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| 1 | Studies on the overexpression of the soybean GmNHX1 in Lotus corniculatus: The reduced Na^+ level is the basis of the increased salt tolerance显示文摘The full length cDNA coding for a novel vacuolar Na+/H+ antiporter (GmNHX1) was cloned from soybean and determined to consist of 2591 bp with a 5′-untranslated region of 464 bp, an open reading frame (ORF) of 1641 bp, and a 3′-untrans- lated region of 486 bp. The deduced protein se- quence contains 546 aa with the typical characters of the vacuolar Na+/H+ antiporters, and shares high similarity with that of AtNHX1, OsNHX1 and AgNHX1. The soybean genome showed a single copy of the GmNHX1 gene. Northern blot analysis demonstrated that the expression of the GmNHX1 was tissue-spe- cific, increased by ABA treatment, NaCl, KCl, LiCl and dehydration stress, and lower in leaves but higher in roots and hypocotyls of salt-tolerant than salt-sensitive cultivars. The GmNHX1 was overex- pressed under the control of a tandem cauliflower mosaic virus (CaMV) 35S promoter in the model le- guminous plant Lotus corniculatus L. and conferred salt-tolerance of the transgenic plants. Measure- ments of Na+ and K+ contents in both roots and shoots demonstrated that the plantlets of GmNHX1- overexpressing lines had lower Na+ and K+ content, and higher K+/Na+ ratio than the controlled lines that were transformed with the empty vector, which indi- cates that the salt-tolerance conferred by GmNHX1 is closely related with decreased accumulation of Na+ in the transgenic plants. | SUN Yanxiang WANG Dan BAI Yanling WANG Ningning WANG Yong | 2006 | Chinese Science Bulletin2006，51，11： | 10 |
| 2 | Histone demethylase LSD1 regulates bone mass by controlling WNT7B and BMP2 signaling in osteoblasts显示文摘Multiple regulatory mechanisms control osteoblast differentiation and function to ensure unperturbed skeletal formation and remodeling. In this study we identify histone lysine-specific demethylase 1(LSD1/KDM1 A) as a key epigenetic regulator of osteoblast differentiation. Knockdown of LSD1 promoted osteoblast differentiation of human mesenchymal stem cells(hMSCs)in vitro and mice lacking LSD1 in mesenchymal cells displayed increased bone mass secondary to accelerated osteoblast differentiation. Mechanistic in vitro studies revealed that LSD1 epigenetically regulates the expression of WNT7 B and BMP2. LSD1 deficiency resulted in increased BMP2 and WNT7 B expression in osteoblasts and enhanced bone formation, while downregulation of WNT7 B-and BMP2-related signaling using genetic mouse model or small-molecule inhibitors attenuated bone phenotype in vivo. Furthermore, the LSD1 inhibitor tranylcypromine(TCP) could increase bone mass in mice. These data identify LSD1 as a novel regulator of osteoblast activity and suggest LSD1 inhibition as a potential therapeutic target for treatment of osteoporosis. | Jun Sun Joerg Ermann Ningning Niu Guang Yan Yang Yang Yujiang Shi Weiguo Zou | 2018 | Bone Research2018，6，3： | 5 |
| 3 | Large-area high quality PtSe2 thin film with versatile polarity显示文摘Two-dimensional(2D)materials have attracted increasing attention for their outstanding structural and electrical properties.However,for mass-production of field effect transistors(FETs)and potential applications in integrated circuits,large-area and uniform 2D thin films with high mobility,large on-off ratio,and desired polarity are needed to synthesize firstly.Here,a transfer-free growth method for platinum diselenide(PtSe2)films has been developed.The PtSe2 films have been synthesized with various thicknesses in centimeter-sized scale.Typical FET made from a few layer PtSe2 show p-type unipolar,with a high field-effect hole mobility of 6.2 cm^(2) V^(−1) s^(−1) and an on-off ratio of 5×10^(3).The versatile semimetal-unipolar-ambipolar transition in synthesized PtSe2 films is also firstly observed as the thickness thinning.This work realizes the large-scale preparation of PtSe2 with prominent electrical properties and provides a new strategy for polarity's modulation. | Wei Jiang Xudong Wang Yan Chen Guangjian Wu Kun Ba Ningning Xuan Yangye Sun Peng Gong Jingxian Bao Hong Shen Tie Lin Xiangjian Meng Jianlu Wang Zhengzong Sun | 2019 | InfoMat2019，1，2： | 5 |
