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| 1 | Immunological synergistic mechanisms of trans-/cis-stilbene glycosides in Heshouwu-related idiosyncratic liver injury显示文摘Heshouwu is a traditional non-toxic Chinese medicine commonly used in the clinical setting;however,clinical cases of Heshouwu-induced hepatotoxicity have been frequently reported^([1]).Pharmacoepidemiological studies have found that Heshouwu-induced liver injury occurs only in a small fraction of individuals taking the drug;these patients presented with the typ- | Lanzhi He Ping Yin Yakun Meng Jinfa Tang Tingting He Ming Niu Yuming Guo Yun Zhu Jing Jing Chunyu Li Zhijie Ma Jiabo Wang Zhaofang Bai Xiaohe Xiao | 2017 | Science Bulletin2017，62，11： | 29 |
| 2 | Landscape of DILI-related adverse drug reaction in China Mainland显示文摘Drug-induced liver injury(DILI)is a type of bizarre adverse drug reaction(ADR)damaging liver(L-ADR)which may lead to substantial hospitalizations and mortality.Due to the general low incidence,detection of L-ADR remains an unsolved public health challenge.Therefore,we used the data of 6.673 million of ADR reports from January 1st,2012 to December 31st,2016 in China National ADR Monitoring System to establish a new database of L-ADR reports for future investigation.Results showed that totally 114,357 ADR reports were retrieved by keywords searching of liver-related injuries from the original heterogeneous system.By cleaning and standardizing the data fields by the dictionary of synonyms and English translation,we resulted 94,593 ADR records reported to liver injury and then created a new database ready for computer mining.The reporting status of L-ADR showed a persistent 1.62-fold change over the past five years.The national population-adjusted reporting numbers of L-ADR manifested an upward trend with age increasing and more evident in men.The annual reporting rate of L-ADR in age group over 80 years old strikingly exceeded the annual DILI incidence rate in general population,despite known underreporting situation in spontaneous ADR reporting system.The percentage of herbal and traditional medicines(H/TM)L-ADR reports in the whole number was 4.5%,while 80.60%of the H/TM reports were new findings.There was great geographical disparity of reported agents,i.e.more cardiovascular and antineoplastic agents were reported in higher socio-demographic index(SDI)regions and more antimicrobials,especially antitubercular agents,were reported in lower SDI regions.In conclusion,this study presented a large-scale,unbiased,unified,and computer-minable L-ADR database for further investigation.Age-,sex-and SDI-related risks of L-ADR incidence warrant to emphasize the precise pharmacovigilance policies within China or other regions in the world. | Jiabo Wang Haibo Song Feilin Ge Peng Xiong Jing Jing Tingting He Yuming Guo Zhuo Shi Chao Zhou Zixin Han Yanzhong Han Ming Niu Zhaofang Bai Guangbin Luo Chuanyong Shen Xiaohe Xiao | 2022 | Acta Pharmaceutica Sinica B2022，12，12： | 12 |
| 3 | Influence of physical properties of carrier on the performance of dry powder inhalers显示文摘Dry powder inhalers(DPIs) offer distinct advantages as a means of pulmonary drug delivery and have attracted much attention in the field of pharmaceutical science. DPIs commonly contain micronized drug particles which, because of their cohesiveness and strong propensity to aggregate, have poor aerosolization performance. Thus carriers with a larger particle size are added to address this problem. However, the performance of DPIs is profoundly influenced by the physical properties of the carrier, particularly their particle size, morphology/shape and surface roughness. Because these factors are interdependent, it is difficult to completely understand how they individually influence DPI performance.The purpose of this review is to summarize and illuminate how these factors affect drug–carrier interaction and influence the performance of DPIs. | Tingting Peng Shiqi Lin Boyi Niu Xinyi Wang Ying Huang Xuejuan Zhang Ge Li Xin Pan Chuanbin Wu | 2016 | Acta Pharmaceutica Sinica B2016，6，4： | 8 |
