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| 1 | Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study)显示文摘AIM: To establish which scolicidal agents are superiorand more suitable for regular use.METHODS: Echinococcus granulosus protoscoleceswere obtained from 25 patients with liver hydatidcysts. Various concentrations of albendazole sulfone,albendazole sulfoxide, and albendazole sulfone andalbendazole sulfoxide mixed together in concentrationsof 50 μg/mL, and H2O2 in a concentration of 4%, NaCl20%, and 1.5% cetrimide-0.15% chlorhexidine (10%Savlon-Turkey) were used to determine the scolicidaleffects. Albendazole (ABZ) derivatives and otherscolicidal agents were applied to a minimum of 100scoleces for 5 and 10 min. The degree of viability wascalculated according to the number of living scolicesper fi eld from a total of 100 scolices observed underthe microscope.RESULTS: After 5 min, ABZ sulfone was 97.3%effective, ABZ sulfoxide was 98.4% effective, and thecombined solution was 98.6% effective. When sulfone,sulfoxide and the combined solutions were compared,the combined solution seemed more effective thansulfone. However, there was no difference when thecombined solution was compared with sulfoxide. After10 min, hypertonic salt water, sulfone, sulfoxide, andthe combined solution compared to other solutionslooked more effective and this was statisticallysignificant on an advanced level. When sulfone,sulfoxide, and the combined solutions were compared with each other, the combined solution appeared more effective than sulfone. When the combined solution was compared with sulfoxide, there was no difference.CONCLUSION: Despite being active, ABZ metabolites did not provide a marked advantage over 20% hypertonic saline. According to these results, we think creating a newly improved and more active preparation is necessary for hydatid cyst treatment. | Gokhan Adas Soykan Arikan Ozgur Kemik Ali Oner Nilgun Sahip Oguzhan Karatepe | 2009 | World Journal of Gastroenterology2009，15，1： | 19 |
| 2 | Unusual histopathological findings in appendectomy specimens:A retrospective analysis and literature review显示文摘AIM: To document unusual findings in appendectomy specimens. METHODS: The clinicopathological data of 5262 patients who underwent appendectomies for presumed acute appendicitis from January 2006 to October 2010 were reviewed retrospectively. Appendectomies performed as incidental procedures during some other operation were excluded. We focused on 54 patients who had unusual findings in their appendectomy specimens. We conducted a literature review via the PubMed and Google Scholar databases of English language studies published between 2000 and 2010 on unusual findings in appendectomy specimens. RESULTS: Unusual findings were determined in 54 (1%) cases by histopathology. Thirty were male and 24 were female with ages ranging from 15 to 84 years (median, 32.2 ± 15.1 years). Final pathology revealed 37 cases of enterobiasis, five cases of carcinoids, four mucinous cystadenomas, two eosinophilic infiltrations, two mucoceles, two tuberculosis, one goblet-cell carcinoid, and one neurogenic hyperplasia. While 52 patients underwent a standard appendectomy, two patients who were diagnosed with tuberculous appendicitis underwent a right hemicolectomy. All tumors were located at the distal part of the appendix with a mean diameter of 6.8 mm (range, 4-10 mm). All patients with tumors were alive and disease-free during a mean follow-up of 17.8 mo. A review of 1366 cases reported in the English literature is also discussed. CONCLUSION: Although unusual pathological findings are seldom seen during an appendectomy, all appendectomy specimens should be sent for routine histopathological examination. | Sami Akbulut Mahmut Tas Nilgun Sogutcu Zulfu Arikanoglu Murat Basbug Abdullah Ulku Heybet Semur Yusuf Yagmur | 2011 | World Journal of Gastroenterology2011，17，15： | 4 |