| 4 | Mechanism of dust removal by a standing wave electric curtain显示文摘In this paper,the mechanisms of particle movement on an electric curtain are examined.Intermittent bursts in which particles leaping from a surface of an electric curtain are demonstrated both by numerical simulation and experimental observation.The hopping and surfing modes during particle removal are shown to depend on the particle electric charge and its initial position.The particles initially located on the top of electrode have a large electric charge tend to assume a hopping mode.Transverse movement of the particle initially located between the electrodes is analyzed,and the particle traps along the electric curtain surface are also observed. | SUN QiXia YANG NingNing CAI XiaoBing HU GengKai | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，6： | 4 |
| 5 | A Unified Approach to Construct Generalized B-Splines for Isogeometric Applications显示文摘Generalized B-splines have been employed as geometric modeling and numerical simulation tools for isogeometric analysis(IGA for short). However, the previous models used in IGA,such as trigonometric generalized B-splines or hyperbolic generalized B-splines, are not the unified mathematical representation of conics and polynomial parametric curves/surfaces. In this paper,a unified approach to construct the generalized non-uniform B-splines over the space spanned by{α(t), β(t), ξ(t), η(t), 1, t, ···, t^(n-4)} is proposed, and the corresponding isogeometric analysis framework for PDE solving is also studied. Compared with the NURBS-IGA method, the proposed frameworks have several advantages such as high accuracy, easy-to-compute derivatives and integrals due to the non-rational form. Furthermore, with the proposed spline models, isogeometric analysis can be performed on the computational domain bounded by transcendental curves/surfaces, such as the involute of circle, the helix/helicoid, the catenary/catenoid and the cycloid. Several numerical examples for isogeometric heat conduction problems are presented to show the effectiveness of the proposed methods. | XU Gang SUN Ningning XU Jinlan HUI Kin-Chuen WANG Guozhao | 2017 | Journal of Systems Science & Complexity2017，30，4： | 3 |
| 6 | A High-Accuracy Single Patch Representation of Multi-Patch Geometries with Applications to Isogeometric Analysis显示文摘This paper presents a novel approximating method to construct highprecision single-patch representation of B-spline surface from a multi-patch representation for isogeometric applications.In isogeometric analysis,multi-patch structure is not easy to achieve high continuity between neighboring patches which will reduce the advantage of isogeometric analysis in a sense.The proposed method can achieve high continuity at surface stitching region with low geometric error,and this technique exploits constructing the approximate surface with several control points are from original surfaces,which guarantees the local feature of the surface can be well-preserved with high precision.With the proposed approximating method,isogeometric analysis results using the new single-patch can be obtained efficiently compared with the original multi-patch structure.Several examples are presented to illustrate the effectiveness,accuracy and efficiency of the proposed method. | Jinlan Xu Ningning Sun Gang Xu | 2020 | Computer Modeling in Engineering & Sciences2020，，8： | 2 |
| 7 | Morphological Development of Fuel Droplets after Impacting Biomimetic Structured Surfaces with Different Temperatures显示文摘To improve the controllability for the evaporation process of fuel spray impinging on the cylinder wall,an experimental study on the development of morphological process of different fuel droplets on aluminium alloy surfaces is carried out.The metal surfaces with different wettability are prepared by laser etching and chemical etching for the experiments.In total,three different fuels are tested and compared under different surface temperatures,including diesel,n-butanol and dimethyl