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| 1 | Enhancement patterns of pancreatic adenocarcinoma on conventional dynamic multi-detector row CT:Correlation with angiogenesis and fibrosis显示文摘AIM:To evaluate retrospectively the correlation between enhancement patterns on dynamic computed tomography (CT) and angiogenesis and fibrosis in pancreatic adenocarcinoma.METHODS: Twenty-three patients with pancreatic adenocarcinoma underwent dynamic CT and tumor resection. In addition to the absolute and relative enhanced value that was calculated by subtracting the attenuation value on pre-contrast from those on contrast-enhanced CT in each phase, we defined one parameter, 'tumor-aorta enhancement ratio', which was calculated by dividing enhancement of pancreatic cancer by enhancement of abdominal aorta in each phase. These enhancement patterns were correlated with the level of vascular endothelial growth factor (VEGF), microvessel density (MVD), and extent of fibrosis.RESULTS: The absolute enhanced value in the arterial phase correlated with the level of VEGF and MVD (P=0.047, P=0.001). The relative enhanced value in arterial phase and tumor-aorta enhancement ratio (arterial) correlated with MVD (P=0.003, P=0.022). Tumor-aorta enhancement ratio (arterial) correlated negatively with the extent of fibrosis (P=0.004). The tumors with greater MVD and higher expression of VEGF tended to show high enhancement in the arterial dominant phase. On the other hand, the tumors with a larger amount of fibrosis showed a negative correlation with the grade of enhancement during the arterial phase.CONCLUSION: Enhancement patterns on dynamic CT correlated with angiogenesis and may be modified by the extent of fibrosis. | Yuki Hattori Toshifumi Gabata Osamu Matsui Kentaro Mochizuki Hirohisa Kitagawa Masato Kayahara Tetsuo Ohta Yasuni Nakanuma | 2009 | World Journal of Gastroenterology2009，15，25： | 15 |
| 2 | Phase III study of sorafenib after transarterial chemoembolisation in Japanese and Korean patients with unresectable hepatocellular carcinoma显示文摘 | Masatoshi Kudo Kazuho Imanaka Nobuyuki Chida Kohei Nakachi Won-Young Tak Tadatoshi Takayama Jung-Hwan Yoon Takeshi Hori Hiromitsu Kumada Norio Hayashi Shuichi Kaneko Hirohito Tsubouchi Dong Jin Suh Junji Furuse Takuji Okusaka Katsuaki Tanaka Osamu Matsui | 2011 | European Journal of Cancer2011，，14： | 5 |
| 3 | Feasibility and safety of laparoscopic and endoscopic cooperative surgery for gastric submucosal tumors, including esophagogastric junction tumors显示文摘 | Shu Hoteya Shusuke Haruta Hisashi Shinohara Akihiro Yamada Tsukasa Furuhata Satoshi Yamashita Daisuke Kikuchi Toshifumi Mitani Osamu Ogawa Akira Matsui Toshiro Iizuka Harushi Udagawa Mitsuru Kaise | 2014 | Digestive Endoscopy2014，，4： | 4 |
| 4 | Evidence‐based C linical P ractice G uidelines for H epatocellular C arcinoma: The J apan S ociety of H epatology 2013 update (3rd JSH‐HCC G uidelines)显示文摘 | Norihiro Kokudo Kiyoshi Hasegawa Masaaki Akahane Hiroshi Igaki Namiki Izumi Takafumi Ichida Shinji Uemoto Shuichi Kaneko Seiji Kawasaki Yonson Ku Masatoshi Kudo Shoji Kubo Tadatoshi Takayama Ryosuke Tateishi Takashi Fukuda Osamu Matsui Yutaka Matsuyama Ta | 2015 | Hepatol Res2015，，2： | 2 |
