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| 1 | Adaptive guidance law design based on characteristic model for reentry vehicles显示文摘In this paper an adaptive guidance law based on the characteristic model is de-signed to track a reference drag acceleration for reentry vehicles like the Shuttle. The characteristic modeling method of linear constant systems is extended for single-input and single-output (SISO) linear time-varying systems so that the characteristic model can be established for reentry vehicles. A new nonlinear dif-ferential golden-section adaptive control law is presented. When the coefficients belong to a bounded closed convex set and their rate of change meets some con-straints, the uniformly asymptotic stability of the nonlinear differential golden-sec- tion adaptive control system is proved. The tracking control law, the nonlinear differential golden-section control law, and the revised logical integral control law are integrated to design an adaptive guidance law based on the characteristic model. This guidance law overcomes the disadvantage of the feedback lineariza-tion method which needs the precise model. Simulation results show that the proposed method has better performance of tracking the reference drag accel-eration than the feedback linearization one. | YANG JunChun HU Jun NI MaoLin | 2008 | Science in China(Series F)2008，51，12： | 12 |
| 2 | Research on Low Cycle Fatigue Reliability-based Robust Design Optimization of Turbine Blade显示文摘针对涡轮叶片低周疲劳可靠性稳健设计优化问题,对叶片材料进行了高温疲劳试验,采用定量方程随机化方法处理试验数据,获得叶片材料的概率-应变-寿命曲线。采用贝塞尔曲线描述叶片型线方程,建立了涡轮叶片结构及流场的参数化模型,采用热-流-固耦合有限元法对涡轮流场和叶片进行了数值分析,得到叶片动能效率和应力应变分布特性。建立了叶片疲劳可靠性稳健设计优化模型,并采用响应面法获得叶片结构性能函数和极限状态函数,将叶片低周疲劳可靠性作为基本约束条件,采用序列二次规划优化法得到设计优化结果。研究结果表明,优化后的叶片低周疲劳可靠性以及稳健性显著提高,模型及方法正确可行,可用于涡轮叶片以及其他复杂结构的低周疲劳可靠性稳健设计优化。 | PENG Maolin YANG Zichun CAO Yueyun CHU Zhuli | 2013 | 中国电机工程学报2013，33，11： | 8 |
| 3 | New advances in in-situ thermal desorption technology for contaminated soil显示文摘With the development of ecological civilization and economic construction,remediation of contaminated soils has caused more and more concern of scientists and engineers.Situ thermal desorption is a mature and effective technology which is especially suitable for the contaminated soil of relocated chemical plant[1,2],Compared with in-situ chemical oxidation and ectopic thermal desorption,the in-situ thermal desorption has stronger applicability and higher repair efficiency.The main applications of the in-situ thermal desorption technology are semi-volatile and volatile organic pollutants. | SHI Yan LUO ZiHao WANG YiXuan CAI MaoLin YANG LiMan | 2019 | Science China(Technological Sciences)2019，62，11： | 7 |
| 4 | Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332显示文摘Dear Editor,Since December 2019,the pandemic of coronavirus disease 2019(COVID-19)has taken a heavy toll on global health,creating an urgent need to develop effective strategies for prevention and treatment.The etiological agent,known as severe acute respiratory syndrome coronavirus 2(SARSCoV-2),has infected nearly 229.2 million people worldwide with more than 4.7 million deaths as of September 15,2021.Older age and preexisting health conditions are associated with worse clinical prognosis including higher mortality rates(Zhou et al.,2020).The global race to combat this pandemic has led to rapid deployment of numerous effective vaccines against SARS-CoV-2(Tregoning et al.,2021).However,the emergence of viral variants,including the Delta variant(B.1.617.2),compromised vaccine effectiveness with resurgence of SARS-CoV-2 infection among highly vaccinated population(Keehner et al.,2021).Therefore,development of therapeutics against the more conserved viral targets would be essential to contain the spread of COVID-19 and reduce mortality. | Yao Zhao Chao Fang Qi Zhang Ruxue Zhang Xiangbo Zhao Yinkai Duan Haofeng Wang Yan Zhu Lu Feng Jinyi Zhao Maolin Shao Xiuna Yang Leike Zhang Chao Peng Kailin Yang Dawei Ma Zihe Rao Haitao Yang | 2022 | Protein & Cell2022，13，9： | 6 |