carbonate(DMC).The results show that under a lower wall temperature,the surface wettability,viscosity and surface tension of the fuels have significant effects on spreading and rebounding behaviour of the droplets.As the wall temperature rises over the boiling points of the fuel but below its Leidenfrost temperature,the contact angles between the fuels and surfaces are varying according to the surface wettability,boiling point and Leidenfrost temperature of the fuels.When the temperature of the surface exceeds the Leidenfrost temperature of all the fuels,after impacting the surfaces,different fuel droplets tend to have the same development pattern,regardless of the surface wettability.The rebound level is mainly affected by the amount of fuel vapour generated during the wall-hitting process.Viscosity,surface tension and other properties of the fuel have little effect on post-impacting behaviour of the droplet when the wall temperature is higher than the Leidenfrost temperature of the fuel. | Liang Guo Yuheng Gao Ningning Cai Degang Li Yuying Yan Wanchen Sun | 2020 | Journal of Bionic Engineering2020，17，4： | 2 |
| 8 | Recent progress on chikungunya virus research显示文摘Chikungunya virus(CHIKV) is an arbovirus transmitted by Aedes mosquitos in tropical and subtropical regions across the world. After decades of sporadic outbreaks, it re-emerged in Africa,Asia, India Ocean and America suddenly, causing major regional epidemics recently and becoming a notable global health problem. Infection by CHIKV results in a spectrum of clinical diseases including an acute self-limiting febrile illness in most individuals, a chronic phase of recurrent join pain in a proportion of patients, and long-term arthralgia for months to years for the unfortunate few. No specific anti-viral drugs or licensed vaccines for CHIKV are available so far. A better understanding of virus-host interactions is essential for the development of therapeutics and vaccines. To this end, we reviewed the existing knowledge on CHIKV's epidemiology, clinical presentation, molecular virology, diagnostic approaches, host immune response, vaccine development, and available animal models. Such a comprehensive overview, we believe, will shed lights on the promises and challenges in CHIKV vaccine development. | Wenxi An Ningning Ge Yilin Cao Jin Sun Xia Jin | 2017 | Virologica Sinica2017，32，6： | 2 |
| 9 | Sandwiched N-carbon@Co_(9)S_(8)@Graphene nanosheets as high capacity anode for both half and full lithium-ion batteries显示文摘Transition metal sulfides(TMSs) are promising candidates for replacing graphite anode in LIBs. However,the low conductivity and structural collapse caused by the large volume change during lithium insertion and extraction greatly limit its application. Herein, we report a unique design of a two-dimensional(2 D) sandwich structure of N-doped carbon@Co9 S8@graphene(N–C@Co9 S8@G) with multilayer structure. Electrochemical tests reveal that the N–C@Co9 S8@G nanosheets possess a high reversible capacity(1009 mAhg^(-1) at 0.1 Ag^(-1)), and excellent rate capability(422mAhg^(-1) at 10 Ag^(-1)) and long cycle life(853 m Ahg^(-1) at 1Ag^(-1) for 500 cycles). Experimental studies reveal that capacitive storage contributes to the high reversible capacity. The lithium storage kinetics are studied by Galvanostatic intermittent titration technique(GITT) and electrochemical impedance spectroscopy(EIS). Meanwhile, the potential of N–C@Co9 S8@G anode in a full cell using Li Co O2 as the cathode is also demonstrated, exhibiting a high reversible capacity of 300mAhg^(-1) cycles at 0.1Ag^(-1). The strategy proposed in this work paves the way to engineering high performance anodes in LIBs. | Ningning Li Li Sun Kai Wana Sheng Xu Jun Zhang Xiangxin Guo Xianghong Liu | 2020 | Journal of Energy Chemistry2020，29，12： | 2 |
