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| 1 | Feasibility and safety of endoscopic submucosal dissection for lower rectal tumors with hemorrhoids显示文摘AIM: To evaluate the feasibility and safety of endoscopic submucosal dissection(ESD) for lower rectal lesions with hemorrhoids.METHODS: The outcome of ESD for 23 lesions with hemorrhoids(hemorrhoid group) was compared with that of 48 lesions without hemorrhoids extending to the dentate line(non-hemorrhoid group) during the same study period. RESULTS: Median operation times(ranges) in the hemorrhoid and non-hemorrhoid groups were 121(51-390) and 130(28-540) min. The en bloc resection rate and the curative resection rate in the hemorrhoid group were 96% and 83%, and they were 100% and 90% in the non-hemorrhoid group, respectively. In terms of adverse events, perforation and postoperative bleeding did not occur in both groups. In terms of the clinical course of hemorrhoids after ESD, the rate of complete recovery of hemorrhoids after ESD in lesions with resection of more than 90% was significantly higher than that in lesions with resection of less than 90%.CONCLUSION: ESD on lower rectal lesions with hemorrhoids could be performed safely, similarly to that on rectal lesions extending to the dentate line without hemorrhoids. In addition, all hemorrhoids after ESD improved to various degrees, depending on the resection range. | Shinwa Tanaka Takashi Toyonaga Yoshinori Morita Namiko Hoshi Tsukasa Ishida Yoshiko Ohara Tetsuya Yoshizaki Fumiaki Kawara Eiji Umegaki Takeshi Azuma | 2016 | World Journal of Gastroenterology2016，22，27： | 6 |
| 2 | Gastric plexiform fibromyxoma resected by endoscopic submucosal dissection after observation of chronological changes:A case report显示文摘A 66-year-old man was diagnosed with a gastric submucosal tumor. Endoscopic ultrasound(EUS) revealed an iso/hypoechoic mass in the third layer. No malignant cells were detected in a histological examination. Yearly follow-up endoscopy and EUS showed the slow growth of the tumor. Endoscopic submucosal dissection(ESD) was performed and a glistening tumor was resected. The lesion showed a multinodular plexiform growth pattern consisting of spindle cells with an abundant fibromyxoid stroma that was rich in small vessels. The tumor was diagnosed as plexiform fibromyxoma(PF) by immunohistochemistry. Although difficulties are associated with reaching a diagnosis preoperatively, chronological changes on EUS may contribute to the diagnosis of PF. ESD may also be useful in the diagnosis and treatment of PF. | Fumiaki Kawara Shinwa Tanaka Takashi Yamasaki Yoshinori Morita Yoshiko Ohara Yoshihiro Okabe Namiko Hoshi Takashi Toyonaga Eiji Umegaki Hiroshi Yokozaki Takanori Hirose Takeshi Azuma | 2017 | World Journal of Gastrointestinal Oncology2017，9，6： | 3 |
| 3 | Distribution of HBV genotypes among HBV carriers in Benin:phylogenetic analysis and virological characteristics of HBV genotype E显示文摘AIM: To determine the distribution of Hepatitis B virus (HBV) genotypes in Benin, and to clarify the virological characteristics of the dominant genotype.METHODS: Among 500 blood donors in Benin, 21 HBsAg-positive donors were enrolled in the study. HBV genotypes were determined by enzyme immunoassay and restriction fragment length polymorphism. Complete genome sequences were determined by PCR and direct sequencing.RESULTS: HBV genotype E (HBV/E) was detected in 20/21 (95.2%), and HBV/A in 1/21 (4.8%). From the age-specific prevalence of HBeAg to anti-HBe seroconversion (SC) in 19 HBV/E subjects, SC was estimated to occur frequently in late teens in HBV/E.The comparison of four complete HBV/E genomes from HBeAg-positive subjects in this study and five HBV/E sequences recruited from the database revealed that HBV/E was distributed throughout West Africa with very low genetic divers ity (nucleotide homology 96.7-99.2%).Based on the sequences in the basic core promoter (BCP)to precore region of the nine HBV/E isolates compared to those of the other genotypes, a nucleotide substitution in the BCP, G1757A, was observed in HBV/E.CONCLUSION: HBV/E is predominant in the Republic of Benin, and SC is estimated to occur in late teens in HBV/E. The specific nucleotide substitution G1757A in BCP, which might influence the virological characteristics,is observed in HBV/E. | Kei Fujiwara Yasuhito Tanaka Etsuro Orito Tomoyoshi Ohno Takanobu Kato Kanji Sugihara Izumi Hasegawa Mayumi Sakurai Kiyoaki Ito Atsushi Ozasa Yuko Sakamoto Isao Arita Ahmed El-Gohary Agossou Benoit Sophie I Ogoundele-Akplogan Namiko Yoshihara Ryuzo Ueda Masashi Mizokami | 2005 | World Journal of Gastroenterology2005，11，41： | 3 |