| 5 | Plant microremains provide direct evidence for the functions of stone knives from the Lajia site, northwestern China显示文摘A large number of stone knives have been recovered from Neolithic archaeological sites in East Asia.However, direct evidence regarding the functions of the stone knives has been scarce, and hence, their functions have remained controversial. In this study, we recovered and analysed ancient starch grains and phytoliths from residues adhering to stone knives excavated from the Lajia site, Qinghai Province, northwest China, thus providing direct evidence for the functions of the knives. Our analyses were based on the following:(1) an assemblage of 278identifiable starch grains, representing grains from the stems of foxtail millet(Setaria italica) and broomcorn millet(Panicum miliaceum)(65.1 % of the total) and the stems of Hordeum and Triticum species(3.6 % of the total), and(2) an assemblage of 361 identifiable phytoliths,the majority of which were from the stems and leaves of plants such as Panicoideae and related taxa(96 % of the total). Our study demonstrates that one of the functions of the stone knives was the harvesting crops. In addition, a few starch grains from food legumes and roots(3.4 % of the total) indicate that the stone knives were also likely used to process, peel and cut some foods. | Zhikun Ma Quan Li Xiujia Huan Xiaoyan Yang Jingyun Zheng Maolin Ye | 2014 | Chinese Science Bulletin2014，59，11： | 5 |
| 6 | Bone morphogenetic proteins:Relationship between molecular structure and their osteogenic activity显示文摘Bone morphogenetic proteins(BMPs)are a family of potent,multifunctional growth factors belonging to transforming growth factor-(TGF-).They are highly conservative in structures.Over 20 members of BMPs with varying functions such as embryogenesis,skeletal formation,hematopoiesis and neurogenesis have been identified in human body.BMPs are unique growth factors that can induce the formation of bone tissue individually.BMPs can induce the differentiation of bone marrow mesenchymal stem cells into osteoblastic lineage and promote the proliferation of osteoblasts and chondrocytes.BMPs stimulate the target cells by specific membrane-bound receptors and signal transduced through mothers against decapentaplegic(Smads)and mitogen activated protein kinase(MAPK)pathways.It has been demonstrated that BMP-2,BMP-4,BMP-6,BMP-7,and BMP-9 play an important role in bone formation.This article focuses on the molecular characterization of BMPs family members,mechanism of osteogenesis promotion,related signal pathways of osteogenic function,relationships between structure and osteogenetic activity,and the interactions among family members at bone formation. | Jian Yang Pujie Shi Maolin Tu Yun Wang Meng Liu Fengjiao Fan Ming Du | 2014 | Food Science and Human Wellness2014，3，3： | 4 |
| 7 | Designing for Long Campaign Life Blast Furnace (2)-The Simulation of Temperature Field of Lining and Cooling Apparatus显示文摘Through the numerical modeling of temperature field for Blast Furnace (BF) lining and stave coolers, it can tell designers how to design a cooler which the hot surface temperature is less than its critical temperature under very high heat flux. Applying low heat re- sistance lining and staves cooler to BF is good for a layer of slag skull frozen on the hot surface of cooling stave. As long as the slag skull can stand, the furnace wall is stable and the heat loss of furnace does not increase. This is the basic principle for designing long campa- ignship BF. | Qingguo Xue Weiguo Yang Susen Cheng Maolin Wu Tianjun Yang Metallurgy School, University of Science and Technology Beijing, Beijing 100083, China The Center of Engineering and Research for Iron and Steel, 100053, China | 2000 | International Journal of Minerals,Metallurgy and Materials2000，14，1： | 3 |
