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| 1 | Useful detection of CD147 (EMMPRIN) for pathological diagnosis of early hepatocellular carcinoma in needle biopsy samples显示文摘AIM:To make clear whether CD147 (EMMPRIN) expression in pathological tumor samples with a fine-needle aspiration biopsy is useful for pathological diagnosis of early hepatocellular carcinoma (HCC). METHODS:Twenty-two patients (15 men and 7 women; median age 68 years,range 56-81 years) underwent a liver tissue biopsy in order to make a diagnosis of HCC. Paraffin-embedded liver biopsy tissue samples from 22 patients were stained with anti-CD147 antibody,murine monoclonal antibody 12C3 (MAb12C3) for immunohistochemical analysis. An immunohistochemical analysis of CD147 was performed and the degree of staining compared between tumor and non-tumor tissue. In addition,the degree of staining within tumor tissue was compared according to a number of clinicopathological variables. RESULTS:The degree of staining of CD147 was significantly higher in tumor tissues than non-tumor tissues,even in tumors less than 15 mm in diameter.The expression of this protein was significantly elevated in HCC tissue specimens from patients with a low value of serum AST and γ-GTP. | Satoshi Mamori Keisuke Nagatsuma Tomokazu Matsuura Kiyoshi Ohkawa Hiroshi Hano Masaharu Fukunaga Masato Matsushima Yoshifumi Masui Nao Fushiya Hiroshi Onoda Yasuyuki Searashi Ichiro Takagi Hisao Tajiri | 2007 | World Journal of Gastroenterology2007，13，21： | 20 |
| 2 | Survivin expression in early hepatocellular carcinoma and post-treatment with anti-cancer drug under hypoxic culture condition显示文摘瞄准:在肝细胞癌(HCC ) 的早阶段期间调查 survivin 的表示。方法:在肝肿瘤和从 17 个病人拿的非肿瘤织物标本的 survivin 的 Immunohistochemical 表示被比较。另外,在早阶段 HCC 响应反癌症药决定 survivin 表示, survivin 表示在 hypoxic 文化条件下面与反癌症药在 HCC 房间的治疗以后被决定。结果:Survivin 蛋白质在早 HCC 标本在 64.7% 房间被表示。在在 peritumoral hepatocytes 的 survivin 表示率和在 HCC 标本(低率的组对高率的组) 的表示的率之间的关联被观察。在 HCC 房间的 survivin 蛋白质集中被组织缺氧和反癌症药的联合增加。结论:这研究建议 survivin 能在早 HCC 被用作一个治疗学的目标。 | Satoshi Mamori Tadashi Asakura Kiyoshi Ohkawa Hisao Tajiri | 2007 | World Journal of Gastroenterology2007，13，40： | 8 |
| 3 | 陈国达矿(Ag9FeTe2S4):胶东地区金矿床中发现的硫碲化物新矿物显示文摘陈国达矿(Ag9FeTe2S4),产于中国胶东金矿区埠南金矿的含金-银的黄铜矿-石英脉中,呈5~70μm的半自形-他形粒状与方铅矿、黄铜矿、碲银矿、银金矿、自然银、未定名的Ag6TeS2,Ag16FeBiTe3S8共生,并被自然银和螺状硫银矿包围交代.其平均化学成分(16个EPMA分析值)为Ag8.97Fe1.00Te1.99S4.04,理想化学式Ag9FeTe2S4.利用甘多菲照相及同步辐射迴摆照相技术,获得陈国达矿的67个衍射线,主要衍射强线的d值和相对强度(括号中)为:6.742(69),6.416(39),5.951(33),3.265(100),2.981(24),2.649(22),2.25(24),2.188(71),2.142(22),2.123(31),2.044(23),1.949(33).该衍射数据指标化为斜方晶系,a=12.769(2),b=14.814(2),c=16.233(1),V=3070.63,Z=9,dcal=6.85g/cm3.反光显微镜下,陈国达矿的光学性质与硫银锡矿接近,浅灰色,无明显非均质性,摩氏硬度2~3,颜色指数:x=0.3027,y=0.3076,Y=25.78%,λd=474nm,Pe=3.68%.该矿物以中国地质学家、地洼学说的创立人陈国达教授的姓名命名.该矿物及命名经IMA-CNMMN于2004年投票通过.2005年作者补充数据后,由CNMMN主席正式公布,批准号2004-042a。 | 谷湘平 WATANABE Makoto 谢先德 彭省临 NAKAMUTA Yoshihiro OHKAWA Makio HOSHINO Kenichi OHSUMI Kazumasa SHIBATA Yasuhiro | 2008 | 科学通报2008，53，17： | 7 |
