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| 1 | Diagenetic and Mineralization Age of the Hehuaping Tin-polymetallic Orefield,Hunan Province显示文摘摘要:Hehuaping 听存款是在地质的调查期间在最近的年里发现的大存款。发现的听存款在在在泥盆纪碳酸盐岩石(Qiziqiao 形成) 和沙岩(Tiaomajian 形成) 之间的 interstratifled 破裂地区开发的差错地区,而且存款包括不仅岩石改变类型存款。发现后者类型的听存款极大地在著名 Nanling polymetallic metallogenetic 区域充实听矿化作用类型并且可以为在这个区域听存款勘探向我们提供新潜在的取向。在 Nanling 区域形成听存款应该与 Yanshanian 有关而不是 Indosinian 花岗石的 magmatism,这通常被相信。系统的锆石 U-Pb 虾在这份报纸标明日期证明听矿化作用忍受了至少二个阶段。早阶段应该与 Wangxianling 花岗石的主要身体的侵入有关,它在 Indosinian 期间是 emplaced 有 diagenetic 和 224.0 | WEI Daofang BAO Zhengyu FU Jianming CAI Minghai | 2007 | Acta Geologica Sinica(English Edition)2007，81，2： | 23 |
| 2 | Does top executives' US experience matter? Evidence from US-listed Chinese firms显示文摘Foreign firms face enormous obstacles in attracting investors and analysts when issuing securities in the United States.We use US-listed Chinese firms as our research sample and find that firms that hire top executives(i.e.,Chief Executive Officer[CEO]or Chief Financial Officer[CFO]) with work experience in the US or educational qualifications from the US attract more US institutional investors and analysts.Further,we find that CFOs' US experience dominates the results.Corroborating our results,we further find that firms with US-experienced CFOs are more likely to hold conference calls and voluntarily issue management forecasts,which suggests that CFOs with a US background are better at communicating with US investors and analysts and acting in alignment with US norms compared with Chinese CFOs.Collectively,our results suggest that hiring a CFO with a US background could facilitate cross-listed foreign firms to lower US investors' and analysts' information disadvantage. | Jingjing Li Minghai Wei Bingxuan Lin | 2016 | China Journal of Accounting Research2016，，4： | 4 |
| 3 | In-situ emb e dding zeolitic imidazolate framework derived Co–N–C bifunctional catalysts in carbon nanotube networks for flexible Zn–air batteries显示文摘Recently, the development of high-performance bifunctional oxygen catalysts integrated with flexible conductive scaffolds f or rechargeable metal-air batteries has attracted considerable interest, driving by fastgrowing wearable electronics. Herein, we report a flexible bifunctional oxygen catalyst thin film consisting of Co–N–C bifunctional catalysts embedding in carbon nanotube(CNT) networks. The catalyst is readily prepared by pyrolysis of cobalt-based zeolitic imidazolate frameworks(ZIF-67) that are in-situ synthesized in CNT networks. Such catalyst film demonstrates very high catalytic activities for oxygen reduction(onset potential: 0.91 V, and half-wave potential: 0.87 V vs. RHE) and oxygen evolution(10 m Acm^-2 at 1.58 V) reactions, high methanol tolerance property, and long-term stability(97% current retention). Moreover, our integrated catalyst film shows very good structure flexibility and robustness. Based on the obtained film air electrodes, flexible Zn–air batteries demonstrate low charging and discharging overpotentials(0.82 V at 1 m A cm^-1) and excellent structure stability in the bending tests. These results indicate that presently reported catalyst films are potential air electrodes for flexible metal–air batteries. | Bo Lv Sha Zeng Wei Yang Jian Qiao Chao Zhang Chengfeng Zhu Minghai Chen Jiangtao Di Qingwen Li | 2019 | Journal of Energy Chemistry2019，28，11： | 2 |