| 4 | A pair of light signaling factors FHY3 and FAR1 regulates plant immunity by modulating chlorophyll biosynthesis显示文摘Light and chloroplast function is known to affect the plant immune response; however, the underlying mechanism remains elusive. We previously demonstrated that two light signaling factors, FAR-RED ELONGATED HYPOCOTYL 3(FHY3)and FAR-RED IMPAIRED RESPONSE 1(FAR1), regulate chlorophyll biosynthesis and seedling growth via controlling HEMB1 expression in Arabidopsis thaliana. In this study, we reveal that FHY3 and FAR1 are involved in modulating plant immunity. We showed that the fhy3 far1 double null mutant displayed high levels of reactive oxygen species and salicylic acid(SA) and increased resistance to Pseudomonas syringae pathogen infection. Microarray analysis revealed that a large proportion of pathogen-related genes, particularly genes encoding nucleotide-binding and leucine-rich repeat domain resistant proteins, are highly induced in fhy3 far1. Genetic studies indicated that the defects of fhy3 far1 can be largely rescued by reducing SA signaling or blocking SA accumulation, and by overexpression of HEMB1, which encodes a 5-aminolevulinic acid dehydratase in the chlorophyll biosynthetic pathway.Furthermore, we found that transgenic plants with reduced expression of HEMB1 exhibit a phenotype similar to fhy3 far1.Taken together, this study demonstrates an important role of FHY3 and FAR1 in regulating plant immunity, through integrating chlorophyll biosynthesis and the SA signaling pathway. | Wanqing Wang Weijiang Tang Tingting Ma De Niu Jing Bo Jin Haiyang Wang Rongcheng Lin | 2016 | Journal of Integrative Plant Biology2016，58，1： | 8 |
| 5 | Model tests on XCC-piled embankment under dynamic train load of high-speed railways显示文摘Piled embankments,which offer many advantages,are increasingly popular in construction of high-speed railways in China.Although the performance of piled embankment under static loading is well-known,the behavior under the dynamic train load of a high-speed railway is not yet understood.In light of this,a heavily instrumented piled embankment model was set up,and a model test was carried out,in which a servo-hydraulic actuator outputting M-shaped waves was adopted to simulate the process of a running train.Earth pressure,settlement,strain in the geogrid and pile and excess pore water pressure were measured.The results show that the soil arching height under the dynamic train load of a high-speed railway is shorter than under static loading.The growth trend for accumulated settlement slowed down after long-term vibration although there was still a tendency for it to increase.Accumulated geogrid strain has an increasing tendency after long-term vibration.The closer the embankment edge,the greater the geogrid strain over the subsoil.Strains in the pile were smaller under dynamic train loads,and their distribution was different from that under static loading.At the same elevation,excess pore water pressure under the track slab was greater than that under the embankment shoulder. | Niu Tingting Liu Hanlong Ding Xuanming Zheng Changjie | 2018 | Earthquake Engineering and Engineering Vibration2018，17，3： | 6 |
| 6 | Effect of electric intensity on the microbial degradation of petroleum pollutants in soil显示文摘Electro-bioremediation is an innovative method to remedy organic-polluted soil. However, the principle of electrokinetic technology enhancing the function of microbes, especially the relationship of electric intensity and biodegradation efficiency, is poorly investigated. Petroleum was employed as a target organic pollutant at a level of 50 g/kg (mass of petroleum/mass of dry soil). A direct current power supply was used for tests with a constant direct current electric voltage (1.0 V/cm). The petroleum concentrations were measured at 3275–3285 nm after extraction using hexane, the group composition of crude oil was analyzed by column chromatography. The water content of soil was kept 25% (m/m). The