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| 1 | Biodegradable Zn–3Cu and Zn–3Cu–0.2Ti alloys with ultrahigh ductility and antibacterial ability for orthopedic applications显示文摘Zinc(Zn) and its alloys have been proposed as biodegradable implant materials due to their unique combination of biodegradability, biocompatibility, and biofunctionality. However, the insufficient mechanical properties of pure Zn greatly limit its clinical application. Here, we report on the microstructure, mechanical properties, friction and wear behavior, corrosion and degradation properties, hemocompatibility, and cytocompatibility of Zn–3 Cu and Zn–3 Cu–0.2 Ti alloys under three different conditions of as-cast(AC),hot-rolling(HR), and hot-rolling plus cold-rolling(HR + CR). The HR + CR Zn–3 Cu–0.2 Ti exhibited the best set of comprehensive properties among all the alloy samples, with yield strength of 211.0 MPa, ultimate strength of 271.1 MPa, and elongation of 72.1 %. Immersion tests of the Zn–3 Cu and Zn–3 Cu–0.2 Ti alloys in Hanks’ solution for 3 months indicated that the AC samples showed the lowest degradation rate,followed by the HR samples, and then the HR + CR samples, while the HR + CR Zn–3 Cu exhibited the highest degradation rate of 23.9 m/a. Friction and wear testing of the Zn–3 Cu and Zn–3 Cu–0.2 Ti alloys in Hanks’ solution indicated that the AC samples showed the highest wear resistance, followed by the HR samples, and then the HR + CR samples, while the AC Zn–3 Cu–0.2 Ti showed the highest wear resistance.The diluted extracts of HR + CR Zn–3 Cu and Zn–3 Cu–0.2 Ti at a concentration of ≤25 % exhibited noncytotoxicity. Furthermore, both the HR + CR Zn–3 Cu and Zn–3 Cu–0.2 Ti exhibited effective antibacterial properties against S. aureus. | Jixing Lin Xian Tong Kun Wang Zimu Shi Yuncang Li Matthew Dargusch Cuie Wen | 2021 | Journal of Materials Science & Technology2021，，9： | 3 |
| 2 | Consensus Guidelines for the Management of Postoperative Nausea and Vomiting显示文摘 | Tong J. Gan Pierre Diemunsch Ashraf S. Habib Anthony Kovac Peter Kranke Tricia A. Meyer Mehernoor Watcha Frances Chung Shane Angus Christian C. Apfel Sergio D. Bergese Keith A. Candiotti Matthew TV Chan Peter J. Davis Vallire D. Hooper Sandhya Lagoo-Deena | 2014 | Anesthesia & Analgesia2014，，： | 2 |
| 3 | A novel 3-dimensional micro-ultrasound approach to automated measurement of carotid arterial plaque volume as a biomarker for experimental atherosclerosis显示文摘 | Matthew Walker Barry R. Campbell Karim Azer Christopher Tong Kaijie Fang Jacquelynn J. Cook Michael J. Forrest Kimberly Kempadoo Samuel D. Wright Jeffrey S. Saltzman Euan MacIntyre Richard Hargreaves | 2009 | Atherosclerosis2009，，1： | 1 |
| 4 | Single dose tropistetron for preventing postoperative nausea and vomiting after breast swrgery显示文摘 | Matthew T V Po Tong C Wai S H | 1998 | Anesth Analg1998，87，： | 1 |
| 5 | Single dose tropistetton fo preventing postop erative nausea and vomiting after breast swrgery显示文摘 | Matthew TV Po TONG C Wai SH | 1998 | Anesth Analg1998，87，： | 1 |
| 6 | Use of Allopurinol in Slowing the Progression of Renal Disease Through Its Ability to Lower Serum Uric Acid Level显示文摘 | Yui-Pong Siu Kay-Tai Leung Matthew Ka-Hang Tong Tze-Hoi Kwan | 2005 | American Journal of Kidney Diseases2005，，1： | 1 |
| 7 | The Financial Market Impact of Quantitative Easing in the United Kingdom显示文摘 | Joyce Michael Ana Lasaosa Ibrahim Stevens Matthew Tong | 2011 | International Journal of Central Banking2011，，7： | 1 |
| 8 | QE and the Gilt Market: a Disaggregated Analysis*显示文摘 | Michael A.S. Joyce Matthew Tong | 2012 | The Economic Journal . 2012 (564)2012，，564： | 1 |
| 9 | Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells显示文摘 | Tong Ihn Lee Richard G. Jenner Laurie A. Boyer Matthew G. Guenther Stuart S. Levine Roshan M. Kumar Brett Chevalier Sarah E. Johnstone Megan F. Cole Kyo-ichi Isono Haruhiko Koseki Takuya Fuchikami Kuniya Abe Heather L. Murray Jacob P. Zucker Bingbing Yuan | 2006 | Cell2006，，2： | 1 |
