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| 1 | Loss of interstitial cells of Cajal network in severe idiopathic gastroparesis显示文摘AIM: To report a case of severe idiopathic gastroparesis in complete absence of Kit-positive gastric interstitial cells of Cajal (ICC). METHODS: Gastric tissue from a patient with severe idiopathic gastroparesis unresponsive to medical treatment and requiring surgery was analyzed by conventional histology and immunohistochemistry. RESULTS: Gastric pacemaker cells expressing Kit receptor had completely disappeared while the local level of stem cell factor, the essential ligand for its development and maintenance, was increased. No signs of cell death were observed in the pacemaker region. CONCLUSION: These results are consistent with the hypothesis that a lack of Kit expression may lead to impaired functioning of ICC. Total gastrectomy proves to be curative. | Edda Battaglia Gabrio Bassotti Graziella Bellone Luca Dughera Anna Maria Serra Luigi Chiusa Alessandro Repici Pierroberto Mioli Giorgio Emanuelli | 2006 | World Journal of Gastroenterology2006，12，38： | 20 |
| 2 | A prospective study on radiofrequency ablation locally advanced pancreatic cancer显示文摘BACKGROUND:Radiofrequency ablation(RFA)has been suggested as a new treatment option for patients with locally advanced cancer.This study aimed to prospectively evaluate the efficacy and safety of intraoperative RFA in patients with unresectable,locally advanced,non-metastatic carcinoma of the pancreatic head.METHODS:RFA was the first step of the surgical procedure and was carried out on the mobilized pancreatic head followed by biliary by-pass and gastrojejunal-anastomosis.Intra-and post-operative morbidity and mortality,performance status, pain control,quality of life,and survival at 24 months were evaluated.RESULTS:Seven patients(3 men and 4 women;median age 66 years,range 47-80 years)were studied and 4 were eligible for treatment.The RFA procedure was carried out in 3 of the 4 patients;in one patient it was not carried out because of the upstaging of the neoplasm.In all 3 patients RFA achieved complete necrosis of the lesion.A biliary fistula developed 7 days after the procedure in one patient;all 3 patients developed ascites 8.6 days(range 7-9 days)on average after RFA.All patients died respectively,at 3,4,and 5 months after the treatment.CONCLUSIONS:In our experience,RFA is a feasible procedure, but it presents a very high rate of postoperative complications.Moreover,pain control,life quality and survival rate are poor.The few data suggest no impact on survival. | Riccardo Casadei Claudio Ricci Raffaele Pezzilli Carla Serra Lucia Calculli Antonio Maria Morselli-Labate Donatella Santini Francesco Minni | 2010 | Hepatobiliary & Pancreatic Diseases International2010，9，3： | 6 |
| 3 | Association of chronic hepatitis C with recurrent brief depression显示文摘 | Mauro G. Carta Jules Angst Maria Francesca Moro Gioia Mura Maria Carolina Hardoy Cinzia Balestrieri Luchino Chessa Giancarlo Serra Maria Eliana Lai Patrizia Farci | 2012 | Journal of Affective Disorders2012，，2： | 2 |
| 4 | Optimal synthesis of regeneration systems subject to environmental constraints显示文摘 | Monica Carvalho Luis Maria Serra Miguel Angel | 2011 | Energy2011，36，6： | 1 |
| 5 | Reversible postural tachycardia syndrome due to inadvertent overuse of Red Bull ?显示文摘 | Rossana Terlizzi Camilla Rocchi Maria Serra Laura Solieri Pietro Cortelli | 2008 | Clinical Autonomic Research2008，，4： | 1 |
| 6 | Controllability analysis of decentralised linear controllers for polymeric fuel cells显示文摘 | Maria Serra Joaquin Aguado Xavier Ansede Jordi Riera | 2005 | Journal of Power Sources2005，151，： | 1 |
| 7 | Design and analysis of fuel-cell hybrid systems oriented to automotive applications显示文摘 | Diego Feroldi Maria Serra Jordi Riera | 2009 | IEEE Transactions on Vehicular Technology2009，58，9： | 1 |