| 3 | 西地那非能改善慢性肾功能衰竭大鼠的勃起功能显示文摘勃起功能障碍(ED)和慢性肾衰竭(CRF)之间的关系已在几个研究中被报道。本研究旨在探讨长期使用西地那非是否能增强CRF诱导大鼠的勃起能力。此外,我们评估了该治疗对某些分子的影响,这些分子被认为在勃起生理学及CRF相关的ED中起关键作用。研究分三组:(1)年龄配对的对照组,(2)CRF诱导的大鼠模型组,(3)CRF诱导大鼠给予西地那非慢性给药组((5 mg /kg口服6周[CRF诱导后6周开始治疗])。 3个月时,所有的动物进行海绵体神经刺激(CNS)来评估勃起功能。在所有大鼠组进行,阴茎组织晚期糖化终产物(AGE的) / 5-羟甲基-2-糠醛,丙二醛(MDA),cGMP(ELISA),诱导型一氧化氮合酶(iNOS)和神经元型NOS(nNOS的)(Western印迹)分析。CRF诱导大鼠与对照组相比,勃起功能有显著降低(P 〈0.05)。CRF诱导大鼠西地那非治疗组(第3组),海绵体内压(ICP)和曲线下面积的
增加量,大于CRF诱导大鼠组(第2组)。此外,西地那非治疗下调了AGE,MDA和iNOS的水平,同时保持了CRF诱导阴茎组织的nNOS和cGMP含量。西地那非治疗组AGE,MDA,iNOS的下降和nNOS,cGMP水平的增加,增加了ICP和海绵体神经刺激(CNS)的总ICP,使得CRF诱导大鼠阴茎勃起功能得到改善。本研究的结果表明慢性西地那非给药对CRF诱导大鼠的勃起功能有治疗效果。 | Nilgun Gurbuz Arif Kol Tumay Ipekci Erhan Ates Asli Baykal Mustafa F Usta | 2015 | Asian Journal of Andrology2015，17，5： | 3 |
| 4 | Hypogonadism and erectile dysfunction: an overview显示文摘在人,雄激素衰落表现为包括减少的性兴趣的一幅临床的图画,减少的可勃起的 capasity,推迟或不在的高潮和减少的性快乐。另外,在心情,是的减少的井,疲劳,消沉和易怒变化也与雄激素不足被联系。在阴茎的发展,生长,和 maintanence 的雄激素的关键角色广泛地被接受了。尽管,可勃起的生理学上的雄激素的准确效果仍然保持未经决定,最近的试验性的研究有关于在雄激素和可勃起的功能之间的关系拓宽我们的理解。现出症状之前的潜的研究证明雄激素剥夺在阴茎的神经结构导致阴茎织物萎缩和改变。而且,雄激素剥夺引起了到包含房间的脂肪的累积并且减少内皮和神经元的氮的氧化物 synthases (eNOS 和 nNOS ) 的蛋白质表示,和磷酸二酯酶 type-5 (PDE-5 ) ,哪个戏在正常的关键角色可勃起的生理学。在最近的文学的光上,我们试图也在阴茎织物和可勃起的生理学的结构,开发和 maintanence 上介绍雄激素的直接效果。Furhermore,根据临床的研究,我们在使人变老结束原因论,病理生理学, prevalance,诊断和性腺机能减退的治疗选择。 | Nilgun Gurbuz Elnur Mammadov Mustafa Faruk Usta | 2008 | Asian Journal of Andrology2008，10，1： | 3 |
| 5 | Post-procedure Elevated Amylase and Lipase Levels After Double-Balloon Enteroscopy: Relations with the Double-Balloon Technique显示文摘 | Cengiz Pata Umit Akyüz Yusuf Erzin Nilgun Mutlu Arzu Mercan Ahmet Dirican | 2010 | Digestive Diseases and Sciences2010，，7： | 3 |
| 6 | Discriminating performance of macular ganglion cellinner plexiform layer thicknesses at different stages of glaucoma显示文摘AIM: To determine the discriminating performance of the macular ganglion cell-inner plexiform layer(GCIPL) parameters between all the consecutive stages of glaucoma(from healthy to moderate-to-severe glaucoma), and to compare it with the discriminating performances of the peripapillary retinal nerve fiber layer(RNFL) parameters and optic nerve head(ONH) parameters.METHODS: Totally 147 eyes(40 healthy, 40 glaucoma suspects, 40 early glaucoma, and 27 moderate-to-severe glaucoma) of 133 subjects were included. Optical coherence tomography(OCT) was obtained using Cirrus HD-OCT 5000. The diagnostic performances of GC-IPL, RNFL, and ONH parameters were evaluated by determining the area under the curve(AUC) of the receiver operating characteristics. RESULTS: All GC-IPL parameters discriminated glaucoma suspect patients from subjects with healthy eyes and moderate-to-severe glaucoma from early glaucoma patients(P<0.017, for all). Also, minimum, inferotemporal and inferonasal GC-IPL parameters discriminated early glaucoma patients from glaucoma suspects, whereas no RNFL or ONH parameter could discriminate between the two. The best parameters to discriminate glaucoma suspects from subjects with healthy eyes were superonasal GC-IPL, superior RNFL and average c/d ratio(AUC=0.746, 0.810 and 0.746, respectively). Discriminating performances of all the parameters for early glaucoma vs glaucoma suspect comparison were lower than that of the other