| 8 | Hepatitis B virus hijacks CTHRC1 to evade host immunity and maintain replication显示文摘HepatitisBvirus(HBV)infection causes acuteand chronic liver diseases,but is not directly cytopathic.Liver injury results fromrepeated attempts of the cellular immune response system to control the viral infection.Here,we investigate the roles of cellular factors and signaling pathways involved in the regulation of HBV replication to reveal the mechanism underlying HBV infection and pathogenesis.Weshowthat collagen triple helix repeat containing 1(CTHRC1)expression is elevated in HBV-infected patients andin HBV-transfected cells through epigenetic modification and transcriptional regulation.CTHRC1 facilitates HBV replication in cultured cells and BALB/c mice by activating the PKCa/ERK/JNK/c-Jun cascade to repress the IFN/JAK/STAT pathway.HBV-activated CTHRC1 downregulates the activityof typeI interferon(IFN),theproductionof IFN-stimulatedgenes(ISGs),andthephosphorylationofsignal transducerandactivator of transcription 1/2(STAT1/2),whereas it upregulates the phosphorylation and ubiquitination of type I IFN receptors(IFNARa/b).Thus,our results showthat HBV uses a novelmechanismto hijack cellular factors and signal cascades in order to evade host antiviral immunity and maintain persistent infection.We also demonstrate that CTHRC1 has a novel role in viral infection. | Lan Bai Wei Zhang Li Tan Hongchuan Yang Maolin Ge Chengliang Zhu Rui Zhang Yanhua Cao Junbo Chen Zhen Luo Wenzhe Ho Fang Liu Kailang Wu Jianguo Wu | 2015 | Journal of Molecular Cell Biology2015，7，6： | 2 |
| 9 | Rce1 expression in renal cell carcinoma and its regulatory effect on 786-O cell apoptosis through endoplasmic reticulum stress显示文摘(Rce1 ) 地岬和 a-factor-converting 酶 1 位于 endoplasmic 蜂窝胃(嗯) 并且被认为为绝大多数 CAAX 蛋白质处理的 endoproteolytic 负责。Endoplasmic 蜂窝胃应力(ERS ) 在肾的房间癌(RCC ) 起一个重要作用;然而,在 RCC 的 Rce1 的表示和角色广泛地没被学习。我们试图在 RCC 786-O 房间在嗯导致 apoptosis 在 RCC 纸巾和它的分子的机制调查 Rce1 的表示。我们首先使用了检测在肾的癌纸巾和 paracancerous 纸巾的 Rce1 表示的西方的弄污,量的反向的 transcriptase 聚合酶链反应,和 immunohistochemistry。Rce1 表示是在 RCC 的 upregulated,这被发现纸巾,和它的积极表示水平强烈与 clinicopathologic 特征被联系。下次,我们在人的胚胎的肾房间线 HEK293 和人的肾的癌房间线 786-O 检测了 Rce1 的表示, ACHN,和 A498。Rce1 的更高的表示在人的肾的癌房间线被发现,特别在 786-O 房间。在 786-O 房间的 Rce1 击倒增加的 apoptosis | Jianjun Li Delin Wang Junnan Liu Yunlang Qin Liangliang Huang Qiangfeng Zeng Maolin Xiao Jie Hu Qixin Yang Jiang He Li Mai Ying Li Wujiang Liu | 2017 | Acta Biochimica et Biophysica Sinica2017，49，3： | 2 |
| 10 | Earliest domestication of common millet(Panicummiliaceum)in East Asia extended to 10 000 years ago显示文摘 | Houyuan Lu Jianping Zhang Kam-biu Liu Naiqin Wu Yumei Li Kunshu Zhou Maolin Ye Tianyu Zhang Hai-jiang Zhang Xiaoyan Yang Licheng Shen Deke Xu Quan Li | 2009 | PNAS2009，106，18： | 1 |
| 11 | Earliest domestication of common millet(Panicummiliaceum)in East Asia extended to 10 000 years ago 显示文摘 | Houyuan Lu Jianping Zhang Kam-biu Liu Naiqin Wu Yumei Li Kunshu Zhou Maolin Ye Tianyu Zhang Hai-jiang Zhang Xiaoyan Yang Licheng Shen Deke Xu Quan Li | 2009 | Proceedings of the National Academy of Sciences of the Unit-ed States of America2009，106，： | 1 |
| 12 | Millet noodles in Late Neolithic China显示文摘 | Lü Houyuan Yang Xiaoyan Ye Maolin | | 0，，： | 1 |
