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| 1 | Pravastatin alleviates lipopolysaccharide-induced placental TLR4 over-activation and promotes uterine arteriole remodeling without impairing rat fetal development显示文摘Preeclampsia is associated with over-activation of the innate immune system in the placenta,in which toll-like receptor 4(TLR4) plays an essential part.With their potent anti-inflammatory effects,statins have been suggested as potential prevention or treatment of preeclampsia,although evidence remains inadequate.Herewith,we investigated whether pravastatin could ameliorate preeclampsia-like phenotypes in a previously established lipopolysaccharide(LPS)-induced rat preeclampsia model,through targeting the TLR4/NF-κB pathway.The results showed that pravastatin reduced the blood pressure [maximum decline on gestational day(GD) 12,(101.33±2.49) mmHg vs.(118.3±1.37) mmHg,P<0.05] and urine protein level [maximum decline on GD9,(3,726.23± 1,572.86) μg vs.(1,991.03 ±609.37)μg,P< 0.05],which were elevated following LPS administration.Pravastatin also significantly reduced the rate of fetal growth restriction in LPS-treated rats(34.10% vs.8.99%,P<0.05).Further pathological analyses suggested a restoration of normal spiral artery remodeling in preeclampsia rats by pravastatin treatment.These effects of pravastatin were associated with decreased TLR4/NF-κB protein levels in the placenta and IL-6/MCP-1 levels in serum.Additionally,no obvious abnormalities in fetal liver,brain,and kidney were found after administration of pravastatin.These results provide supportive evidence for use of pravastatin in preventing preeclampsia. | Muyi Yang Zhenyu Diao Zhiyin Wang Guijun Yan Guangfeng Zhao Mingming Zheng Anyi Dai Yimin Dai Yali Hu | 2018 | The Journal of Biomedical Research2018，32，4： | 5 |
| 2 | Ephedrine hydrochloride inhibits PGN-induced inflammatory responses by promoting IL-10 production and decreasing proinflammatory cytokine secretion via the PI3K/Akt/GSK3β pathway显示文摘 | Yuejuan Zheng Yang Yang Yuhu Li Limin Xu Yi Wang Ziyi Guo Haiyan Song Muyi Yang Beier Luo Aoxiang Zheng Ping Li Yan Zhang Guang Ji Yizhi Yu | 2013 | Cellular & Molecular Immunology2013，10，4： | 4 |
| 3 | Single Neuron PID Control Based on Expert Experiences for Temperature Difference Control System of a Digester显示文摘Considering the temperature difference of displacement cooking characterized by severe non-linearity, large time delay, and real-time control, a cascade PID adaptive control strategy composed of a single neuron is proposed to ensure cooking temperature uniformity. The control strategy introduces expert experiences to adjust the single neuron gain K, while a single neuron PID self-learning and adaptive ability, as well as cascade advantage can be combined to realize the real-time and fast temperature difference control. In the Simulink, the s-function of this control strategy is used to carry out a dynamic simulation experiment with temperature difference characteristics and verify the robustness and response to model mismatch. Compared to conventional temperature difference-flow PID cascade control and single neuron PID cascade control, this control strategy has better robustness and stronger adaptability. The results of real-time control on the THJSK-1 experiment platform indicate this control strategy is feasible. | YaNan Huang AiJuan Zhang MuYi Hu | 2017 | Paper And Biomaterials2017，2，1： | 3 |
| 4 | Branched Fluorine/Adamantane Interfacial Compatibilizer for PBO Fibers/Cyanate Ester Wave-Transparent Laminated Composites显示文摘Comprehensive Summary Branched fluorine/adamantane PBO precursor(preFABPBO),synthesized via random co-condensation between 2,2-bis(3-amino-4-hydroxyphenyl)hexafluoro propane,1,3-adamantanedicarbonyl dichloride,and trimesoyl chloride,is performed as interfacial compatibilizer,bisphenol A dicyanate ester(BADCy)resin as polymer matrix,and poly(p-phenylene-2,6-benzobisoxazole)(PBO)fibers as reinforcements to prepare PBO fibers/FABPBO-BADCy wave-transparent laminated composites by high temperature molding.The mechanical properties,wave-transparent performances,and heat resistances of PBO fibers/BADCy composites are simultaneously improved by the addition of preFABPBO.The interlaminar shear strength(ILSS)and flexural strength of PBO fibers/FABPBO-BADCy composites are 48.9 and 665.3 MPa,respectively,increased