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| 1 | Quantitative prediction of the bitterness of atomoxetine hydrochloride and taste-masked using hydroxypropyl-β-cyclodextrin:A biosensor evaluation and interaction study显示文摘The bitterness of a drug is a major challenge for patient acceptability and compliance,especially for children.Due to the toxicity of medication,a human taste panel test has certain limitations.Atomoxetine hydrochloride(HCl),which is used for the treatment of attention deficit/hyperactivity disorder(ADHD),has an extremely bitter taste.The aim of this work is to quantitatively predict the bitterness of atomoxetine HCl by a biosensor system.Based on the mechanism of detection of the electronic tongue(Etongue),the bitterness of atomoxetine HCl was evaluated,and it was found that its bitterness was similar to that of quinine HCl.The bitterness threshold of atomoxetine HCl was 8.61μg/ml based on the Change of membrane Potential caused by Adsorption(CPA)value of the BT0 sensor.In this study,the taste-masking efficiency of 2-hydroxypropyl-β-cyclodextrin(HP-β-CyD)was assessed by Euclidean distances on a principle component analysis(PCA)map with the SA402B Taste Sensing System,and the host–guest interactions were investigated by differential scanning calorimetry(DSC),powder X-ray diffraction(XRD),nuclear magnetic resonance(NMR)spectroscopy and scanning electron microscopy(SEM).Biosensor evaluation and characterization of the inclusion complex indicated that atomoxetine HCl could actively react with 2-hydroxypropyl-β-cyclodextrin. | Shuying Li Ying Zhang Abdur Rauf Khan Shuwang He Yingxin Wang Jiangkang Xu Guangxi Zhai | 2020 | Asian Journal of Pharmaceutical Sciences2020，15，4： | 2 |
| 2 | Bioassay-guided isolation of novel and selective urease inhibitors from Diospyros lotus显示文摘Two new dimeric naphthoquinones, 5′,8′-dihydroxy-6,6′-dimethyl-7,3′-binaphthyl-1,4,1′,4′-tetraone(1; Di-naphthodiospyrol D) and 5′,8′-dihydroxy-5,8-dimethoxy-6,6′-dimethyl-7,3′-binaphthyl-1,4,1′,4′-tetraone(2; Di-naphthodiospyrol E), along with known naphthoquinones diospyrin(3) and 8-hydroxy diospyrin(4) were isolated from the chloroform fraction of extract of Diospyros lotus roots. Their structures were elucidated by advanced spectroscopic analyses, including HSQC, HMBC, NOESY, and J-resolved NMR experiments. The fractions and compounds 1-4 were evaluated for urease activity and phosphodiesterase-Ⅰ, carbonic anhydrase-Ⅱ and α-chymotrypsin enzyme inhibitory activities. Compounds 1 and 2 and their corresponding fractions showed significant and selective inhibitory effects on urease activities. The IC_(50) values of 1 and 2 were 260.4 ± 6.37 and 381.4 ± 4.80 μmol·L-1, respectively, using thiourea(IC_(50) = 21 ± 0.11 μmol·L^(-1)) as the standard inhibitor. This was the first report demonstrating that the naphthoquinones class showed urease inhibition. | Abdur Rauf Ghias Uddin Bina S. Siddiqui Ajmal Khan Umar Farooq Farhan A. Khan Syed Majid Bukhari Sher Bahadar Khan | 2017 | Chinese Journal of Natural Medicines2017，15，11： | 2 |
| 3 | On the radar frequency dependence of polar mesosphere summer echoes显示文摘Polar mesosphere summer echoes(PMSEs)are very strong radar echoes in the polar mesopause in local summer.Here we present the frequency dependence of the volume reflectivity and the effect of energetic particle precipitation on modulated PMSEs by using PMSEs observations carried out by European Incoherent SCATter(EISCAT)heating equipment simultaneously with very high frequency(VHF)radar and ultra high frequency(UHF)radar on 12 July 2007.According to the experimental observations,the PMSEs occurrence rate at VHF was much higher than that at UHF,and the altitude of the PMSEs maximum observed at VHF was higher than that at UHF.Overlapping regions were observed by VHF radar between high energetic particle precipitation and the PMSEs.In addition,highfrequency heating had a very limited impact on PMSEs when the UHF electron density was enhanced because of energetic particle precipitation.In addition,an updated qualitative method was used to study the relationship between volume reflectivity and frequency.The volume reflectivity was found to be inversely proportional to the fourth power of radar frequency.The theoretical and experimental results provide a definitive data foundation for further analysis and investigation of the physical mechanism of PMSEs. | ShuCan Ge HaiLong Li Lin Meng MaoYan Wang Tong Xu Safi Ullah Abdur Rauf Abdel Hannachid | 2020 | Earth and Planetary Physics2020，4，6： | 2 |
