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18篇 您的检索式:作者名="Mark Hernandez"
    题名 作者 年代 出处 被引量
1Toxicity of Benzotriazole and Benzotriazole Derivatives to Three Aquatic Species显示文摘David A Pillard Jeffrey S Cornell Doree L DuFresne Mark T Hernandez 2000Water Research2000,,2:2
2Significance of the balance between intracellular glutathione and polyethylene glycol for successful release of small interfering RNA from gold nanoparticles显示文摘为特定的基因 silencing 的小介入 RNA (siRNAs ) 的治疗学的诺言依赖于到细胞质的功能的 siRNAs 的成功的交货。他们到一个确定的交货平台的变化形式例如金 nanoparticles,为治疗疾病并且推进我们细胞的过程的理解提供巨大的潜力。他们的成功或失败依赖于两个进房间和功能的 siRNA 的随后的细胞内部的版本的 nanoparticles 的举起。在这研究,利用金 nanoparticle 对 C-MYC 的 调停siRNA 的交货,我们试图决定我们是否能完成在一个癌症房间击倒与细胞内部的谷胱甘肽的底层排队,并且如果有的话,聚乙烯乙二醇(木钉)决定影响 ligand 密度在上击倒,考虑到决定最佳的 nanoparticle 设计完成 C-MYC 击倒。我们表明那,不管木钉密度,在有相对低的谷胱甘肽层次的房间击倒能被完成,以及为在细胞内部的环境的劈开的 siRNA 的可获得性上的木钉的位的阻碍者的可能的效果。当击倒时,金 nanoparticle 举起经由传播电子显微镜学和集体光谱学被表明被在里面房间 westerns 和 BrdU 加入分别地在蛋白质和生理的层次(在 S 阶段的房间) 决定。Mark McCully Yulan Hernandez Joao Conde Pedro V. Baptista Jesus M. de la Fuente Andrew Hursthouse David Stirling Catherine C. Berry 2015Nano Research2015,8,10:2
3Single droplet drying of detergents:Experimentation and modelling显示文摘This study evaluates the single droplet drying(SDD)of detergents.Experimental data are used to validate a theoretical multistage model.The experiments are carried out in an acoustic levitator analysing six different detergent formulations at 393 K.The work is completed by developing a model based on conservation equations.The model is composed of the three stages observed in the drying curve.In the first stage,an external surface drying stage occurs until the surface is saturated and the crust is formed.In the next stage,the drying rate is governed by diffusion through the pores.At the same time,the particle heats up until boiling conditions are achieved in the core of the particle.At this point,the third stage begins.In the final stage,the droplet core is in boiling conditions which are governed by the pressure drop through the crust and the concentration of salts.This model has been evaluated for the different formulations being flexible to predict the drying of different mixtures with good accuracy.Borja Hernandez Rosa Mondragon Mark A.Pintoa Leonor Hernandez J.Enrique Julia Juan Carlos Jarque Sergio Chiva Mariano Martin 2021Particuology2021,19,5:2
4Presentation and outcome of hepatocellular carcinoma in HIV-infected patients: A U.S.–Canadian multicenter study显示文摘Norbert Br?u Rena K. Fox Peiying Xiao Kristen Marks Zeenat Naqvi Lynn E. Taylor Anita Trikha Morris Sherman Mark S. Sulkowski Douglas T. Dieterich Michael O. Rigsby Teresa L. Wright Maria D. Hernandez Mamta K. Jain Gajendra K. Khatri Richard K. Sterling M 2007Journal of Hepatology2007,,4:1
5Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention显示文摘Leonid Bartik G. Kerr Whitfield Magdalena Kaczmarska Christine L. Lowmiller Eric W. Moffet Julie K. Furmick Zachary Hernandez Carol A. Haussler Mark R. Haussler Peter W. Jurutka 2010The Journal of Nutritional Biochemistry2010,,12:1
6Comparative Treatment of α-Amanitin Poisoning With N -Acetylcysteine, Benzylpenicillin, Cimetidine, Thioctic Acid, and Silybin in a Murine Model显示文摘Tri C. Tong Mark Hernandez William H. Richardson David P. Betten Michael Favata Robert H. Riffenburgh Richard F. Clark David A. Tanen 2007Annals of Emergency Medicine2007,,3:1
7Candidate Gene Polymorphisms for Ischemic Stroke显示文摘Mar Matarin W Mark Brown Hernandez Dena Angela Britton Fabienne Wavrant De Vrieze Thomas G. Brott Robert D. Brown Bradford B. Worrall L Douglas Case Stephen J. Chanock E Jeffrey Metter Luigi Ferruci Dale Gamble John A. Hardy Stephen S. Rich Andrew Singlet 2009Stroke2009,,11:1
