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| 1 | Ocular complications of diabetes mellitus显示文摘Diabetes mellitus(DM) is a important health problem that induces ernestful complications and it causes significant morbidity owing to specific microvascular complications such as, retinopathy, nephropathy and neuropathy, and macrovascular complications such as, ischaemic heart disease, and peripheral vasculopathy. It can affect children, young people and adults and isbecoming more common. Ocular complications associated with DM are progressive and rapidly becoming the world's most significant cause of morbidity and are preventable with early detection and timely treatment. This review provides an overview of five main ocular complications associated with DM, diabetic retinopathy and papillopathy, cataract, glaucoma, and ocular surface diseases. | Nihat Sayin Necip Kara G?khan Pekel | 2015 | World Journal of Diabetes2015，6，1： | 38 |
| 2 | Blunt trauma related chest wall and pulmonary injuries: An overview显示文摘Physical traumas are tragic and multifaceted injuries that suddenly threaten life.Although it is the third most common cause of death in all age groups,one out of four trauma patients die due to thoracic injury or its complications.Blunt injuries constitute the majority of chest trauma.This indicates the im porta nee of chest trauma among all traumas.Blunt chest trauma is usually caused by motor vehicle accident,falling from height,blunt instrument injury and physical assault.As a result of chest trauma,many injuries may occur,such as pulm onary injuries,and these require urge nt in terve ntion.Chest wall and pulmonary injuries range from rib fractures to flail chest,pneumothorax to hemothorax and pulmonary contusion to tracheobronchial injuries.Following these injuries,patients may present with a simple dyspnea or even respiratory arrest.For such patie nt,it is imports nt to understa nd the treatme nt logic and to take a multidisciplinary approach to treat the pulmonary and chest wall injuries.This is because only 10%of thoracic trauma patients require surgical operation and the remaining 90%can be treated with simple methods such as appropriate airway,oxygen support,maneuvers,volume support and tube thoracostomy.Adequate pain control in chest trauma is sometimes the most basic and best treatment.With definite diagnosis,the morbidity and mortality can be significantly reduced by simple treatment methods. | Bekir Nihat Dogrul Ibrahim Kiliccalan Ekrem Samet Asci Selim Can Peker | 2020 | Chinese Journal of Traumatology2020，23，3： | 19 |
| 3 | 【原创论文】同侧和对侧大鼠睾丸缺血再灌注损伤的生化效应和褪黑激素对此的保护作用显示文摘睾丸扭转(TT),是一个多发于青春期男性的泌尿急症,如果不及时治疗,可致不孕不育。睾丸扭转所致缺血再灌注(I/R)损伤在睾丸损伤的病理生理过程中起一定作用。我们研究了褪黑激素在单侧睾丸扭转大鼠中同侧和对侧睾丸的氧化损伤效应:将21只青春期雄性Wistar大鼠分成三组,每组七只,处理如下:第1组(假手术组):行左睾丸和双边睾丸假切除术;第2组(I/R组):通过以下方式诱发缺血再灌注损伤(顺时针720°旋转左侧睾丸2小时,2小时后复位):第3组(I/R+MEL组):大鼠经诱导缺血再灌注损伤和一次性褪黑激素注射(50mgkg-1,i.p)。处理后离体分离各组大鼠双侧睾丸,用于检测睾丸组织中抗氧化过氧化氢酶、超氧化物歧化酶和谷胱甘肽过氧化物酶的活性,丙二醛、蛋白质羰基和一氧化氮的组织水平。较对照组,褪黑激素注射组同侧睾丸的脂质过氧化水平,相关酶活性降低,具有显著性(P〈0.05),而在对侧的睾丸中相关酶活性变化无统计学意义(P〉0.05)。在对侧睾丸中,丙二醛水平改变具有明显统计学意义(P=0.009)。应用褪黑素能减轻老鼠同侧睾丸扭转所致缺血再灌注损伤的不利影响,而对于对侧睾丸,睾丸扭转影响不大。 | Bekir S Parlaktas Dogan Atilgan Huseyin Ozyurt Yusuf Gencten Ali Akbas Fikret Erdemir Nihat Uluocak | 2014 | Asian Journal of Andrology2014，16，2： | 10 |
