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| 1 | Prognostic value of site-specific metastases in pancreatic adenocarcinoma: A Surveillance Epidemiology and End Results database analysis显示文摘AIM To evaluate the prognostic value of site-specific metastases among patients with metastatic pancreaticc arcinoma registered within the Surveillance, Epidemiology and End Results(SEER) database.METHODS SEER database(2010-2013) has been queried through SEER*Stat program to determine the presentation, treatment outcomes and prognostic outcomes of metastatic pancreatic adenocarcinoma according to the site of metastasis. In this study, metastatic pancreatic adenocarcinoma patients were classified according to the site of metastases(liver, lung, bone, brain and distant lymph nodes). We utilized chi-square test to compare the clinicopathological characteristics among different sites of metastases. We used Kaplan-Meier analysis and log-rank testing for survival comparisons. We employed Cox proportional model to perform multivariate analyses of the patient population; and accordingly hazard ratios with corresponding 95%CI were generated. Statistical significance was considered if a two-tailed P value < 0.05 was achieved. RESULTS A total of 13233 patients with stage Ⅳ pancreatic cancer and known sites of distant metastases were identified in the period from 2010-2013 and they were included into the current analysis. Patients with isolated distant nodal involvement or lung metastases have better overall and pancreatic cancer-specific survival compared to patients with isolated liver metastases(for overall survival: lung vs liver metastases: P < 0.0001; distant nodal vs liver metastases: P < 0.0001)(for pancreatic cancer-specific survival: lung vs liver metastases: P < 0.0001; distant nodal vs liver metastases: P < 0.0001). Multivariate analysis revealed that age < 65 years, white race, being married, female gender; surgery to the primary tumor and surgery to the metastatic disease were associated with better overall survival and pancreatic cancer-specific survival.CONCLUSION Pancreatic adenocarcinoma patients with isolated liver metastases have worse outcomes compared to patients with isolated lung or distant nodal metastases. Further research is needed to identify the highly selected subset of patients who may benefit from local treatment of the primary tumor and/or metastatic disease. | Hani Oweira Ulf Petrausch Daniel Helbling Jan Schmidt Meinrad Mannhart Arianeb Mehrabi Othmar Schob Anwar Giryes Michael Decker Omar Abdel-Rahman | 2017 | World Journal of Gastroenterology2017,23,10: | 13 |
| 2 | Autonomy in materials research: a case study in carbon nanotube growth显示文摘Advances in materials are an important contributor to our technological progress,and yet the process of materials discovery and development itself is slow.Our current research process is human-centred,where human researchers design,conduct,analyse and interpret experiments,and then decide what to do next.We have built an Autonomous Research System(ARES)—an autonomous research robot capable of first-of-its-kind closed-loop iterative materials experimentation.ARES exploits advances in autonomous robotics,artificial intelligence,data sciences,and high-throughput and in situ techniques,and is able to design,execute and analyse its own experiments orders of magnitude faster than current research methods.We applied ARES to study the synthesis of singlewalled carbon nanotubes,and show that it successfully learned to grow them at targeted growth rates.ARES has broad implications for the future roles of humans and autonomous research robots,and for human-machine partnering.We believe autonomous research robots like ARES constitute a disruptive advance in our ability to understand and develop complex materials at an unprecedented rate. | Pavel Nikolaev Daylond Hooper Frederick Webber Rahul Rao Kevin Decker Michael Krein Jason Poleski Rick Barto Benji Maruyama | 2016 | npj Computational Materials2016,,1: | 9 |
| 3 | Complications Associated With Double Balloon Enteroscopy at Nine US Centers显示文摘 | Lauren B. Gerson Jeffrey Tokar Michael Chiorean Simon Lo G. Anton Decker David Cave Doumit BouHaidar Daniel Mishkin Charles Dye Oleh Haluszka Jonathan A. Leighton Alvin Zfass Carol Semrad | 2009 | Clinical Gastroenterology and Hepatology2009,,11: | 2 |
| 4 | A scalable and ontology based P2P infrastructure for semantic web services显示文摘 | Mario Schlosser Michael Sintek Stefan Decker | 2002 | In Proceedings of the Second International Conference on Peer-to-Peer Computing2002,,: | 1 |