8The plasma membrane redox system in aging显示文摘Dong-Hoon Hyun Joe O. Hernandez Mark P. Mattson Rafael de Cabo 2006Ageing Research Reviews2006,,2:1
9Fetal MRI of clubfoot associated with myelomeningocele显示文摘Sabah Servaes Andrea Hernandez Leonardo Gonzalez Teresa Victoria Mark Johnson Diego Jaramillo J. Christopher Edgar Ann Johnson 2010Pediatric Radiology2010,,12:1
10Natural and anthropogenic sources of lead, zinc, and nickel in sediments of Lake Izabal, Guatemala显示文摘Sediments in Lake Izabal,Guatemala,contain substantial lead (Pb),zinc (Zn),and nickel (Ni).The lack of historical data for heavy metal concentrations in the sediments makes it difficult to determine the sources or evaluate whether inputs of metals to the lake have changed through time.We measured the relative abundances and concentrations of Pb,Zn,and Ni by X-Ray Fluorescence core scanning and by Inductively Coupled Plasma Optical Emission Spectrometry in three sediment cores to explore stratigraphic distributions of metals in the lake deposits.High amounts of Pb and Zn in the core taken near the Polochic Delta suggest that galena and sphalerite mining increased Pb and Zn delivery to Lake Izabal between ~1945 and 1965 CE.An up-core Ni increase in the core taken near a different mine on the north shore of Lake Izabal suggests that recent nickel mining operations led to an increase in Ni concentrations in the local sediments,but amounts in the other cores indicate that Ni is not widely distributed throughout the lake.Sediment cores from Lake Izabal are reliable recorders of heavy metal input to the lake,and were measured to establish background metal levels,which would otherwise be unavailable.Concentrations of Pb,Zn,and Ni in older,pre-20th-century Lake Izabal sediments reflect input from natural erosion of bedrock.Our results provide previously unavailable estimates of background metal concentrations in Lake Izabal before the onset of mining.These results are necessary for future monitoring related to mining contamination of the lake ecosystem.Elisandra Hernandez Jonathan Obrist-Farner Mark Brenner William F.Kenney Jason H.Curtis Edward Duarte 2020Journal of Environmental Sciences2020,32,10:1
11The representation of Pa', e{fects using Yield Point Spectra 显示文摘Mark Aschheim Enrique Hernandez Montes 2003Engineering Structures2003,25,11:1
12Incorporating polymerase chain reaction-based identification, population characterization, and quantification of microorganisms into aerosol science: A review显示文摘Jordan Peccia Mark Hernandez 2006Atmospheric Environment2006,,21:1
13In situ assessment of active Thiobacillus species in corroding concrete sewers using fluorescent RNA probes显示文摘Mark Hernandez Eric A Marchand Deborah Roberts 2002International Biodeterioration & Biodegradation2002,49,:1
14The role of NF-kappaB/IkappaB proteins in cancer: implications for novel treatment strategies显示文摘Schwartz SA Hernandez A Mark E B 1999Surg Oncol1999,8,:1
15Polyplex-microbubble hybrids for ultrasound-guided plasmid DNA delivery to solid tumors显示文摘Shashank R. Sirsi Sonia L. Hernandez Lukasz Zielinski Henning Blomback Adel Koubaa Milo Synder Shunichi Homma Jessica J. Kandel Darrell J. Yamashiro Mark A. Borden 2011Journal of Controlled Release2011,,:1
16The role of NFkappaB/IkappaB proteins in cancer: implications for novel treatment strategies 显示文摘Schwartz SA Hernandez A Mark Evers B 1999Surg Oncol1999,8,3:1