| 4 | Pancreaticobiliary maljunction: retrospective and nationwide survey in Japan显示文摘 | Seiki Tashiro T. Imaizumi H. Ohkawa A. Okada T. Katoh Y. Kawaharada H. Shimada H. Takamatsu H. Miyake T. Todani | 2003 | Journal of Hepato - Biliary - Pancreatic Surgery2003，，5： | 4 |
| 5 | Axitinib plus gemcitabine versus placebo plus gemcitabine in patients with advanced pancreatic adenocarcinoma: a double-blind randomised phase 3 study显示文摘 | Hedy L Kindler Tatsuya Ioka Dirk J Richel Jaafar Bennouna Richard Létourneau Takuji Okusaka Akihiro Funakoshi Junji Furuse Young Suk Park Shinichi Ohkawa Gregory M Springett Harpreet S Wasan Peter C Trask Paul Bycott Alejandro D Ricart Sinil Kim Eric Van | 2011 | Lancet Oncology2011，，3： | 4 |
| 6 | Decrease of CD56 + T Cells and Natural Killer Cells in Cirrhotic Livers With Hepatitis C May Be Involved in Their Susceptibility to Hepatocellular Carcinoma显示文摘 | Nobuaki Kawarabayashi Shuhji Seki Kazuo Hatsuse Takashi Ohkawa Yuji Koike Tsukasa Aihara Yoshiko Habu Ryusuke Nakagawa Katsunori Ami Hoshio Hiraide Hidetaka Mochizuki | 2000 | Hepatology2000，，5： | 2 |
| 7 | 630-nm red InGaN micro-light-emitting diodes(<20μm×20μm)exceeding 1 mW/mm~2 for full-color micro-displays显示文摘We demonstrated 10×10 arrays of In Ga N 17μm×17μm micro-light-emitting diodes(μLEDs)with a peak wavelength from 662 to 630 nm at 10–50 A∕cm^(2).The on-wafer external quantum efficiency reached 0.18%at 50 A∕cm^(2).The output power density of the redμLEDs was obtained as 1.76 m W∕mm^(2),which was estimated to be higher than that of 20μm×20μm Al In Ga P redμLEDs(~630 nm).Finally,we demonstrate that In Ga N red/green/blueμLEDs could exhibit a wide color gamut covering 81.3%and 79.1%of the Rec.2020 color space in CIE 1931 and 1976 diagrams,respectively. | ZHE ZHUANG DAISUKE IIDA MARTIN VELAZQUEZ-RIZO KAZUHIRO OHKAWA | 2021 | Photonics Research2021，9，9： | 2 |
| 8 | The role of three dimensional computed tomography in the management of maxiilofacial bone fractures显示文摘 | Ohkawa M Tanabe M Toyama N | 1997 | Acta Med Okayama1997，51，4： | 1 |
| 9 | Effert of Thermal Radiation and Absorption in GaN-MOVPE Growth Modeling on Temperature Distribution and Chemical State显示文摘 | Hirako A Ohkawa K | 2005 | Journal of Crystal Growth2005，276，： | 1 |
| 10 | Intravenous injection of naked plasmid DNA encoding hepatitis B virus (HBV) produces HBV and induces humoral immune response in mice显示文摘 | Suzuki T Takehara T Ohkawa K | 2003 | BBRC2003，300，： | 1 |
| 11 | Micropropagation of garlic through in vitro bulblet formation 显示文摘 | NAGAKUBO T NAGASAWA A OHKAWA H | 1993 | Plant Cell Tissue Orgon Culture1993，32，2： | 1 |
| 12 | Transgenic rice containing human CYP2B6 detoxifies various classes of herbicides 显示文摘 | Hirose S Kawahigashi H Ozawa K Shiota N Inui H Ohkawa H Ohkawa Y | 2005 | Journal of Agricultural and Food Chemistry2005，53，9： | 1 |