by 33.2%and 13.3%compared to those of PBO fibers/BADCy composites(36.7 and 587.4 MPa).The dielectric constant and dielectric loss values at 106 Hz are 2.53 and 0.003,respectively,lower than those of PBO fibers/BADCy composites(3.06 and 0.006),and the corresponding wave transmission efficiency is 94.8%,which also presents excellent stability over the wide temperature(25-200℃)and frequency range(103-107 Hz and 8.2-12.4 GHz).Meanwhile,the heat resistance index and glass transition temperature are 229.9℃and 247.5℃,also better than those of PBO fibers/BADCy composites(229.6℃and 247.1℃). | Zheng Liu Xiaoli Fan Muyi Han Hao Li Junliang Zhang Lixin Chen Qiju Zhu Junwei Gu | 2023 | Chinese Journal of Chemistry2023，41，8： | 2 |
| 5 | A study on the vegetation in the east side of Helan Mountain显示文摘 | Jiang Yuan Kang Muyi Liu Shuo Tian Lianshu Lei Mingde | 2000 | Plant Ecology2000，，2： | 1 |
| 6 | Recent progress in the research on using CuSbS_(2) and its derivative CuPbSbS_(3) as absorbers in case of photovoltaic devices显示文摘Thin-film solar cells show considerable application potential as alternative photovoltaic technologies.Cuprous antimony chalcogen materials and their derivatives,represented as CuSbS_(2) and CuPbSbS_(3),respectively,exhibit the advantages of low cost,massive elemental abundance,stability,and good photoelectric properties,including a suitable bandgap and large optical absorption coefficient.These advantages demonstrate that they can be used as light absorbers in photovoltaic applications.In this study,we review the major properties,fabrication methods,and recent progress of the performance of the devices containing CuSbS_(2) and CuPbSbS_(3).Furthermore,the limitations and future development prospects with respect to the CuSbS_(2) and CuPbSbS_(3) solar cells are discussed. | Muyi ZHANG Chong WANG Chao CHEN Jiang TANG | 2021 | Frontiers of Optoelectronics2021，14，4： | 1 |
| 7 | Estrogen induces androgen‐repressed SOX4 expression to promote progression of prostate cancer cells显示文摘 | Muyi Yang Jing Wang Lin Wang Chengwu Shen Bo Su Mei Qi Jing Hu Wei Gao Weiwei Tan Bo Han | 2015 | Prostate2015，，13： | 1 |
| 8 | Reusable sensor based on high magnetization carboxyl-modified graphene oxide with intrinsic hydrogen peroxide catalytic activity for hydrogen peroxide and glucose detection,Biosensors and Bioelectronics显示文摘 | Yang Hungwei Hua Muyi Chen Shilian | 2013 | 41:172-1792013，41，： | 1 |
| 9 | A study on the vegetation in the east side of Helan Mountain显示文摘 | Jiang Yuan Kang Muyi Liu Shuo | 2000 | Plant Ecology2000，149，： | 1 |
| 10 | Plant biodiversity patterns on Helan Mountain,China显示文摘 | JIANG Yuan KANG Muyi ZHU Yuan | 2007 | Acta Oecologica2007，32，2： | 1 |
| 11 | Characterization of EGFR family gene aberrations in cholangiocarcinoma显示文摘 | Xiaoqing Yang Weishan Wang Chunni Wang Lin Wang Muyi Yang Mei Qi Hong Su Xiubin Sun Zhiyan Liu Juan Zhang Xiaomin Qin Bo Han | 2014 | Oncology Reports2014，，2： | 1 |
| 12 | The nature and growth of vertical spe- cialization in world trade显示文摘 | David Hummels Jun Ishii Kei- Muyi | 2001 | Journal of In- ternational Economics2001，，54： | 1 |
| 13 | Assessment for surface water quality in Lake Taihu Tiaoxi River Basin China based on support vector machine显示文摘 | Wei Li Muyi Yang Zhiwei Liang | 2013 | Stochastic Environmental Research and Risk Assessment2013，27，： | 1 |
| 14 | ERG–SOX4 interaction promotes epithelial–mesenchymal transition in prostate cancer cells显示文摘 | Lin Wang Yanjiang Li Xiaoqing Yang Huiqing Yuan Xiangzhi Li Mei Qi Yannicca W.Y. Chang Chunni Wang WeiWei Fu Muyi Yang Juan Zhang Bo Han | 2014 | Prostate2014，，6： | 1 |
| 15 | TRANSFORMATION OF Nd_(14)Fe_(73)Co_6B_7 ALLOY UNDER HYDROGEN TREATMENT显示文摘The phase constitution and variation of Nd14Fe73Co6B7 alloy after hydriding and subsequentdehydriding treatment at 770℃ have been investigated respectively by means of X-raydiffraction,SEM,TEM and magnetic measurement techniques.The original coarse,as castgrain structure,is dissolved into α-Fe,Nd hydride and Fe2B mixture with average dimensionof 0.1 μm,during hydriding process,and subsequently the triphase mixture recombined intofinely unique Nd2Fe14B phase with dimension of 0.3 μm by desorbing the hydrogen.It wasfound that the Nd-rich phase distributed at the boundary of as-cast grain structure diffusedinto matrix Nd2Fe14B grain during hydriding.It remains during dehydriding and distributehomogeneously around some colonies composed of fine grains of Nd2Fe14B. | LIU Jian QIU Baoqin LIU Muyi XIAO Yaofu University of Science and Technology Beijing,Beijing,China associate professor,Department of Materials,University of Science and Technology Beijing,Beijing 100083,China | 1993 | Acta Metallurgica Sinica(English Letters)1993，6，6： | 1 |
