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| 1 | Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion显示文摘 | Zhenrui Li Pengxu Qian Wanqing Shao Hailing Shi Xi C. He Madelaine Gogol Zulin Yu Yongfu Wang Meijie Qi Yunfei Zhu John M. Perry Kai Zhang Fang Tao Kun Zhou Deqing Hu Yingli Han Chongbei Zhao Richard Alexander Hanzhang Xu Shiyuan Chen Allison Peak Kathyrn Hall Michael Peterson Anoja Perera Jeffrey S. Haug Tari Parmely Hua Li Bin Shen Julia Zeitlinger Chuan He Linheng Li | 2018 | Cell Research2018，28，9： | 18 |
| 2 | Fecal markers of inflammation used as surrogate markers for treatment outcome in relapsing inflammatory bowel disease显示文摘AIM: To evaluate fecal calprotectin (FC) as a surrogate marker of treatment outcome of relapse of inflammatory bowel disease (IBD) and, to compare FC with fecal myeloperoxidase (MPO) and fecal eosinophil protein X (EPX). METHODS: Thirty eight patients with IBD, comprising of 27 with ulcerative colitis (UC) and 11 with Crohn’s disease (CD) were investigated before treatment (inclusion), and after 4 and 8 wk of treatment. Treatment outcomes were evaluated by clinical features of disease activity and endoscopy in UC patients, and disease activity in CD patients. In addition, fecal samples were analyzed for FC by enzyme-linked immunosorbent assay (ELISA), and for MPO and EPX with radioimmunoassay (RIA). RESULTS: At inclusion 37 of 38 (97%) patients had elevated FC levels (> 94.7 μg/g). At the end of the study, 31 of 38 (82%) patients fulfilled predefined criteria of a complete response [UC 21/27 (78%); CD 10/11 (91%)]. Overall, a normalised FC level at the end of the study predicted a complete response in 100% patients, whereas elevated FC level predicted incomplete response in 30%. Normalised MPO or EPX levels predicted a complete response in 100% and90% of the patients, respectively. However, elevated MPO or EPX levels predicted incomplete response in 23% and 22%, respectively. CONCLUSION: A normalised FC level has the potential to be used as a surrogate marker for successful treatment outcome in IBD patients. However, patients with persistent elevation of FC levels need further evaluation. FC and MPO provide superior discrimination than EPX in IBD treatment outcome. | Michael Wagner Christer GB Peterson Peter Ridefelt Per Sangfelt Marie Carlson | 2008 | World Journal of Gastroenterology2008，14，36： | 9 |
| 3 | 21世纪的卒中新定义:美国心脏协会/美国卒中协会对医疗专业人员的声明显示文摘尽管脑血管病的影响广泛且对其病理生理学的理解已取得一些进展,但“卒中”一词在临床实践、临床研究和公共卫生评价中的定义并不统一。经典的卒中定义主要是临床定义,不能反映科学技术的进步。因此,美国心脏协会卒中委员会/美国卒中协会召集了一个写作组,旨在对21世纪的卒中新定义制定一份专家共识文件。中枢神经系统(centralnervoussystem,CNS)梗死被定义为缺血导致的脑、脊髓或视网膜细胞死亡,并且具有永久性损伤的神经病理学、神经影像学和(或)临床证据。CNS梗死具有一系列临床表现:缺血性卒中特指伴有明显症状的CNS梗死,而无症状梗死则顾名思义不引起明显症状。广义的卒中还包括脑出血和蛛网膜下腔出血。卒中的新定义结合了临床和组织学标准,因此能被融入临床实践、研究和公共卫生评价。 | Ralph L. Sacco Scott E. Kasner Joseph P. Broderick Louis R. Caplan J.J. (Buddy) Connors Antonio Culebras Mitchell S.V. Elkind Mary G. George Allen D. Hamdan Randall T. Higashida Brian L. Hoh L. Scott Janis Carlos S. Kase Dawn O. Kleindorfer Jin-Moo Lee Michael E. Moseley Eric D. Peterson Tanya N. Turan Amy L. Valderrama Harry V. Vinters 王胜男(译) 吴齐恒(译) 邓镇(译) 周晓(译) 袁超(译) 潘速跃(译) | 2014 | 国际脑血管病杂志2014，22，1： | 7 |
