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| 1 | Crohn's disease in Japanese is associated with a SNP-haplotype of N-acetyltransferase 2 gene显示文摘AIM: To investigate the frequency and distribution of N-acetyltransferase 2 (NAT2) and uridine 5′-diphosphate (UDP)-glucuronosyltransferase 1A7 (UGT1A7) genes in patients with ulcerative colitis (UC) and Crohn's disease (CD).METHODS: Frequencies and distributions of NAT2 and UGT1A7SNPs as well as their haplotypes were investigated in 95 patients with UC, 60 patients with CD, and 200gender-matched, unrelated, healthy, control volunteers by PCR-restriction fragment length polymorphism (RFLP),PCR-denaturing high-performance liquid chromatography (DHPLC), and direct DNA sequencing.RESULTS: Multiple logistic regression analysis revealed that the frequency of haplotype, NAT2*7B, significantly increased in CD patients, compared to that in controls (P= 0.0130, OR = 2.802, 95%CI = 1.243-6.316). However,there was no association between NAT2 haplotypes and UC, or between any UGT1A7haplotypes and inflammatory bowel disease (IBD).CONCLUSION: It is likely that the NAT2 gene is one of the determinants for CD in Japanese. Alternatively, a new CD determinant may exist in the 8p22 region, whereNAT2is located. | Haruhisa Machida Kazuhiro Tsukamoto Chun-Yang Wen Saburou Shikuwa Hajime Isomoto Yohei Mizuta Fuminao Takeshima Kunihiko Murase Naomichi Matsumoto Ikuo Murata Shigeru Kohno Chen-Yang Wen | 2005 | World Journal of Gastroenterology2005，11，31： | 3 |
| 2 | Effects of nitrogen in coated fertilizers on field vegetables 显示文摘 | MASATOSHI O NAOMICHI M SUSUMU H | 1999 | Hokkaido J Agri Exp Farm1999，76，： | 1 |
| 3 | Rapid detection of gene mutations responsible for non-syndromic aortic aneurysm and dissection using two different methods: resequencing microarray technology and next-generation sequencing显示文摘 | Haruya Sakai Shinichi Suzuki Takeshi Mizuguchi Kiyotaka Imoto Yuki Yamashita Hiroshi Doi Masakazu Kikuchi Yoshinori Tsurusaki Hirotomo Saitsu Noriko Miyake Munetaka Masuda Naomichi Matsumoto | 2012 | Human Genetics2012，，4： | 1 |
| 4 | Generation of human bipedal locomo- tion by a bio-nfimetic neuro-musculo-skeletal systen显示文摘 | Naomichi Ogihara Naomichi Ogihara Nobutoshi Yamazaki | 2001 | Biological Cybernetics2001，84，： | 1 |
| 5 | Hyper-accumulation of astaxanthin in a green algaHaematococcus pluvialis at elevated temperatures显示文摘 | Agus Eko Tjahjono Yachiyo Hayama Toshihide Kakizono Yoshio Terada Naomichi Nishio Shiro Nagai | 1994 | Biotechnology Letters1994，，2： | 1 |
| 6 | Boron Removal in Molten Silicon by a Steam -Added Plasma Melting Method显示文摘 | Naomichi Nakamura Hiroyuki Baba Yasuhiko Sakaguchil | 2004 | Materials Transactions2004，45，3： | 1 |
| 7 | Isolation and characterization of compactin resistant mutants of an astaxanthin synthesizing green alga Haematococcus pluvialis显示文摘 | Namthip Chumpolkulwong Toshihide Kakizono Takashi Handa Naomichi Nishio | 1997 | Biotechnology Letters1997，，3： | 1 |
| 8 | A novel methodology to evaluate health impacts caused by VOC exposures using real-time VOC and Holter monitors显示文摘 | Atsushi M Kazukiyo K Naomichi Y | 2010 | InternationalJournal of Environmental Research and Public Health2010，7，： | 1 |
| 9 | The Mechanism of the Alkaline Fusion of Benzenesulfonic Acid显示文摘 | SHIGERU O NAOMICHI F MASAHIRO K | 1966 | Bulletin of the Chemical Society of Japan1966，9，6： | 1 |
| 10 | Application of Immobilized Nitrifiers Get to Removal of High Ammonium Nitrogen 显示文摘 | Kazuhiro T Masakazu N Naomichi M | 1994 | Wat Sci Tech1994，29，9： | 1 |
| 11 | Triangular arbitrage in the foreign exchange market 显示文摘 | Aiba Yukihiro and Hatano Naomichi | 2004 | Physiea A2004，344，： | 1 |
| 12 | A microscopic model of triangular arbitrage 显示文摘 | Aiba Yukihiro and Hatano Naomichi | 2006 | Physica A2006，371，2： | 1 |
| 13 | Influence of redox potential on biomethanation of H2 and CO2 by methanobacterium thermoautotrophicum in Eh-Stat batch cultures显示文摘 | HAE SUNG JEE NISHIO NAOMICHI NAGAI SHI RO | 1987 | Journal of General Applied and Microbiology1987，33，5： | 1 |
| 14 | Recent progress in genetics of Marfan syndrome and Marfan-associated disorders显示文摘 | Takeshi Mizuguchi Naomichi Matsumoto | 2007 | Journal of Human Genetics2007，，1： | 1 |
| 15 | Role of endothelin-1 induced by insulin in the regulation of vascular cell growth显示文摘 | Michiko Nagai Kei Kamide Hiromi Rakugi Shin Takiuchi Michio Imai Iwao Kida Naomichi Matsukawa Jitsuo Higaki Toshio Ogihara | 2003 | American Journal of Hypertension2003，，3： | 1 |
| 16 | Neuropathology of leukoencephalopathy with brainstem and spinal cord involvement and high lactate caused by a homozygous mutation of DARS2显示文摘 | Sumimasa Yamashita Noriko Miyake Naomichi Matsumoto Hitoshi Osaka Mizue Iai Noriko Aida Yukichi Tanaka | 2012 | Brain and Development2012，，： | 1 |
| 17 | Matrix extracellular phosphoglycoprotein (MEPE) is highly expressed in osteocytes in human bone显示文摘 | Akihide Nampei Jun Hashimoto Kenji Hayashida Hideki Tsuboi Kenrin Shi Isamu Tsuji Hideaki Miyashita Takao Yamada Naomichi Matsukawa Masayuki Matsumoto Shigeto Morimoto Toshio Ogihara Takahiro Ochi Hideki Yoshikawa | 2004 | Journal of Bone and Mineral Metabolism2004，，3： | 1 |
| 18 | Anti-oxidative effect of Klotho on endothelial cells through cAMP activation显示文摘 | Hiromi Rakugi Naomichi Matsukawa Kazuhiko Ishikawa Jin Yang Michio Imai Masashi Ikushima Yoshihiro Maekawa Iwao Kida Jun-ichi Miyazaki Toshio Ogihara | 2007 | Endocrine2007，，1： | 1 |
| 19 | Inhibition of the Fermentation of Propionate to Methane by Hydrogen, Acetate, and Propionate 显示文摘 | Staoshi Fukuzaki Naomichi Nisshio Manabu Shobayashi Shiro Nagai | 1990 | Applied AND Environmental Microbiology1990，56，3： | 1 |
| 20 | Effects of nitrogen in coated fertilizers on field vegetables显示文摘 | Masatoshi O Naomichi M Susumu H | 1999 | Hokkaido Journal of Agricultural Experiment Farm1999，76，： | 1 |
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