| 10 | Immunophenotyping identifies distinct cellular signatures for systemic lupus erythematosus and lupus nephritis显示文摘Background:Systemic lupus erythematosus(SLE)is a complex systemic autoimmune disease characterized by development of autoantibodies and multiorgan involvement.Kidney involvement,termed lupus nephritis,has major impact on life expectancy.It is increasingly recognized that SLE is likely a common clinical manifestation of pathophysiologically diverse processes,and lupus nephritis has similarly been associated with several distinct immunological processes.We compared the immune cell phenotypes of individuals with SLE in the presence or absence of nephritis.Methods:Cryopreserved peripheral blood mononuclear cells from SLE patients with and without kidney involvement underwent flow cytometric analysis to identify major populations in T cells,B cells and myeloid lineages.Results:We compared the frequencies of lymphocyte populations in 69 SLE patients without nephritis,20 SLE patients with nephritis,and 92 healthy blood donors.Patients with SLE and lupus nephritis(LN)had reduced marginal zone B cells(P<0.0001 in SLE;P=0.001 in LN),memory B cells(P=0.002 in SLE;P=0.001 in LN)and circulating T follicular helper(Tfh)memory cells(P<0.0001 in SLE and LN)compared to healthy donors.Patients with lupus nephritis had increase Th2(P<0.0001)and T regulatory cells(P<0.0001)compared to both SLE patients without nephritis and healthy donors.Conclusion:SLE patients with and without lupus nephritis have distinct immunologic differences that may reflect the unique pathophysiological processes contributing to disease manifestations. | Yi Tong V.Aw Phillip J.Whiley Ayla May Lorenzo Tom Lea-Henry Somasundhari Shanmuganandam Maurice Stanley Sonia N.Babu Vicki Athanasopoulos Jean Cappello Julia I.Ellyard Matthew Cook Carola Vinuesa Giles Walters David A.Fulcher Simon H.Jiang | 2023 | Rheumatology & Autoimmunity2023，3，1： | 0 |
| 11 | Elusive liver factor that causes pancreatic α cell hyperplasia: A review of literature显示文摘Tumors and cancers of the gastrointestinal tract and pancreas are commonly derived from precursor lesions so that understanding the physiological, cellular, and molecular mechanisms underlying the pathogenesis of precursor lesions is critical for the prevention and treatment of those neoplasms. Pancreatic neuroendocrine tumors(PNETs) can also be derived from precursor lesions. Pancreatic α cell hyperplasia(ACH), a specific and overwhelming increase in the number of α cells, is a precursor lesion leading to PNET pathogenesis. One of the 3 subtypes of ACH, reactive ACH is caused by glucagon signaling disruption and invariably evolves into PNETs. In this article, the existing work on the mechanisms underlying reactive ACH pathogenesis is reviewed. It is clear that the liver secretes a humoral factor regulating α cell numbers but the identity of the liver factor remains elusive. Potential approaches to identify the liver factor are discussed. | Run Yu Yun Zheng Matthew B Lucas Yun-Guang Tong | 2015 | World Journal of Gastrointestinal Pathophysiology2015，6，4： | 0 |
| 12 | Binary Zn–Ti alloys for orthopedic applications:Corrosion and degradation behaviors,friction and wear performance,and cytotoxicity显示文摘Zinc(Zn)and its biocompatible and biodegradable alloys have substantial potential for use in orthopedic implants.Nevertheless,pure Zn with a hexagonal close-packed crystal structure has only two independent slip systems,therefore exhibiting extremely low elongation and yield strength in its ascast condition,which restricts its clinical applications.In this study,as-cast Zn–xTi(titanium)(x=0.05,0.10,0.20,and 0.30 wt.