| 4 | Impacts of space-time-frequency synchronization errors onwide-band target echo characteristics of bistatic/multistatic radar显示文摘Bistatic/multistatic radar has great potential advantages over its monostatic counterpart. However, the separation of a transmitter and a receiver leads to difficulties in locating the target position accurately and guaranteeing space-timefrequency synchronization of the transmitter and the receiver.The error model of space-time-frequency synchronization in a motion platform of bistatic/multistatic radar is studied. The relationship between the space synchronization error and the transmitter platform position, receiver platform position, moving state, and beam pointing error, is analyzed. The effect of space synchronization error on target echo power is studied. The target scattering characteristics are restructured by many separate scattering centers of the target in high frequency regions. Based on the scattering centers model of the radar target, this radar target echo model and the simulation method are discussed. The algorithm of bistatic/multistatic radar target echo accurately reflects the scattering characteristics of the radar target, pulse modulation speciality of radar transmitting signals, and spacetime-frequency synchronization error characteristics between the transmitter station and the receiver station. The simulation of bistatic radar is completed in computer, and the results of the simulation validate the feasibility of the method. | Minghai Pan Qinghua Han Shufeng Gong Weijun Long Haitao Wei | 2016 | Journal of Systems Engineering and Electronics2016，27，3： | 2 |
| 5 | DNA methylation and alternative splicing modulate FBXW11 gene expression in Holstein bull testis and are correlated with sperm quality显示文摘F-box and WD-40 domain protein 11(FBXW11)is an important component of the E3 ubiquitin-ligase enzyme that plays a key role in the ubiquitin-dependent regulation of spermatogenesis.In our previous research,the mRNA expression of FBXW11 in bull sperm with high motility is significantly higher than that with low motility.In the present study,the protein expression levels of FBXW11 in bull testicular tissues with low-performance sperm quality groups were significantly higher than those in normal performance groups.The immunohistochemistry result demonstrated that FBXW11 protein was located in the periphery of Leydig cells and seminiferous tubules.Three splice variants of the FBXW11 gene,namely,FBXW11-tv1,FBXW11-tv2,and FBXW11-tv3,were identified in testicular tissues.The splicing patterns of the three variants are exon skipping.The transcript FBXW11-tv2 expressions were the highest in each sample.The low-performance groups displayed higher FBXW11-tv1 and FBXW11-tv2 transcript expressions than the normal performance groups.Two CpG islands were located within the 5’UTR and exon 1-2 region of the FBXW11 gene.Bisulfite sequencing PCR results demonstrated that the methylation levels of 11 methylation sites in the CpG island 2 from−99 to−43 in the normal performance groups were significantly lower than those in the low-performance groups.Pearson correlation analysis suggested that the CpG island 2 methylation level was negatively correlated with sperm motility and the transcript FBXW11-tv2 expression level.Our data revealed that alternative splicing and DNA methylation jointly regulated FBXW11 gene expression and were correlated with sperm quality traits during spermatogenesis in Holsteins. | YONG LIU ZHIHUA JU QIANG JIANG WENHAO LIU CHUNHONG YANG YARAN ZHANG XIUGE WANG YAPING GAO XIAOCHAO WEI YAN SUN JINPENG WANG MINGHAI HOU LING YANG JINMING HUANG | 2021 | BIOCELL2021，45，1： | 1 |
| 6 | Variation in winter daily range area of red deer(Cervus elaphus xanthopygus) based on DNA extracted from fecal samples显示文摘With environmental change and increased human activity,wild red deer(Cervus elaphus xanthopygus)populations and habitat area continue to decrease.Red deer is a main prey species of Amur tiger(Panthera tigris altaica).Factors affecting red deer winter home range in the Wanda montains of northeast China are not well understood.In this study,we aimed to better document red deer daily ranges to support conservation of red deer.A second objective was to develop a practical research method combining macro-and micro-technology for home range research on a variety of rare or endangered wild species.We collected 105 fresh fecal samples of red deer in three different periods during winter from December 2012 to March 2013 in the Wandashan region,Heilongjiang Province,China.Individual and