| 10 | Multilayered structure of N-carbonenvelopediron oxide/graphene nanocomposites as an improved anode for Li-ion battery显示文摘Transition metal oxides with high capacity are considered a promising electrode material for lithium-ion batteries(LIBs).Nevertheless,the huge volume expansion and poor conductivity severely hamper their practical application.In this work,a carbon riveting method is reported to address the above issues by designing multilayered N-doped carbon(N-carbon) enveloped Fe3O4/graphene nanosheets.When evaluated as a negative electrode,the N-carbon/Fe3O4/graphene nanocomposites demonstrate greatly enhanced electrochemical properties compared with Fe3O4/graphene.The N-carbon/Fe3O4/graphene presents a superior reversible capacity(807 mAh/g) over Fe3O4/graphene(540 mAh/g).Furthermore,it affords a considerable capacity of 550 mAh/g at 1 A/g over 700 cycles,indicating supe rb cycling stability.The structure-property correlation studies reveal that the carbon riveting layer is essential for enhancing the lithium diffusion kinetics.The good electrochemical properties and effective structure design make the carbon riveting strategy quite general and reliable to manipulate high performance electrodes for future LIBs. | Li Sun Kai Wang Ningning Li Jun Zhang Xiangxin Guo Xianghong Liu | 2020 | Chinese Chemical Letters2020，31，9： | 2 |
| 11 | The sensitivity of the array resistivity log to mud filtrate invasion and its primary five-parameter inversion for improved oil water recognition显示文摘In order to improve reservoir fluid recognition, the sensitivity of array resistivity response to the difference of the invasion properties in both oil-bearing layers and water layers is analyzed. Then the primary inversion is carried out based on the array resistivity log. The mud invasion process is numerically simulated based on the oil-water flow equation and water convection diffusion equation. The results show that the radial resistivity of a fresh mud-invaded oil-bearing layer presents complex distribution characteristics, such as nonlinear increase, increasing to decreasing and low resistivity annulus, and the resistive invasion profile of a water layer is monotonic. Under specific conditions, array resistivity log can reflect these changes and the array induction log is more sensitive. Nevertheless, due to the effect of factors like large invasion depth, reservoir physical and oil-bearing properties, the measured apparent resistivity may differ greatly from the actual mud filtrate invasion profile in an oil-bearing layer. We proposed a five-parameter formation model to simulate the complex resistivity distribution of fresh mud-invaded formation. Then, based on the principle of non-linear least squares, the measured array resistivity log is used for inversion with the Marquardt method. It is demonstrated that the inverted resistivity is typically non-monotonic in oil-bearing layers and is monotonic in water layers. Processing of some field data shows that this is helpful in achieving efficient reservoir fluid recognition. | Deng Shaogui Sun Qingtao Li Hu Huo Ningning He Xuquan | 2012 | Petroleum Science2012，9，3： | 2 |
| 12 | Recent progress of efficient utilization of titanium-bearing blast furnace slag显示文摘Titanium-bearing blast furnace slag(BFS)has valuable compositions and potential environmental hazardousness.Thus,developing efficient and green approaches to utilize BFS is highly desired for resource economization and environmental protection.In the past decades,many attempts have been adopted to reuse BFS efficiently,and significant advances in understanding the fundamental features and the development of efficient approaches have been achieved.This review provides a comprehensive overview of the latest progress on the efficient utilization of BFS and discusses the mechanism and characteristics of various approaches,along with their application prospects.In particular,the extraction and enrichment of titanium-bearing phases from BFS are highlighted because of the high availability of titanium resources.This systemic and comprehensive review may benefit the design of new and green utilization routes with high efficiency and low cost. | Yongfeng Cai Ningning Song Yunfei Yang Lingmin Sun Peng Hu Jinshu Wang | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，1： | 2 |
