|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Helicobacter pylori-related chronic gastritis as a risk factor for colonic neoplasms显示文摘To summarize the current views and insights on associations between Helicobacter pylori(H. pylori)-related chronic gastritis and colorectal neoplasm, we reviewed recent studies to clarify whether H. pylori infection/H. pylori-related chronic gastritis is associated with an elevated risk of colorectal neoplasm. Recent studies based on large databases with careful control for confounding variables have clearly demonstrated an increased risk of colorectal neoplasm associated with H. pylori infection. The correlation between H. pylori-related chronic atrophic gastritis(CAG) and colorectal neoplasm has only been examined in a limited number of studies. A recent large study using a national histopathological database, and our study based on the stage of H. pylori-related chronic gastritis as determined by serum levels of H. pylori antibody titer and pepsinogen, indicatedthat H. pylori-related CAG confers an increased risk of colorectal neoplasm, and more extensive atrophic gastritis will probably be associated with even higher risk of neoplasm. In addition, our study suggested that the activity of H. pylori-related chronic gastritis is correlated with colorectal neoplasm risk. H. pylori-related chronic gastritis could be involved in an increased risk of colorectal neoplasm that appears to be enhanced by the progression of gastric atrophy and the presence of active inflammation. | Izumi Inoue Jun Kato Hideyuki Tamai Mikitaka Iguchi Takao Maekita Noriko Yoshimura Masao Ichinose | 2014 | World Journal of Gastroenterology2014，20，6： | 25 |
| 2 | Stratifying the risk of lymph node metastasis in undifferentiated-type early gastric cancer显示文摘AIM:To study how lymph node metastasis(LNM) risk is stratified in undifferentiated-type early gastric cancer(undiff-EGC) dependent on combinations of risk factors.METHODS:Five hundred and sixty-seven cases with undiff-EGC undergoing gastrectomy with lymphadenectomy were examined retrospectively.Using clinicopathological factors of patient age,location,size,an endoscopic macroscopic tumor form,ulceration,depth,histology,lymphatic involvement(LI) and venous involvement(VI),LNM risk was examined and stratified by conventional statistical analysis and datamining analysis.RESULTS:LNM was positive in 44 of 567 cases(7.8%).Univariate analysis revealed > 2 cm,protrusion,submucosal(sm),mixed type,LI and VI as significant prognostic factors and > 2 cm and LI-positive were independent factors by multivariate analysis.In preoperatively evaluable factors excluding LVI,sm and > 2 cm were independent factors.According to the depth and size,cases were categorized into the low-risk group [m and ≤ 2 cm,0%(LNM incidence)],the moderaterisk group(m and > 2 cm,5.6%; and sm and ≤ 2 cm,6.0%),and the high-risk group(sm and > 2 cm,19.3%).On the other hand,LNM occurred in 1.4% in all LI-negative cases,greatly lower than 28.2% in all LI-positive cases,and LNM incidence was low in LInegative cases even in the moderate- and high-risk groups.CONCLUSION:LNM-related factors in undiff-EGC were depth and size preoperatively while those were LI and size postoperatively.Among these factors,LI was the most significantly correlated factor. | Yukiko Asakawa Masahiko Ohtaka Shinya Maekawa Mitsuharu Fukasawa Yasuhiro Nakayama Tatsuya Yamaguchi Taisuke Inoue Tomoyoshi Uetake Minoru Sakamoto Tadashi Sato Yoshihiko Kawaguchi Hideki Fujii Kunio Mochizuki Masao Hada Toshio Oyama Tomotaka Yasumura Kosaku Omata Atsushi Nishiyama Keiichi Naito Hideo Hata Yoshiaki Haba Kazuyuki Miyata Haruhisa Saitoh Yoichi Yamadera Kazuo Miura Akira Kawaoi Tohru Abe Hajime Tsunoda Yuji Honda Masayuki Kurosaki Nobuyuki Enomoto | 2015 | World Journal of Gastroenterology2015，21，9： | 8 |