| 13 | Millet noodles in Late Neolithic China显示文摘 | Lu Houyuan Yang Xiaoyan Ye Maolin | 2005 | Nature2005，437，： | 1 |
| 14 | DeceFL:a principled fully decentralized federated learning framework显示文摘Traditional machine learning relies on a centralized data pipeline for model training in various applications;however,data are inherently fragmented.Such a decentralized nature of databases presents the serious challenge for collaboration:sending all decentralized datasets to a central server raises serious privacy concerns.Although there has been a joint effort in tackling such a critical issue by proposing privacy-preserving machine learning frameworks,such as federated learning,most state-of-the-art frameworks are built still in a centralized way,in which a central client is needed for collecting and distributing model information(instead of data itself)from every other client,leading to high communication burden and high vulnerability when there exists a failure at or an attack on the central client.Here we propose a principled decentralized federated learning algorithm(DeceFL),which does not require a central client and relies only on local information transmission between clients and their neighbors,representing a fully decentralized learning framework.It has been further proven that every client reaches the global minimum with zero performance gap and achieves the same convergence rate O(1=T)(where T is the number of iterations in gradient descent)as centralized federated learning when the loss function is smooth and strongly convex.Finally,the proposed algorithm has been applied to a number of applications to illustrate its effectiveness for both convex and nonconvex loss functions,time-invariant and time-varying topologies,as well as IID and Non-IID of datasets,demonstrating its applicability to a wide range of real-world medical and industrial applications. | Ye Yuan Jun Liu Dou Jin Zuogong Yue Tao Yang Ruijuan Chen Maolin Wang Chuan Sun Lei Xu Feng Hua Yuqi Guo Xiuchuan Tang Xin He Xinlei Yi Dong Li Guanghui Wen Wenwu Yu Hai-Tao Zhang Tianyou Chai Shaochun Sui Han Ding | 2023 | National Science Open2023，2，1： | 1 |
| 15 | Improvement of multiple oxide properties:effect of gel processes on the quality of Bi2Sr2Ca Cu2O8+δsuperconducting powders显示文摘 | Zhang Ying Yang Huazhe Li Maolin | 2010 | Cryst Comm Eng2010，12，： | 1 |
| 16 | Millet noodles in Late Neolithic China显示文摘 | Lu Houyuan Yang Xiaoyan Ye Maolin | 2005 | Nature2005，，437： | 1 |
| 17 | Double-strand hydrolysis of DNA by a magnesium(II) complex with diethylenetriamine显示文摘 | Pin Yang Rui Ren Maolin Guo Aixin Song Xiangli Meng Caixia Yuan Qinghua Zhou Huili Chen Zhenhai Xiong Xiaoli Gao | 2004 | JBIC Journal of Biological Inorganic Chemistry2004，，4： | 1 |
| 18 | Component and simulation of the 4,000-year-old noodles excavated from the archaeological site of Lajia in Qinghai,China显示文摘Noodles are a global food,but the periods when and places where they were made and originated,as well as their ingredients and the cooking methods used to manufacture them,have remained contentious.In the 2005 edition of the journal Nature,we wrote a summary of the millet noodle specimens found in the Late Neolithic Qijia cultural stratum of the Lajia archaeological site in Qinghai Province,China.However,how the ancient people made millet noodles remains controversial.This paper provides a systematic analysis of the remains of noodles found withinan earthenware bowl at the Lajia ‘‘noodle house'' in terms of their plant composition including phytoliths,starch and biomarkers.It provides evidence of how people used millet4,000 years ago and,most specifically,of the principal methods used for producing millet-based noodles.Further,we show how we used traditional hele tools to make hele millet noodles,with especial reference to the gelatinized hydrogel-forming method,to simulate morphology consistent with the composition and form of the unearthed millet noodles.The results of this study provide new evidence and new insights into the cultural characteristics of the prehistoric human diet. | Houyuan L Yumei Li Jianping Zhang Xiaoyan Yang Maolin Ye Quan Li Can Wang Naiqin Wu | 2014 | Chinese Science Bulletin2014，59，35： | 1 |
