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| 1 | Association between cag-pathogenicity island in Helicobacter pylori isolates from peptic ulcer,gastric carcinoma,and non-ulcer dyspepsia subjects with histological changes显示文摘AIM: To investigate the presence of the cay-pathogenicity island and the associated histological damage caused by strains with complete cay-PAI and with partial deletions in correlation to the disease status.METHODS: We analyzed the complete cag-PAI of 174representative Helicobacter pylori (H pylori ) clinical isolates obtained from patients with duodenal ulcer,gastric ulcer, gastric cancer, and non-ulcer dyspepsia using eight different oligonucleotide primers viz cagA1,cagA2, cagAP1, cagAP2, cagE, cagT, LEC-1, LEC-2spanning five different loci of the whole cag-PAI by polymerase chain reaction (PCR).RESULTS: The complete screening of the genes comprising the cag-PAI showed that larger proportions of subjects with gastric ulcer (97.8%) inhabited strains with complete cag-PAI, followed by gastric cancer (85.7%),non-ulcer dyspepsia (7.1%), and duodenal ulcer (6.9%),significant differences were found in the percentagedistribution of the genes in all the clinical groups studied.It was found that strains with complete cag-PAI were able to cause severe histological damage than with the partially deleted ones.CONCLUSION: The cay-PAI is a strong virulent marker in the disease pathogenesis as it is shown that a large number of those infected with strain with complete cag-PAI had one or the other of the irreversible gastric pathologies and interestingly 18.5% of them developed gastric carcinoma. The presence of an intact cayPAI correlates with the development of more severe pathology, and such strains were found more frequently in patients with severe gastroduodenal disease. Partial deletions of the cag-PAI appear to be sufficient to render the organism less pathogenic. | Mahaboob Ali Aleem A Khan Santosh K Tiwari Niyaz Ahmed L Venkateswar Rao CM Habibullah | 2005 | World Journal of Gastroenterology2005，11，43： | 15 |
| 2 | Non-invasive assessment of choledocholithiasis in patients with gallstones and abnormal liver function显示文摘AIM:To find a non-invasive strategy for detecting choledocholithiasis before cholecystectomy,with an acceptable negative rate of endoscopic retrograde cholangiopancreatography.METHODS:All patients with symptomatic gallstones were included in the study.Patients with abnormal liver functions and common bile duct abnormalities on ultrasound were referred for endoscopic retrograde cholangiopancreatography.Patients with normal ultrasoundwere referred to magnetic resonance cholangiopancreatography.All those who had a negative magnetic resonance or endoscopic retrograde cholangiopancreatography underwent laparoscopic cholecystectomy with intraoperative cholangiography.RESULTS:Seventy-eight point five percent of patients had laparoscopic cholecystectomy directly with no further investigations.Twenty-one point five percent had abnormal liver function tests,of which 52.8%had normal ultrasound results.This strategy avoided unnecessary magnetic resonance cholangiopancreatography in 47.2%of patients with abnormal liver function tests with a negative endoscopic retrograde cholangiopancreatography rate of 10%.It also avoided un-necessary endoscopic retrograde cholangiopancreatography in 35.2%of patients with abnormal liver function.CONCLUSION:This strategy reduces the cost of the routine use of magnetic resonance cholangiopancreatography,in the diagnosis and treatment of common bile duct stones before laparoscopic cholecystectomy. | Bilal O Al-Jiffry Abdeen Elfateh Tariq Chundrigar Bassem Othman Owaid AlMalki Fares Rayza Hashem Niyaz Hesham Elmakhzangy Mohammed Hatem | 2013 | World Journal of Gastroenterology2013，19，35： | 6 |
| 3 | Relationship between Crohn’s disease, infection with Mycobacterium avium subspecies paratuberculosis and SLC11A1 gene polymorphisms in Sardinian patients显示文摘AIM: To study the association between Crohn’s disease (CD), Mycobacterium avium subspecies paratubercu- losis (MAP), and genetic factors by examining the role of natural resistance-associated macrophage protein 1 (NRAMP1) gene polymorphisms (now SLC11A1) in Sar dinian patients with CD and controls. METHODS: Thirty-seven CD patients and 34 controls with no inflammatory bowel disease (IBD) were recruited at the University of Sassari after giving written con sent. Six SCL11A1 polymorphisms previously reported to be the most significantly associated with IBD were searched. M. paratuberculosis was identified by IS900 PCR and sequencing. Logistic regression was used to cal culate odds ratios (OR) for the associations among CD presence of MAP, and 6 loci described above. RESULTS: For the first time, a strong association was observed between polymorphisms at NRAMP1 locus 823C/T and CD. While CD was strongly associated withboth NRAMP1 and MAP, NRAMP1 polymorphisms and MAP themselves were not correlated. CONCLUSION: Combined with previous work on the NOD2/CARD15 gene, it is clear that the interplay of ge- netic, infectious, and immunologic factors in the etiology of CD is complex. | Leonardo A Sechi Maria Gazouli Lee E Sieswerda Paola Molicotti Niyaz Ahmed John Ikonomopoulos Antonio M Scanu Daniela Paccagnini Stefania Zanetti | 2006 | World Journal of Gastroenterology2006，12，44： | 3 |