17Patterns of antidepressant therapy and clinical outcomes among ischaemic stroke survivors显示文摘Background and purpose Depression is common after stroke and is often treated with antidepressant medications(AD).ADs have also been hypothesised to improve stroke recovery,although recent randomised trials were neutral.We investigated the patterns of in-hospital AD initiation after ischaemic stroke and association with clinical and readmission outcomes.Methods All Medicare fee-for-service beneficiaries aged 65 or older hospitalised for ischaemic stroke in participating Get With The Guidelines-Stroke hospitals between April and December 2014 were eligible for this analysis.Outcome measures included days alive and not in a healthcare institution(home time),all-cause mortality and readmission within 1-year postdischarge.Propensity score(PS)-adjusted logistic regression models were used to evaluate the associations between AD use and each outcome measure.We also compared outcomes in patients prescribed selective serotonin reuptake inhibitors(SSRIs)AD versus those prescribed non-SSRI ADs.Results Of 21805 AD naive patients included in this analysis,1835(8.4%)were started on an AD at discharge.Patients started on an AD had higher rates of depression and prior ischaemic stroke,presented with higher admission National Institutes of Health Stroke Scale score and were less likely to be discharged home.Similarly,patients started on an SSRI had lower rates of discharge to home.Adjusting for stroke severity,patients started on an AD had worse all-cause mortality,all-cause readmission,major adverse cardiac events,readmission for depression and decreased home-time.However,AD use was also associated with an increased risk for the sepsis,a falsification endpoint,suggesting the presence of residual confounding.Conclusions Patients with ischaemic stroke initiated on AD therapy are at increased risk of poor clinical outcomes and readmission even after PS adjustment,suggesting that poststroke depression requiring medication is a poor prognostic sign.Further research is needed to explore the reasons why depression is associated with worse outcome,and whether AD treatment modifies this risk or not.Mark R Etherton Shreyansh Shah Xu Haolin Ying Xian Lesley Maisch Deidre Hannah Brianna Lindholm Barbara Lytle Laine Thomas Eric E Smith Gregg C Fonarow Lee H Schwamm Deepak L Bhatt Adrian F Hernandez Emily C O'Brien 2021Stroke & Vascular Neurology2021,6,3:0
18温哥华公寓显示文摘温哥华公寓的建成预示着这个年轻的城市正在打开城市政策制定的新局面。它将成为从Granville大桥进入温哥华市中心的城市大门。塔楼和群房的设计是对新城市主义地域类型中的'温哥华主义'建筑的全新解读,配合一座纤细的塔楼,试图保留城市视觉通廊并激活步行通道。住宅塔楼借助高度和毗邻河流的地理位置,是唯一可以同时享受水景和山景的建筑,坐拥温哥华广袤的自然风光。Carl McDonald Melissa Bauld Aaron Mark Alan Tansey Alex Wu Alexandra Gustafsson Alina Tamosiunaite Amina Blacksher Aran Coakley Arash Adel Ahmadian Armen Menendian Barbora Srpkova Ben Zunkeler Benjamin Caldwell Benjamin Novacinski Bennett Gale Birk Daugaard Blake Theodore Smith Brian Foster Brian Rome Carolien Schippers Christopher James Malcolm Jr. Christopher Junkin Christopher Tron David Brown David Dottelonde Deborah Campbell Doug Stechschulte Douglass Alligood Edward Yung Elena Bresciani Filip Milovanovic Francesca Portesine Gabriel Hernandez Solano Gabriel Jewell-Vitale Hector Garcia Ivy Hume Jan Leenknegt Janice Rim John Kim Josiah Poland Julian Liang Julianne Gola Julie Kaufman Karol Bogdan Borkowski Kurt Nieminen Lauren Turner Lorenz Krisai Lucio Santos Marcella Martinez Martin Voelkle Matthew Dlugosz Megan Ng Michael Robert Taylor Otilia Pupezeanu Paula Domka Phillip MacDougall Ryan Yang Sean Franklin Sebastian Grogaard Simon Scheller Spencer Hayden Taylor Fulton Terrence Chew Terry Lallak Thomas Smith Tianqi Zhang Tobias Hjortdal Tran Le Valentina Mele Xinyu Wang Yaziel Juarbe Yoanna Shivarova Zach Walters Zhifei Xu Andrew Latreille Glotman Simpson Urban YVR 运小红(译) 2019城市环境设计2019,0,2:0
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