results indicated the degradation process was divided into two periods: from day 1 to day 40, from day 41 to day 100. The treatment of soil with an appropriate electric field led the bacteria to have a persistent effect in the whole period of 100 days. The highest biodegradation efficiency of 45.5% was obtained after treatment with electric current and bacteria. The electric-bioremediation had a positive effect on alkane degradation. The degradation rate of alkane was 1.6 times higher in the soil exposed to electric current than that treated with bacteria for 100 days. A proper direct current could stimulate the microbial activities and accelerate the biodegradation of petroleum. There was a positive correlation between the electric intensities and the petroleum bioremediation efficiencies with a coefficient of 0.9599. | Tingting Li Shuhai Guo Bo Wu Fengmei Li Zhixin Niu | 2010 | Journal of Environmental Sciences2010，22，9： | 6 |
| 7 | OsbZIP76 interacts with OsNF-YBs and regulates endosperm cellularization in rice (Oryza sativa)显示文摘Following double fertilization,plant endosperm nuclei undergo syncytial divisions,followed by synchro-nous cellularization.Cellularization is a key event during endosperm development,but our understanding of its regulation is limited to Arabidopsis.In this study we show that OsbZIP76 regulates cellularization in rice(Oryza sativa).Activation of OsbZIP76 coincided with the initiation of cellularization,and its knockdown or knockout mutants exhibited precocious cellularization.Genes involved in en-dosperm development or starch biosynthesis were pre-maturely activated in the osbzip76 caryopsis.As a putative transcription factor,OsbZIP76 alone lacked transcriptional activation activity;however,it interacted with the nuclear factor Y(NF-Y)family transcription factors OsNF-YB9 and OsNF-YB1 in yeast and in planta.OsbZIP76 and OsNF-YB9 were predominantly expressed in the endosperm and the proteins colocalized.Seeds of osnf-yb1 and osbzip76 mu-tants showed reduced size and reduced apparent amylose content.The parent-of-origin-dependent expression of OsbZIP76 is variable in different rice accessions.In sum-mary,OsbZIP76 is an endosperm-expressed imprinted gene that regulates endosperm development in rice. | Baixiao Niu Hui Deng Tingting Li Sandeep Sharma Qianbin Yun Qianru Li Zhiguo E Chen Chen | 2020 | Journal of Integrative Plant Biology2020，62，12： | 4 |
| 8 | Effect of fructooligosaccharides on the colonization of Lactobacillus rhamnosus AS 1.2466^(T) in the gut of mice显示文摘Lactobacillus rhamnosus and fructooligosaccharides(FOS)have been widely studied so far.However,the effects of L.rhamnosus on the intestinal microecological environment at the species level and the effect of different proportions of FOS on L.rhamnosus colonization in different parts of mice intestine are still unclear.The study results indicated that the specific bands of enterobacterial repetitive intergenic consensus polymerase chain reaction(ERIC-PCR)in the L.rhamnosus(LR)group significantly increased at 7 days.Although the number of bands was similar to the natural recovery(NR)group,the brightness of few bands significantly enhanced in the later stage of recovery.Besides,Southern-blot maps showed strong signals,indicating that the ERIC-PCR fingerprint could accurately reflect the changes in the mouse gut microbiota diversity.Further,the high-throughput results confirmed that the Lactobacillus and Akkermansia had different changes at different periods,but all of them showed an upward trend,while the Klebsiella were inhibited,thereby maintaining the intestinal microecology balance.Moreover,FOS exerted a positive effect on L.rhamnosus colonization in the gut. | Zhihua Niu Meijuan Zou Tingting Bei Na Zhang Dongyao Li Miaoshu Wang Chen Li Hongtao Tian | 2023 | Food Science and Human Wellness2023，12，2： | 3 |
