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| 1 | Blunt diaphragmatic lesions: Imaging findings and pitfalls显示文摘Blunt diaphragmatic lesions(BDL) are uncommon in trauma patients, but they should be promptly recognized as a delayed diagnosis increases morbidity and mortality. It is well known that BDL are often overlooked at initial imaging, mainly because of distracting injuries to other organs. Sonography may directly depict BDL only in a minor number of cases. Chest X-ray has low sensitivity in detecting BDL and lesions can be reliably suspected only in case of intra-thoracic herniation of abdominal viscera. Thanks to its wide availability, timeeffectiveness and spatial resolution, multi-detector computed tomography(CT) is the imaging modality of choice for diagnosing BDL; several direct and indirect CT signs are associated with BDL. Given its high tissue contrast resolution, magnetic resonance imaging can accurately depict BDL, but its use in an emergency setting is limited because of longer acquisition times and need for patient's collaboration. | Matteo Bonatti Fabio Lombardo Norberto Vezzali Giulia A Zamboni Giampietro Bonatti | 2016 | World Journal of Radiology2016，8，10： | 5 |
| 2 | CD4+ T cells and natural killer cells: Biomarkers for hepatic fibrosis in human immunodeficiency virus/hepatitis C virus-coinfected patients显示文摘AIM To characterize peripheral blood natural killer(NK) cells phenotypes by flow cytometry as potential biomarker of liver fibrosis in human immunodeficiency virus(HIV)/hepatitis C virus(HCV) coinfected patients.METHODS Peripheral mononuclear cells from 24 HIV/HCV(HBVnegative) coinfected and 5 HIV/HCV/HBV seronegative individuals were evaluated. HIV/HCV coinfected patients were divided in to groups: G1, patients with METAVIR F0-F2 and G2, patients with METAVIR F3-F4. NK surface cell staining was performed with: AntiCD3(APC/Cy7), anti-CD56(PE/Cy5), anti-CD57(APC), anti-CD25(PE), anti-CD69(FITC), anti-NKp30(PE), antiNKp46(PE/Cy7), anti-NKG2D(APC), anti-DNAM(FITC); anti-CD62L(PE/Cy7), anti-CCR7(PE), anti-TRAIL(PE), anti-Fas L(PE), anti CD94(FITC). Flow cytometry data acquisition was performed on BD FACSCanto, analyzed using Flow Jo software. Frequency of fluorescence was analyzed for all single markers. Clinical records were reviewed, and epidemiological and clinical data were obtained.RESULTS Samples from 11 patients were included in G1 and from 13 in G2. All patients were on ARV, with undetectable HIV viral load. Liver fibrosis was evaluated by transient elastography in 90% of the patients and with biopsy in 10% of the patients. Mean HCV viral load was(6.18 ± 0.7 log10). Even though, no major significant differences were observed between G1 and G2 regarding NK surface markers, it was found that patients with higher liver fibrosis presented statistically lower percentage of NK cells than individual with low to mild fibrosis and healthy controls(G2: 5.4% ± 2.3%, G1: 12.6% ± 8.2%, P = 0.002 and healthy controls 12.2% ± 2.7%, P = 0.008). It was also found that individuals with higher liver fibrosis presented lower CD4 LT count than those from G1(G2: 521 ± 312 cells/μL, G1: 770 ± 205 cells/μL; P = 0.035).CONCLUSION Higher levels of liver fibrosis were associated with lower percentage of NK cells and LTCD4+ count; and they may serve as noninvasive biomarkers of liver damage. | Natalia Laufer Diego Ojeda María Laura Polo Ana Martinez Héctor Pérez Gabriela Turk Pedro Cahn Norberto Walter Zwirner Jorge Quarleri | 2017 | World Journal of Hepatology2017，9，25： | 2 |
| 3 | New butenolides in plantlets of Virola surinamensis (Myristicaceae) 显示文摘 | NORBERTO P L PIERRE A D S MASSUO J K | 2004 | Chem Pharm Bull2004，52，10： | 1 |
| 4 | Fenestration of lamina terminalis as a valuable adjunct in aneurysm surgery 显示文摘 | Norberto A Mario Z | 2004 | Neurosurgery2004，55，5： | 1 |
| 5 | Rapid on-site evaluation of thermal comfort through heat capacity in buildings 显示文摘 | Jos6 L Ferntindez Miguel A Porta-Gmindarn Norberto Chargoy | 2005 | Energy and Buildings2005，37，12： | 1 |