| 8 | Prognostic and therapeutic relevance of HER2 expression in osteosarcoma and Ewing’s sarcoma显示文摘 | Katia Scotlandi Maria C. Manara Claudia M. Hattinger Stefania Benini Stefania Perdichizzi Michela Pasello Gaetano Bacci Licciana Zanella Franco Bertoni Piero Picci Massimo Serra | 2005 | European Journal of Cancer2005，，9： | 1 |
| 9 | SARS-CoV-2 productively infects primary human immune system cells in vitro and in CoviD-19 patients显示文摘The severe acute respiratory syndrome coronavirus 2(SARS-CovV-2)infection is associated with a hyperinflammatory state and lymphocytopenia,a hallmark that appears as both signature and prognosis of disease severity outcome.Although cytokine storm and a sustained inflammatory state are commonly associated with immune cell depletion,it is still unclear whether direct SARS-Cov-2 infection of immune cells could also play a role in this scenario by harboring viral replication.We found that monocytes,as well as both B and T lymphocytes,were susceptible to SARS-Cov-2 infection in vitro,accumulating double-stranded RNA consistent with viral RNA replication and ultimately leading to expressive T cell apoptosis.In addition,flow cytometry and immunofluorescence analysis revealed that SARS-Cov-2 was frequently detected in monocytes and B lymphocytes from coronavirus disease 2019(CoVID-19)patients.The rates of SARS-Cov-2-infected monocytes in peripheral blood mononuclear cells from CoVID-19 patients increased over time from symptom onset,with SARS-CoV-2-positive monocytes,B cells,and CD4+T lymphocytes also detected in postmortem lung tissue.These results indicated that SARS-CoV-2 infection of blood-circulating leukocytes in covID-19 patients might have important implications for disease pathogenesis and progression,immune dysfunction,and virus spread within the host. | Marjorie C.Pontelli italo A.Castro Ronaldo B.Martins Leonardo La Serra Flavio P.Veras Daniele C.Nascimento Camila M.Silva Ricardo S.Cardoso Roberta Rosales Rogério Gomes Thais M.Lima Juliano P.Souza Brenda C.Vitti Diego B.Caetite Mikhael H.F.de Lima Spencer D.Stumpf Cassandra E.Thompson Louis-Marie Bloyet Juliana E Toller-Kawahisa Marcela C.Giannini Leticia P.Bonjorno Marial.F.Lopes Sabrina S.Batah Li Siyuan Rodrigo Luppino-Assad Sergio C.L.Almeida Fabiola R.Oliveira Maira N.Benatti Lorena L.F.Pontes Rodrigo C.Santana Fernando C.Vilar Maria Auxiliadora-Martins Pei-Yong Shi Thiago M.Cunha Rodrigo T.Calado JoséC.Alves-Filho Dario S.Zamboni Alexandre T.Fabro Paulo Louzada-Junior Rene D.R.Oliveira Sean P.J.Whelan Fernando Q.Cunha Eurico Arruda | 2022 | Journal of Molecular Cell Biology2022，14，4： | 1 |
| 10 | Immigration Status and HIV-risk Related Behaviors among Female Sex Workers in South America显示文摘 | Christian T. Bautista Carlos Mosquera Margarita Serra Alberto Gianella Maria M. Avila Victor Laguna-Torres Jean K. Carr Silvia M. Montano José L. Sanchez | 2008 | AIDS and Behavior2008，，2： | 1 |
| 11 | Miliary tuberculosis infection during hepatitis C treatment with sofosbuvir and ledipasvir plus ribavirin显示文摘Chronic hepatitis C virus(HCV) infection is one of the main causes of chronic liver disease worldwide. In the last 5 years, treatment for HCV infection has experienced a marked development. In 2014, the use of ledipasvir/sofosbuvir with or without concomitant weight-based ribavirin was approved with a very significant increase in the sustained virological response. However, new side effects have been associated. We report the first case of an HCV infected patient treated for 12 wk with the combination of sofosbuvir/ledipasvir plus ribavirin who developed a miliary tuberculosis(TB) infection while on therapy. The patient was a 65-year-old woman, who referred malaise, asthenia, hyporexia, 7 kg weight loss, productive cough, evening fever and night sweats, right after finishing the treatment. The chest computed tomography-scan revealed a superior mediastinal widening secondary to numerous lymphadenopathies