consecutive group comparisons, with the bestGC-IPL parameters being minimum and inferotemporal(AUC=0.669 and 0.662, respectively). Moreover, minimum GC-IPL, average RNFL, and rim area(AUC=0.900, 0.858, 0.768, respectively) were the best parameters for discriminating moderate-to-severe glaucoma patients from early glaucoma patients.CONCLUSION: GC-IPL parameters can discriminate glaucoma suspect patients from subjects with healthy eyes, and also all the consecutive stages of glaucoma from each other(from glaucoma suspect to moderate-tosevere glaucoma). Further, the discriminating performance of GC-IPL thicknesses is comparable to that. | Melih Ustaoglu Nilgun Solmaz Feyza Onder | 2019 | International Journal of Ophthalmology(English edition)2019，12，3： | 2 |
| 7 | Evaluation of 532-nm KTP laser treatment efficacy on acne vulgaris with once and twice weekly applications显示文摘 | Ozlem Yilmaz Nilgun Senturk Esra Pancar Yuksel Fatma Aydin Muge Guler Ozden Tayyar Canturk Ahmetyasar Turanli | 2011 | Journal of Cosmetic and Laser Therapy2011，，6： | 2 |
| 8 | 'Ritual,Tradition and Reconstruction in Contemporary Nigerian Drama:Femi Osofisan and Tess Akaeke Onwueme a Dramatic Analysis in Afrocentricity'显示文摘 | Nilgun | 1999 | Nigerian literature1999，，5： | 1 |
| 9 | Determination of lead, copper and manganese by graphite furnace atomic absorption spectrometry after separation/concentration using a water-soluble polymer 显示文摘 | Nilgun T Suleyman A Cemal O | 2004 | Talanta2004，63，： | 1 |
| 10 | Water quality monitoring network design:A problem of multi-objective decision making显示文摘 | Nilgun B Harmancioglu Necdet Alpaslan | 1992 | Water Resources Bulletin1992，28，1： | 1 |
| 11 | Adsorption of a Non-ionic Dispersant on Lignite Particle Surfaces 显示文摘 | Nilgun K | 2003 | Energy Conversion and Management2003，44，： | 1 |
| 12 | Sulfur dioxide adsorption by activated carbons having different textural and chemical properties显示文摘 | NILGUN K IIKUN O REHA Y | 2008 | Fuel2008，26，6： | 1 |
| 13 | Entropy-based assessment of water quality monitoring networks显示文摘 | Sevinc Ozkul Nilgun B Harmnaciou Vijay P Singh | 2000 | Journal of Hydrologic Engineering2000，5，1： | 1 |
| 14 | Derivative UV Spectrophotometric Method for the Simultaneous Determination of Ambroxol and Preservatives in Syrups显示文摘 | Hasan Basan Zafer Dincer Nilgun Gunden Goger | 2005 | Chem Anal2005，50，2： | 1 |
| 15 | Biodiesel production form waste oils by using lipase immobilized on hydrotaldte and zeolites显示文摘 | FUNDA Y DILEK K NILGUN A | 2007 | Chemical Engineering Journal2007，134，13： | 1 |
| 16 | An illustration of the transport and deposition of mineral dust onto the eastern Mediterranean 显示文摘 | Nilgun K Slobodan N | 2000 | Atmospheric Environment2000，34，： | 1 |
| 17 | Hypertrophic cranial pachymeningitis involving dural sinuses: a pseudo signal-void appearance on MRI显示文摘 | Nilgun Yunten Ismail Oran Cem Calli Mustafa Parildar | 1999 | European Journal of Radiology1999，，3： | 1 |
| 18 | Reduced toxicity and broad spectrum resistance to viral and fungal infection in transgenic plants expressing pokeweed antiviral protein II显示文摘 | Pinger Wang Oleg Zoubenko Nilgun E. Tumer | 1998 | Plant Molecular Biology1998，，6： | 1 |
| 19 | Reproducibility and Tolerability of the ICare Rebound Tonometer in School Children显示文摘 | Afsun Sahin Hikmet Basmak Leyla Niyaz Nilgun Yildirim | 2007 | Journal of Glaucoma2007，，2： | 1 |
| 20 | Investigation of soil multi-element composition in Antalya,Turkey显示文摘 | NILGUN G OMAR A GMDAL T | 2003 | Environ International2003，10，55： | 1 |
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