算法(Genetic algorithms,GAs)的进化计算技术,以及内点技术(Interior-point technique,IPT)。通过设定一个无监督学习误差,针对完全和不完全满足初始条件两种情况,利用ANNs创建了系统的两种数学模型。采用GA–IPT混合算法,对ANN模型的设计参数进行了优化。在GA–IPT中,GA是有效的全局搜索工具,IPT则用于快速的局部收敛。针对三种不同类型的1–3阶P-FDEs的IVPs对该方案进行了测试。通过对比现有的精确解,确认了该方案的正确性。通过采用不同数量神经元的ANN模型进行了大量的数值实验,进一步验证了该方案的准确性和收敛性。 | Muhammad Asif Zahoor RAJA Iftikhar AHMAD Imtiaz KHAN Muhammed Ibrahem SYAM Abdul Majid WAZWAZ | 2017 | Frontiers of Information Technology & Electronic Engineering2017，18，4： | 1 |
| 11 | Studies on drug release kinetics from ibuprofen-carbomer hydrophilic matrix tablets: influence of co-excipients on release rate of the drug 显示文摘 | Majid Khan G Zhu J | 1999 | J Control Release1999，57，： | 1 |
| 12 | A new bioprocess to produce low cost powder formulations of biocontrol bacteria and fungi to control fusarial wilt and root-knot nematode of pulses 显示文摘 | KHAN M R MAJID S MOHIDIN F A | 2011 | Biol Control2011，59，2： | 1 |
| 13 | CE-PLoc: An ensemble classifier for predicting protein subcellular locations by fusing different modes of pseudo amino acid composition 显示文摘 | Khan A Majid A Hayat M | 2011 | Computational Biology and Chemistry2011，35，4： | 1 |
| 14 | The role of graveyards in species conservation and beta diversity:a vegetation appraisal of sacred habitats from Bannu,Pakistan显示文摘Graveyards or sacred groves are often places of natural vegetation protected by spiritual believers because of their sacred beliefs and indigenous culture.A study of graveyards was conducted to determine their role in species conservation,community formation,and associated indicators and species composition using multivariate statistical approaches.It was hypothesized that variations in the age of graveyards would give rise to diverse plant communities under the impact of various edaphic and climatic factors.Quantitative ecological techniques were applied to determine various phytosociological attributes.All the data were put in MS Excel for analysis in PCORD and CANOCO softwares for cluster analysis(CA),two-way cluster analysis(TWCA),indicator species analysis and canonical correspondence analysis.CA and TWCA through Sorenson distance measurements identified five major graveyard plant communities:(1)FicusBougainvillea-Chenopodium;(2)Acacia-Datura-Convolvulus;(3)Ziziphus-Vitex-Abutilon;(4)Acacia-Lantana-Salsola;and(5)Melia-Rhazya-Peganum.Species such as Capparis decidua,Herniaria hirsuta,Salvadora oliedes and Populus euphratica were only present inside graveyards rather than outside and advocate the role of graveyards in species conservation.The impact of different environmental and climatic variables plus the age of the graveyards were also assessed for comparison of plant communities and their respective indicator species.The results indicate that higher chlorine concentration,age of graveyards,low soil electrical conductivity,lower anthropogenic activities,higher nitrogen,calcium and magnesium concentrations in the soil,and sandy soils were the strong environmental variables playing a significant role in the formation of graveyard plant communities,their associated indicators and species distribution patterns.These results could further be utilized to evaluate the role of edaphic and climatic factors,indicator species and conservation management practices at a greater scale. | Saqib Kamran Shujaul Mulk Khan Zeeshan Ahmad Amjad Ur Rahman Majid Iqbal Fazal Manan Zahoor Ul Haq Saif Ullah | 2020 | Journal of Forestry Research2020，31，4： | 1 |
| 15 | Characterization of a cemented sand with the pulse-velocity method显示文摘 | KHAN Z MAJID G CASCANTE G | 2006 | Canadian Geotechnical Journal2006，43，3： | 1 |
| 16 | AFM characterization of surface mechanical and electrical properties of some common rocks显示文摘The characterization of micro-surface mechanical and electrical properties of the natural rock materials remains inadequate,and their macroscopic performance can be better comprehended by investigating the surface properties.With this purpose,the present research focuses on characterizing the microsurface morphology,Derjaguin-Muller-Toporov(DMT)modulus,adhesion,and potential of granite,shale,and limestone by employing the atomic force microscope(AFM)as a pioneer attempt.The results show that the micro-surface morphology of the rock fluctuates within hundreds of nanometers,among which the granite micro-surface is comparatively the smoothest,followed by limestone.The morphology of the shale is the roughest,indicating that the regional difference of shale micro-surface is dominant.The distribution of the adhesion on rock micro-surface is uneven;the average adhesion of eight measuring areas for shale is 23.93 n N,accounting for three times of granite and limestone,while the surface DMT modulus of shale is relatively lower than granite and limestone.It is inferred from the obtained results that higher surface adhesion is helpful to the gas adsorption of shale,and the lower surface DMT(elastic)modulus is useful to the formation of fractures and pores.Thus,these two are the micromechanical basis of shale gas adsorption.Additionally,introducing a method to reduce the