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| 1 | 用ALV-Jgp85单克隆抗体证明蛋鸡存在J亚群禽白血病显示文摘采用免疫组化法,对病理学初步诊断为蛋用型鸡 J亚群白血病的自然发病鸡的肿瘤、骨髓、肝脏、脾脏、肾脏、肺脏、心脏、胰脏、输卵管、卵巢、腺胃、骨骼肌、大脑、坐骨神经,用特异性抗 J亚群禽白血病病毒(ALV J)囊膜糖蛋白gp85的单克隆抗体进行检测,待检的组织切片中均检出阳性抗原,免疫组化的研究结果与病理学诊断结果相一致。在国内外首次发现并报道蛋用型鸡 J亚群禽白血病的自然病例。 | 徐镔蕊 董卫星 余春明 冯小宇 李宁 Lucy F.Lee Maoxiang Li | 2005 | 畜牧兽医学报2005，36，3： | 52 |
| 2 | 蛋鸡J亚群禽白血病的分子生物学诊断显示文摘根据J亚群白血病病毒(ALV-J)原型株HPRS-103的序列设计了一对针对外源性ALV-J引物H5和H7,从发生ML病死鸡的肿瘤、骨髓、肝脏、脾脏和输卵管组织中提取DNA作为模板,经PCR扩增得到长度为545bp的片段,对其序列进行测定后,与ALV-J原型株HPRS-103的序列进行了比较,发现其核苷酸同源性为97.4%,所编码氨基酸的同源性为96.1%。该片段含有ALV-Jgp85编码基因的部分序列和ALV-Jpol基因的部分序列,从分子水平上证实了蛋鸡发生J亚群禽白血病,进一步证明了此前根据病理学观察、免疫组化及免疫荧光诊断的结果。这是首次从分子水平上证明蛋用型鸡发生J亚群禽白血病。 | 徐镔蕊 董卫星 余春明 Lucy F.Lee Maoxiang Li | 2005 | 病毒学报2005，21，4： | 39 |
| 3 | Incidence and mortality of cervical cancer in China,2013显示文摘Objective: Estimating the incidence and mortality rate of cervical cancer became necessary to establish prevention measures and healthy policies.The aim of this study was to estimate the updated incidence and mortality rate of cervical cancer in 2013 in China.Methods: According to the evaluation criteria developed by the National Central Cancer Registry of China,the data submitted from 255 cancer registries met the required standards in 2013.Cervical cancer cases were retrieved from the national database and combined with the 2013 national population data.The age-standardized incidence and mortality rates were based on the demographic structure of the national census 2000 and Segi's world population.Results: In 2013,the estimated number of new cases and deaths from cervical cancer were 100,700 and 26,400,respectively.The crude incidence of cervical cancer was 15.17/100,000.The age-standardized incidence rates based on the Chinese standard population(ASIRC) and the world standard population(ASIRW) were 11.30/100,000 and10.30/100,000,respectively.The incidence of cervical cancer in urban areas was 15.62/100,000 and the ASIRC was11.12/100,000.The incidence of cervical cancer in rural areas was 14.65/100,000 and the ASIRC was11.47/100,000.The mortality rate of cervical cancer was 3.98/100,000.The age-standardized mortality rates based on the Chinese(ASMRC) and world standard populations(ASMRW) were 2.76/100,000 and 2.62/100,000,respectively.The mortality rate of cervical cancer in urban areas was 3.85/100,000 and in rural areas was4.14/100,000.Cervical cancer incidence and mortality increased with age.Urban areas had a higher incidence of cervical cancer and lower mortality rates when compared with rural areas.Conclusions: Dynamic monitoring of cervical cancer incidence and mortality is the fundamental work of cervical cancer prevention and control.Cervical cancer is a serious issue in women's health,and prevention strategies need to be enhanced,such as human papilloma virus(HPV) vaccination and screening programs. | Bingbing Song Chao Ding Wangyang Chen Huixin Sun Maoxiang Zhang Wanqing Chen | 2017 | Chinese Journal of Cancer Research2017，29，6： | 35 |
| 4 | 蛋鸡J亚群禽白血病病毒的分离与初步鉴定显示文摘 | 冯小宇 徐镔蕊 Lucy F.Lee Maoxiang Li | 2008 | 中国兽医杂志2008，44，1： | 14 |
