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| 1 | 缺血性卒中的一级预防——美国心脏协会/美国卒中协会卒中委员会指南 动脉粥样硬化性周围血管病跨学科工作组、心血管护理委员会、临床心脏病学委员会、营养、体力活动和代谢委员会以及医疗质量和转归研究跨学科工作组共同倡导显示文摘背景和目的本指南提供有关各种确定和潜在的卒中危险因素证据的概述,并提供降低卒中风险的推荐。方法写作组成员由委员会主席根据每位作者先前在相关课题领域中的工作提名,并经美国心脏协会(AHA)卒中委员会科学声明监督委员会批准。写作组采用系统文献回顾(涵盖时间段为2001年最后一次回顾发表到2005年1月),参考先前已发表的指南、个人文件和专家意见来概括现有的证据,指明现有知识的差距;如果合适,则根据标准的AHA标准做出简明的推荐。写作组全体成员在撰写过程中均有很多机会对推荐进行评论并认可这份声明的最终版本。在AHA科学咨询与协调委员会批准之前,本指南已进行过广泛的同行评议。结果对评价个体首次卒中风险的流程图进行评估。根据干预的可能性(不可干预、可干预或潜在可干预)和证据的强度(证据充分或证据不太充分),对首次卒中的危险因素或风险标记物进行分类。不可干预的危险因素包括年龄、性别、出生体重低、人种/种族和遗传因素。证据充分的可干预危险因素包括高血压、主动或被动吸烟、糖尿病、心房颤动和某些其他心脏病、血脂异常、颈动脉狭窄、镰状细胞病、绝经后激素治疗、不良饮食习惯、缺乏体力活动、肥胖和体脂分布。证据不太充分或潜在的可干预危险因素包括代谢综合征、酗酒、药物滥用、口服避孕药、睡眠呼吸障碍、偏头痛、高同型半胱氨酸血症、脂蛋白(a)升高、脂蛋白相关的磷脂酶升高、高凝状态、炎症和感染。对应用阿司匹林进行卒中一级预防的资料进行回顾。结论有大量证据可以用于确定增加首次卒中风险的各种特殊因素和提供降低这种风险的策略。 | Larry B. Goldstein Robert Adams Mark J. Alberts Lawrence J. Appel Lawrence M. Brass Cheryl D. Bushnell Antonio Culebras Thomas J. DeGraba Philip B. Gorelick John R. Guyton Robert G. Hart George Howard Margaret Kelly-Hayes J.V. (Ian) Nixon Ralph L. Sacco 苏克江 高宗恩 | 2006 | 国际脑血管病杂志2006，14，8： | 28 |
| 2 | 卒中一级预防指南 美国心脏协会/美国卒中协会为医疗卫生专业人员制定的指南美国神经病学学会肯定本指南作为神经科医生继续教育工具的价值显示文摘背景和目的本指南对各种已确定和新出现的卒中危险因素的证据进行概述,以提供降低首次卒中风险的循证推荐。方法写作组成员由委员会主席根据每位成员先前在相关课题领域中的工作提名,并经美国心脏协会(American HeartAssociation,AHA)卒中委员会科学声明监督委员会批准。写作组采用系统文献回顾的方法(涵盖时间为2006年上一次回顾发表到2009年4月),参考先前已发表的指南、个人文件和专家意见来总结现有证据,并指出现有知识的差距;如果合适,则根据标准的AHA标准做出推荐。写作组全体成员均有机会对推荐进行评论并审核这份声明的最终文本。在AHA科学咨询和协调委员会考察和批准之前,本指南已南卒中委员会领导层和AIIA科学声明督察委员会进行过广泛的同行评议。结果对评价个体首次卒巾风险的流程图进行了评价。根据干预的町能性(不可于预、可于预或潜在可干预)和证据的强度(证据充分或证据不太充分),对首次卒中的危险因素或风险标记物进行分类。不可干预危险因素包括年龄、性别、低出生体质量、人种/种族和遗传倾向。证据充分的叮干预危险因素包括高血压、吸烟、糖尿病、心房颤动和某些其他心脏病、血脂异常、颈动脉狭窄、镰状细胞病、绝经后激素治疗、不良饮食习惯、体力活动过少以及肥胖和体脂分布。证据不太充分或潜在的可干预危险因素包括代谢综合征、酗酒、药物滥用、口服避孕药、睡眠呼吸障碍、偏头痛、高同型半胱氨酸血症、脂蛋白(a)升高、高凝状态、炎症和感染。对用阿司匹林进行卒中一级预防的资料进行了回顾。结论多方面的证据可用于确定能增高首次卒中风险的多种具体因素并提供降低这种风险的策略。 | Larry B. Goldstein Cheryl D. Bushnell Robert J. Adams Lawrence J. Appel Lynne T. Braun Seemant Chaturvedi Mark A. Creager Antonio Culebras Robert H. Eckel Robert G. Hart Judith A. Hinchey Virginia J. Howard Edward C. Jauch Steven R. Levine James F. Meschia Wesley S. Moore J.V. (Ian) Nixon Thomas A. Pearson 张霞(译) 尤寿江(译) 陈孝东(译) 卢涛声(译) 石际俊(译) 曹勇军(译) 徐兴顺(译) | 2010 | 国际脑血管病杂志2010，18，12： | 12 |
| 3 | Guidelines for the Primary Prevention of Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association显示文摘 | Larry B. Goldstein Cheryl D. Bushnell Robert J. Adams Lawrence J. Appel Lynne T. Braun Seemant Chaturvedi Mark A. Creager Antonio Culebras Robert H. Eckel Robert G. Hart Judith A. Hinchey Virginia J. Howard Edward C. Jauch Steven R. Levine James F. Meschi | 2011 | Stroke2011，，2： | 6 |