| 4 | Sedative and antinociceptive activities of two new sesquiterpenes isolated from Ricinus communis显示文摘Two new sesquiterpenes, trivially named ricinusoids A(1) and ricinusoids B(2), were isolated from ethyl acetate fraction of Ricinus communis. The structures of new compounds were elucidated by detailed spectroscopic techniques, including 1 D-and 2 D-NMR, UV, IR spectroscopy, and mass spectrometry. The compounds(1-2) were also assessed for in-vivo sedative and analgesic like effects in open field and acetic acid induced writhing tests respectively at 5, 10, and 20 mg·kg^(–1) i.p. Pretreatment of both test compounds caused significant(P ≤ 0.05) reduction in locomotive activity like sedative agents and abdominal constrictions like analgesics. Both compounds(1-2) possessed marked sedative and antinociceptive effects in animal models. | Umar Farooq Ajmal Khan Sadia Naz Abdur Rauf Haroon Khan Afsar Khan Irfan Ullah Syed Majid Bukhari | 2018 | Chinese Journal of Natural Medicines2018，16，3： | 2 |
| 5 | Anti-nociceptive, anti-inflammatory and sedative activities of the extracts and chemical constituents of Diospyros lotus L.显示文摘 | Ghias Uddin Abdur Rauf Bina S. Siddiqui Naveed Muhammad Ajmal Khan Syed Uzair Ali Shah | 2014 | Phytomedicine2014，，： | 1 |
| 6 | Investigation of PMSE echoes characteristics using the discontinuous EISCAT UHF observation and its relation with space environment显示文摘The observations of Polar Mesosphere Summer Echoes (PMSE) were carried out using the sporadic data of EISCAT UHF radar during the summer season from 2004 to 2015. There were 25 h of PMSE echoes with EISCAT UHF radar. PMSE echoes were mostly observed only during the early morning and fore-noon time. Moreover, the PMSE echoes are positively correlated with Lymanα radiation, but the correlation is non-significant. The occurrence of PMSE echoes in the early morning and fore-noon time and there positive correlation with Lymanαradiation suggests that solar radiations might be one important factor for PMSE echoes in this study. Very weak positive, but statistically non-significant correlation is found between PMSE occurrence rate and the local geomagneticK-indices. It is found that there is a matching between the variation in the occurrence rate of PMSE and noctilucent clouds (NLC) up to some extent and they are positively correlated. This positive correlation might support the earlier proposed idea about the role of ice particle size in producing PMSE echoes at higher frequencies. | Abdur RAUF LI Hailong Safi ULLAH WANG Maoyan MENG Lin | 2019 | Advances in Polar Science2019，30，2： | 1 |
| 7 | PMSE dependence on frequency observed simultaneously with VHF and UHF radars in the presence of precipitation显示文摘Using PMSE(polar mesosphere summer echoes) observations in combination with particle flux measurements obtained with detectors onboard the Geostationary Operational Environmental Satellite(GOES) a special condition is shown for the occurrence of rare observed UHF PMSE.When electron flux observed from GOES satellites show a decrease, then after being in the presence of precipitation UHF PMSE occurs. The heating effect on PMSE is small when the UHF electron density is enhanced at 90 km due to particle precipitation. We analyzed and compared the frequency dependence of PMSE under the condition of high energy particle precipitation in July of 2004 