| 3 | Effects of age on survival and morbidity in gastric cancer patients undergoing gastrectomy显示文摘AIM To evaluate clinicopathological features and surgical outcomes of gastric cancer in elderly and non-elderly patients after inverse probability of treatment weighting(IPTW) method using propensity score.METHODS We enrolled a total of 448 patients with histologically confirmed primary gastric carcinoma who received gastrectomies. Of these, 115 patients were aged > 80 years old(Group A), and 333 patients were aged < 79 years old(Group B). We compared the surgical outcomes and survival of the two groups after IPTW.RESULTS Postoperative complications, especially respiratory complications and hospital deaths, were significantly more common in Group A than in Group B(P < 0.05). Overall survival(OS) was significantly lower in Group A patients than in Group B patients. Among the subset of patients who had pathological Stage Ⅰ?disease, OS was significantly lower in Group A(P < 0.05) than Group B, whereas cause-specific survival was almost equal in the two groups. In multivariate analysis, pathological stage, histology, and extent of lymph node dissection wereindependent prognostic values for OS.CONCLUSION When the gastrectomy was performed in gastric cancer patients, we should recognized high mortality and comorbidities in that of elderly. More extensive lymph node dissection might improve prognoses of elderly gastric cancer patients. | Yoshinori Fujiwara Shuichi Fukuda Masanori Tsujie Hajime Ishikawa Kotaro Kitani Keisuke Inoue Masao Yukawa Masatoshi Inoue | 2017 | World Journal of Gastrointestinal Oncology2017，9，6： | 4 |
| 4 | Altered mucosal DNA methylation in parallel with highly active Helicobacter pylori -related gastritis显示文摘 | Takeichi Yoshida Jun Kato Takao Maekita Satoshi Yamashita Shotaro Enomoto Takayuki Ando Tohru Niwa Hisanobu Deguchi Kazuki Ueda Izumi Inoue Mikitaka Iguchi Hideyuki Tamai Toshikazu Ushijima Masao Ichinose | 2013 | Gastric Cancer2013，，4： | 3 |
| 5 | A large impact of tropical biomass burning on CO and CO_2 in the upper troposphere显示文摘A large interannual variation of biomass burning emissions from Southeast Asia is associated with the ENSO events. During 1997/98 and 1994 El Nino years, uncontrolled wildfires of tropical rainforests and peat lands in Indonesia were enlarged due to a long drought. Enhanced CO injection into the upper troposphere from the intense Indonesian fires was clearly observed in the 8-year measurements from a regular flask sampling over the western Pacific using a JAL airliner between Australia and Japan. This airliner observation also revealed that upper tropospheric CO2 cycle largely changed during the 1997 El Nino year due partly to the biomass burning emissions. Widespread pollution from the biomass burnings in Southeast Asia was simulated using a CO tracer driven by a 3D global chemical transport model. This simulation indicates that tropical deep convections connected to rapid advection by the subtropical jet play a significant role in dispersing biomass-burning emissions from Southeast Asia on a global scale. | Hidekazu Matsueda Shoichi Taguchi Hisayuki Y. Inoue Masao Ishii | 2002 | Science China(Life Sciences)2002，45，z1： | 2 |
| 6 | Induction of ischemic tolerance in rat liver via reduced nicotinamide adenine dinucleotide phosphate oxidase in Kupffer cells显示文摘AIM: To elucidate the mechanisms of hepatocyte preconditioning by H2O2 to better understand the pathophysiology of ischemic preconditioning. METHODS: The in vitro effect of H2O2 pretreatment was investigated in rat isolated hepatocytes subjected to anoxia/reoxygenation. Cell viability was assessed with propidium iodide fluorometry. In other experiments, rat livers were excised and subjected to warm ischemia/ reperfusion in an isolated perfused liver system to determine leakage of liver enzymes. Preconditioning was performed by H2O2 perfusion, or by stopping the perfusion for 10 min followed by 10 min of reperfusion. To inhibit Kupffer cell function or reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, gadolinium chloride was injected prior to liver excision, or diphenyleneiodonium, an inhibitor of NADPH oxidase, was added to the perfusate, respectively. Histological detection of oxygen radical formation in Kupffer cells was performed by perfusion with nitro blue tetrazolium. RESULTS: Anoxia/reoxygenation decreased hepatocyte viability compared to the controls. Pretreatment with H2O2 did not improve such hepatocyte injury. In liver perfusion experiments, however, H2O2 