| 4 | Treatment of relapsing autoimmune pancreatitis with immunomodulators and rituximab: the Mayo Clinic experience显示文摘 | Phil A Hart Mark D Topazian Thomas E Witzig Jonathan E Clain Ferga C Gleeson Robin R Klebig Michael J Levy Randall K Pearson Bret T Petersen Thomas C Smyrk Aravind Sugumar Naoki Takahashi Santhi S Vege Suresh T Chari | 2013 | Gut2013，，11： | 2 |
| 5 | Treatment of relapsing autoimmune pancreatitis with immunomodulators and rituximab: the Mayo Clinic experience显示文摘 | Phil A Hart Mark D Topazian Thomas E Witzig Jonathan E Clain Ferga C Gleeson Robin R Klebig Michael J Levy Randall K Pearson Bret T Petersen Thomas C Smyrk Aravind Sugumar Naoki Takahashi Santhi S Vege Suresh T Chari | 2013 | Gut2013，，11： | 2 |
| 6 | Small Firm Growth in the UK Regions 1994- 1997: Towards an Explanatory Framework显示文摘 | Mark Hart Seamus McGuinness | 2003 | Regional Studies2003，37，2： | 1 |
| 7 | A Mutation in the SOS1 Gene Causes Hereditary Gingival Fibromatosis Type 1显示文摘 | Thomas C. Hart Yingze Zhang Michael C. Gorry P. Suzanne Hart Margaret Cooper Mary L. Marazita Jared M. Marks Jose R. Cortelli Debora Pallos | 2002 | The American Journal of Human Genetics2002，，4： | 1 |
| 8 | Nanoscale Patterning of Magnetic Islands by Imprint Lithography Using a Flexible Mold显示文摘 | MCCLELLAND Gary M HART Mark W RETTNE Charles T | 2002 | Applied Physics Letters2002，81，8： | 1 |
| 9 | Total nasal reconstruction: Use of a radial forearm free flap, titanium mesh, and a paramedian forehead flap 显示文摘 | Henry EL Hart RD Mark TS | 2010 | J Otolaryngol Head Neck Surg2010，39，6： | 1 |
| 10 | Vascular Tumors of Bone显示文摘 | Jesse L. Hart Mark A. Edgar Jerad M. Gardner | 2014 | Seminars in Diagnostic Pathology2014，，： | 1 |
| 11 | In vitro biomarker discovery in the parasitic flatworm Fasciola hepatica for monitoring chemotherapeutic treatment显示文摘 | Russell M. Morphew Neil MacKintosh Elizabeth H. Hart Mark Prescott E. James LaCourse Peter M. Brophy | 2014 | EuPA Open Proteomics2014，，： | 1 |
| 12 | The Global Boundary Stratotype Section and Point (GSSP) for the base of the Pliensbachian Stage (Lower Jurassic), Wine Haven, Yorkshire, UK显示文摘 | Christian Meister Martin Aberhan Joachim Blau Jean-Louis Dommergues Susanne Feist-Burkhardt Ernie A. Hailwood Malcom Hart Stephen P. Hesselbos Mark W. Hounslow Mark Hylton Nicol Morton Kevin Page Greg D. Price | 2006 | Episodes2006，29，2： | 1 |
| 13 | Is the Risk of Concomitant Invasive Esophageal Cancer in High-Grade Dysplasia in Barrett’s Esophagus Overestimated?显示文摘 | Vani J.A. Konda Andrew S. Ross Mark K. Ferguson John A. Hart Shang Lin Keith Naylor Amy Noffsinger Mitchell C. Posner Charles Dye Barbara Cislo Lynne Stearns Irving Waxman | 2008 | Clinical Gastroenterology and Hepatology2008，，2： | 1 |
| 14 | Improved statistical methods apphed to surface chemistry in minerals flotation显示文摘 | Brian Hart Mark Biesin4ge Roger St C Smart | 2006 | Minerals Engineering2006，19，68： | 1 |