| 4 | Effects of the myeloperoxidase 463 gene polymorphisms on development of atrophy in H pylori infected or noninfected gastroduodenal disease显示文摘AIM: To investigate the relationship between myelo- peroxidase polymorphisms as a host-related factor and atrophy caused by H pylori. METHODS: Our study enrolled 77 patients. Biopsy materials obtained during gastrointestinal endoscopies were evaluated for the presence of H pylori. Polymerase chain reaction-restriction fragment length polymorphism assay was used to characterize myeloperoxidase genotypes. RESULTS: Forty four patients (57.1%) were Hp (+) and 33 (42.9%) were Hp (-). Sixty six (85.7%) had GG genotype, 10 (12.9%) had GA genotype and 1 (1.29%) had AA genotype. The change in atrophy in relation to neutrophil infiltration was significant in Hp (+) patients (P = 0.0001). The change in atrophy in relation to neutrophil infiltration in patients with GG genotype was significant (P = 0.002). However, the change in atrophy in relation to neutrophil infiltration was not significiant in patients with Hp (+) GG genotype (r = 0.066, P = 0.63). CONCLUSION: Myeloperoxidase genotype is critical for development of atrophy in relation to the severity of inflammation. However, it is interesting to note that, H pylori does not show any additive effect on development of atrophy. | mer Yilmaz Hakan Dursun Nesrin Gürsan ibrahim Pirim Arif Yilmaz Nihat Okcu | 2007 | World Journal of Gastroenterology2007，13，8： | 6 |
| 5 | Vasospastic myocardial infarction:An even rarer occurrence of a rare entity显示文摘INTRODUCTION Vasospastic angina(VSA)is an important functional cardiac disorder that leads to transient myocardial ischemia and is caused by sudden,intense and reversible coronary artery spasm resulting in subtotal or total occlusion.[1,2]VSA is associated with cardiac conditions such as stable or unstable angina,acute coronary syndromes and lethal arrhythmias.The patients | Cem Ertan Mehmet Emre Ozpelit Onder Limon Dcniz Oray Nihat Pekel | 2017 | World Journal of Emergency Medicine2017，8，1： | 4 |
| 6 | Anti-pancreatic antibody in Turkish patients with inflammatory bowel disease and first-degree relatives显示文摘AIM: To identify the role of anti-pancreatic antibody (PAB) in the diagnosis of inflammatory bowel diseases (IBD) among Turkish patients, and its frequency in firstdegree relatives.METHODS: PAB and anti-Saccharomyces cerevisiae (ASCA) were examined in serum samples of 214 subjects including patients with Crohn's disease (CD, n = 64), ulcerative colitis (UC, n = 63), first-degree relatives of patients with CD (n = 25), first-degree relatives of patients with UC (n = 28),and a control group with gastrointestinal symptoms other than (IBD) (n = 34) by indirect immunofluorescence Positivity of PAB and ASCA was compared in terms of Vienna classification, disease activity and medications used.RESULTS: In terms of PAB positivity, no difference was found between patients with CD (14.1%) and UC (7.9%) however, significant difference was observed between patients with CD and subjects in the control group (P < 0.05). No difference was found between patients with CD and their relatives in terms of ASCA positivity, whereas a significant difference was found between other groups (P < 0.001). Compared to ASCA, the sensitivity of the PAB was 19% (7/37), its specificity was 93% (25/27), positive predictive value was 77% (7/9) and negative predictive value was 45% (25/55). ASCA was found with significantly higher prevalence in patients with CD activity index > 150 (P < 0.05).CONCLUSION: PAB is valuable in the diagnosis of IBD rather than CD, but cannot be used alone for diagnostic purposes. PAB is not superior to ASCA in CD diagnosis and in detecting CD among relatives of patients with CD. | Huseyin Demirsoy Kamil Ozdil Ozdal Ersoy Besir Kesici Cetin Karaca Canan Alkim Nihat Akbayir Levent Kamil Erdem Mehmet Derya Onuk Hulya Tugrul Beyzadeoglu | 2010 | World Journal of Gastroenterology2010，16，45： | 3 |