sex identities were analyzed based on fecal DNA using microsatellite DNA.We used samples from deer farms for correction and validation of our identifications from field samples.We used a combination of molecular scatology,3S techniques(GPS),and direct observation to estimate winter daily range areas.Based on eleven microsatellite loci,we identified 18 individuals,10 females and 8 males,with a correction factor of 1.00 and sex ratio of 1:0.8.The mean(±SE)number of alleles was 5.1±0.41,and mean polymorphism information content was 0.63±0.03.Expected heterozygosity ranged from 0.46 to 0.81,with a mean of 0.69±0.03,and mean observed heterozygosity was 0.73±0.07.Sizes of mean daily ranges were 26.1±1.1 ha in December,89.3±1.6 ha in January,and 67.5±1.9 ha in March,indicating the following trend for daily range area:middle winter>late winter>early winter.Mean daily range area was insignificantly larger for males than for females.Estimated winter daily ranges were similar to those reported for Europe.Our combination of macro-and micro-technology proved useful for estimating winter home range areas of red deer. | Miao Yang Yue Sun Wei Qi Zhang Hongyi Yuan Minghai Zhang | 2019 | Journal of Forestry Research2019，30，5： | 1 |
| 7 | How does the relationship between multiple large shareholders affect corporate valuations? Evidence from China显示文摘 | Minying Cheng Bingxuan Lin Minghai Wei | 2013 | Journal of Economics and Business2013，，： | 1 |
| 8 | HDAC I/IIb selective inhibitor Purinostat Mesylate combined with GLS1 inhibition effectively eliminates CML stem cells显示文摘Purinostat Mesylate(PM)is a novel highly selective and active HDAC I/IIb inhibitor,and the injectable formulation of PM(PMF)based on the compound prescription containing cyclodextrin completely can overcome PM’s poor solubility and improves its stability and pharmacokinetic properties.Here,we showed that PM effectively repressed the survival of Ph+leukemia cells and CD34+leukemia cells from CML patients in vitro.In vivo studies demonstrated that PMF significantly prevented BCR-ABL(T315I)induced CML progression by restraining leukemia stem cells(LSCs),which are insensitive to chemotherapy and responsible for CML relapse.Mechanism studies revealed that targeting HDAC I/IIb repressed several important factors for LSCs survival including c-Myc,β-Catenin,E2f,Ezh2,Alox5,and mTOR,as well as interrupted some critical biologic processes.Additionally,PMF increased glutamate metabolism in LSCs by increasing GLS1.The combination of PMF and glutaminase inhibitor BPTES synergistically eradicated LSCs by altering multiple key proteins and signaling pathways which are critical for LSC survival and self-renewal.Overall,our findings represent a new therapeutic strategy for eliminating LSCs by targeting HDAC I/IIb and glutaminolysis,which potentially provides a guidance for PMF clinical trials in the future for TKI resistance CML patients. | Qiang Qiu Linyu yang Yunyu Feng Zejiang Zhu Ning Li Li Zheng Yuanyuan Sun Cong Pan Huandi Qiu Xue Cui Wei He Fang Wang Yuyao Yi Minghai Tang Zhuang Yang Yunfan Yang Zhihui Li Lijuan Chen Yiguo Hu | 2023 | Bioactive Materials2023，，3： | 1 |
| 9 | Melphalan-loaded methoxy poly(ethylene glycol)-poly(D,L-lactide)copolymer nanomicelles in the treatment of multiple myeloma显示文摘Multiple myeloma(MM)is the second most common hematological tumor characterized by the proliferation of monoclonal plasma cells.Melphalan(MEL)is commonly used in the treatment of MM and is especially essential for patients undergoing autologous stem cell transplantation(ASCT).Although many drugs for MM have been developed in recent years,chemotherapy followed by ASCT remains the optimal option.Melphalan,the backbone of the conditioning regimen,brings severe toxicities at a high dose.Nanodrug delivery systems enable drugs to be highly effective and have low toxicity.In this study,methoxy poly(ethylene glycol)-poly(D,L-lactide)copolymer(MPEG-PDLLA)was chosen to encapsulate melphalan,and the characteristics,effectiveness,and