preconditioning reduced warm ischemia/reperfusion injury, which wasreversed by inhibition of Kupffer cell function or NADPH oxidase. Histological examination revealed that H2O2 preconditioning induced oxygen radical formation in Kupffer cells. NADPH oxidase inhibition also reversed hepatoprotection by ischemic preconditioning. CONCLUSION: H2O2 preconditioning protects hepato- cytes against warm ischemia/reperfusion injury via NADPH oxidase in Kupffer cells, and not directly. NADPH oxidase also mediates hepatoprotection by ischemic preconditioning. | Kazuaki Tejima Masahiro Arai Hitoshi Ikeda Tomoaki Tomiya Mikio Yanase Yukiko Inoue Takako Nishikawa Naoko Watanabe Natsuko Ohtomo Masao Omata Kenji Fujiwara | 2007 | World Journal of Gastroenterology2007，13，38： | 2 |
| 7 | A case of chronic pancreatitis in which endoscopic ultrasonography was effective in the diagnosis of a pseudoaneurysm显示文摘Endoscopic ultrasonography (EUS) was performed on a patient being treated for chronic pancreatitis because a submucosal tumor was observed in the stomach during gastrointestinal endoscopy. As internal pulsa- tile blood flow on Doppler was present, the diagnosis of an aneurysm was made. The pseudoaneurysm of the left gastric artery was embolized with histoacryl and lipiodol and the splenic artery was embolized with coils at the location of the pseudoaneurysm to prevent hemorrhage. Follow up EUS confirmed the cessation of blood flow from the pseudoaneurysm. Clinicians encountering a gastric submucosal tumor-like protrusion in a patient with chronic pancreatitis should use EUS to investigate the possibility of a pseudoaneurysm, which must be treated as quickly as possible once identified. | Kazuhiro Fukatsu Kazuki Ueda Hiroki Maeda Yasunobu Yamashita Masahiro Itonaga Yoshiyuki Mori Kosaku Moribata Naoki Shingaki Hisanobu Deguchi Shotaro Enomoto Izumi Inoue Takao Maekita Mikitaka Iguchi Hideyuki Tamai Jun Kato Masao Ichinose | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，7： | 2 |
| 8 | Elevated risk of recurrent colorectal neoplasia with Helicobacter pylori?associatedchronic atrophic gastritis: A follow?up study of patients with endoscopicallyresected colorectal neoplasia显示文摘 | Izumi Inoue Jun Kato Noriko Yoshimura Yoshimasa Maeda Kosaku Moribata Naoki Shingaki Hisanobu Deguchi Shotaro Enomoto Takao Maekita Kazuki Ueda Mikitaka Iguchi Hideyuki Tamai Mitsuhiro Fujishiro Nobutake Yamamichi Tatsuya Takeshita Masao Ichinose | 2013 | Molecular and Clinical Oncology2013，，1： | 1 |
| 9 | Incidence and characteristics of uterine leiomyomas with FDG uptake显示文摘 | Sadahiko Nishizawa Masayuki Inubushi Aki Kido Masao Miyagawa Takeshi Inoue Katsura Shinohara Makoto Kajihara | 2008 | Annals of Nuclear Medicine2008，，9： | 1 |
| 10 | Effect of wave height and sea water level on wave overtopping and wave run-up显示文摘 | Yuichi Iwagaki Akira Shima Masao Inoue | 1965 | JSCE1965，8，： | 1 |
| 11 | Tranilast Prevents Atrial Remodeling and Development of Atrial Fibrillation in a Canine Model of Atrial Tachycardia and Left Ventricular Dysfunction显示文摘 | Yosuke Nakatani Kunihiro Nishida Masao Sakabe Naoya Kataoka Tamotsu Sakamoto Yoshiaki Yamaguchi Jotaro Iwamoto Koichi Mizumaki Akira Fujiki Hiroshi Inoue | 2013 | Journal of the American College of Cardiology2013，，： | 1 |
| 12 | Present and Future Trends of Stainless Steel for Automotive Exhaust System 显示文摘 | Yoshiharu INOUE Masao KIKUCHI | 2003 | Nippon Steel Technical Report2003，88，： | 1 |
| 13 | Greater expression of inflammatory cytokines, adrenomedullin, and natriuretic peptide receptor-C in epicardial adipose tissue in coronary artery disease显示文摘 | Ikuko Shibasaki Toshio Nishikimi Yoshihiko Mochizuki Yasuyuki Yamada Masao Yoshitatsu Yuho Inoue Toshiyuki Kuwata Hironaga Ogawa Go Tsuchiya Toshihiko Ishimitsu Hirotsugu Fukuda | 2010 | Regulatory Peptides2010，，2： | 1 |
| 14 | An experimental study of casing performance under thermal cycling condition显示文摘 | Kazush Maruyam Masao Ogasawara Yasusuke Inoue | 1990 | SPE drilling engineering1990，，16： | 1 |