| 13 | Comparison of 18F-FLT PET and 18F-FDG PET for preoperative staging in non-small cell lung cancer显示文摘 | Yuka Yamamoto Yoshihiro Nishiyama Naruhide Kimura Shinya Ishikawa Masaya Okuda Shuji Bandoh Nobuhiro Kanaji Masato Asakura Motoomi Ohkawa | 2008 | European Journal of Nuclear Medicine and Molecular Imaging2008，，2： | 1 |
| 14 | Lipiodol accumulation and transarterial chemoembolization efficacy for HCC patients显示文摘 | Kawaguchi T Ohkawa K Imanaka K | | Hepatogastroenterology0，59，113： | 1 |
| 15 | Chitosan nanofiber显示文摘 | Ohkawa K Minato K Kumagai G | 2006 | Biomacromolecules2006，7，11： | 1 |
| 16 | Ultrasmall and ultradense InGaN-based RGB monochromatic micro-light-emitting diode arrays by pixilation of conductive p-GaN显示文摘We describe 5μm squircle InGaN-based red,green,and blue(RGB)monochromatic micro-light-emitting diodes(μLEDs)with an interpitch of 4μm by pixilation of conductive p-GaN using a H2-plasma treatment.The p-GaN was passivated by H2 plasma and prevented the current’s injection into the InGaN quantum wells below.We observed that InGaN-based redμLEDs exhibited a broader full width at half-maximum and larger peak wavelength blueshift at 11.5-115 A/cm^(2) than the green/blueμLEDs.The on-wafer light output power density of the redμLEDs at a wavelength of 632 nm at 115 A/cm^(2) was approximately 936 mW/cm^(2),the highest value reported thus far for InGaN-based redμLEDs.This value was comparable with that of the green/blueμLEDs at 11.5 A/cm^(2),indicating that the redμLEDs can satisfy the requirement of high brightness levels for specific displays.The color gamut based on InGaN RGBμLEDs covered 83.7%to 75.9%of the Rec.2020 color space in the CIE 1931 diagram at 11.5 to 115 A/cm^(2). | ZHE ZHUANG DAISUKE IIDA KAZUHIRO OHKAWA | 2021 | Photonics Research2021，9，12： | 1 |
| 17 | Simultaneous observation of superficial cortical and intracerebral microvessels in vivo during reperfusion after transient forebrain ischemia in rats using synchrotron radiation显示文摘 | Morita M Ohkawa M Miyazaki S | 2007 | Brain Res2007，1158，： | 1 |
| 18 | Localization of hep- aranase in esophageal cancer cells: respective roles in prognosis and differ - entiation 显示文摘 | Ohkawa T Naomoto Y Takaoka M | 2004 | Lab Invest2004，84，10： | 1 |
| 19 | Comparison of 18F-FLT PET and 18F-FDG PET for preoperative staging in non-small cell lung cancer显示文摘 | Yuka Yamamoto Yoshihiro Nishiyama Naruhide Kimura Shinya Ishikawa Masaya Okuda Shuji Bandoh Nobuhiro Kanaji Masato Asakura Motoomi Ohkawa | 2008 | European Journal of Nuclear Medicine and Molecular Imaging2008，，2： | 1 |
| 20 | Oncogenicity of L-type amino-acid transporter 1 (LAT1) revealed by targeted gene disruption in chicken DT40 cells:LAT1 is a promising molecular target for human cancer therapy显示文摘 | Ohkawa M Ohno Y Masuko K | | 0，，04： | 1 |
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