| 5 | Efficacy of Banxia Xiexin decoction in a rat model of chronic atrophic gastritis显示文摘OBJECTIVE:To investigate the effectiveness of Banxia Xiexin decoction(BXD)in a rat model of chronic atrophic gastritis(CAG).METHODS:Sixty 6-week-old healthy Wistar rats(30 males,30 females)were used in the present study.A rat model of CAG was successfully established using the combined active immunization/ethanol/sodium deoxycholate method.BXD was prepared from a mixture of seven Chinese herbs,and was intragastrically administered to CAG rats at three different doses(6,12,and 24 g·kg^-1·d^-1).Af-ter 24 weeks,the rats were euthanized,and gastric tissue specimens were collected.Gastric mucosal specimens were stained with hematoxylin and eosin for histological examination to evaluate the degree of inflammation and morphological changes.Immunohistochemical staining was performed to examine the mucosal expression of proliferating cell nuclear antigen.Serum gastrin levels were measured using radioimmunoassay.The expression of Notch signaling-associated genes was examined by quantitative polymerase chain reaction and Western blot assay.RESULTS:BXD at all three doses significantly reversed the adverse effects generated by CAG in rats.Compared with control rats,the CAG rats who were administered BXD had an accelerated growth rate,reduced inflammatory cell infiltration,improved gastric mucosal morphology,augmented thickness of the gastric mucosa,increased number of gastric glands,enhanced mucosal expression of proliferating cell nuclear antigen,and elevated serum gastrin levels. | Bai Yu Chen Yongcan Chen Yu Yan Maoxiang Wei Hongquan Wang Hengcang Zeng Guoliang Yang Xiyin | 2019 | Journal of Traditional Chinese Medicine2019，39，6： | 14 |
| 6 | 采用SP法检测商品蛋鸡感染J亚群禽白血病病毒对产蛋性能的影响显示文摘本研究属世界上首次报道J亚群禽白血病病毒感染对蛋鸡产蛋性能的影响。尸体剖检观察到产蛋鸡的生殖系统发育不良,表现为卵巢、输卵管幼稚型,输卵管粗细不均。组织病理学观察,发现卵巢组织中有大量的胞浆内充满球形嗜酸性颗粒的骨髓瘤细胞。用特异性抗J亚群禽白血病病毒(ALV-J)囊膜糖蛋白gp85的单克隆抗体检测不产蛋鸡的卵巢、输卵管等待检的组织切片,均检出病毒阳性抗原。结果表明ALV-J的感染造成产蛋鸡卵巢、输卵管发育不良,是蛋鸡不产蛋的直接原因。 | 徐镔蕊 董卫星 冯小宇 余春明 吕艳丽 孙艳争 李宁 L.F.Lee Maoxiang Li | 2003 | 中国家禽2003，25，6： | 9 |
| 7 | Analysis of cancer incidence and mortality data in Heilongjiang province cancer registries, China, 2015显示文摘Objective In recent years, the rising incidence of cancer has increased patients’ living and economic burdens. This study analyzed the incidence and death due to malignant tumors in tumor registries in Heilongjiang province (China) in 2015 to provide a scientific basis for the prevention and treatment of malignant tumors in this province. Methods Data on tumor incidence and patient deaths were collected from seven tumor registries in Heilongjiang province (China) in 2015. According to the stratification of urban and rural areas and patient sex, the crude, standard, and accumulative rates (0–74 years of age) were calculated. The 2000 China Population Census data and Segi’s standard population were used to calculate the age-standardized rates. Results In 2015, the incidence rate of malignant tumors in Heilongjiang cancer registries was 259.90/100 000. The age-standardized incidence rates in the Chinese and world standard populations were 158.89/100 000 and 155.06/100 000, respectively, with a cumulative incidence rate (0–74 years) of 17.68%. The incidence of malignant tumors in urban areas was 273.55/100 000, while that in rural areas was 220.32/100 000. The incidence of malignant tumors in men was 270.89/100 000, higher than that in women (249.04/100 000). Lung cancer had the highest incidence, followed by breast cancer, liver cancer, colorectal cancer, and thyroid cancer. The mortality rate of malignant tumors in Heilongjiang cancer registries was 164.69/100 000. The age-standardized mortality rates in Chinese and in world standard populations were 95.29/100 000 and 94.35/100 000, respectively, with a cumulative mortality