| 9 | High visible light photocatalytic activities obtained by integrating g-C_(3)N_(4) with ferroelectric PbTiO_(3)显示文摘Graphitic carbon nitride(g-C_(3)N_(4))with the merits of high visible light absorption,proper electronic band structure with high conduction band edge and variable modulation,is viewed as a promising photocatalyst for practical use.To alleviate its high recombination rate of photo-excited charge carriers and maximize the photocatalytic performances,it is paramount to design highly effective transfer channels for photo-excited charge carriers.Ferroelectric materials can have the charge carriers transport in opposite directions owing to the internal spontaneous polarization,which may be suitable for constructing the heterostructure with g-C_(3)N_(4)for efficient charge separation.Inspired by this concept,herein ferroelectric PbTiO_(3),which can be the visible-light absorber,is coupled with g-C_(3)N_(4)to construct PbTiO_(3)/g-C_(3)N_(4)heterostructure with close contact via Pb–N bond by the facile post thermal treatment.The optimized Pb TiO_(3)/g-C_(3)N_(4)heterostructure exhibited excellent photocatalytic and photoelectrochemical activities under visible light irradiation.Moreover,the simultaneous application of ultrasound-induced mechanical waves can further improve its photocatalytic activities through reinforcing the built-in piezoelectric field.This work proposes a widely applicable strategy for the fabrication of high-performance ferroelectric based photocatalysts and also provides some new ideas for developing the understanding of ferroelectric photocatalysis. | Tingting Xu Ping Niu Shulan Wang Li Li | 2021 | Journal of Materials Science & Technology2021，，15： | 3 |
| 10 | Clinical characteristics of 96 patients with drug-induced acute liver failure:a comparison between Traditional Chinese and Western Medicine显示文摘OBJECTIVE: To compare the causes, clinical symptoms, laboratory test results, and prognosis in patients with acute liver failure(ALF) induced by traditional Chinese medicines(TCM) and by Western Medicines(WM).METHODS: The medical histories of patients who were diagnosed with drug-induced ALF(DALF)(n =96) after hospitalization in the 302 Military Hospital between January 2010 and December 2015 were retrospectively examined.RESULTS: Fifty-eight of the 96 DALF patients(60.4%) had a hepatocellular pattern of DALF, 16 patients(16.7%) had a cholestatic pattern, and 22 patients(22.9%) had a mixed pattern. DALF resolved in 24 patients(25.0%). Twenty-five patients(26.0%)developed chronic liver injury, 43 patients(44.8%)died, and 4 patients(4.2%) underwent liver transplantation. There were 42 ALF patients(43.8%) who received WM, and 32 ALF patients(33.3%) who received TCM. TCM-induced ALF patients had a higher average age [42.4 ± 18.4) vs(33.5 ± 17.9) years,P = 0.04] and higher creatinine and urine nitrogen levels [(155.2 ± 108.8) vs(97.5 ± 130.4) mmol/L, P =0.047;(9.1 ± 7.7) vs(4.3 ± 5.0) mmol/L, P = 0.002, respectively]. Patients with TCM-induced ALF exhibited an increased risk of renal injury [odds ratio(OR),3.75; 95% confidence interval(CI), 1.330-10.577].The 14 patients with TCM-induced ALF who died exhibited higher creatinine levels than the 18 patients with TCM-induced ALF patients who survived[(218.7 ± 111.6) vs(105.8 ± 78.4) mmol/L, P =0.002]. They were also more likely to exhibit ascites(85.7% vs 44.4%, P = 0.017) and hepatorenal syndrome(78.6% vs 22.2%, P = 0.002).CONCLUSION: TCM-induced ALF was more likely to be accompanied by renal injury than was WM-induced ALF, especially in TCM-induced ALF patients who died. | He Tingting Zhu Yun Wang Jiabo Gong Man Wang Ruilin Niu Ming Jing Jing Wang Lifu Wang Zhongxia Zhang Ning Bai Zhaofang Bai Yunfeng Li Yonggang Xiao Xiaohe | 2017 | Journal of Traditional Chinese Medicine2017，37，3： | 3 |
