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| 1 | 归属、规模、规制:对中国体育学科发展的认识——一种学科方向探究显示文摘当前,中国体育学科的话语地位及学科符号正在不断规范和前行,其中,围绕'学科归属'、'学科规模'、'学科规制'等问题的争论较为集中,理由在于,它们导致了中国体育学科体系分类不明、学位管理的混乱、学问与学说的缺失等问题的出现。然而,学科归属、学科规模及学科规制更应该是一种学科的外在标准,中国的体育学科在规模和规制上已基本形成自己相对独立的体系,问题关键在于学科的'内生'发展。研究认为,中国体育学科的基本方向应在学科内容上从学科分类走向问题关注,研究范式由描述研究走向解释研究,知识建构由联姻嫁接走向内生创新,以更快的实现由'历时态'发展走向'共时态'压缩的历史进程。 | 董德龙 刘文明 SEAMUS Kelly | 2015 | 体育科学2015，35，3： | 45 |
| 2 | Complications in the management of metastatic spinal disease显示文摘Metastatic spine disease accounts for 10% to 30% of new cancer diagnoses annually. The most frequent presentation is axial spinal pain. No treatment has been proven to increase the life expectancy of patients with spinal metastasis. The goals of therapy are pain control and functional preservation. The most important prognostic indicator for spinal metastases is the initial functional score. Treatment is multidisciplinary, and virtually all treatment is palliative. Management is guided by three key issues; neurologic compromise, spinal instability, and individual patient factors. Site-directed radiation, with or without chemotherapy is the most commonly used treatment modality for those patients presenting with spinal pain, causative by tumours which are not impinging on neural elements. Operative intervention has, until recently been advocated for establishing a tissue diagnosis, mechanical stabilization and for reduction of tumor burden but not for a curative approach. It is treatment of choice patients with diseaseadvancement despite radiotherapy and in those with known radiotherapy-resistant tumors. Vertebral resection and ante-rior stabilization with methacrylate or hardware(e.g., cages) has been advocated.Surgical decompression and stabilization, however, along with radiotherapy, may provide the most promising treatment. It stabilizes the metastatic deposited areaand allows ambulation with pain relief. In general, patients who are nonambulatory at diagnosis do poorly, as do patients in whom more than one vertebra is involved. Surgical intervention is indicated in patients with radiation-resistant tumors, spinal instability, spinal compression with bone or disk fragments, progressive neurologic deterioration, previous radiation exposure, and uncertain diagnosis that requires tissue diagnosis. The main goal in the management of spinal metastatic deposits is always palliative rather than curative, with the primary aim being pain relief and improved mobility. This however, does not come without complications, regardless of the surgical intervention technique used. These complication range from the general surgical complications of bleeding, infection, damage to surrounding structures and post operative DT/PE to spinal specific complications of persistent neurologic deficit and paralysis. | Eilis Catherine Dunning Joseph Simon Butler Seamus Morris | 2012 | World Journal of Orthopedics2012，3，8： | 8 |
| 3 | 上海和北京城市创新空间结构的时空演化模式(英文)显示文摘In today's world, the innovation of science and technology has become the key support for improving comprehensive national strength and changing the mode of social production and lifestyle. The country that possesses world-class scientific and technological innovation cities maximizes the attraction of global innovation factors and wins a strategic initiative in international competition. Based on the urban zip code geodatabase, an evaluation system of urban innovation with the perspective of innovation outputs, and the spatial evolutionary mode, concerning the structure of innovation space of Shanghai and Beijing from 1991 to 2014, was developed. The results of the research indicated that the zip code geodatabase provided a new perspective for studying the evolving spatial structure of urban innovation. The resulting evaluation of the spatial structure of urban innovation using the urban zip code geodatabase established by connecting random edge points, was relatively effective. The study illustrates the value of this methodology. During the study period, the spatial structure of innovation of Shanghai and Beijing demonstrated many common features: with the increase in urban space units participating in innovation year by year, the overall gap of regional innovation outputs has narrowed, and the trend towards spatial agglomeration has strengthened. The evolving spatial structure of innovation of Shanghai and Beijing demonstrated differences between the common features during the 25 years as well: in the trend towards the suburbanization of innovation resources, the spatial structure of innovation of Shanghai evolved from a single-core to a multi-core structure. A radiation effect related to traffic arteries as spatial diffusion corridors was prominent. Accordingly, a spatial correlation effect of its innovation outputs also indicated