| 16 | A large ephemeral release of nitrogen upon wetting of dry soil and corresponding root responses in the field显示文摘 | Muyi Cui Martyn M. Caldwell | 1997 | Plant and Soil1997，，2： | 1 |
| 17 | A study on the vegetation in the east side of Helan Mountain显示文摘 | Jiang Yuan Kang Muyi Liu Shuo | 2000 | Plant Ecology2000，149，： | 1 |
| 18 | Policy entry points forfacilitating a transition towards alow-carbonelectricityfuture显示文摘This study extends the ambit of the debate on electricity transitionby specifically identifying possible policy entry points through which transformative and enduring changes can be made in the electricity and socio-economic systems to facilitate the transition process.Guided by the'essence'of the multi-level perspective-a prominent framework for the study of energy transition,four such entry points have been identified:1)destabilising the dominant,fossil fuel-based electricity regime to create room for renewable technologies tobreak through;2)reconfiguring the electricity regime,which encompasses technology,short-term operational practices and long-term planning processes,to improve flexibility for accommodating large outputs from variable renewable sources whilst maintaining supply security;3)addressing the impactofcoal power phase-outon coal mining regions in terms of economic development and jobs;and 4)facilitating a shift in transition governance towards a learning-based,reflexive process.Specific areas for policy interventions within each of these entry points have also been discussed in the paper. | Muyi YANG Deepak SHARMA Xunpeng SHI | 2022 | Frontiers of Engineering Management2022，9，3： | 0 |
| 19 | Genome-wide characterization of alternative splicing in blood cells of COVID-19 and respiratory infections of relevance显示文摘Dear Editor,Alternative splicing of eukaryotic transcripts refers to the posttranscriptional process in which the coding regions(exons)of a precursor transcript are joined in different combinations through the removal or retention of non-coding intervening sequences(introns)to produce distinct mature messenger RNA(mRNA)transcripts and further generate one or more mature mRNAs(Lee and Rio,2015).Alternative splicing is revealed dysregulation in infectious diseases.Many pathogens hijack the splicing mechanism of host cells to complete their replications,accompanied by dysregulated innate immune response or cell damage,leading to the changes of alternative splicing landscape in host cells(Ashraf et al.,2019;Tomezsko et al.,2020;Kremsdorf et al.,2021).The regulation mechanism of alternative splicing by viral pathogens,such as hepatitis B virus(Duriez et al.,2017),human immunodeficiency virus 1(Tomezsko et al.,2020),Zika virus(Bonenfant et al.,2020)and enterovirus 71(Li et al.,2020),have been explored. | Rui Huang Wenbo Chen Xueya Zhao Yuefei Ma Qiong Zhou Junsen Chen Muyi Zhang Dingran Zhao Yu Hou Chunjiang He Ying Wu | 2023 | Virologica Sinica2023，38，2： | 0 |
| 20 | Broadly neutralizing antibodies derived from the earliest COVID-19 convalescents protect mice from SARS-CoV-2 variants challenge显示文摘Coronavirus disease 2019(COviD-19)was first reported three years ago,when a group of individuals were infected with the original SARS-CoV-2 strain,based on which vaccines were developed.Here,we develop six human monoclonal antibodies(mAbs)from two elite convalescents in Wuhan and show that these mAbs recognize diverse epitopes on the receptor binding domain(RBD)and can inhibit the infection of SARS-CoV-2 original strain and variants of concern(VOCs)to varying degrees,including Omicron strains XBB and XBB. | Qianyun Liu Haiyan Zhao Zhiqiang Li Zhen Zhang Rui Huang Mengxue Gu Ke Zhuang Qing Xiong Xianying Chen Weiyi Yu Shengnan Qian Yuzhen Zhang Xue Tan Muyi Zhang Feiyang Yu Ming Guo Zhixiang Huang Xin Wang Wenjie Xiang Bihao Wu Fanghua Mei Kun Cai Limin Zhou Li Zhou Ying Wu Huan Yan heng Cao Ke Lan Yu Chen | 2023 | Signal Transduction and Targeted Therapy2023，8，10： | 0 |
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