| 11 | Robust dynamic output feedback control for switched polytopic systems under asynchronous switching显示文摘The robust controller design problem for switched polytopic systems under asynchronous switching is addressed.These systems exist in many aviation applications, such as dynamical systems involving rapid variations.A switched polytopic system is established to describe the highly maneuverable technology vehicle within the full flight envelope and a robust dynamic output feedback control method is designed for the switched polytopic system.Combining the Lyapunov-like function method and the average dwell time method, a sufficient condition is derived for the switched polytopic system with asynchronous switching and data dropout to be globally,uniformly and asymptotically stable in terms of linear matrix inequality.The robust dynamic output feedback controller is then applied to the highly maneuverable technology vehicle to illustrate the effectiveness of the proposed approach.The simulation results show that the angle of attack tracking performance is acceptable over the time history and the control surface responses are all satisfying along the full flight trajectory. | Yang Tingting Li Aijun Niu Erzhuo | 2015 | Chinese Journal of Aeronautics2015，28，4： | 2 |
| 12 | Origin of High Efficiency and Long-Term Stability in Ionic Liquid Perovskite Photovoltaic显示文摘Environment-friendly protic amine carboxylic acid ionic liquids(ILs)as solvents is a significant breakthrough with respect to traditional highly coordinating and toxic solvents in achieving efficient and stable perovskite solar cells(PSCs)with a simple one-step air processing and without an antisolvent treatment approach.However,it remains mysterious for the improved efficiency and stability of PSCs without any passivation strategy.Here,we unambiguously demonstrate that the three functions of solvents,additive,and passivation are present for protic amine carboxylic acid ILs.We found that the ILs have the capability to dissolve a series of perovskite precursors,induce oriented crystallization,and chemically passivate the grain boundaries.This is attributed to the unique molecular structure of ILs with carbonyl and amine groups,allowing for strong interaction with perovskite precursors by forming C=O…Pb chelate bonds and N-H…I hydrogen bonds in both solution and film.This finding is generic in nature with extension to a wide range of IL-based perovskite optoelectronics. | Lingfeng Chao Tingting Niu Hao Gu Yingguo Yang Qi Wei Yingdong Xia Wei Hui Shouwei Zuo Zhaohua Zhu Chengjie Pei Xiaodong Li Jing Zhang Junfeng Fang Guichuan Xing Hai Li Xiao Huang Xingyu Gao Chenxin Ran Lin Song Li Fu Yonghua Chen Wei Huang | 2020 | Research2020，，1： | 2 |
| 13 | SEC1A and SEC6 synergistically regulate pollen tube polar growth显示文摘Pollen tube polar growth is a key physiological activity for angiosperms to complete double fertilization, which is highly dependent on the transport of polar substances mediated by secretory vesicles.The exocyst and Sec1/Munc18(SM) proteins are involved in the regulation of the tethering and fusion of vesicles and plasma membranes, but the molecular mechanism by which they regulate pollen tube polar growth is still unclear. In this study, we found that loss of function of SEC1A, a member of the SM protein family in Arabidopsis thaliana, resulted in reducing pollen tube growth and a significant increase in pollen tube width. SEC1A was diffusely distributed in the pollen tube cytoplasm, and was more concentrated at the tip of the pollen tube. Through coimmunoprecipitation-mass spectrometry screening,protein interaction analysis and in vivo microscopy,we found that SEC1A interacted with the exocyst subunit SEC6, and they mutually affected the distribution and secretion rate at the tip of the pollen tube. Meanwhile, the functional loss of SEC1A and SEC6 significantly affected the distribution of the SNARE(soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex member SYP125 at the tip of the pollen tube, and led to the disorder of pollen tube cell wall components. Genetic analysis revealed that the pollen tube-related phenotype of the sec1a sec6 double mutant was significantly enhanced compared with their respective single mutants. Therefore, we speculated that SEC1A and SEC6 cooperatively regulate the fusion of secretory vesicles and plasma membranes in pollen tubes, thereby affecting the length and the width of pollen tubes. | Tingting Fan Yuemin Fan Yang Yang Dong Qian Yue Niu Lizhe An Yun Xiang | 2023 | Journal of Integrative Plant Biology2023，65，7： | 1 |