and 2007 at well separated frequencies(224 and 930 MHz) at the same site, height, and time. The frequency index varies with height and time. At different heights, the maximum as well as the minimum value of volume reflectivity at VHF is greater than that at UHF with 2 to 3 orders of magnitude. A new qualitative method for the analysis of dust distribution is used by analyzing the relationship between volume reflectivity and frequency index. In agreement with the results of the model it is shown that dust particles of smaller size generally did not occur at the edges, instead they occurred in the middle PMSE regions. | Safi ULLAH 李海龙 Abdur RAUF 蒙林 王彬 王茂琰 | 2018 | Plasma Science and Technology2018，20，11： | 1 |
| 8 | In vivo sedative and muscle relaxants activity of Diospyros lotus L显示文摘Objective: To evaluate the sedative effect of Diospyros lotus L(D. lotus) extract in mice using the open field and Rota rod tests.Methods: For the sedative and muscle relaxants activities of extract/fractions of the plant, invivo open field and phenobarbitone-induced sleeping time were used, while the Roda rod test was employed in animals for the assessment of muscle relaxant activity.Results: Results from this investigation revealed that the extracts of D. lotus have exhibited significant sedative effect in mice(45.98%) at 100 mg/kg i.p. When the extract was partitioned with different solvents, the n-hexane fraction was inactive whereas the chloroform fraction was the most active with 82.67% sedative effect at 50 and 100 mg/kg i.p. On the other hand,the ethyl acetate and n-butanol fractions displayed significant sedative effects(55.65% and40.87%, respectively) at 100 mg/kg i.p. Among the tested extract/fractions, only chloroform and ethyl acetate fractions showed significant(P < 0.05) muscle relaxant activity in the Rota rod test.Conclusions: In short, our study provided scientific background to the traditional uses of D.lotus as sedative. | Abdur Rauf Ghias Uddin Bina Shaheen Siddiqui Haroon Khan | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，4： | 1 |
| 9 | Effect of reinforcement corrosion on bond strength显示文摘 | Almusallam Abdullah A Al-Gahtani Ahmad S Aziz Abdur Rauf and Rasheeduzzafart | 1996 | Construction and Building Materials1996，10，2： | 1 |
| 10 | Numerical Analysis of Artificial Electron Heating Effects on Polar Mesospheric Winter Echoes显示文摘In this paper,an analytical model is used to analyze the modulated polar mesospheric winter echoes(PMWE).The winter parameters were introduced to simulate the effects of different parameters during the artificial electron heating of PMWE.The important role of the charged dust particle in the creation of PMWE is confirmed again.It is found that during the heating of PMWE,the increases of the dust size,dust charge,electron temperature,initial electron density,and ion-neutral collision frequency cause the increase of the electron density irregularity,and hence the PMWE strength.However,with increasing the dust density,the electron density irregularity and the PMWE strength decrease. | Safi Ullah Hai-Long Li Abdur Rauf Lu-Yao Fu Mao-Yan Wang Lin Meng | 2020 | Journal of Electronic Science and Technology2020，18，3： | 1 |
| 11 | Three new anthraquinone derivatives isolated from Symplocos racemosa and their antibiofilm activity显示文摘Three new alkyl substituted anthraquinone derivatives, trivially named as symploquinones A-C(Compounds 1-3) were isolated from Symplocos racemosa. The structures of these compounds were determined on the basis of extensive spectroscopic analyses(UV, IR, Mass, ~1 H-and ^(13)C-NMR, and two-dimensional(2D) NMR techniques). The resulting data were also compared with the reported literature. These compounds were then subjected to antibacterial or antibiofilm testing. Compounds 1 and 3 exhibited good antibacterial activity in the concentration range of 160-83 μg·m L^(-1) against Streptococcus mutans, methicillin resistant Staphylococcus aureus and Proteus mirabilis. Both compounds were further screened for anti-biofilm activity, which revealed promising activities at sub-MIC concentrations. None of the compounds were found to be active against Klebsiella pneumoniae. | Umar Farooq Sara Khan Sadia Naz Ajmal Khan Afsar Khan Ayaz Ahmed Abdur Rauf Syed Majid Bukhari Shujaat Ali Khan Arfa Kamil Nadia Riaz Abdur Rahman Khan | 2017 | Chinese Journal of Natural Medicines2017，15，12： | 0 |
