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1Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation.Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? 2014World Journal of Gastroenterology2014,20,25:3
2Computerized physician order entry‐based system to prevent HBV reactivation in patients treated with biologic agents: The PRESCRIB project显示文摘Blanca Sampedro Cándido Hernández‐López José Ramón Ferrandiz Aitziber Illaro Emilio Fábrega Antonio Cuadrado Paula Iruzubieta Susana Menéndez Joaquín Cabezas Javier Crespo 2014Hepatology2014,,1:2
3(Ion+molecule) equilibrium technique applied to the determination of the activities of Cr2O3 and NiO--Standard molar Gibbs energy of formation ofNiCr204显示文摘RUDNYI E B KAIBICHEVA E A SIDOROV L N VARSHAVSKII M T MEN A N 1990J Chem Thermodyn1990,22,:1
4Human papillomavirus genotype attribution in invasive cervical cancer:a retrospective cross-sectional worldwide study显示文摘de Sanjose S Quint WG Alemany L Geraets DT Klaustermeier JE Lloveras B Tous S Felix A Bravo LE Shin HR Vallejos CS de Ruiz PA Lima MA Guimera N Clavero O Alejo M Llombart-Bosch A Cheng-Yang C Tatti SA Kasamatsu E Iljazovic E Odida M Prado R Seoud M Grce M Usubutun A Jain A Suarez GA Lombardi LE Banjo A Menéndez C Domingo EJ Velasco J Nessa A Chichareon SC Qiao YL Lerma E Garland SM Sasagawa T Ferrera A Hammouda D Mariani L Pelayo A Steiner I Oliva E Meijer CJ AlJassar WF Cruz E Wright TC Puras A Llave CL Tzardi M Agorastos T Garcia-Barriola V Clavel C Ordi J Andújar M Castellsagué X Sánchez GI Nowakowsld AM Bornstein J Mu(n)oz N Bosch FX Retrospective International Survey and HPV Time Trends Study Group 2010Lancet Oncol2010,11,11:1
5The functions of endothelial progenitor cells were significantly improved after treatment with intravenous immunoglobulin and aspirin in children with Kawasaki disease显示文摘Xu M G Men L N Zu Y 2011Pediatr Cardiol2011,32,4:1
6Results of a functional magnetic resonance study of the primary auditory cortex(I):general characteristics and individual outcomes显示文摘MENNDEZ-COLINO L M TRASERRA J FALC-N C 2009Acta Otorrinolaringol Esp2009,60,:1
7查看详情显示文摘Peng Y Dong M H Men X K Zong B N Zhang J L 0,,:1
8Scenario Planning: A Tool to Manage Future Water Utility Uncertainty 显示文摘Mens E Patrick R Ospina L West N 2005American Water Works Association Journal2005,97,10:1
9Application of m(o)ssbauer spectroscopy to study the formation of iron pyrite thin films显示文摘Ferrer I J Heras C D L Menéndez N 1993Journal of Materials Science1993,28,2:1
10Serum fatty acid synthase concentration is increased in patients with hepatitis viral infection and may assist in the prediction of liver steatosis显示文摘Jorge Joven Eugenia Espinel Anna Rull Raúl Beltrán-Debón Gerard Aragonès Esther Rodríguez-Gallego Jordi Camps Juan Pedro-Botet Teresa Sans Javier A. Menéndez Carlos Alonso-Villaverde 2011Journal of Clinical Virology2011,,3:1
11Safety and effi- cacy of a recombinant hepatitis E vaccine 显示文摘SHRESTHA M P SCOTT R M JOSHI D M MAM- MEN M P THAPA G B THAPA N MYINT K S A FOURNEAU M KUSCHNER R A SHRESTHA S K DAVID M P SERIWATANA J VAUGHN D W SAFARY A ENDY T P INNIS B L 2007New Engl J Med2007,356,9:1
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