| 14 | Stability of Sn-Pb mixed organic–inorganic halide perovskite solar cells:Progress,challenges,and perspectives显示文摘The exploration of low bandgap perovskite material to approach Shockley-Queisser limit of photovoltaic device is of great significance,but it is still challenging.During the past few years,tin–lead(Sn-Pb)mixed perovskites with low bandgaps have been rapidly developed,and their single junction solar cells have reached power conversion efficiency(PCE)over 21%,which also makes them ideal candidate as low bandgap sub-cell for tandem device.Nevertheless,due to the incorporation of unstable Sn^(2+),the stability issue becomes the vital problem for the further development of Sn-Pb mixed perovskite solar cells(PSCs).In this review,we are dedicated to give a full view in current understanding on the stability issue of SnPb mixed perovskites and their PSCs.We begin with the demonstration on the origin of instability of Sn-Pb mixed perovskites,including oxidation of Sn^(2+),defects,and interfacial layer induced instability.Sequentially,the up-to-date developments on the stability improvement of Sn-Pb mixed perovskites and their PSCs is systematically reviewed,including composition engineering,additive engineering,and interfacial engineering.At last,the current challenges and future perspectives on the stability study of Sn-Pb mixed PSCs are discussed,which we hope could promote the further application of Sn-Pb mixed perovskites towards commercialization. | Shaoshen Lv Weiyin Gao Yanghua Liu He Dong Nan Sun Tingting Niu Yingdong Xia Zhongbin Wu Lin Song Chenxin Ran Li Fu Yonghua Chen | 2022 | Journal of Energy Chemistry2022，31，2： | 1 |
| 15 | Ionic Liquid for Perovskite Solar Cells:An Emerging Solvent Engineering Technology显示文摘CONSPECTUS:Perovskite solar cells(PSCs)have,in recent years,become one of the most in-depth photovoltaic materials in many different disciplines due to their long-range charge carrier diffusion lengths,strong light absorption,easy tuning of the band gaps,low defect density,and solution processability.The power conversion efficiency(PCE)of single-junction PSCs has reached a certified value of 25.5%,which has caught up with or even surpassed traditional photovoltaic technologies,such as silicon(Si)solar cells,thin film solar cell,etc.In addition to the performance of PSCs comparable to traditional photovoltaic technology,its biggest feature is that it can be prepared by a solution method.The preparation process of the solution method simplify the film preparation process and greatly reduce the preparation cost.In addition,the solution method provides a favorable option for the energy supply of flexible wearable devices in the future. | Lingfeng Chao Tingting Niu Yingdong Xia Yonghua Chen Wei Huang | 2021 | Accounts of Materials Research2021，2，11： | 1 |
| 16 | Constructing Crystalline g-C_(3)N_(4)/g-C_(3)N_(4-x)S_(x)Isotype Heterostructure for Efficient Photocatalytic and Piezocatalytic Performances显示文摘Graphitic carbon nitride(g-C_(3)N_(4))is viewed as a promising visible-light photocatalyst for industrialization due to its low processing temperature and high chemical stability.However,serious charge recombination caused by incomplete polymerization during direct calcination of nitrogen-rich precursors significantly limits its photocatalytic performances.To boost charge separation,herein,we propose a rational strategy by constructing a crystalline g-C_(3)N_(4)/g-C_(3)N_(4-x)S_(x) isotype heterostructure through the molten salt method.Theoretical calculation reveals that apparent charge-transfer channels are formed between g-C_(3)N_(4) and S-doped g-C_(3)N_(4) layers in the heterostructure.Owing to high crystallinity for decreasing charge recombination and isotype heterostructure for efficient charge transfer,the as-prepared g-C_(3)N_(4)/g-C_(3)N_(4-x)S_(x) showed remarkable photocatalytic performances with the hydrogen production