| 6 | Cavities determine the pressure unfolding of proteins 显示文摘 | Roche J Caro J A Norberto D R | 2012 | Proc Natl Acad Sci2012，109，18： | 1 |
| 7 | Cognitive impairment in Wilson' s disease 显示文摘 | Norberto A F Paulo C | 2009 | Dementia & Neuropsychologia2009，3，1： | 1 |
| 8 | MICA, a new polymorphic HLA-related antigen, is expressed mainly by keratinocytes, endothelial cells, and monocytes显示文摘 | Norberto W. Zwirner M. A. Fernández-Vi?a Peter Stastny | 1997 | Immunogenetics1997，，2： | 1 |
| 9 | Low-Molecular-Weight Heparin for Prevention of Venous Thromboembolism After Varicose Vein Surgery in Moderate-Risk Patients: A Randomized, Controlled Trial显示文摘 | Enrique María San Norberto García Borja Merino James Taylor Inmaculada Vizcaíno Carlos Vaquero | 2013 | Annals of Vascular Surgery2013，，： | 1 |
| 10 | Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection显示文摘 | Natalia Rubinstein Mariano Alvarez Norberto W Zwirner Marta A Toscano Juan M Ilarregui Alicia Bravo José Mordoh Leonardo Fainboim Osvaldo L Podhajcer Gabriel A Rabinovich | 2004 | Cancer Cell2004，，3： | 1 |
| 11 | Effect of Simultaneous Inhibition of TNF-α Production and Xanthine Oxidase in Experimental Acute Pancreatitis: The Role of Mitogen Activated Protein Kinases显示文摘 | Javier Pereda Luis Sabater Norberto Cassinello Luis Gómez-Cambronero Daniel Closa Emma Folch-Puy Luis Aparisi Julio Calvete Miguel Cerdá Salvador Lledó José Vi?a Juan Sastre | 2004 | Annals of Surgery2004，，1： | 1 |
| 12 | Anterior communicating artery aneu- rysm surgery through the orbitopterional approach: long- term follow-up in a series of 75 consecutive patients 显示文摘 | Norberto A Mario Z | 2008 | Skull Base2008，10，58： | 1 |
| 13 | Cavities determine the pressure unfolding of proteins显示文摘 | Roche J Caro J A Norberto D R | 2012 | Proc Natl Acad Sci U S A2012，109，18： | 1 |
| 14 | Determination of caffeine and its metabolites in urine by capillary electrophoresismass spectrometry显示文摘 | PERI - OKONNY U WANG S X JOHN R S NORBERTO A G | 2005 | Electrophoresis2005，26，13： | 1 |
| 15 | A randomized study comparing ligation with propranolol for primary prophylaxis of variceal bleeding in candidates for liver transplantation显示文摘 | NORBERTO L POLESE L CILLO U GRIGOLETTO F BURROUGHS A K NERI D | 2007 | Liver Transpl2007，13，： | 1 |
| 16 | Characterization of interactions between polyphenolic compounds and human serum proteins by capillary electrophoresis显示文摘 | Andréa Diniz Laura Escuder-Gilabert Norberto P. Lopes Rosa María Villanueva-Cama?as Salvador Sagrado María José Medina-Hernández | 2008 | Analytical and Bioanalytical Chemistry2008，，2： | 1 |
| 17 | Polyphenol-enriched cocoa protects the diabetic retina from glial reaction through the sirtuin pathway显示文摘 | Diego A. Duarte Mariana Ap.B. Rosales Alexandros Papadimitriou Kamila C. Silva Vitor Hugo O. Amancio Jacqueline N. Mendon?a Norberto P. Lopes José B. Lopes de Faria Jacqueline M. Lopes de Faria | 2014 | The Journal of Nutritional Biochemistry2014，，： | 1 |
| 18 | MICA, a new polymorphic HLA-related antigen, is expressed mainly by keratinocytes, endothelial cells, and monocytes显示文摘 | Norberto W. Zwirner M. A. Fernández-Vi?a Peter Stastny | 1997 | Immunogenetics1997，，2： | 1 |
| 19 | Enhancement of Concentration Limits of Detection in CE and CE-MS: A Review of On-line Sample Extraetion, Cleanup, Analyte Preconcentration, and Microreactor Technology显示文摘 | Tomlinson Andy J Guzman Norberto A Naylor Stephen | 1995 | Capillary Electrophoresis1995，2，6： | 1 |
| 20 | Assessment of the exposure to organochlorine pesticides, PCBs and PAHs in six species of predatory birds of the Canary Islands, Spain显示文摘 | Octavio P. Luzardo Norberto Ruiz-Suárez Luis Alberto Henríquez-Hernández Pilar F. Valerón María Camacho Manuel Zumbado Luis D. Boada | 2014 | Science of the Total Environment2014，，： | 1 |
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