| 4 | Study on ecological migration in Xinjiang, China显示文摘This paper expounds on the meaning of migration and the status quo of studies at home and abroad on migration and ecological migration. It focuses on the discussion of the necessity of ecological migration in Xinjiang, and the problems faced by the ecological emigrants, such as the lack of water, the serious land salination and basification, sand storms, and the adaptation to the environment. Besides, it probes into the problems existing in the ecological migration, including the unscientific design of the moving project, the defects of the reclamation work, and the irrational treatment of the relation between ecological migration and regional development. Based on this, we put forward some suggestions about and countermeasures against those problems. | Abliz Yusup Osman Niyaz | 2006 | Ecological Economy2006，2，3： | 1 |
| 5 | MCI 186 prevents brain tissue from neuronal damage in cerebral infarction through the aetivation of intracellular signaling显示文摘 | Niyaz M Numakawa T Matsuki Y | 2007 | J Neurosei Res2007，85，13： | 1 |
| 6 | A validated HPTLC method for determination of terbutaline sulfate in bio- logical samples: Application to pharmacokinetic study显示文摘 | Md Faiyazuddin Abdul Rauf Niyaz Ahmad | 2011 | Saudi Pharmaceutical Journal2011，3，18： | 1 |
| 7 | Reproducibility and Tolerability of the ICare Rebound Tonometer in School Children显示文摘 | Afsun Sahin Hikmet Basmak Leyla Niyaz Nilgun Yildirim | 2007 | Journal of Glaucoma2007，，2： | 1 |
| 8 | Removal of adhesive wound dressing and its effects on the stratum corneum of the skin: comparison of eight different adhesive wound dressings显示文摘 | Hajime Matsumura Ryutaro Imai Niyaz Ahmatjan Yukiko Ida Masahide Gondo Dai Shibata Katsueki Wanatabe | 2014 | International Wound Journal2014，，1： | 1 |
| 9 | MCI-186 prevents brain tissue from neuronal damage in cerebral infarction through the activation of intracellular signaling显示文摘 | Niyaz M Numakawa T Matsuki Y | 2007 | J Neruosci Res2007，85，13： | 1 |
| 10 | FLeproducibility and tolerability of the IOare rebound tonometer in school children显示文摘 | 8ahin A Basmak H Niyaz et a | 2007 | J Glaucoma2007，，18： | 1 |
| 11 | Rosiglitazone attenuates the severity of hyperlipidemic severe acute pancreatitis in rats显示文摘 | Niyaz B Zhao KL Liu LM | 2013 | Exp Ther Med2013，6，4： | 1 |
| 12 | Oxidation of dyes from colored wastewater using activated carbon/hydrogen peroxide显示文摘 | Shooka Khorramfar Niyaz Mohammad Mahmoodi Mokhtar Arami Hajir Bahrami | 2011 | Desalination2011，，1： | 1 |
| 13 | The hsp70-associating protein Hap46 binds to DNA and stimulates transcription显示文摘 | Zeiner M Niyaz Y Gehring U | 1999 | Proc Nail Acad Sci USA1999，96，10： | 1 |
| 14 | Quaternization of poly(4-viuyl pyridine) beads with 2-chloroacetamide for selective mercury extraction显示文摘 | Bulbul S H Niyaz B | 2002 | Reactive & Functional Polymers2002，51，： | 1 |
| 15 | Reproducibility and tolerabil-ity of the Icare rebound tonometer in school children显示文摘 | Sahin A Basmak H Niyaz L | 2007 | J Glauco- ma2007，16，2： | 1 |
| 16 | Binary system dye removal from colored textilewastewater using activated carbon:kinetic and isothermstudies显示文摘 | Niyaz Mohammad Mahmoodi Raziyeh Salehi MokhtarArami | 2011 | Desalination2011，272，13： | 1 |
| 17 | Transcriptional stimulation by the DNA binding protein Hap46/BAG-1M involves hsp70/hsc70 molecular chaperones显示文摘 | Niyaz Y Frenz I Petersen G | 2003 | Nucleic Acids Res2003，31，8： | 1 |
| 18 | Dye removal from colored textile wastewaterusing acrylic grafted nanomembrane显示文摘 | Masoud Amini Mokhtar Arami Niyaz Mohammad Mah-moodi | 2011 | Desalination2011，267，1： | 1 |
| 19 | Mycobacterium avium subspecies paratuberculosis infects and multiplies in enteric glial cells显示文摘AIM: To establish the role of enteric glial cells during infection with Mycobacterium avium subspecies paratuberculosis (MAP) in Crohn's disease. METHODS: In order to establish the role of enteric glial cells during infection with M. avium subspecies paratuberculosis (MAP) in Crohn's disease, Map adhesion experiments on enteric glial cells were performed as well as expression analysis of Map sigma factors during infection. RESULTS: In this study, for the first time, we found a high affinity of MAP to enteric glial cells and we analyzed the expression of MAP sigma factors under different conditions of growth. CONCLUSION: The fact that Map showed a high affinity to the glial cells raises concerns about the complicated etiology of the Crohn's disease. Elucidation of the mechanisms whereby inflammation alters enteric neural control of gut functions may lead to novel treatments for Crohn's disease. | Leonardo A Sechi Anne Ruehl Niyaz Ahmed Donatella Usai Daniela Paccagnini Giovanna E Felis Stefania Zanetti | 2007 | World Journal of Gastroenterology2007，13，43： | 1 |
| 20 | 2788 healthy young unmarried premarital HIV voluntary counseling and check AIDS显示文摘 | Coulee Rozi hot Niyaz Yan Li JY camps | 2006 | Chin J AIDS & STD2006，12，3： | 1 |
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