a hollowness in the city center; the spatial structure of innovation of Beijing had a single-core oriented structure all the way. Together with the tendency for innovation resources to be agglomerated in the city center, the spatial correlation effect of innovation outputs reflected the characteristics of the evolutionary feature where 'rural area encircles cities'. The innovation spatial structure of Shanghai and Beijing have intrinsic consistency with the spatial structure of their respective regions(Yangtze River Delta urban agglomeration and Beijing-Tianjin-Hebei metropolitan region), which suggested that the principle of proportional and disproportional distribution of a city-scale pattern of technological and innovational activities is closely related to its regional innovation pattern. | 段德忠 杜德斌 刘承良 Seamus GRIMES | 2016 | Journal of Geographical Sciences2016，26，12： | 6 |
| 4 | Risk factors for Barrett’s oesophagus and oesophageal adenocarcinoma:Results from the FINBAR study显示文摘AIM:To investigate risk factors associated with Barrett's oesophagus and oesophageal adenocarcinoma.METHODS:This all-Ireland population-based case-control study recruited 224 Barrett's oesophagus patients,227 oesophageal adenocarcinoma patients and 260 controls.All participants underwent a structured interview with information obtained about potential lifestyle and environmental risk factors.RESULTS:Gastro-oesophageal reflux was associated with Barrett's [OR 12.0(95% CI 7.64-18.7)] and oesophageal adenocarcinoma [OR 3.48(95% CI 2.25-5.41)].Oesophageal adenocarcinoma patients were more likely than controls to be ex-or current smokers [OR 1.72(95% CI 1.06-2.81)and OR 4.84(95% CI 2.72-8.61)respectively] and to have a high body mass index [OR 2.69(95% CI 1.62-4.46)].No significant associations were observed between these risk factors and Barrett's oesophagus.Fruit but not vegetables were negatively associated with oesophageal adenocarcinoma [OR 0.50(95% CI 0.30-0.86)].CONCLUSION:A high body mass index,a diet low in fruit and cigarette smoking may be involved in the progression from Barrett's oesophagus to oesophageal adenocarcinoma. | Lesley A Anderson RG Peter Watson Seamus J Murphy Brian T Johnston Harry Comber Jim Mc Guigan John V Reynolds Liam J Murray | 2007 | World Journal of Gastroenterology2007，13，10： | 5 |
| 5 | Have patients with esophagitis got an increased risk of adenocarcinoma? Results from a population-based study显示文摘AIM: To examine an increased risk of esophageal adenocarcinoma is restricted to patients who develop Barrett's esophagus or whether esophagitis per se is a risk factor for adenocarcinoma.METHODS: A population-based cohort of patients with histological evidence of esophagitis without Barrett's esophagus was constructed using electronic pathology reports relating to all esophageal biopsies in Northern Ireland between 1993 and 1996. Person-years of followup and incident cases of esophageal cancer were calculated by linking the cohort to death files and the Northern Ireland Cancer Registry records. Standardized incidence ratios (SIR) were calculated for esophageal cancers (adenocarcinoma, squamous cell carcinoma (SCC), and histologically unspecified cancers).RESULTS: A total of 2 013 patients in the cohort provided 13 559 patient-years of follow-up (mean follow-up 6.7 years). None of the patients developed adenocarcinoma. Three patients developed SCC, and six developed histologically unspecified cancers. The SIR for all esophageal cancers and for SCC were 2.73 (95%CI 1.25-5.19) and 2.93 (95%CI 0.61-8.59), respectively. In a sensitivity analysis in which all unspecified esophageal cancers were treated as adenocarcinomas, the SIR for adenocarcinoma was 2.64 (0.97-5.75).CONCLUSION: The risk of adenocarcinoma is not elevated in patients with histological evidence of esophagitis without Barrett's esophagus; however, these patients may have a moderately increased risk of SCC.Further studies are required to confirm these findings,which suggest that Barrett's esophagus, not esophagitis,is the key precursor lesion in the development of adenocarcinoma. | Seamus J Murphy Lesley A Anderson Brian T Johnston Deirdre A Fitzpatrick Peter RG Watson Pauline Monaghan Liam J Murray | 2005 | World Journal of Gastroenterology2005，11，46： | 4 |
| 6 | Mycoplasma pneumoniae infection in a pediatric population: Analysis of soluble immune markers as risk factors for asthma显示文摘 | Jaythoon Hassan Fiona Irwin Seamus Dooley Jeff Connell | 2008 | Human Immunology2008，，12： | 3 |