| 12 | Scandix pecten-veneris L.的植物素、生物学潜力及酶抑制活性研究(英文)显示文摘目的:本研究旨在测定Scandix pecten-veneris L.的植物素和评价其生物学潜力。方法:测定S.pecten-veneris提取物中植物素的含量,包括生物碱、黄酮、多酚和单宁。使用2,2-二苯基-1-苦肼基(DPPH)测定抗氧化活性;同时通过铁还原/抗氧化能力(FRAP)测定还原能力;使用琼脂扩散测定法评价对七种细菌和四种真菌菌株的抗微生物活性。同时,对脲酶、磷酸二酯酶-Ⅰ和过氧化氢酶-Ⅱ进行酶抑制研究。结论:沙门氏菌显示出适度的抗自由基活性;羟基自由基的潜能降至初始值的20%左右。S.pectenveneris多种提取物的抗氧化活性与总酚含量呈线性相关。S.pecten-veneris叶对金黄色葡萄球菌表现出最高的抑制活性;对白色念珠菌表现出到最高的抗真菌活性。植物提取物对脲酶的活性最有效;对磷酸二酯酶-Ⅰ和碳酸酐酶-Ⅱ显示出中等活性。结果表明,S.pecten-veneris具有良好的药用潜力,可用于治疗一些特定的疾病。 | Abdul WAHAB Syed Aleem JAN Abdur RAUF Zia ur REHMAN Zahid KHAN Aftab AHMED Fatima SYED Sher Zaman SAFI Hamayun KHAN Muhammad IMRAN | 2018 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2018，19，2： | 0 |
| 13 | 极区中层尘埃粒子的带电效应显示文摘利用轨道运动限制和尘埃带电理论,分析了在极区中层顶中,尘埃等离子体受高功率无线电磁波的影响下,尘埃粒子的带电效应。此外,利用数值模拟及实验方法对理论分析结果进行了验证。通过理论分析可知,尘埃粒子带电数由尘埃半径大小、电子温度、离子温度的高低以及离子数密度和电子数密度决定。通过数值模拟及统计分析火箭探测数据得到,平均尘埃带电数随等离子体中尘埃电荷数密度的增加而降低,而随尘埃半径、电子温度和电子密度的增加而增加。在一定程度上,仿真及实验结果与理论研究结果较一致,当尘埃带电量为0.4e时,尘埃半径值与文献结果一致。 | 葛淑灿 李海龙 蒙林 王茂琰 RAUF Abdur ULLAH Safi | 2021 | 电子科技大学学报2021，50，4： | 0 |
| 14 | In vitro biological screening of the stem of Desmodium elegans显示文摘Objective:To explore the medicinal importance of the stem of Desmodium elegans,methanolic extract,and its different solvent fractions were evaluated for brine shrimp lethality,insecticidal and phytotoxicity,antifungal,and antibacterial activities.Methods:The methanolic extract and its solvent fractions were tested for cytotoxic,phytotoxic,insecticidal,antifungal,and antibacterial effects using our previous published protocols.Results:The methanolic,DCM,ethyl acetate and n-butanol fractions exhibited insecticidal effect against Callosobruchus analis and Rhyzopertha dominie.The methanolic extract,n-hexane,DCM ethyl acetate and n-butanol showed 75,85,85,65 and 5%phytotoxicity at the tested concentration of 500μg/ml.respectively.The solvent fractions(DCM and ethyl acetate)were effective against F.solani(10%and 20%,inhibition respectively).All the tested samples were devoid of cytotoxic and antibacterial effects.Conclusions:It was concluded diat diis plant can be practiced for control of weeds and insects. | Arshad Khan Rabia Usman Ming-Liang Wang Abdur Rauf Naveed Muhammad Akhatar Aman Taha Hussein Musa Tahir | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，9： | 0 |
| 15 | 基于新型数据分析软件的极区中层强雷达回波研究显示文摘该文利用极区中层异常回波及云粒子数据提取分析软件(PMEC_DEAS)处理雷达回波及云粒子数据集,并进行回波特性研究。以通过PMEC_DEAS分析的短期和长期极地中层夏季回波(polar mesosphere summer echoes,PMSE)和极地中层云(polar mesospheric clouds,PMC)数据为例,研究了PMSE出现率与PMC之间的相关性。研究发现短期的PMSE出现率和PMC之间的相关性不显著,长期的双层PMSE出现率与PMC之间呈正相关关系。这表明双层PMSE与PMC密切相关,这与现有的结论一致。以此可以看出,PMEC_DEAS可以有效地适应所研究事件的复杂特征变化,并具有良好的鲁棒性。此外,利用PMEC_DEAS软件分析所得的数据具有更好的稳定性和兼容性,与目前的主流数据分析软件相比更具便捷性和实用性。 | 葛淑灿 李海龙 蒙林 RAUF Abdur ULLAH Safi | 2021 | 电子科技大学学报2021，50，6： | 0 |
| 16 | Comparison of the reaction of polar mesosphere winter echoes and polar mesosphere summer echoes to high-frequency heating in terms of modulated characteristics显示文摘In this work,for the first time,we have analyzed and compared the responses of polar mesosphere winter echoes(PMWE)and their summer counterpart,polar mesosphere summer echoes(PMSE),to high-frequency(HF)heating in terms of modulated characteristics(i.e.,backscatter intensity reduction,recovery,and overshoot).Both PMWE and PMSE observations were from the same site(Tromsφ,Norway;69.6°N,19.2°E)and radar(EISCAT[European Incoherent Scatter Scientific Association]very high frequency,224 MHz).The heating patterns of both PMWE and PMSE were found to be similar;however,PMSE was