| 13 | Synthesis of La_(0.9)Sr_(0.1)Ga_(0.8)Mg_(0.2)O_(3-δ) Powder for Solid Oxide Fuel Cell by a Nitrate-Citrate Combustion Route显示文摘A nitrate-citrate combustion route to synthesize La0.9Sr0.1 Ga0.8 Mg0.2O3-δ powder for solid oxide fuel cell application was presented. This route is based on the gelling of nitrate solutions by the addition of citric acid and ammonium hydroxide, followed by an intense combustion process due to an exothermic redox reaction between nitrate and citrate ions. The optimum technical parameters are that the pH value is 5, and the molar ratio of citric acid to the total metallic ion is 1.5:1. X-ray diffraction characterization of calcined gel shows that pure phase was synthesized after calcination at 1400℃ for 10 h, and the TEM result shows the calcined powder with average particle size is about 150 nm. The grain resistance contributes to the total resistance of sintered pellet below 500℃. The conductivity of the sintered pellent at 800℃ was 0.07 S-1.cm-1 higher than the conductivity of YSZ(0.05S-1.cm-1 at 800℃) | Naiqing ZHANG, Kening SUN, Derui ZHOU and Ningning WUHarbin Institute of Technology, Harbin 150001, China | 2004 | Journal of Materials Science & Technology2004，20，6： | 2 |
| 14 | The Cloud Storage Ciphertext Retrieval Scheme Based on ORAM显示文摘 | SONG Ningning SUN Yan | 2014 | China Communications2014，11，A02： | 1 |
| 15 | A facile method to synthesize carboxyl-functionalized magnetic polystyrene nanospheres 显示文摘 | Ningning Guan Chao Liu Dejun Sun | 2009 | Colloids and Surfaces A: Physicochemical and Engineering Aspects2009，335，： | 1 |
| 16 | Hybrid Triboelectric Nanogenerators:From Energy Complementation to Integration显示文摘Energy collection ways using solar energy,wave,wind,or mechanical energy have attracted widespread attention for small selfpowered electronic devices with low power consumption,such as sensors,wearable devices,electronic skin,and implantable devices.Among them,triboelectric nanogenerator(TENG)operated by coupling effect of triboelectrification and electrostatic induction has gradually gained prominence due to its advantages such as low cost,lightweight,high degree of freedom in material selection,large power,and high applicability.The device with a single energy exchange mechanism is limited by its conversion efficiency and work environment and cannot achieve the maximum conversion of energy.Thus,this article reviews the research status of different types of hybrid generators based on TENG in recent years.Hybrid energy generators will improve the output performance though the integration of different energy exchange methods,which have an excellent application prospect.From the perspective of energy complementation,it can be divided into harvesting mechanical energy by various principles,combining with harvesters of other clean energy,and converting mechanical energy or various energy sources into hydrogen energy.For integrating multitype energy harvesters,mechanism of single device and structural design of integrated units for different application scenarios are summarized.The expanding energy harvesting efficiency of the hybrid TENG makes the scheme of self-charging unit to power intelligent mobile electronic feasible and has practical significance for the development of self-powered sensor network. | Lingjie Xie Ningning Zhai Yina Liu Zhen Wen Xuhui Sun | 2021 | Research2021，，1： | 1 |
| 17 | An mRNA vaccine encoding Chikungunya virus E2-E1 protein elicits robust neutralizing antibody responses and CTL immune responses显示文摘Arthropod-borne chikungunya virus(CHIKV)infection can cause a debilitating arthritic disease in human.However,there are no specific antiviral drugs and effective licensed vaccines against CHIKV available for clinical use.Here,we developed an m RNA-lipid nanoparticle(m RNA-LNP)vaccine expressing CHIKV E2-E1 antigen,and compared its immunogenicity with soluble recombinant protein s E2-E1 antigen expressed in S2 cells.For comparison,we first showed that recombinant protein antigens mixed with aluminum adjuvant elicit strong antigenspecific humoral immune response and a moderate cellular immune response in C57BL/6 mice.Moreover,s E2-E1vaccine stimulated 12-23 folds more neutralizing antibodies than s E1 vaccine and s E2 vaccine.Significantly,when E2-E1 gene was delivered by an m RNA-LNP vaccine,not only the better magnitude of neutralizing antibody responses was induced,but also greater cellular immune responses were generated,especially for CD8+T cell responses.Moreover,E2-E1-LNP induced CD8~+T cells can perform cytotoxic effect in vivo.Considering its better immunogenicity and convenience of preparation,we suggest that more attention should be placed to develop CHIKV E2-E1-LNP m RNA vaccine. | Ningning Ge Jin Sun Zhihua Liu Jiayi Shu Huimin Yan Zhihua Kou Yu Wei Xia Jin | 2022 | Virologica Sinica2022，37，2： | 1 |