| 19 | Pre-incubated with BSA-complexed free fatty acids alters ER stress/autophagic gene expression by carboxylated multi-walled carbon nanotube exposure in THP-1 macrophages显示文摘Recently we found that multi-walled carbon nanotube (MWCNT) exposure alters the mRNA levels of endoplasmic reticulum (ER) stress/autophagic genes, but the impact of biological molecules on this response is unclear. Herein, we compared the different actions of carboxylated MWCNTs (c-MWCNTs) pre-incubated with bovine serum albumin (BSA) or BSA-complexed free fatty acid (denoted as FFA) on macrophages derived from THP-1 monocytes (denoted as THP-1 macrophages). C-MWCNTs exhibited increased diameter and hydrodynamic size as well as decreased absolute zeta potential value after pre-incubation with BSA or FFA, which suggested a coating effect. Cytotoxicity or oxidative stress were not significantly induced after exposure to BSA-or FFA-coated c-MWCNTs. BSA-pre-incubated c-MWCNTs significantly enhanced the expression of the ER stress gene, DDIT3 and the autophagic genes, ATG5, BECN1, and PLIN2, but the mRNA levels of these genes was significantly decreased by FFA-pre-incubated c-MWCNTs. FFA-pre-incubated c-MWCNTs induced significantly higher lipid accumulation and interleukin-6 (IL-6) protein level compared with BSA-pre-incubated c-MWCNTs, which suggested that FFA-pre-incubated c-MWCNTs may more effectively induce the formation of macrophage foam cells. Collectively, our data indicated that pre-incubation with FFA may influence c-MWCNT-induced ER stress/autophagic gene expression and foam cell formation in THP-1 macrophages. | Qianyu Yang Maolin Wang Yongbing Sun Shengming Peng Yanhuai Ding Yi Cao | 2019 | Chinese Chemical Letters2019，30，6： | 1 |
| 20 | High-performance self-powered GaN/PEDOT:PSS hybrid heterojunction UV photodetector for optical communication显示文摘Self-powered ultraviolet photodetectors(UVPDs)provide great possibility for the next-generation energy conservation optical communication technology;while the high photodetection performance at zero bias is still a tremendous challenge.Herein,ntype GaN film with Si-doping concentration of~1018cm^(-3)and p-type organic PEDOT:PSS were adopted to construct a planar hybrid heterojunction via the simple spin-coating method.Profited from typical type-Ⅱenergy band alignment and giant photovoltaic effect at GaN/PEDOT:PSS inorganic-organic interface,the fabricated UVPD achieved excellent self-powered photoelectrical properties in dual-band with large R of 0.96 A/W(2.8 A/W),superior D*of 5.7×1012Jones(1.7×10^(13)Jones),prominent EQE of 325%(1371%),high on/off ratio of 9.65×10^(3)(6.15×10^(3))and fast rise/decay time of 60.7/124.5 ms(30.9/26.7 ms)for UVA(UVC)band,as well as outstanding UV/visible rejection ratio and great detection repeatability.Functioned as an optical signal receiver,this designed self-powered UVPD decoded a message of“NJUPT”from a simple optical communication system.These results open a new avenue for GaN/PEDOT:PSS heterojunction in UV communications and related applications. | LI Shan LIU Zeng ZHANG MaoLin YANG LiLi GUO YuFeng TANG WeiHua | 2024 | Science China(Technological Sciences)2024，67，2： | 0 |
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