rate (0–74 years) of 10.44%. The mortality rate of malignant tumors in urban areas was 169.51/100 000, while that in rural areas was 150.72/100 000. The mortality rate of malignant tumors in men was 201.64/100 000, higher than that in women (128.21/100 000). Lung cancer had the highest mortality, followed by liver cancer, stomach cancer, colorectal cancer, and breast cancer. Conclusion Lung, liver, breast, and colorectal cancers were the most common cancers in Heilongjiang province, China, and should be considered the key cancer types for prevention and treatment. Moreover, the incidence of thyroid cancer is increasing, and thus early preventative measures should be implemented. | Huixin Sun Bingbing Song Maoxiang Zhang | 2019 | Oncology and Translational Medicine2019，5，4： | 7 |
| 8 | Synthesis and electrochemical performances of spherical LiFePO_4 cathode materials for Li-ion batteries显示文摘Spherical LiFePO4 and LiFePO4/C composite powders for lithium ion batteries were synthesized by a novel processing route of co-precipitation and subsequent calcinations in a nitrogen and hydrogen atmosphere. The precursors of LiFePO4, LiFePO4/C composite and the resultant products were characterized by X-ray diffraction (XRD), scanning electron microscope (SEM), and the electrochemical performances were investigated by galvanostatic charge and discharge tests. The precursors composed of amorphous Fe3(PO4)2·xH2O and crystalline Li3PO4 obtained in the co-precipitation processing have a sphere-like morphology. The spherical LiFePO4 derived from the calcinations of the precursor at 700 ℃ for 10 h in a reduction atmosphere shows a discharge capacity of 119 mAh·g-1 at the C/10 rate, while the LiFePO4/C composite with 10wt.% carbon addition exhibits a discharge capacity of 140 mAh·g-1. The electrochemical performances indicate that the LiFePO4/C composite has a higher specific capacity and a more stable cycling performance than the bare olivine LiFePO4 due to the carbon addition enhancing the electronic conductivity. | ZHOU Jianxin SHEN Xiangqian JING Maoxiang ZHAN Yun | 2006 | Rare Metals2006，25，z1： | 6 |
| 9 | A New Process Industry Fault Diagnosis Algorithm Based on Ensemble Improved Binary-Tree SVM显示文摘Support vector machine(SVM) is an effective tool in deal with small sample, nonlinear and high dimension classification problems. In this paper, an improved pre-treatment binary-tree SVM is proposed to solve fault diagnosis. Furthermore an ensemble method is presented to establish ensemble SVM. Here the improved SVM is used as weak learning machine. The new ensemble SVM can improve the performance of single binary-tree SVM.At the end, the new algorithm is applied to fault diagnosis of blast furnace faults and the Tennessee Eastman process(TEP). The experiments results show that the improved binary-tree SVM algorithm has an excellent performance on diagnosis speed and accuracy. | WANG Anna SHA Mo LIU Limei CHU Maoxiang | 2015 | Chinese Journal of Electronics2015，24，2： | 5 |