%)binary alloys were hot-rolled and their microstructures,mechanical properties,wear resistance,and cytocompatibility were comprehensively investigated for orthopedic implant applications.The microstructures of both as-cast and hot-rolled Zn–xTi alloys consisted of anα-Zn matrix phase and a TiZn16 phase,while Zn–0.2 Ti and Zn–0.3 Ti exhibited a finerα-Zn phase due to the grainrefining effect of Ti.The hot-rolled Zn–0.2 Ti alloy exhibited the highest yield strength(144.5 MPa),ultimate strength(218.7 MPa),and elongation(54.2%)among all the Zn–x Ti alloys.The corrosion resistance of Zn–xTi alloys in Hanks’solution decreased with increasing addition of Ti,and the hot-rolled Zn–0.3 Ti alloy exhibited the highest corrosion rates of 432μm/y as measured by electrochemical testing and 57.9μm/y as measured by immersion testing.The as-cast Zn–xTi alloys showed lower wear losses than their hot-rolled counterparts.The extracts of hot-rolled Zn–x Ti alloys at concentrations of≤25%showed no cytotoxicity to MG-63 osteosarcoma cells and the extracts of Zn–xTi alloys exhibited enhanced cytocompatibility with increasing Ti content. | Kun Wang Xian Tong Jixing Lin Aiping Wei Yuncang Li Matthew Dargusch Cuie Wen | 2021 | Journal of Materials Science & Technology2021，，15： | 0 |
| 13 | In-situ optical pumping for polarizing 3He neutron spin filters at the China Spallation Neutron Source显示文摘In this paper,we present the performance of a recently developed in-situ spin-exchange optically pumped^(3)He-neutron spin filter system at the China Spallation Neutron Source(CSNS).The system achieved a^(3)He polarization of over 74%at the beamline BL-20.Analysis of neutron transmission experiment results reveals a neutron polarization of>90%and an average transmission of 27%for 2.2Åneutrons,which were maintained for a duration of 120 h of beam time.To the best of our knowledge,this is the first in-situ hyperpolarized^(3)He system incorporated on a neutron beamline in China.This technology is expected to provide stable,wide-angle,and highly polarized neutrons at the CSNS for materials research and fundamental neutron physics. | Junpei Zhang Chuyi Huang Zecong Qin Fan Ye Syed Mohd Amir Ahmed Salman Yuchen Dong Long Tian Zachary Norris Buck Wolfgang Kreuzpaintner Matthew Musgrave Xin Qi Tianhao Wang Xin Tong | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，4： | 0 |
| 14 | Visualizing ordered bivariate data on node-link diagrams显示文摘Node-link visual representation is a widely used tool that allows decision-makers to see details about a network through the appropriate choice of visual metaphor.However,existing visualization methods are not always effective and efficient in representing bivariate graph-based data.This study proposes a novel node-link visual model–visual entropy(Vizent)graph–to effectively represent both primary and secondary values,such as uncertainty,on the edges simultaneously.We performed two user studies to demonstrate the efficiency and effectiveness of our approach in the context of static nodelink diagrams.In the first experiment,we evaluated the performance of the Vizent design to determine if it performed equally well or better than existing alternatives in terms of response time and accuracy.Three static visual encodings that use two visual cues were selected from the literature for comparison:Width-Lightness,Saturation-Transparency,and Numerical values.We compared the Vizent design to the selected visual encodings on various graphs ranging in complexity from 5 to 25 edges for three different tasks.The participants achieved higher accuracy of their responses using Vizent and Numerical values;however,both Width-Lightness and Saturation-Transparency did not show equal performance for all tasks.Our results suggest that increasing graph size has no impact on Vizent in terms of response time and accuracy.The performance of the Vizent graph was then compared to the Numerical values visualization.The Wilcoxon signed-rank test revealed that mean response time in seconds was significantly less when the Vizent graphs were presented,while no significant difference in accuracy was found.The results from the experiments are encouraging and we believe justify using the Vizent graph as a good alternative to traditional methods for representing bivariate data in the context of node-link diagrams. | Osman Akbulut Lucy McLaughlin Tong Xin Matthew Forshaw Nicolas S.Holliman | 2023 | Visual Informatics2023，7，3： | 0 |
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