| 4 | 2012 ACCF/AHA Focused Update Incorporated Into the ACCF/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction显示文摘 | Jeffrey L. Anderson Cynthia D. Adams Elliott M. Antman Charles R. Bridges Robert M. Califf Donald E. Casey William E. Chavey Francis M. Fesmire Judith S. Hochman Thomas N. Levin A. Michael Lincoff Eric D. Peterson Pierre Theroux Nanette K. Wenger R. Scott | 2013 | Journal of the American College of Cardiology2013，，23： | 2 |
| 5 | Comparison of Hybrid Coronary Revascularization Versus Coronary Artery Bypass Grafting in Patients ≥65 Years With Multivessel Coronary Artery Disease显示文摘 | Ralf E. Harskamp John D. Puskas Jan G. Tijssen Patrick F. Walker Henry A. Liberman Renato D. Lopes Thomas A. Vassiliades Eric D. Peterson Michael E. Halkos | 2014 | The American Journal of Cardiology2014，，： | 2 |
| 6 | DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival显示文摘 | Timothy R. Peterson Mathieu Laplante Carson C. Thoreen Yasemin Sancak Seong A. Kang W. Michael Kuehl Nathanael S. Gray David M. Sabatini | 2009 | Cell2009，，5： | 2 |
| 7 | HLA-restricted NY-ESO-1 peptide immunotherapy for metastatic castration resistant prostate cancer显示文摘 | Guru Sonpavde Mingjun Wang Leif E. Peterson Helen Y. Wang Teresa Joe Martha P. Mims Dov Kadmon Michael M. Ittmann Thomas M. Wheeler Adrian P. Gee Rong-Fu Wang Teresa G. Hayes | 2014 | Investigational New Drugs2014，，2： | 2 |
| 8 | 2012 ACCF/AHA Focused Update of the Guideline for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction (Updating the 2007 Guideline and Replacing the 2011 Focused Update)显示文摘 | Hani Jneid Jeffrey L. Anderson R. Scott Wright Cynthia D. Adams Charles R. Bridges Donald E. Casey Steven M. Ettinger Francis M. Fesmire Theodore G. Ganiats A. Michael Lincoff Eric D. Peterson George J. Philippides Pierre Theroux Nanette K. Wenger James P | 2012 | Journal of the American College of Cardiology2012，，7： | 1 |
| 9 | Nonin- vasive positive pressure ventilation in subjects with stable COPD 显示文摘 | Bhatt Surya P Peterson Michael W Wilson Jeffrey S | 2013 | Int J Chron Obstruct Pulmon Dis2013，8，： | 1 |
| 10 | 2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction显示文摘 | R. Scott Wright Jeffrey L. Anderson Cynthia D. Adams Charles R. Bridges Donald E. Casey Steven M. Ettinger Francis M. Fesmire Theodore G. Ganiats Hani Jneid A. Michael Lincoff Eric D. Peterson George J. Philippides Pierre Theroux Nanette K. Wenger James P | 2011 | Journal of the American College of Cardiology2011，，19： | 1 |
| 11 | Hybrid Algorithm for Robust, Real- Time Source Localization in Reverberant Environments 显示文摘 | Michael Peterson J Chris Kyriakakis | 2005 | ICASSP2005，，： | 1 |
| 12 | Utilization and Impact of Pre-Hospital Electrocardiograms for Patients With Acute ST-Segment Elevation Myocardial Infarction显示文摘 | Deborah B. Diercks Michael C. Kontos Anita Y. Chen Charles V. Pollack Stephen D. Wiviott John S. Rumsfeld David J. Magid W. Brian Gibler Christopher P. Cannon Eric D. Peterson Matthew T. Roe | 2009 | Journal of the American College of Cardiology2009，，2： | 1 |