| 15 | Complete Endoscopic Mucosal Resection Is Effective and Durable Treatment for Barrett’s-Associated Neoplasia显示文摘 | Vani J.A. Konda Mariano Gonzalez Haba Ruiz Ann Koons John Hart Shu–Yuan Xiao Uzma D. Siddiqui Mark K. Ferguson Mitchell Posner Marco G. Patti Irving Waxman | 2014 | Clinical Gastroenterology and Hepatology2014，，： | 1 |
| 16 | Small Firm Growth in the UK Regions 1994-1997: Towards an Explanatory Framework显示文摘 | Mark Hart Seamus McGuinness | 2003 | Regional Studies2003，，2： | 1 |
| 17 | Autocratic leadship in social dilemmas:A threat to group stability显示文摘 | Mark Van Vugt Sarah F Jepson Claire M Hart | 2004 | Journal of Experimental Social Psychology2004，40，： | 1 |
| 18 | Antimicrobial resistance in clinically important biofilms显示文摘A biofilm contains a consortium of cohesive bacterial cells forming a complex structure that is a sedentary, but dynamic, community. Biofilms adhere on biotic and abiotic surfaces, including the surfaces of practically all medical devices. Biofilms are reported to be responsible for approximately 60% of nosocomial infections due to implanted medical devices, such as intravenous catheters, and they also cause other foreign-body infections and chronic infections. The presence of biofilm on a medical device may result in the infection of surrounding tissues and failure of the device, necessitating the removal and replacement ofthe device. Bacteria from biofilms formed on medical devices may be released and disperse, with the potential for the formation of new biofilms in other locations and the development of a systemic infection. Regardless of their location, bacteria in biofilms are tolerant of the activities of the immune system, antimicrobial agents, and antiseptics. Concentrations of antimicrobial agents sufficient to eradicate planktonic cells have no effect on the same microorganism in a biofilm. Depending on the microbial consortium or component of the biofilm that is involved, various combinations of factors have been suggested to explain the recalcitrant nature of biofilms toward killing by antibiotics. In this mini-review, some of the factors contributing to antimicrobial resistance in biofilms are discussed. | Fatemeh Rafii Mark E Hart | 2015 | World Journal of Pharmacology2015，4，1： | 1 |
| 19 | Does Public Accountability Work? An Assessment Tool 显示文摘 | Mark Bovens Thomas Schillemans Hart PT | 2008 | Public Administration2008，86，1： | 1 |
| 20 | Nanoscale Patterning of Magtetic Islands by Imprint Lithography Using a Flexible Mold显示文摘 | Mcclelland Gary M Hart Mark W Retme Charles T | 2002 | Applied Physics Letters2002，81，8： | 1 |
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