rate elevated by up to 12.3 times of its singular components.Another novelty of this work is we investigated for the first time the piezocatalytic activity of crystalline g-C_(3)N_(4) by characterizing its performance for H2O2 generation and KMnO4 reduction.Strikingly,its superior piezocatalytic performance over components can be further improved by NaBH4 treatment,which is uncovered to enhance the asymmetric structure of crystalline g-C_(3)N_(4) by introducing extra cyano groups and removing partial NHx species in its tri-s-triazine layer structure.This work opens up new strategies for the design of highly efficient polymeric photocatalysts and highlights the piezocatalytic studies of g-C_(3)N_(4). | Tingting Xu Zhonghui Xia Hongguan Li Ping Niu Shulan Wang Li Li | 2023 | Energy & Environmental Materials2023，6，2： | 1 |
| 17 | A protocol for the reporting and methodological quality of robotic surgery case reports显示文摘背景:机器人手术是一种复杂且新兴的外科干预方法。近来机器人手术病例报告数量不断增加,但其报告和方法质量尚不清楚。方法:本文采用高特异度检索策略检索PubMed数据库去收集机器人手术相关病例报告,检索时间限定为2012年1月1日至2018年8月1日。用Microsoft Excel 2016生成随机数,并根据我们的纳入标准选择100个合适的机器人手术病例报告。采用数据提取表提取包括第一作者姓名,发表年份,期刊名称等信息。CARE指南和JBI检查表将被分别用于评价纳入病例报告的报告质量和方法学质量。数据提取和质量评价将由独立的两位作者完成,任何分歧将通过讨论或咨询第三个作者解决。同时将根据提取的信息进行分层分析。使用Review Manager 5.3软件(倒方差随机模型)合并与呈现分层分析的结果。结果:该项研究目前正在进行中,未来会将研究结果发表在同行评审的期刊上。结论:本研究将提供机器人手术病例报告的报告质量与方法学质量的证据,并为今后的病例报告提供借鉴与参考,但不仅限于机器人手术病例报告的报告。伦理与传播:由于本研究是基于已发表的机器人手术病例报告文献,因此,不需要伦理审查和患者知情同意。该研究结果将会提交给同行评审的期刊发表。 | Shuguo Niu Ming Liu Cuncun Lu Yuan Yuan Tingting Lu Long Ge Jinhui Tian | 2018 | TMR Clinical Research2018，1，2： | 0 |
| 18 | Dynamic soil arching in piled embankment under train load of high-speed railways显示文摘Piled embankments have many advantages that have been applied in high-speed railway construction engineering.However,the load transfer mechanism of piled embankments,such as soil arching and tension membranes,is still unclear,especially under dynamic loads.To investigate the soil arching and tension membrane under dynamic train loads on high-speed railways,a large-scale piled embankment model test with X-shaped piles as vertical reinforcement was performed,in which twenty-eight earth pressure cells were installed in the piled embankment and an M-shaped wave was adopted to simulate the high-speed railway train load.The results show that dynamic soil arching only occurs when two bogies of a carriage pass by and disappears at other times.The dynamic soil arching and membrane effect are the most significant under the concrete base.The arching height,stress concentration ratio and pile-soil load sharing ratio have a minimal value at 25 Hz.The dynamic soil arching degrades severely at 25 Hz,whose height at 25 Hz is only 0.35 times that at 5 Hz.The arching height fluctuates over a narrow range with increasing loading amplitude.The stress concentration ratio and the pile-soil load sharing ratio increase monotonically as the loading amplitude increases. | Niu Tingting Yang Yule Ma Qianli Zou Jiuqun Lin Bin | 2023 | Earthquake Engineering and Engineering Vibration2023，22，3： | 0 |
| 19 | Theoretical Study on the Hydrogen Bonding Interactions in Complexes of 5-Hydroxytryptamine with Water显示文摘精力,几何学和泛音 1:1 5-hydroxytryptamine-water (5-HT-H2O ) 的震动的频率建筑群在 MP2/6-311++G 被学习(d, p ) 水平。自然债券轨道(NBO ) ,在分子(QTAIM ) 的原子的量子论分析和局部性的分子的轨道的精力分解分析(LMO-EDA ) 被执行在这些建筑群探索结合氢的相互作用的性质。氢契约(H 契约) 的各种各样的类型在这些 5-HT-H2O 建筑群被形成。分子间的 C4H55-HT ?? 嗷在 HTW3 的 H 契约由于 cooperativity 被加强,而没有如此的 cooperativity 在另外的 5-HT-H2O 建筑群被发现。在氮原子的 H 契约在作为质子施主扮演的 5-HT 氨基比另外的 H 契约强壮。我们研究表演结合的相互作用玩的氢 5-HT-H2O 建筑群的相对稳定性上的一个重要角色。 | Lingfei Guo Zhengguo Huang Tingting Shen Lingling Ma Xiqian Niu | 2013 | Chinese Journal of Chemistry2013，31，8： | 0 |
| 20 | Law School of Nankai University Holds International Seminar on National Human Rights Action Plan显示文摘The Information Office of theState council issued the firstNational Human Rights ActionPlan of China (NHRAP)(2009-2010) on April 13, 2009. | NIU TINGTING & DONG YAN | 2009 | The Journal of Human Rights2009，8，4： | 0 |
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