| 7 | Airborne Pollen Grains Of Afyon, Turkey显示文摘The airborne pollen grains of Afyon have been studied for a two_year period (1999-2000) with a Durham sampler. A total of 14 367 pollen grains belonging to 40 taxa have been identified and recorded with some unidentified ones. Of them, 6 732 were identified in 1999 and 7 635 in 2000. Of the total pollen grains, 69.67% were arboreal, 26.64% non_arboreal and 3.68 % unidentified. The majority of the investigated pollen grains were from Pinus, Gramineae, Cupressaceae, Platanus , Chenopodiaceae/Amaranthaceae, Quercus, Ailanthus, Moraceae, Juglans , Salix, Cedrus and Rosaceae. The highest level of pollen grains was in May. | Adem BICAKCI 1, Süheyla ERGUN 2, Sevcan TATLIDIL 1, Hulusi MALYER 1, Sabri ?ZYURT 2, Ahmet AKKAYA 3, Nihat SAPAN 5 Department of Biology, Faculty of Science, University of Uludag, Bursa, Turkey 2. Department of Biology, Faculty of Science, University of Afyon Kocatepe, Afyon Turkey 3. Department of Pulmonology, Faculty of Medicine, University of Süleyman Demirel, Isparta, Turkey 4. Division of Pediatric Allergy, Faculty of Medicine, University of Uludag, Bursa, Turkey) | 2002 | Acta Botanica Sinica2002，44，11： | 3 |
| 8 | Prevalence of microscopic colitis in patients with diarrhea of unknown etiology in Turkey显示文摘AIM: To investigate the prevalence and demography of microscopic colitis in patients with diarrhea of unknown etiology and normal colonoscopy in Turkey. METHODS: Between March, 1998 to July, 2005, 129 patients with chronic non-bloody diarrhea of unexplained etiology who had undergone full colonoscopy with no obvious abnormalities were included in the study. Two biopsies were obtained from all colonic segments and terminal ileum for diagnosis of microscopic colitis. On histopathologic examination, criteria for lymphocytic colitis (intraepithelial lymphocyte ≥ 20 per 100 intercryptal epithelial cells, change in surface epithelium, mononuclear infiltration of the lamina propria) and collagenous colitis (subepithelial collagen band thickness ≥ 10 μm) were explored. RESULTS: Lymphocytic colitis was diagnosed in 12 (9%) patients (Female/Male: 7/5, mean age: 45 year, range: 27-63) and collagenous colitis was diagnosed in only 3 (2.5%) patients (all female, mean age: 60 years, range: 54-65).CONCLUSION: Biopsy of Turkish patients with the diagnosis of chronic non-bloody diarrhea of unexplained etiology and normal colonoscopic findings will reveal microscopic colitis in approximately 10% of the patients. Lymphocytic colitis is 4 times more frequent than collagenous colitis in these patients. | Levent Erdem Sadιk Yιldιrιm Nihat Akbayιr Banu Yιlmaz Necati Yenice Orhan Sami Gültekin nder Peker | 2008 | World Journal of Gastroenterology2008，14，27： | 2 |
| 9 | Platelet activation and inflammatory response in patients with non-dipper hypertension显示文摘 | Mehmet Gungor Kaya Mikail Yarlioglues Ozgur Gunebakmaz Ertugrul Gunturk Tugrul Inanc Ali Dogan Nihat Kalay Ramazan Topsakal | 2009 | Atherosclerosis2009，，1： | 2 |
| 10 | Remote Control of an Ultrasonic Mo- tor by Using a GSM Mobile Phone显示文摘 | Erdal B Nihat D | 2005 | Sensors and Ac- tuators A : Physical2005，120，2： | 1 |
| 11 | Oxidative stress in portal hypertension-induced rats with particular emphasis on nitric oxide and trace metals显示文摘AIM: To investigate the oxidative-stress-related changes in rats with portal hypertension with particular emphasis on nitric oxide (NO) and trace metals. METHODS: Cirrhosis was induced by partial portal vein ligation (PVL) in Wistar rats. The lipid peroxidation marker (malondialdehyde, MDA), antioxidant defense enzymes including superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), and agents known to have antioxidant features including nitric oxide (NO), zinc (Zn), copper (Cu) were determined both in serum and in liver tissue at 4 wk after surgery