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| 1 | 冠状动脉内影像学临床应用专家共识(第一部分):对冠状动脉介入治疗的指导与优化显示文摘欧洲心血管介入协会(EAPCI)专家组系统总结了血管内超声(IVUS)和光学相干断层成像(OCT)这两种血管内影像学检查临床应用指征的现有证据,提供了关于IVUS和OCT指导经皮冠状动脉介入治疗(PCI)的应用价值,并明确了最可能从腔内影像学指导的介入治疗中获得临床收益的患者或病变类型,同时详细论述了PCI前如何使用IVUS或OCT优化支架尺寸(支架长度和直径)和手术策略的选择。此外,专家推荐对支架失败(支架内再狭窄或支架内血栓形成)的患者应常规进行冠状动脉内影像学检查,并首选OCT。最后,重点论述了IVUS和OCT在指导PCI和评估支架失败两个方面的优势和局限性,并对未来需要深入研究的领域进行了展望。 | Lorenz Raber Gary S Mintz Konstantinos C Koskinas Thomas W Johnson Niels R Holm Yoshinubo Onuma Maria D Radu Michael Joner Bo Yu Haibo Jia Nicolas Meneveau Jose M.de la Torre Hemandez Javier Escaned Jonathan Hill Francesco Prati Antonio Colombo Carlo di Mario Evelyn Regar Davide Capodanno William Wijns Robert A Byme Giulio Guagliumi | 2019 | 中华心血管病杂志2019，47，1： | 17 |
| 2 | Nat Biotechnol:将人星形胶质细胞重编程为多巴胺能神经元,有助治疗帕金森病显示文摘帕金森病是一种主要影响运动系统的神经退行性疾病。它的特征在于大脑中的多巴胺能神经元(dopaminergic neuron)渐进性丧失。尽管当前的疗法旨在补充多巴胺水平,但是没有一种疗法能够恢复这些丢失的细胞。如今。在一项新的研究中,来自瑞典、奥地利、西班牙和美国的研究人员开发出一种方法:将神经胶质细胞(glialcell)转化为活性的多巴胺能神经元,并且所产生的多巴胺能神经元能够部分恢复帕金森病模式小鼠的运动功能。这项概念验证研究可能为开发出一种治疗这种疾病的新方法铺平道路。 | Pia Rivetti di Val Cervo, Elisa Martín-Montañez, Enrique M Toledo, Gioele La Manno, Sara Padrell Sánchez, Sten Linnarsson Ernest Arenas Roman A Romanov, Christian Pifl Tibor Harkany Roman A Romanov, Giada Spigolon, Débora Masini, Michael Feyder, Tibor Harkany Gilberto Fisone Elisa Martín-Montañez Yi-Han Ng Marius Wernig | 2017 | 现代生物医学进展2017，17，17： | 11 |
| 3 | Video capsule endoscopy in left ventricular assist device recipients with obscure gastrointestinal bleeding显示文摘AIM: To assess whether video capsule endoscopy(VCE) affects the outcomes of left ventricular assist devices(LVADs) recipients with gastrointestinal bleeding.METHODS: This is a retrospective study of LVAD recipients with obscure gastrointestinal bleeding(OGIB) who underwent VCE at a tertiary medical center between 2005 and 2013. All patients were admitted and monitored with telemetry and all VCE and subsequent endoscopic procedures were performed as inpatients. A VCE study was considered positive only when P2 lesions were found and was regarded as negative if P1 or P0 were identified. All patients were followed until heart transplant, death, or the end of the study.RESULTS: Between 2005 and 2013, 30 patients with LVAD underwent VCE. Completion rate of VCE was 93.3% and there was no capsule retention. No interference of VCE recording or the function of LVAD was found. VCE was positive in 40% of patients(n = 12). The most common finding was active small intestinal bleeding(50%) and small intestinal angiodysplasia(33.3%). There was no difference in the rate of recurrent bleeding between patients with positive and negative VCE study(50.0% vs 55.6%,P = 1.00) during an average of 11.6 ± 9.6 mo follow up. Among patients with positive VCE, the recurrent bleeding rate did not differ whether subsequent endoscopy was performed(50% vs 50%, P = 1.00).CONCLUSION: VCE can be safely performed in LVAD recipients with a diagnostic yield of 40%. VCE does not affect recurrent bleeding in LVAD patients regardless of findings. | Surachai Amornsawadwattana Michael Nassif David Raymer Shane La Rue Chien-Huan Chen | 2016 | World Journal of Gastroenterology2016，22，18： | 2 |
| 4 | Long-term Anastomotic Complications After Pancreaticoduodenectomy for Benign Diseases显示文摘 | Kaye M. Reid-Lombardo Antonio Ramos-De la Medina Kristine Thomsen William S. Harmsen Michael B. Farnell | 2007 | Journal of Gastrointestinal Surgery2007，，12： | 1 |
| 5 | Open source software for workflow management: The case of YAWL 显示文摘 | Michael Adams Arthur HM ter Hofstede Marcello La Rosa | 2011 | IEEE Software2011，28，3： | 1 |