| 4 | Esophageal diverticulum exposed during endoscopic submucosal dissection of superficial cancer显示文摘Endoscopic submucosal dissection(ESD) is now widely accepted as a strategy to treat superficial esophageal neoplasms.The rate of adverse events,such as perforation,has been decreasing with the improvement of devices and techniques.In this paper,we report a case of esophageal cancer that had a diverticulum under cancerous epithelium.The diverticulum was not detected during preoperative examination,and led to perforation during the ESD procedure.Our case shows that,although rare,some diverticula can exist underneath the mucosal surface without obvious depression.If there is any sign of hidden diverticula during ESD,surgeons should proceed with caution or,depending on the case,the procedure should be discontinued to avoid adverse events. | Shinwa Tanaka Takashi Toyonaga Yoshiko Ohara Tetsuya Yoshizaki Fumiaki Kawara Tsukasa Ishida Namiko Hoshi Yoshinori Morita Takeshi Azuma | 2015 | World Journal of Gastroenterology2015，21，10： | 2 |
| 5 | Bone marrow stromal cells infused into the cerebrospinal fluid promote functional recovery of the injured rat spinal cord with reduced cavity formation显示文摘 | Masayoshi Ohta Yoshihisa Suzuki Toru Noda Yoko Ejiri Mari Dezawa Kazuya Kataoka Hirotomi Chou Namiko Ishikawa Naoya Matsumoto Yasushi Iwashita Eiji Mizuta Sadako Kuno Chizuka Ide | 2004 | Experimental Neurology2004，，2： | 2 |
| 6 | Effects of skin pressure by clothing on digestion and orocecal transit time of food显示文摘 | Yoshiaki S Namiko K Yukimi K | 2000 | Journal of Physiological Anthropology and Applied Human Science2000，19，3： | 1 |
| 7 | Thermal Con- duction in Aligned Carbon Nanotube Polymer Nanocom- posites With High Packing Density 显示文摘 | M Amy Marconnet Namiko Yamamoto | 2011 | ACS NANO2011，5，64： | 1 |
| 8 | Feasibility and Safety of Endoscopic Submucosal Dissection for Large Colorectal Tumors显示文摘 | Shinwa Tanaka Takashi Toyonaga Yoshinori Morita Namiko Hoshi Tsukasa Ishida Yoshiko Ohara Tetsuya Yoshizaki Fumiaki Kawara Takeshi Azuma | 2015 | Surgical Laparoscopy, Endoscopy & Percutaneous Techniques2015，，3： | 1 |
| 9 | Specific recognition of cytosolic thymidine kinase in the human lung tumor by moncelonal antibodies raised against recombi- nant human thymidine kinase显示文摘 | Namiko Kuroiwa Masao Nakayama Tamotsu Fukuda | 2001 | Journal of Immunological Methods2001，253，12： | 1 |
| 10 | Specific recognition of cytosolic thymidine kinase in the human lung tumor by monoclonal antibodies raised against recombinant human thymidine kinase显示文摘 | Namiko Kuroiwa Masao Nakayama Tamotsu Fukuda Hideo Fukui Hidemi Ohwada Takaki Hiwasa Shinji Fujimura | 2001 | Journal of Immunological Methods2001，，： | 1 |
| 11 | Nerve injury signaling显示文摘 | Namiko A Valeria C | 2008 | Curr Opin Neurobiol2008，18，3： | 1 |
| 12 | A trehalose metabolic enzyme controls inflorescence architecture in maize显示文摘 | Namiko Satoh-Nagasawal Nobuhiro Nagasawa Simon Malcomber | 2005 | Nature2005，441，11： | 1 |
| 13 | A single recessive gene controls cadmium translocation in the cadmium hyperaccumulating rice cultivar Cho-Ko-Koku显示文摘 | Kouichi Tezuka Hidenori Miyadate Kazunao Katou Ikuko Kodama Shinichi Matsumoto Tomohiko Kawamoto Satoshi Masaki Hideki Satoh Masayuki Yamaguchi Kenji Sakurai Hidekazu Takahashi Namiko Satoh-Nagasawa Akio Watanabe Tatsuhito Fujimura Hiromori Akagi | | 0，2010，： | 1 |
| 14 | Metastatic ovarian tumors: a review of 64 cases显示文摘 | Namiko Yada-Hashimoto Toshiya Yamamoto Shoji Kamiura Hozumi Seino Hiroki Ohira Keisuke Sawai Tadashi Kimura Fumitaka Saji | 2003 | Gynecologic Oncology2003，，2： | 1 |
| 15 | Causal Relationship between the Loss of RUNX3 Expression and Gastric Cancer显示文摘 | Qing-Lin Li Kosei Ito Chohei Sakakura Hiroshi Fukamachi Ken-ichi Inoue Xin-Zi Chi Kwang-Youl Lee Shintaro Nomura Chang-Woo Lee Sang-Bae Han Hwan-Mook Kim Wun-Jae Kim Hiromitsu Yamamoto Namiko Yamashita Takashi Yano Toshio Ikeda Shigeyoshi Itohara Johji In | 2002 | Cell2002，，： | 1 |
| 16 | Electrical and thermal property enhancement of fiber-reinforced polymer laminate composites through controlled implementation of multi-walled carbon nanotubes显示文摘 | Namiko Yamamoto Roberto Guzman de Villoria Brian L. Wardle | 2012 | Composites Science and Technology2012，，16： | 1 |
| 17 | Specific recognition of cytosolic thymidine kinase in the hu- man lung tumor by monoelonal antibodies raised against re- combinant human thymidine kinase显示文摘 | Namiko Kuroiwa Masao Nakayama Tamotsu Fukuda | 2001 | Journal of Immuno- logical Methods2001，253，12： | 1 |
| 18 | Inhibition of DNA adduct formation and mutagenic action of 3 - amino - 1 - methyl - 5H-pyrido indole by chorophyllin- chitosan in rps Ltransgenic mice显示文摘 | Nobuhiro Takehiro Namiko | 2001 | Jpn J Cancer Res2001，92，8： | 1 |
| 19 | Endoscopic treatment of intracerebral hemorrhage with massive ventricular hemorrhage显示文摘 | TomofumiN Namiko T AtsuhitoM | 2004 | International Congress Series2004，1259，4： | 1 |
| 20 | Inhibition of DNA adduct formation and mutagenic action of 3-amino-1- methyl-5H-pyrido indole by chorophyllin-chitosan in rps L transgenic mice显示文摘 | Nobuhiro Takehiro Namiko | 2001 | Jpn J Cancer Res2001，92，8： | 1 |
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