with extensive necrosis and bilateral diffuse lung miliary pattern with little subsequent bilateral pleural effusion, highly suggestive of lymph node tuberculosis with lung miliary spread. A bronchoscopy was performed and bronchial suction showed more than 50 acid-alcohol resistant bacillus per line. A Mycobacterium tuberculosis DNA was detected in blood by polymerase chain reaction, which confirmed the diagnosis of miliary tuberculosis. Some cases of TB infection have been identified with α-interferon-based therapy and with the triple therapy of pegylated interferon, ribavirin and boceprevir or telaprevir. However, significant infection has not been reported with sofosbuvir/ledipasvir plus ribavirin.We believe that the case is relevant to increase awareness of opportunistic infections and particularly TB infection. Although the international guidelines offer no recommendation regarding TB screening, we wonder whether it would be advisable to screen for opportunistic infections prior to the introduction of HCV therapy. | Maria Pilar Ballester-Ferré Fernando Martínez Natalia Garcia-Gimeno Francisco Mora Miguel A Serra | 2017 | World Journal of Hepatology2017，9，3： | 1 |
| 12 | Evaluation of the effects of selected phytochemicals on quorum sensing inhibition and in vitro cytotoxicity显示文摘 | Anabela Borges Sofia Serra Ana Cristina Abreu Maria J. Saavedra António Salgado Manuel Sim?es | 2014 | Biofouling2014，，2： | 1 |
| 13 | Long-Term Study on the Effects of Visual Biofeedback and Muscle Training as a Therapeutic Modality in Pelvic Floor Dyssynergia and Slow-Transit Constipation显示文摘 | Edda Battaglia M.D. Anna Maria Serra M.D. Giuseppina Buonafede M.D. Luca Dughera M.D. Fabio Chistolini M.D. Antonio Morelli M.D. Giorgio Emanuelli M.D. Gabrio Bassotti M.D. Ph.D. F.A.C.G | 2004 | Diseases of the Colon & Rectum2004，，1： | 1 |
| 14 | Three-Dimensional Contrast-Enhanced Ultrasonography of Intraductal Papillary Mucinous Neoplasms of the Pancreas: A Comparison With Magnetic Resonance Imaging显示文摘 | Raffaele Pezzilli Carla Serra Lucia Calculli Fabio Ferroni Maria Teresa Iammarino Riccardo Casadei | 2013 | Pancreas2013，，： | 1 |
| 15 | Association of chronic hepatitis C with recurrent brief depression显示文摘 | Mauro G. Carta Jules Angst Maria Francesca Moro Gioia Mura Maria Carolina Hardoy Cinzia Balestrieri Luchino Chessa Giancarlo Serra Maria Eliana Lai Patrizia Farci | 2012 | Journal of Affective Disorders (-)2012，，2： | 1 |
| 16 | Control and optimization of the divided wall column显示文摘 | Maria Serra Antonio Espuna Luis Puigjaner | 1999 | Chemical Engineering and Processing1999，38，： | 1 |
| 17 | Low-temperature upconversion spectroscopy of nanosized Y203:Er,Yb phosphor显示文摘 | Ana Maria Pires Osvaldo Antonio Serra Stephan Heer | 2005 | J Appl Phys2005，98，06： | 1 |
| 18 | Unchanged plasma levels of dimethylarginines and nitric oxide in chronic hepatitis C显示文摘 | Paloma Lluch Belén Cortina José M. Vila Gloria Segarra Maria D. Mauricio Juan A. Del Olmo Miguel A. Serra Salvador Lluch José M. Rodrigo | 2009 | Scandinavian Journal of Gastroenterology2009，，2： | 1 |
| 19 | Effect of β-adrenergic and renin–angiotensin system blockade on myocyte apoptosis and oxidative stress in diabetic hypertensive rats显示文摘 | Fabio Fiordaliso Noeleen De Angelis Antonio Bai Ivan Cuccovillo Monica Salio Domenico Maria Serra Roberto Bianchi Roberta Razzetti Roberto Latini Serge Masson | 2007 | Life Sciences2007，，12： | 1 |
| 20 | Ultrasound assessment of vascularization of the thickened terminal ileum wall in Crohn’s disease patients using a low-mechanical index real-time scanning technique with a second generation ultrasound contrast agent显示文摘 | Carla Serra Guido Menozzi Antonio Maria Morselli Labate Francesco Giangregorio Paolo Gionchetti Marina Beltrami Daniela Robotti Fabio Fornari Teresa Cammarota | 2006 | European Journal of Radiology2006，，： | 1 |
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