more greatly affected by HF heating.Polar mesosphere summer echoes showed recovery and overshoot more frequently than did PMWE.In addition,the mean recovery and overshoot of PMSE were greater than those of PMWE.The associated electron temperature enhancement was estimated for both PMWE and PMSE and showed that,compared with PMWE,the electron temperature enhancement was more significant in PMSE.The strong heating effects on PMSE may be due to the considerable increase in electron temperature. | Safi Ullah HaiLong Li Abdur Rauf Shahid Ullah Khan Sufyan Ullah Khan ShuCan Ge Bin Wang MaoYan Wang Lin Meng | 2023 | Earth and Planetary Physics2023，7，2： | 0 |
| 17 | Influence of Ni/Mn ratio on magnetostructural transformation and magnetocaloric effect in Ni48-xCo2Mn38+xSn12(x=0,1.0,1.5,2.0,and 2.5)ferromagnetic shape memory alloys显示文摘An investigation on the magnetostructural transformation and magnetocaloric properties of Ni_(48-x)Co_2Mn_(38+x)Sn_(12)(x = 0, 1.0, 1.5, 2.0, and 2.5) ferromagnetic shape memory alloys is carried out. With the partial replacement of Ni by Mn in the Ni_(48)Co_2Mn_(38)Sn_(12) alloy, the electron concentration decreases. As a result, the martensitic transformation temperature is decreased into the temperature window between the Curie-temperatures of austenite and martensite. Thus, the samples with x = 1.5 and 2.0 exhibit the magnetostructural transformation between the weak-magnetization martensite and ferromagnetic austenite at room temperature. The structural transformation can be induced not only by the temperature,but also by the magnetic field. Accompanied by the magnetic-field-induced magnetostructural transformation, a considerable magnetocaloric effect is observed. With the increase of x, the maximum entropy change decreases, but the effective magnetic cooling capacity increases. | Ishfaq Ahmad Shah Najam ul Hassan Abdur Rauf 刘俊 龚元元 徐桂舟 徐锋 | 2017 | Chinese Physics B2017，26，9： | 0 |
| 18 | Reversal of multidrug resistance and antitumor promoting activity of 3-oxo-6β-hydroxy-β-amyrin isolated from Pistacia integerrima显示文摘The bioactive triterpenoid 3-oxo-6-β-hydroxy-β-amyrin(1)has been isolated from multiple plant sources.In this study,chloroform fraction of Pistacia integerrima extract was processed for the isolation of the compound.The compound identity was confirmed by advanced spectroscopy technique.X-ray crystallography was applied for molecular structure confirmation.In addition,compound 1 was screen for its activity on reversal of MDR(multidrug resistance)mediated by P-gp(P-glycoprotein).This was accomplished by using rhodamine123 exclusion on multidrug-resistant human ABCB1 gene transfected mouse T-lymphoma cell line.Outcomes revealed that MDR reversing effect was comparable to verapamil as positive control in vitro.Treatment of TPA-induced tumor promotion with 3-oxo-6β-hydroxy-β-amyrin led to reduction in the applied anti-tumor promotion experiment.The chemo-preventive effect of 3-oxo-6β-hydroxy-β-amyrin was comparable to curcumin as positive control based on the reduction of immediate early tumor antigen expression.Molecular docking by applying Autodock Vina 1 and i-GEMDOCK v 2.1 tools indicated that compound 1 gives good docking results,as determined by their fitness score and specificity.Moreover,results showed that compound 1 isolated from Pistacia integerrima precisely attached to a region where co-crystallized ligand for receptor previously existed.Our findings may explain the use of Pistacia integerrima plant extracts as an anticancer agent in folk medicine. | ABDUR RAUF SAUD BAWAZEER MUSLIM RAZA EMAN EL-SHARKAWY MD.HABIBUR RAHMAN MOHAMED A.EL-ESAWI GHIAS UDDIN BINA SSIDDIQUI ANEES AHMED KHALIL JOSEPH MOLNAR AKOS CSONKA DIÁNA SZABÓ HAROON KHAN MOHAMMAD SMUBARAK TAIBI BEN HADDA MUDYAWATI KAMARUDDIN SEEMA PATEL | 2021 | BIOCELL2021，45，1： | 0 |