| 10 | Liquid modified photonic crystal fiber for simultaneous temperature and strain measurement显示文摘A liquid modified photonic crystal fiber(PCF)integrated with an embedded directional coupler and multi-mode interferometer is fabricated by infiltrating three adjacent air holes of the innermost layer with standard 1.48 refractive index liquids.The refractive index of the filled liquid is higher than that of background silica,which can not only support the transmitting rod modes but also the'liquid modified core'modes propagating between the PCF core and the liquid rods.Hence,the light propagating in the liquid modified core can be efficiently coupled into the satellite waveguides under the phase-matching conditions,resulting in a dramatic decrease of the resonant wavelength intensity.Furthermore,there is a multi-mode interference produced by modified core modes and rod modes.Such a compact(~0.91 cm)device integrated with an embedded coupler and interferometer is demonstrated for high-sensitivity simultaneous temperature(~14.72 nm∕℃)and strain(~13.01 pm∕με)measurement. | CHUPAO LIN YING WANG YIJIAN HUANG CHANGRUI LIAO ZHIYONG BAI MAOXIANG HOU ZHENGYONG LI YIPING WANG | 2017 | Photonics Research2017，5，2： | 3 |
| 11 | 突变型抑癌基因p53在蛋鸡J亚群禽白血病中的表达显示文摘蛋鸡J亚群禽白血病是病毒引起的肿瘤性传染病。为了探讨J亚群禽白血病病毒的致癌分子机理,观察蛋用型鸡发生J亚群禽白血病时p53抑癌基因在各脏器中的表达,应用链霉亲和素-生物素-过氧化物酶复合物免疫组化(SABC)法,研究了蛋用型鸡J亚群禽白血病自然病例的肝脏、肾脏、腺胃、肿瘤、输卵管、心脏、胰脏、骨髓、脾脏、肺脏、十二指肠、胸腺和法氏囊。结果表明:突变型p53在肝脏、肾脏、腺胃、肿瘤、输卵管中表达量最高,心脏、胰脏、骨髓、脾脏、肺脏、十二指肠、胸腺及法氏囊均可检出中等量的表达。这一结果提示突变型抑癌基因p53的表达参与蛋鸡J亚群禽白血病发生、发展过程。 | 徐镔蕊 董卫星 何召庆 余春明 李宁 冯小宇 L.F.Lee Maoxiang Li | 2003 | 农业生物技术学报2003，11，3： | 3 |
| 12 | Repeated exposure to moxa-burning smoke: its acute and chronic toxicities in rats显示文摘OBJECTIVE: To assess toxicities of the air in Chi-nese medicine clinics polluted by moxa-burning smoke due to moxibustion-derived burning products(MBP).METHODS: Both acute and chronic toxicity studies were conducted. For the acute toxicity study, five groups of Wistar rats(n = 16/group, male: female =1∶1) were exposed to five different concentrations(95%, 90%, 85%, 80% and 75%, respectively) of MBP for 2 h. For the chronic toxicity study, another three groups of male rats(n = 21/group) were exposed to MBP in three concentrations(10%, 40%and 70%, respectively) and one control group exposed to clean air 20 min/d for 144 d. Routine examinations were performed and analyzed by analysis of variance and dose-response relationship.RESULTS: In the acute toxicity study, the number of dead rats in the 95%, 90%, 85%, 80% and 75%groups were 16, 13, 7, 6 and 3, respectively, with LD50 of 86.274% after or during the 2 h exposure.In the chronic toxicity study, MBP exposure induced a decline in activity of the rats. Rats in the10% group showed no signs of toxicity, while those in the 40% MBP group showed toxicity effects on the body weights(P < 0.05) and lung. Rats in the70% MBP group also presented with reversible damage in the blood coagulation system(P < 0.05).CONCLUSION: Exposure to 10% MBP, which is equivalent to 27.45 mg/m3, was under the critical threshold for male rats' safety. Exposure to MBP above that limit induced lung damage. MBP in clinics need to be reduced to a safe level with enhanced ventilation. | Han Li Liu Changxi Liu Ping Hu Hai Yang Jia Cai Hong Lim Minyee Zhu Maoxiang Pan Xiujie Huang Jian Cui Yingxue Lao Lixing Zhao Baixiao | 2018 | Journal of Traditional Chinese Medicine2018，38，1： | 3 |
| 13 | Occurrence of avian leukosis virus subgroup J in commercial layer flocks in China显示文摘 | Binrui Xu Weixing Dong Chunming Yu Zhaoqing He Yanli Lv Yanzheng Sun Xiaoyu Feng Ning Li L. F. Lee Maoxiang Li | 2004 | Avian Pathology2004，，1： | 3 |