| 6 | BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells显示文摘 | Stephanie Beurlet Nader Omidvar Petra Gorombei Patricia Krief Carole Le Pogam Niclas Setterblad Pierre de la Grange Christophe Leboeuf Anne Janin Maria-Elena Noguera Florence Hervatin Laure Sarda-Mantel Marina Konopleva Michael Andreeff Andrea W. Tu Alice | 2013 | Blood2013，，16： | 1 |
| 7 | Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3 trial显示文摘 | Michael Manns Patrick Marcellin Fred Poordad Evaldo Stanislau Affonso de Araujo Maria Buti Yves Horsmans Ewa Janczewska Federico Villamil Jane Scott Monika Peeters Oliver Lenz Sivi Ouwerkerk-Mahadevan Guy De La Rosa Ronald Kalmeijer Rekha Sinha Maria Beum | 2014 | The Lancet2014，，： | 1 |
| 8 | Fiber Bragg grating interrogation and multiplexing with a 3×3 coupler and a scanning filter显示文摘 | Gregg J Todd Michael D Bryan LA | 2006 | Journal of lightwave technology2006，8，18： | 1 |
| 9 | Laparoscopic commonbile duct exploration显示文摘 | KaraBeth BM Gina LA Michael JM | 2004 | Current Surgery2004，61，3： | 1 |
| 10 | ATP7B Mediates Vesicular Sequestration of Copper: Insight Into Biliary Copper Excretion显示文摘 | Michael A. Cater Sharon La Fontaine Kristy Shield Yolanda Deal Julian F.B. Mercer | 2006 | Gastroenterology2006，，2： | 1 |
| 11 | Rapid Turnover of Connexin43 in the Adult Rat Heart显示文摘 | Michael A. Beardslee James G. Laing Eric C. Beyer Jeffrey E. Saffitz | 1998 | Circulation Research1998，，6： | 1 |
| 12 | Combined venous sinus angioplasty and low-dose thrombolytic therapy for treatment of hemorrhagic transverse sinus thrombosis in a pediatric patient显示文摘 | Michaels LA Roychowdhury S | 2006 | J Pediatr Hematol Oneol2006，28，： | 1 |
| 13 | Suction dressings to secure a dermal substitute显示文摘 | Winston McEwan Tim La H Brown Stephen M Mills Michael J Muller | 2003 | Burns2003，，： | 1 |
| 14 | Help-Seeking Experiences and Attitudes among African American,Asian American,and European American College Students显示文摘 | Akihiko M Page LA Michael PT | 2009 | Int J Adv Counsel2009，31，： | 1 |
| 15 | Opposite actions of brain --derived neurotrophie factor and neurotrophin--3 on firing features and Ion channel composition of murine spiral gangli- on neurons显示文摘 | Crista LA Michael AR Robin LD | 2002 | The Journal of Neuroseience2002，22，： | 1 |
| 16 | Clinical Utility of Objective Tests for Dry Eye Disease: Variability Over Time and Implications for Clinical Trials and Disease Management显示文摘 | Benjamin D. Sullivan Leslie A. Crews Bar? S?nmez Maria F. de la Paz Ebru Comert Victor Charoenrook Aline L. de Araujo Jay S. Pepose Michael S. Berg Valerie P. Kosheleff Michael A. Lemp | 2012 | Cornea2012，，9： | 1 |
| 17 | Test results of concrete thermal energy storage for parabolic trough power plants 显示文摘 | Doerte Laing Dorothea Lehmann Michael FiB Bahl Carsten | 2009 | Journal of Solar Energy Engineering2009，131，4： | 1 |
| 18 | Valve-Sparing Aortic Root Replacement: Early and Midterm Outcomes in 83 Patients显示文摘 | Joseph S. Coselli Michael S. Hughes Susan Y. Green Matt D. Price Samantha Zarda Kim I. de la Cruz Ourania Preventza Scott A. LeMaire | 2014 | The Annals of Thoracic Surgery2014，，4： | 1 |
| 19 | Newly diagnosedimmune thrombocytopenia in children and adults : a comparative pro-spective observational registry of the Intercontinental Cooperative Im-mune Thrombocytopenia Study Group 显示文摘 | KUHNE T BERCHTOLD W MICHAELS LA | 2011 | Haematologica2011，96，12： | 1 |
| 20 | High-quality diesel from hexose-and pentose-derived biomass platform molecules 显示文摘 | AVELINO CORMA OLALLA DE LA TORRE MICHAEL RENZ | 2011 | Chem- suschem2011，4，11： | 1 |
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