| 13 | Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): Comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes显示文摘 | Christopher P. Cannon Robert P. Giugliano Michael A. Blazing Robert A. Harrington John L. Peterson Christine McCrary Sisk John Strony Thomas A. Musliner Carolyn H. McCabe Enrico Veltri Eugene Braunwald Robert M. Califf | 2008 | American Heart Journal2008，，5： | 1 |
| 14 | Determinants of citizens’ attitudes toward police: Results of the Harrisburg Citizen Survey - 1999显示文摘 | Barbara Sims Michael Hooper Steven A. Peterson | 2002 | Policing: An International Journal of Police Strategies & Management2002，，3： | 1 |
| 15 | D-Cycloserine Augmented Exposure Therapy for Obsessive-Compulsive Disorder显示文摘 | Matt G. Kushner Suck Won Kim Christopher Donahue Paul Thuras David Adson Michael Kotlyar James McCabe Jillian Peterson Edna B. Foa | 2007 | Biological Psychiatry2007，，： | 1 |
| 16 | 加快大型数据中心服务的可重构结构显示文摘数据中心的工作负载要求高计算能力、灵活性、能效和低成本。同时改善所有这些因素非常具有挑战性。为了推进数据中心超出商用服务器设计可以提供的能力,我们设计并构建了一个可组合、可重构的结构,来加速部分大型软件服务。结构的每个实例都由嵌入48台机器的半机架6×8二维环面高端Stratix V FPGA组成。每台服务器中都放置了一个FPGA,可以通过PCIe来访问,并用成对的10 Gb SAS电缆直接连接到其他FPGA。在本文中,我们描述了这种结构在1,632台服务器组(bed)的中等规模的部署,并测量了其在加快Bing搜索引擎方面的功效。我们描述了系统的要求和架构,详细介绍了关键技术挑战,以及使系统在出现故障情况下保持鲁棒性所需的解决方案,还有根据排名候选文档测量的系统性能、功率和弹性。在高负载时,一定范围内的可重构结构提高了每台服务器固定延迟分布的吞吐量排名95%——或在保持等效吞吐量时,减少29%的尾延迟。 | Andrew Putnam Adrian M.Caulfield Eric S.Chung Derek Chiou Kypros Constantinide John Demme Hadi Esmaeilzadeh Jeremy Fowers Gopi Prashanth Gopal Jan Gray Michael Haselman Scott Hauck Stephen Heil Amir Hormati Joo-Young Kim Sitaram Lanka James Larus Eric Peterson Simon Pope Aaron Smith Jason Thong Phillip Yi Xiao Doug Burger | 2015 | 中国集成电路2015，24，1： | 1 |
| 17 | Germline BHD-Mutation Spectrum and Phenotype Analysis of a Large Cohort of Families with Birt-Hogg-Dubé Syndrome显示文摘 | Laura S. Schmidt Michael L. Nickerson Michelle B. Warren Gladys M. Glenn Jorge R. Toro Maria J. Merino Maria L. Turner Peter L. Choyke Nirmala Sharma James Peterson Patrick Morrison Eamonn R. Maher McClellan M. Walther Berton Zbar W. Marston Linehan | 2005 | The American Journal of Human Genetics2005，，6： | 1 |
| 18 | CD4 + CD25 + Foxp3 + Regulatory T Cells Promote Th17 Cells In Vitro and Enhance Host Resistance in Mouse Candida albicans Th17 Cell Infection Model显示文摘 | Pushpa Pandiyan Heather R. Conti Lixin Zheng Alanna C. Peterson Douglas R. Mathern Nydiaris Hernández-Santos Mira Edgerton Sarah L. Gaffen Michael J. Lenardo | 2011 | Immunity2011，，： | 1 |
| 19 | Acute traumatic spinal epidural hematoma: imaging and neurologic outcome显示文摘 | D. Lee Bennett Michael J. George Kenjirou Ohashi Georges Y. El-Khoury Joshua J. Lucas Matthew C. Peterson | 2005 | Emergency Radiology2005，，3： | 1 |
| 20 | 2011 ACCF/AHA Focused Update of the Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction (Updating the 2007 Guideline)显示文摘 | R. Scott Wright Jeffrey L. Anderson Cynthia D. Adams Charles R. Bridges Donald E. Casey Steven M. Ettinger Francis M. Fesmire Theodore G. Ganiats Hani Jneid A. Michael Lincoff Eric D. Peterson George J. Philippides Pierre Theroux Nanette K. Wenger James P | 2011 | Journal of the American College of Cardiology2011，，19： | 1 |
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