| 7 | Do medical students studying in the United Kingdom have an adequate factual knowledge of basic life support?显示文摘BACKGROUND: Healthcare professionals have a duty to maintain basic life support(BLS) skills. This study aims to evaluate medical students' factual knowledge of BLS and the training they receive.METHODS: A cross-sectional, closed-response questionnaire was distributed to the fi rst-and fourth-year students studying at institutions in the United Kingdom. The paper questionnaire sought to quantify respondent's previous BLS training, factual knowledge of the BLS algorithm using five multiple choice questions(MCQs), and valuate their desire for further BLS training. Students received 1 point for each correctly identifi ed answer to the 5 MCQ's.RESULTS: A total of 3,732 complete responses were received from 21 medical schools. Eighty percent(n=2,999) of students completed a BLS course as part of their undergraduate medical studies. There was a signifi cant difference(P<0.001) in the percentage of the fourth-year students selecting the correct answer in all the MCQ's compared to the fi rst-year students except in identifyingthe correct depth of compressions required during CPR(P=0.095). Overall 10.3%(95% CI 9.9% to 10.7%) of respondents correctly identified the answer to 5 MCQ's on BLS: 9% of the first-year students(n=194) and 12% of the fourth-year students(n=190). On an institutional level the proportion of students answering all MCQ's correctly ranged from 2% to 54% at different universities. Eighty-one percent of students(n=3,031) wished for more BLS training in their curriculum.CONCLUSION: Factual knowledge of BLS is poor among medical students in the UK. There is a disparity in standards of knowledge across institutions and respondents indicating that they would like more training. | Robert D.Willmore Damjan Veljanoski Feray Ozdes Bethan Stephens James Mooney Seamus G.Crumley Arpan Doshi Philippa Davies Shreya Badhrinarayanan Emily Day Kristian Tattam April Wilson Nathan Crang Lorna Green Craig A.Mounsey Howell Fu Joseph Williams Michelle S.D'souza Dhanya Sebastian Liam A.Mcgiveron Matthew G.Percy James Cohen Imogen J.John Alice Lethbridge Imogen Watkins Omar Amin Mubasher A.Qamar John Gerrard Hanrahan Emily Cramond-Wong | 2019 | World Journal of Emergency Medicine2019，10，2： | 2 |
| 8 | Vacuolating Cytotoxin and Variants in Atg16L1 That Disrupt Autophagy Promote Helicobacter pylori Infection in Humans显示文摘 | Deepa Raju Seamus Hussey Michelle Ang Mauricio R. Terebiznik Michal Sibony Esther Galindo–Mata Vijay Gupta Steven R. Blanke Alberto Delgado Judith Romero–Gallo Mahendra Singh Ramjeet Heidi Mascarenhas Richard M. Peek Pelayo Correa Cathy Streutker Georgina | 2012 | Gastroenterology2012，，5： | 2 |
| 9 | Improving the quality of European hard-cheeses by controlling of interactions between lactic acid bacteria and propionibacteria显示文摘 | Jean-RenéKerjean Seamus Condon Roberta Lodi | 2000 | Food Research International2000，33，： | 1 |
| 10 | Pentazole chemisty:The mechanism of the reaction of aryldiazonium chlorides with azide ion at -80 ℃:Concerted versus stepwise formation of arylpentazoles,detection of a pentazene intermediate,a combined 1H and^15N NMR experimental and ab initio theoretical study显示文摘 | Butler Richard N Fox Anthony Seamus Collier | 1998 | Chem Soc Perkin Trans 21998，，： | 1 |
| 11 | Pentazole chemisty:proton and carbon-^13NMR spectra of some 1-arylpenzaoles:Kinetics and mechanism of degradation of the arylpentazole system显示文摘 | Butler Richard N Collier Seamus Fleming Adrienne F M | 1996 | J Chem Soc Perkin Trans 21996，，： | 1 |
| 12 | Small Firm Growth in the UK Regions 1994- 1997: Towards an Explanatory Framework显示文摘 | Mark Hart Seamus McGuinness | 2003 | Regional Studies2003，37，2： | 1 |
| 13 | Job Security and Labour Market Flexibility 显示文摘 | Seamus Hogan Christopher Ragan | 1995 | Canadian Public Policy1995，12，2： | 1 |
| 14 | Development of a high-speed CNC cutting machine using linear motors显示文摘 | Hillery Michael T | 2005 | Journal of Materials Processing Tech2005，166，3： | 1 |
| 15 | General isospectral flows for linear dynamic systems显示文摘 | Seamus D Garvey Uwe Prells Michael I Friswell Zheng Chert | 2004 | Linear Algebra and its Applications2004，，： | 1 |
| 16 | Efficacy of Adalimumab as a long term maintenance therapy in ulcerative colitis显示文摘 | Edel McDermott Seamus Murphy Denise Keegan Diarmuid O’Donoghue Hugh Mulcahy Glen Doherty | 2012 | Journal of Crohn’s and Colitis2012，，： | 1 |
| 17 | Percutaneous Ultrasound-Guided Thrombin Injection as First-Line Treatment of Pancreatic Pseudoaneurysm显示文摘 | Aoife McErlean Seamus Looby Michael J. Lee | 2007 | CardioVascular and Interventional Radiology2007，，3： | 1 |
| 18 | Repositioning for treat- ing pressure ulcers 显示文摘 | Zena EM Seamus C | 2015 | Cochrane Database Syst Rev2015，1，00： | 1 |
| 19 | Wound cleaning of pressure ulcers 显示文摘 | Zena EM Seamus C | 2011 | Cochrane Database Syst Rev2011，，2： | 1 |
| 20 | Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2 显示文摘 | Colin Adrain Emma MC Seamus JM | 2001 | Embo J2001，20，23： | 1 |
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