surface adhesion will benefit the exploration of unconventional resources such as shale gas.The micro-surface of the three types of rocks all shows electricity,with average potential ranging from tens of millivolts to hundreds of millivolts.Besides,the micro-surface potential of the rocks are heterogeneous,and both positive and negative points can be found.The existence and uneven distribution of micro-surface potential provide a robust physical basis for the electromagnetic radiation generated by rock fracture under loading.This study offers a new method for revealing the adsorption characteristics of unconventional gas reservoir rocks and the electromagnetic radiation mechanism of the rock fracture. | Xianghui Tian Xueqiu He Dazhao Song Zhenlei Li Majid Khan Huifang Liu Liming Qiu | 2022 | International Journal of Mining Science and Technology2022，32，2： | 1 |
| 17 | Floristic composition and ecological gradient analyses of the Liakot Forests in the Kalam region of District Swat,Pakistan显示文摘Kalam Kohistan is a dry,temperate hilly region in the Hindu Raj Series of the Greater Hindu Kush Mountains with diverse forests.As plant distribution and composition is expression of a range of various environmental variables,ecological and floristic attributes of vegetation in the Laikot Forests were therefore evaluated via consecutive explorative trips.These forests have not been evaluated ecologically before due to harsh climatic conditions and issues of accessibility and the study in hand is one of the first in its nature.Quantitative ecological techniques were used to sample forest vegetation and identify species in quadrats of 2 m×2 m for herbs,5 m×5 m for shrubs and 10 m×10 m for trees.All the data of 195 plant species and environmental factors were analyzed via Two-way Cluster Analysis and Canonical Correspondence Analysis using PCORD and CANOCO software.Among 195 plant species from 63 families were 27 species of Asteraceae,the most-speciose family,followed by Poaceae(20 spp.).The dominant life form was therophyte(86 spp.;44%share),followed by phanerophyte(41 spp.;21%share).For the leaf size spectrum,most prevalent was nanophyll(73 spp.;44%)followed by microphyll(66 spp.,34%)and mesophyll(44 spp.;23%).Calcium carbonate,pH,potassium,sand,silt,organic matter,slope aspect and grazing significantly influenced species composition,distribution and habitat.The floristic variation in the region was diverse due to elevational and aspect gradients and thus devided into three zones.This vegetation zonation can be utilized for forest management,species and habitat conservation.Both in situ and ex situ conservation of threatened plant species may improve their conservation status in future if address properly. | Sohail Anwar Shujaul Mulk Khan Zeeshan Ahmad Zahid Ullah Majid Iqbal | 2019 | Journal of Forestry Research2019，30，4： | 1 |
| 18 | An Integrated Deep Learning Framework for Fruits Diseases Classification显示文摘:Agriculture has been an important research area in the field of image processing for the last five years.Diseases affect the quality and quantity of fruits,thereby disrupting the economy of a country.Many computerized techniques have been introduced for detecting and recognizing fruit diseases.However,some issues remain to be addressed,such as irrelevant features and the dimensionality of feature vectors,which increase the computational time of the system.Herein,we propose an integrated deep learning framework for classifying fruit diseases.We consider seven types of fruits,i.e.,apple,cherry,blueberry,grapes,peach,citrus,and strawberry.The proposed method comprises several important steps.Initially,data increase is applied,and then two different types of features are extracted.In the first feature type,texture and color features,i.e.,classical features,are extracted.In the second type,deep learning characteristics are extracted using a pretrained model.The pretrained model is reused through transfer learning.Subsequently,both types of features are merged using the maximum mean value of the serial approach.Next,the resulting fused vector is optimized using a harmonic threshold-based genetic algorithm.Finally,the selected features are classified using multiple classifiers.An evaluation is performed on the PlantVillage dataset,and an accuracy of 99%is achieved.A comparison with recent techniques indicate the superiority of the proposed method. | Abdul Majid Muhammad Attique Khan Majed Alhaisoni Muhammad Asfand Eyar Usman Tariq Nazar Hussain Yunyoung Nam Seifedine Kadry | 2022 | Computers, Materials & Continua2022，，4： | 1 |
| 19 | Preparation, Characterization, and dissolution studies of ibuprofen solid dispersions using polyethylene glycol (PEG), talc, and PEG-talc as dispersion carriers显示文摘 | Gul Majid Khan Zhu JB | 1998 | Drug Dev Ind Pharm1998，24，： | 1 |
| 20 | Characterization and polymorphism of Keratin Associated Protein 1.4 gene in goats显示文摘 | Ruksana Majid Shah Tasleem Ahmad Shamas Ganai Feroz Din Sheikh Syed Shanaz Mir Shabir Hilal Musadikh Khan | 2012 | Gene2012，，： | 1 |
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