| 15 | Autofluorescence imaging with a transparent hood for detection of colorectal neoplasms: a prospective, randomized trial显示文摘 | Yoji Takeuchi Takuya Inoue Noboru Hanaoka Koji Higashino Hiroyasu Iishi Rika Chatani Masao Hanafusa Takashi Kizu Ryu Ishihara Masaharu Tatsuta Toshio Shimokawa Noriya Uedo | 2010 | Gastrointestinal Endoscopy2010，，5： | 1 |
| 16 | Expression profiling of estrogen-responsive genes in breast cancer cells treated with alkylphenols, chlorinated phenols, parabens, or bis- and benzoylphenols for evaluation of estrogenic activity显示文摘 | Shunichi Terasaka Akio Inoue Masao Tanji Ryoiti Kiyama | 2005 | Toxicology Letters2005，，2： | 1 |
| 17 | A transcutaneous energy transmission system for an artificial organ by using a novel resonant converter显示文摘 | Takeshi Inoue Toshi Hiro Nishimura Masao Saito Musuo Nakaoka | 1992 | IEEE Transactions on Power Electronics1992，7，2： | 1 |
| 18 | Oral administration of royal jelly inhibits the development of atopic dermatitis-like skin lesions in NC/Nga mice显示文摘 | Yoshifumi Taniguchi Keizo Kohno Shin-ichiro Inoue Satomi Koya-Miyata Iwao Okamoto Norie Arai Kanso Iwaki Masao Ikeda Masashi Kurimoto | 2003 | International Immunopharmacology2003，，9： | 1 |
| 19 | Factors associated with a poor response to gefitinib in the NEJ002 study: Smoking and the L858R mutation显示文摘 | Tatsuro Fukuhara Makoto Maemondo Akira Inoue Kunihiko Kobayashi Shunichi Sugawara Satoshi Oizumi Hiroshi Isobe Akihiko Gemma Masao Harada Hirohisa Yoshizawa Ichiro Kinoshita Yuka Fujita Yasuo Saijo Koichi Hagiwara Satoshi Morita Toshihiro Nukiwa | 2015 | Lung Cancer2015，，： | 1 |
| 20 | Japanese apricot improves symptoms of gastrointestinal dysmotility associated with gastroesophageal reflux disease显示文摘AIM: To investigate the effects of Japanese apricot(JA) consumption on gastroesophageal reflux disease(GERD)-related symptoms.METHODS: Participants included individuals living in Minabe-cho,a well-known JA-growing region,who received specific medical check-ups by the local community health service in 2010.GERD-related symptoms were examined in 1303 Japanese individuals using a validated questionnaire,the Frequency Scale for Symptoms of GERD(FSSG),which consists of 7 questions associated with acid reflux symptoms and 5 questions asking about gastrointestinal dysmotility symptoms.Each question was answered using a 4-point scale,with higher scores indicating more severe GERDrelated symptoms.Subjects were divided into two groups according to their intake of dried and pickled JA: daily intake(≥ 1 JA daily)(392 subjects) and none oroccasional intake(< 1 JA daily)(911 subjects).FSSG scores were compared between subjects who consumed JA daily and those who did not.Next,subjects were stratified by age,gender and Helicobacter pylori(H.pylori) status for subanalyses.RESULTS: Those who ate JA daily were significantly older than those who did not(60.6 ± 10.5 years vs 56.0 ± 11.0 years,P < 0.001).Total FSSG scores were significantly lower in subjects with daily JA intake than in those with none or only occasional intake(2.13 ± 3.14 vs 2.70 ± 3.82,P = 0.005).In particular,subjects who consumed JA daily showed significantly improved FSSG dysmotility scores compared with subjects who did not(1.05 ± 1.58 vs 1.46 ± 2.11,P < 0.001).In contrast,the FSSG reflux score did not differ between subjects with and without daily intake of JA(1.08 ± 1.90 vs 1.24 ± 2.11,P = 0.177).Subanalysis indicated that improvement in dysmotility by JA intake was specifically observed in non-elderly(1.24 ± 1.68 vs 1.62 ± 2.22,P = 0.005) and H.pylori-negative subjects(0.99 ± 1.58 vs 1.57 ± 2.06,P < 0.001).GERD patients(total FSSG score ≥ 8) were less frequently observed among subjects with daily intake of JA as compared to those without daily intake of JA(6.1% vs 9.7%,P = 0.040).CONCLUSION: Daily JA intake may improve digestive dysmotility symptoms,resulting in relief of GERD symptoms.The effect is more obvious in non-elderly and H.pylori-negative subjects. | Takao Maekita Jun Kato Shotaro Enomoto Takeichi Yoshida Hirotoshi Utsunomiya Hideyuki Hayashi Toshiko Hanamitsu Izumi Inoue Yoshimasa Maeda Kosaku Moribata Yosuke Muraki Naoki Shingaki Hisanobu Deguchi Kazuki Ueda Mikitaka Iguchi Hideyuki Tamai Masao Ichinose | 2015 | World Journal of Gastroenterology2015，21，26： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员