safety of MEL/MPEG-PDLLA in vitro and in vivo were investigated.MEL/MPEG-PDLLA showed slow release and was easily engulfed by MM cells despite a result of the antitumor assay comparable to that of free melphalan in vitro.The in vivo results showed that MEL/MPEG-PDLLA could significantly alleviate tumor burden and prolong survival time without increasing the toxicity to vital organs.In addition,MEL/MPEG-PDLLA could significantly reduce the damage to the intestinal mucosa caused by melphalan.In conclusion,MEL/MPEG-PDLLA shows improved antitumor activity and has the potential to alleviate pains of MM patients undergoing ASCT. | Yingying Chen Qiang Zeng Bingyang Chu Zhigang Liu Xue Wei Mengran Chen Peipei Yang Minghai Tang Ting Niu Yongqian Jia Ying Qu Zhiyong Qian | 2023 | Chinese Chemical Letters2023，34，9： | 0 |
| 10 | Enhancing stimulated Brillouin scattering in the waveguide grating显示文摘We obtain the enhanced stimulated Brillouin scattering(SBS)by adding the optimized Bragg grating to an As_(2)S_(3) chalcogenide half suspended-core rectangle waveguide.The half suspended-core waveguide grating is characterized by the period of 344.67 nm and the refractive index modulation depth of 0.0001.Through simulation experiments,the obtained Brillouin gain is 58.5 dB and the 3 dB bandwidth can reduce to 7.8 MHz.The half suspended-core waveguide structure can decrease the size of the chip while the periodic structure can enhance the slow light effect,so we have improved the integration of the waveguide and enhanced SBS by combining these two advantages. | WANG Minghai CUI Fengtao YANG Yang DONG Wei | 2022 | Optoelectronics Letters2022，18，3： | 0 |
| 11 | ISAR Imaging and Cross-Range Scaling Based on Image Rotation Correlation显示文摘With the rapid advancement of technology,not only do we need to acquire a clear in-verse synthetic aperture radar(ISAR)image,but also the real size of the target on the imaging plane,so it’s particularly important for the ISAR to rescale the images.That is,the ISAR image which is in the range-Doppler domain is converted into the range-azimuth domain.Actually,the key point to solving the problem is to estimate the rotation parameters.In this paper,a new scheme to rescale the images is proposed.For the sake of solving the problem of two-dimensional image blur and target high-speed,the instantaneous range instantaneous Doppler(IRID)method is used to obtain ISAR images,and the rotation parameters are estimated by comparing the rotation correlation of the two images.Using this method,the error of the estimated rotation parameters is greatly reduced,so that the target can be rescaled accurately.The simulation results verify the ef-fectiveness of the proposed algorithm. | Fangming Liu Cong Du Yujiao Ding Minghai Wang Wei Dong | 2022 | Journal of Beijing Institute of Technology2022，31，2： | 0 |
| 12 | Inhibitory effects of cytosine deaminase gene-transfected bone marrow mesenchymal stem cells on glioma cell proliferation显示文摘Bone marrow mesenchymal stem cells were isolated from C57BL mice,transfected with the cytosine deaminase(CD) gene using a lentivirus vector and co-cultured with C6 glioma cells to verify anti-tumor effects of bone marrow mesenchymal stem cells carrying CD genes.C57MSC-CD/eGFP cells converted 5-fluorocytosine to 5-fluorouracil and exhibited significant inhibition of proliferation and apoptosis in C6 glioma cells.C57MSC-CD/eGFP cells were then implanted into rat models of brain C6 glioma.Rats were also intraperitoneally injected with 5-fluorocytosine after 7 days.MSC-CD/eGFP cells were irregularly distributed at the margin of the glioma,as well as encased and reduced the volume of the glioma.CD-transfected bone marrow mesenchymal stem cells inhibit the in vivo growth and in vitro proliferation of glioma. | Fei Song Qi Xing Kedong Song Jian Liu Guangchun Ji Yufang Ma Tianqing Liu Minghai Wei Xuehu Ma | 2011 | Neural Regeneration Research2011，6，16： | 0 |
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