| 5 | Complications Associated With Double Balloon Enteroscopy at Nine US Centers显示文摘 | Lauren B. Gerson Jeffrey Tokar Michael Chiorean Simon Lo G. Anton Decker David Cave Doumit BouHaidar Daniel Mishkin Charles Dye Oleh Haluszka Jonathan A. Leighton Alvin Zfass Carol Semrad | 2009 | Clinical Gastroenterology and Hepatology2009,,11: | 1 |
| 6 | Gut Microbiota and Its Possible Relationship With Obesity显示文摘 | John K. DiBaise Husen Zhang Michael D. Crowell Rosa Krajmalnik-Brown G. Anton Decker Bruce E. Rittmann | 2008 | Mayo Clinic Proceedings2008,,4: | 1 |
| 7 | Predictors of Outcome in Patients With Acute Coronary Syndromes Without Persistent ST-Segment Elevation: Results From an International Trial of 9461 Patients显示文摘 | Eric Boersma Karen S. Pieper Ewout W. Steyerberg Robert G. Wilcox Wei-Ching Chang Kerry L. Lee K. Martijn Akkerhuis Robert A. Harrington Jaap W. Deckers Paul W. Armstrong A. Michael Lincoff Robert M. Califf Eric J. Topol Maarten L. Simoons | 2000 | Circulation: Journal of the American Heart Association2000,,22: | 1 |
| 8 | Creating semantic Web contents with Protégé-2000显示文摘 | Natalya F Noy Michael Sintek Stefan Decker | 2001 | IEEE Intelligent Systems2001,16,2: | 1 |
| 9 | Performance of the patency capsule compared with nonenteroclysis radiologic examinations in patients with known or suspected intestinal strictures显示文摘 | Anitha Yadav Russell I. Heigh Amy K. Hara G. Anton Decker Michael D. Crowell Suryakanth R. Gurudu Shabana F. Pasha David E. Fleischer Lucinda A. Harris Janice Post Jonathan A. Leighton | 2011 | Gastrointestinal Endoscopy2011,,4: | 1 |
| 10 | Estimating Aggregate Consumer Preferences from Online Product Reviews显示文摘 | Decker Reinhold Trusov Michael | 2010 | iNTER- NATIONAL jOURNAL of Research in Marketing2010,27,: | 1 |
| 11 | Protective effect of methylprednisolone on warm ischemia-reperfusion injury in a cholestatic rat liver显示文摘 | Gokulakkrishna Subhas Aditya Gupta Daniel Bakston Boris Silberberg Cathy Lobocki Lee Andrus Melissa Decker Vijay K. Mittal Michael J. Jacobs | 2010 | The American Journal of Surgery2010,,3: | 1 |
| 12 | Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Suspected Pulmonary Embolism显示文摘 | Francis M. Fesmire Michael D. Brown James A. Espinosa Richard D. Shih Scott M. Silvers Stephen J. Wolf Wyatt W. Decker | 2011 | Annals of Emergency Medicine2011,,6: | 1 |
| 13 | Assessing emerging technologies -Methodological challenges and the case of nanotechnologies显示文摘 | Torsten Fleischer Michael Decker and Ulrich Fiedeler | 2005 | Technological Forecasting and Social Change2005,11,9: | 1 |
| 14 | A Location Model for Communicating and Processing of Context显示文摘 | MICHAEL BEIG TOBIAS ZIMMER CHRISTIAN DECKER | 2002 | Personal and Ubiquitous Computing2002,,6: | 1 |
| 15 | Assessing merging technologies:Methodological chaIlcnges and the case of nanotechnologies显示文摘 | TORSTEN FLEISCHER MICHAEL DECKER ULRICH FIEDELER | 2005 | Technological Forecasting and Social Change2005,11,9: | 1 |
| 16 | Tomac-real - time Message Ordering in Wireless Sensor Networks Using the MAC Layer显示文摘 | Albert Krohn Michael Beigl Christian Decker | 2005 | In Proceedings of the 2nd International Workshop on Networked Sensing Systems (INSS)2005,,: | 1 |
| 17 | Association of Low Striatal Dopamine D^sub 2^ Receptor Availability With Nicotine Dependence Similar to That Seen With Other Drugs of Abuse显示文摘 | Fehr Christoph Yakushev Igor Hohmann Nina Buchholz Hans-Georg Landvogt Christian Deckers Hanna Eberhardt Alexandra Kl?ger Marie Smolka Michael N Scheurich Armin Dielentheis Thomas Schmidt Lutz G R?sch Frank Bartenstein Peter Gründer Gerhard | 2008 | The American Journal of Psychiatry2008,,4: | 1 |
| 18 | Subtotal Parathyroidectomy in Renal Failure: Still Needed after All These Years显示文摘 | P. Anthony Decker Eric P. Cohen Kara M. DoffekB.S. Blake A. Ashley Mary E. Bienemann Yong Ran Zhu Mark E. Adams Stuart D. Wilson Michael J. Demeure | 2001 | World Journal of Surgery2001,,6: | 1 |
| 19 | A Scalable and Ontology-Based P2P Infrastructure for Semantic Web Services显示文摘 | Michael Sintek Stefan Decker WolfgangNejdl | 2002 | In Proceedings of the Second International Conference on Peer-to-Peer Computing (P2P''02)2002,,: | 1 |
| 20 | Evaluation of the Reanalysis Products from GSFC, NCEP, and ECMWF Using Flux Tower Observations显示文摘 | Decker Mark Brunke Michael A Wang Zhuo Sakaguchi Koichi Zeng Xubin Bosilovich Michael G | 2012 | EN2012,,6: | 1 |