| 19 | Characteristic analysis of layered PMSEs measured with different elevation angles at VHF based on an experimental case显示文摘Polar Mesosphere Summer Echoes(PMSEs)are very strong radar echoes observed at altitudes near the polar summer mesopause.One of the essential properties of these radar echoes is that they can give useful diagnostic information about the physics of the scattering process.In this paper,the related characteristics of PMSEs measured with the European Incoherent SCATter Very High Frequency(EISCAT VHF)224 MHz radar on 13–15 July 2010 are studied at different elevation angles from 78°to 90°.It is found that the PMSEs peak power and strongest PMSEs average power occur at the same elevation angles.Also interesting is that the strongest PMSEs occur at off-vertical angles when a PMSEs has a layered(multilayer)structure.And reflection may have more significant effects on PMSEs when there are double or multilayer PMSEs.Possible explanations regarding these observations are discussed. | ShuCan Ge HaiLong Li Bin Xu Tong Xu Lin Meng MaoYan Wang Abdel Hannachi MengYan Zhu Lina Broman Safi Ullah Abdur Rauf | 2021 | Earth and Planetary Physics2021，5，1： | 0 |
| 20 | Oral administration of Moringa oleifera leaf powder relieves oxidative stress,modulates mucosal immune response and cecal microbiota after exposure to heat stress in New Zealand White rabbits显示文摘Background:Heat stress(HS)disrupts the gut barrier allowing the uptake of lipopolysaccharide(LPS)and leads to an inflammatory response and changes in gut microbiota composition.Moringa oleifera leaf powder(MOLP)has been proposed to combat HS,yet its alleviate role is currently under investigation.The current study investigated the effects of chronic HS and MOLP supplementation on changes in redox status and immune response of cecal mucosa along with alteration in cecal microbiota.Methods:A total of 21 young New Zealand White(NZW)rabbits(male)about 32 weeks old(mean body weight of 3318±171 g)reared on a commercial pelleted diet were employed;divided into three groups(n=7):control(CON,25°C),heat stress(HS,35°C for 7 h daily),and HS supplemented orally with MOLP(HSM,35°C)at 200 mg/kg body weight per day for 4 weeks.Results:The results demonstrated that MOLP supplementation increased organ index of cecal tissue compared with the HS group(P>0.05).Levels of malonaldehyde(MDA)and activity of superoxide dismutase(SOD)as well as lactate dehydrogenase(LDH)were reduced in the cecal mucosa of the HSM group compared with the HS group.MOLP downregulated the contents of cecal mucosa LPS,several inflammatory markers(TNF-α/IL-1α/IL-1β),and myeloperoxidase(MPO)in the HSM group(P<0.05).Secretory immunoglobulin A(SIgA)was increased in the HSM group compared with the HS group(P<0.05).The transcriptome of cecal mucosa showed that MOLP reduced gene expression relative to several immune factors,including IL-10,IFNG,and RLA,whereas both HS and MOLP increased the gene expression of fat digestion and absorption pathway,including APOA1,FABP1,FABP2,MTTP,andLOC100344166,compared to the CON group(P<0.001).At the phylum level,the relative abundance of Proteobacteria was increased by HS,while Actinobacteria was significantly increased by HSM compared to other groups(P<0.05).At genus level,Papillibacter was higher in abundance in HSM groups compared to CON and HS groups(P<0.05).Higher butyrate concentrations were observed in the HSM group than HS and CON groups(P<0.05).Conclusion:In conclusion,HS in growing rabbits resulted in alteration of cecal microbiota at phyla level as well as increased oxidative stress and expression of mucosal inflammatory genes.Whereas,oral MOLP supplementation elevated the relative weight of cecum,affected their immunological and cecal micro-ecosystem function by improving antioxidant status and down-regulating mucosal tissue inflammatory response. | Talat Bilal Yasoob Defu Yu Abdur Rauf Khalid Zhen Zhang Xiaofeng Zhu Heba M.Saad Suqin Hang | 2021 | Journal of Animal Science and Biotechnology2021，12，4： | 0 |
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