in PVL and sham-operated rats. Portal pressure of all experimental animals was measured. MDA was detected by thiobarbituric acid reactivity assay.SOD activity was determined by inhibition of nitroblue tetrazolium reduction with xanthine/xanthine oxidase used asa superoxide generator. CAT activity was determined by the breakdown of hydrogen peroxide. GSH concentrations were measured by using metaphosphoric acid for protein precipitation and 5'-5'-dithio-bis-2-nitrobenzoic acid for color development. NO was detected by the Griess method after reduction of nitrate to nitrite with nitrate reductase, and the concentrations of Zn and Cu were measured by a Shimadzu 680 AA atomic absorption spectrometer. Histopathological confirmation was done under light microscope. Statistical analyses were done by Student's t-test, and significance of the difference was tested by the unpaired Mann-Whitney test. P<0.05 was considered statistically significant.RESULTS: Histopathological studies confirmed PVL induced cirrhotic changes. There was a statistically significant difference in portal pressure between PVL and control groups (P<0.001). The results showed significant increases in the levels of MDA and NO in both tissue and serum (P<0.05 and P<0.001, respectively in tissue; P<0.001 for each in serum), and Zn only in tissue (P<0.001)in rats with PVL compared with sham-operated rats. Besides, PVL rats exhibited reduced plasma and tissue GSH, CAT, SOD (P<0.001 for each). Serum and tissue Cu concentration did not change.CONCLUSION: Our findings suggest that PVL in rats induces important biochemical and molecular changes related to oxidative stress in the liver. | Titiz Izzet Krand Osman Unal Ethem Yavuz Nihat Kusaslan Ramazan Dogan Mustafa Uzun Hafize Kiziler Ali Riza Aydemir Birsen Genc Habibe Aydin Seval Simsek Gonul | 2005 | World Journal of Gastroenterology2005，11，23： | 1 |
| 12 | A study on kerr and material removal rate in wire electrical discharge machining based on taguchi method 显示文摘 | Tosun Nihat Cogun Can Tosun Gul | 2004 | Journal of Materials Processing Technology2004，152，： | 1 |
| 13 | Investigation of optical band gap and device parameters of rubrene thin film prepared using spin coating technique 显示文摘 | Nihat Tug luog lu Behzad Boris Hatice Gurel | 2014 | Journal of Alloys and Compounds2014，582，： | 1 |
| 14 | The assessment of atheros - clerosis on vascular structures in patients with acute coronary syndrome显示文摘 | Nihat K Mikail Y Idris A | 2010 | Clin Invest Med2010，33，1： | 1 |
| 15 | Initiated chemical vapor deposition of pH responsive poly (2-diisopropylamino)ethyl methacrylate thin films显示文摘 | Mustafa Karamana Nihat Cabuk | 2012 | Thin Solid Films2012，512，21： | 1 |
| 16 | Thermo-physical properties of concrete exposed to high temperature显示文摘 | Ahmet B. Kizilkanat Nabi Yüzer Nihat Kabay | 2013 | Construction and Building Materials2013，，： | 1 |
| 17 | Quantity discounts under demand uncertainty显示文摘 | Nihat Altintas Feryal Erhun Sridhar Tayur | 2008 | Management Science2008，54，4： | 1 |
| 18 | Discharging capacity of rectangular side weirs in straight open channels 显示文摘 | M Emin Emiroglu Hayrullah Agaccioglu Nihat Kaya | 2011 | Flow Measurement and Instrumen- tation2011，22，： | 1 |
| 19 | Coronary heart disease is associated with mean platelet volume in type 2 diabetic patients显示文摘 | Yusuf Tavil Nihat Sen Hü seyin Yazici Murat Turfan Fatma Hizal Atiye ? engel Adnan Abaci | 2010 | Platelets2010，，5： | 1 |
| 20 | Torque ripple minimization of a switched reluctance motor by using continuous sliding mode control technique显示文摘 | Nihat Inanc Veysel Ozbulur | 2003 | Electric Power Systems Research2003，，3： | 1 |
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