| 14 | A novel BIST scheme for circuit aging measurement of aerospace chips显示文摘The avionics working environment is bad, easy to accelerate aging of circuits. Circuit aging is one of the important factors that influence the reliability of avionics, so circuit aging testing is of great significance to improve the reliability of avionics. As continuing aging would degrade circuit performance, aging can be monitored through precise measurement of performance degradation. However, previous methods for predicting circuit performance have limited prediction accuracy. In this paper, we propose a novel Built-In Self-Test(BIST) scheme for circuit aging measurement, which constructs self-oscillation loops employing parts of critical paths and activates oscillations by specific test patterns. An aging signature counter is then used to capture the oscillation frequency and in turn measure the aging state of the circuit. We propose to implement this measurement process by BIST. Experimental results show that the proposed in-field aging measurement is robust with respect to process variations and can achieve a precision of about 90%. The application of this scheme has a certain value to improve the reliability of avionics systems. | Huaguo LIANG Xiangsheng FANG Maoxiang YI Zhengfeng HUANG Yingchun LU | 2018 | Chinese Journal of Aeronautics2018，31，7： | 3 |
| 15 | Achieving a sub-10 nm nanopore array in silicon by metal-assisted chemical etching and machine learning显示文摘Solid-state nanopores with controllable pore size and morphology have huge application potential.However,it has been very challenging to process sub-10 nm silicon nanopore arrays with high efficiency and high quality at low cost.In this study,a method combining metal-assisted chemical etching and machine learning is proposed to fabricate sub-10 nm nanopore arrays on silicon wafers with various dopant types and concentrations.Through a SVM algorithm,the relationship between the nanopore structures and the fabrication conditions,including the etching solution,etching time,dopant type,and concentration,was modeled and experimentally verified.Based on this,a processing parameter window for generating regular nanopore arrays on silicon wafers with variable doping types and concentrations was obtained.The proposed machine-learning-assisted etching method will provide a feasible and economical way to process high-quality silicon nanopores,nanostructures,and devices. | Yun Chen Yanhui Chen Junyu Long Dachuang Shi Xin Chen Maoxiang Hou Jian Gao Huilong Liu Yunbo He Bi Fan Ching-Ping Wong Ni Zhao | 2021 | International Journal of Extreme Manufacturing2021，3，3： | 2 |
| 16 | Coating of Fe,Ni on α-alumina microspheres by heterogeneous precilpation 显示文摘 | SHEN Xiangqian LI Donghong JING Maoxiang | 2006 | J Cenlral South Univ Technol2006，13，1： | 1 |
| 17 | Fabrication of Fe, Ni, and FeNi coated Al2O3 core-shell microspheres by the heterogeneous precipitation 显示文摘 | SHEN Xiangqian JING Maoxiang LI Wangxing | 2005 | Powder Technol2005，160，3： | 1 |
| 18 | Transforming growth factor β3 attenuates the development of radiation-induced pulmonary fibrosis in mice by decreasing fibrocyte recruitment and regulating IFN-γ/IL-4 balance显示文摘 | Long Xu Shanshan Xiong Renfeng Guo Zhihua Yang Qianjun Wang Fengjun Xiao Haibao Wang Xiujie Pan Maoxiang Zhu | 2014 | Immunology Letters2014，，1： | 1 |
| 19 | 显示文摘 | Shen Xiangqian Li Donghong Jing Maoxiang | 2006 | J Cent South Univ Thchnol2006，13，1： | 1 |
| 20 | Fabrication of Fe-, Ni- and FeNi-coated Al2O3 core-sheU microspheres by heterogeneous precipitation显示文摘 | SHEN Xiangqian JING Maoxiang LI Wangxing | 2005 | Powder Teehnol2005，160，： | 1 |
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