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| 1 | Prediction of the outcome of transplantation in man by platelet adherence in donor liver allografts: evidence of the importance of prepreservation injury显示文摘 | Cywes R Mullen J B Stratis MA | 1993 | Transplantation1993，56，2： | 1 |
| 2 | Value of the electrocardiaogram in diagnosing the number of severely narrowed coronary arteries in rest angina pectoris显示文摘 | Vos MA Mulleneer R | 1993 | Am J Cardiol1993，72，1： | 1 |
| 3 | value of the electrocardio gram in diagnosing the number of severely narrowed coronary anteries in rest angina pectoris 显示文摘 | Gorgels APM Vos MA Mulleneers R | 1993 | Am J Cardiol1993，72，： | 1 |
| 4 | Nerve depen-dency of regeneration:The role of Distal-less and FGF signaling in amphibian limb regeneration显示文摘 | Mullen LM Bryant SV Torok MA | | 0，，11： | 1 |
| 5 | Value of the electrocardiogram in diagnosing the number of severely narrowedcoronary arteries in rest angina pectoris显示文摘 | Gorgels APM Vos MA Mulleneers R | 1993 | Am J Cardiol1993，72，14： | 1 |
| 6 | Value of the electrocardiogram in diagnosing the number of severely narrowed coronary arteries in rest angina pectoris显示文摘 | Gorgels APM Vos MA Mulleneers R | 1993 | Am J Cardiol1993，72，14： | 1 |
| 7 | Value of the electrocardiogram in diagnosing the number of severely narrowed coronary arteries in rest angina pectoris显示文摘 | Gorgels AP Vos Ma Mulleneers R | 1993 | Am J Cardiol1993，72，14： | 1 |
| 8 | Value of the electrocardiogram in diagnosing the numberof severely narrowed coronary arteries in rest angina pectoris显示文摘 | Gorgels AP Vos MA Mulleneers R | 1993 | Am J Cardiol1993，72，14： | 1 |
| 9 | Integrated muhidisciplinary care in Parkinson's disease: a non - randomised, controlled trial (IMPACT) 显示文摘 | VAN DER MARCK MA MUNNEKE M MULLENERS W | 2013 | Lancet Neurol2013，12，10： | 1 |
| 10 | Value of electrocardiogram in diognosing the number of severly narrowed coronary arteries in rest angina pectoris 显示文摘 | Vos MA Mulleneers R | 1993 | Am J Cardiol1993，72，： | 1 |
| 11 | Value of the electrocardi- ogram in diagnosing the number of severely narrowed coronary ar- teries in rest angina pectoris 显示文摘 | Gorgels AP Vos MA Mulleneers R | 1993 | Am J Cardiol1993，72，： | 1 |
| 12 | Value of the electrocardiogram in diagnosing the number of severely narrowed coronary arteries in rest angina pectoris显示文摘 | Gorgels APM Vos MA Mulleneers R | 1993 | Am J Cardil1993，72，14： | 1 |
| 13 | Value of the electrocardiogram in diagnosing the number of severely narrowed coronary arteries in rest angina pectoris显示文摘 | Gorgels APM Vos MA Mulleneers R | 1993 | Am J Cardiol1993，72，14： | 1 |
| 14 | Value of the electrocardiogram in diagnosing the number of severely narrowed coronary arteries in rest angina pectoris 显示文摘 | Gorgels AP Vos Ma Mulleneers R | 1993 | Am J Cardiol1993，72，14： | 1 |
| 15 | Acetylation of ezrin regulates membrane–cytoskeleton interaction underlying CCL18-elicited cell migration显示文摘Ezrin,a membrane–cytoskeleton linker protein,plays an essential role in cell polarity establishment,cell migration,and division.Recent studies show that ezrin phosphorylation regulates breast cancer metastasis by promoting cancer cell survivor and promotes intrahepatic metastasis via cell migration.However,it was less characterized whether there are additional post-translational modifications and/or post-translational crosstalks on ezrin underlying context-dependent breast cancer cell migration and invasion.Here we show that ezrin is acetylated by p300/CBP-associated factor(PCAF)in breast cancer cells in response to CCL18 stimulation.Ezrin physically interacts with PCAF and is a cognate substrate of PCAF.The acetylation site of ezrin was mapped by mass spectrometric analyses,and dynamic acetylation of ezrin is essential for CCL18-induced breast cancer cell migration and invasion.Mechanistically,the acetylation reduced the lipid-binding activity of ezrin to ensure a robust and dynamic cycling between the plasma membrane and cytosol in response to CCL18 stimulation.Biochemical analyses show that ezrin acetylation prevents the phosphorylation of Thr567.Using atomic force microscopic measurements,our study revealed that acetylation of ezrin induced its unfolding into a dominant structure,which prevents ezrin phosphorylation at Thr567.Thus,these results present a previously undefined mechanism by which CCL18-elicited crosstalks between the acetylation and phosphorylation on ezrin control breast cancer cell migration and invasion.This suggests that targeting PCAF signaling could be a potential therapeutic strategy for combating hyperactive ezrin-driven cancer progression. | Xiaoyu Song Wanjuan Wang Haowei Wang Xiao Yuan Fengrui Yang Lingli Zhao McKay Mullen Shihao Du Najdat Zohbi Saravanakumar Muthusamy Yalei Cao Jiying Jiang Peng Xia Ping He Mingrui Ding Nerimah Emmett Mingming Ma Quan Wu Hadiyah-Nicole Green Xia Ding Dongmei Wang Fengsong Wang Xing Liu | 2020 | Journal of Molecular Cell Biology2020，12，6： | 1 |
| 16 | An AHP framework for prioritizing customer requirements in QFD:An industrialized housingapplication显示文摘 | ARMACOST R L COMPONATION P J MULLENS MA | 1994 | IIE Transactions1994，26，4： | 1 |
| 17 | Value of the electrocardi- ogram in diagnosing the number of severely narrowed coronary arter- ies in rest angina pectoris 显示文摘 | Gorgels AP Vos MA Mulleneers R | 1993 | Am J Cardiol1993，72，14： | 1 |
| 18 | Value of the electrocardiogram in diagnosing the number of severely narrowed coronary arteries in rest angina pectoris显示文摘 | Gorgels APM Vos MA Mulleneers R | 1993 | Am J Cardiol1993，72，： | 1 |
| 19 | 'IARC group 2B carcinogens'reported in cigarette mainstream smoke显示文摘 | Smith CJ Peffetti TA Mullens MA | 2000 | Food Chem Toxicol2000，38，： | 1 |
| 20 | Insect management in food processing facilities 显示文摘 | Campbell JF Arthur FH Mullen MA | 2004 | Advances in Food & Nutrition Research2004，48，： | 1 |
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