| 18 | Mass transfer techniques for large-scaleand high-density microLED arrays显示文摘Inorganic-based micro light-emitting diodes (microLEDs) offer more fascinating properties and unique demands in next-generation displays. However, the small size of the microLED chip (1–100 µm) makes it extremely challenging for high efficiency and low cost to accurately, selectively, integrate millions of microLED chips. Recent impressive technological advances have overcome the drawbacks of traditional pick-and-place techniques when they were utilized in the assembly of microLED display, including the most broadly recognized laser lift-off technique, contact micro-transfer printing (µTP) technique, laser non-contact µTP technique, and self-assembly technique. Herein, we firstly review the key developments in mass transfer technique and highlight their potential value, covering both the state-of-the-art devices and requirements for mass transfer in the assembly of the ultra-large-area display and virtual reality glasses. We begin with the significant challenges and the brief history of mass transfer technique, and expand that mass transfer technique is composed of two major techniques, namely, the epitaxial Lift-off technique and the pick-and-place technique. The basic concept and transfer effects for each representative epitaxial Lift-off and pick-and-place technique in mass transfer are then overviewed separately. Finally, the potential challenges and future research directions of mass transfer are discussed. | Furong Chen Jing Bian Jinlong Hu Ningning Sun Biao Yang Hong Ling Haiyang Yu Kaixin Wang Mengxin Gai Yuhang Ma YongAn Huang | 2022 | International Journal of Extreme Manufacturing2022，4，4： | 1 |
| 19 | Flexible multilayer lead-free film capacitor with high energy storage performances via heterostructure engineering显示文摘The immense potential of flexible energy storage materials applied in wearable electronic devices hasstimulated a lot of science researches on manufacturing technology and performance optimization.Herein, an all-inorganic flexible ferroelectric film with multilayer heterostructure is prepared based onMn doped Bi0.5Na0.5TiO_(3)eBiNi0.5Zr0.5O_(3) (Mn:BNT-BNZ) and Bi0.5Na0.5TiO_(3)eBiZn0.5Zr0.5O_(3) (BNT-BZZ)relaxor ferroelectrics. A win-win situation of breakdown strength and polarization is achieved in theMn:BNT-BNZ/BNT-BZZ multilayer film with the stacking period N - 3, of which energy density and ef-ficiency reach 80.4 J/cm3 and 62.0% respectively. It is proposed that the excellent energy storage per-formances are attributed to the synergistic effect of the electric field amplification effect, interfaceblocking effect and the polarization coupling effect based on the multilayer heterostructure. Moreover,the flexible ferroelectric film exhibits outstanding temperature (25e205 - C), frequency (0.5e5 kHz)stability and antifatigue property (1 108 cycles), and can well maintain stable performance at differenttensile/compressive bending radii (10e5 mm) and even after 104 bending cycles with a fixed bendingradius of 3 mm. This work opens up a promising route to the development of flexible energy storagematerials. | Ningning Sun Jinhua Du Ye Zhao Chunxiao Lu Pei Han Yong Li Qiwei Zhang Xihong Hao | 2022 | Journal of Materiomics2022，8，4： | 1 |
| 20 | Helicobacter pylori enhances cyclooxygenase 2 expression via p38MAPK/ATF-2 signaling pathway in MKN45 cells显示文摘 | Qi Li Ningning Liu Bo Shen Lihong Zhou Yan Wang Yiqin Wang Jue Sun Zhongze Fan Rui Hai Liu | 2009 | Cancer Letters2009，，1： | 1 |
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