| 5 | Usefulness of Magnifying Endoscopy with Narrow-Band Imaging for Determining Tumor Invasion Depth in Early Gastric Cancer显示文摘 | Daisuke Kikuchi Toshiro Iizuka Shu Hoteya Akihiro Yamada Tsukasa Furuhata Satoshi Yamashita Kaoru Domon Masanori Nakamura Akira Matsui Toshifumi Mitani Osamu Ogawa Sumio Watanabe Mitsuru Kaise Guido Schumacher | 2013 | Gastroenterology Research and Practice2013，，： | 2 |
| 6 | Superselective transarterial chemoembolization for hepatocellular carcinoma. Validation of treatment algorithm proposed by Japanese guidelines显示文摘 | Kenichi Takayasu Shigeki Arii Masatoshi Kudo Takafumi Ichida Osamu Matsui Namiki Izumi Yutaka Matsuyama Michiie Sakamoto Osamu Nakashima Yonson Ku Norihiro Kokudo Masatoshi Makuuchi | 2011 | Journal of Hepatology2011，，4： | 2 |
| 7 | Endoscopic submucosal dissection for nonampullary large superficial adenocarcinoma/adenoma of the duodenum: feasibility and long-term outcomes显示文摘 | Shu Hoteya Naohisa Yahagi Toshiro Iizuka Daisuke Kikuchi Toshifumi Mitani Akira Matsui Osamu Ogawa Satoshi Yamashita Tsukasa Furuhata Akihiro Yamada Ryusuke Kimura Kosuke Nomura Yasutaka Kuribayashi Mitsuru Kaise | 2013 | EIO2013，，01： | 2 |
| 8 | Rebamipide, a Gastroprotective Drug, Inhibits Indomethacin-Induced Apoptosis in Cultured Rat Gastric Mucosal Cells: Association with the Inhibition of Growth Arrest and DNA Damage-Induced 45α Expression显示文摘 | Yuji Naito Hirokazu Kajikawa Katsura Mizushima Makoto Shimozawa Masaaki Kuroda Kazuhiro Katada Tomohisa Takagi Osamu Handa Satoshi Kokura Hiroshi Ichikawa Norimasa Yoshida Hirofumi Matsui Toshikazu Yoshikawa | 2005 | Digestive Diseases and Sciences2005，，1： | 2 |
| 9 | Corrigendum to: “Comparison of resection and ablation for hepatocellular carcinoma: A cohort study based on a Japanese nationwide survey” [J Hepatol 2013;58:724–729]显示文摘 | Kiyoshi Hasegawa Norihiro Kokudo Masatoshi Makuuchi Namiki Izumi Takafumi Ichida Masatoshi Kudo Yonson Ku Michiie Sakamoto Osamu Nakashima Osamu Matsui Yutaka Matsuyama | 2013 | Journal of Hepatology2013，，： | 2 |
| 10 | Delayed bleeding after endoscopic submucosal dissection for non‐ampullary superficial duodenal neoplasias might be prevented by prophylactic endoscopic closure: Analysis of risk factors显示文摘 | Shu Hoteya Mitsuru Kaise Toshiro Iizuka Osamu Ogawa Toshifumi Mitani Akira Matsui Daisuke Kikuchi Tsukasa Furuhata Satoshi Yamashita Akihiro Yamada Ryusuke Kimura Kousuke Nomura Yasutaka Kuribayashi Yoshifumi Miyata Naohisa Yahagi | 2015 | Digestive Endoscopy2015，，3： | 2 |
| 11 | Interventional oncology: new options for interstitial treatments and intravascular approaches显示文摘 | Osamu Matsui Shiro Miyayama Jyun-ichiro Sanada Satoshi Kobayashi Wataru Khoda Tetsuya Minami Kazuto Kozaka Toshifumi Gabata | 2010 | Journal of Hepato-Biliary-Pancreatic Sciences2010，，4： | 2 |
| 12 | Rotavirusinfection among infants with diarrhea in Pakistan显示文摘 | Osamu Nishio Nikhiko Matsui Tomohiro Oka | | PediatricsInternational0，42，： | 1 |
| 13 | Antitumor Activity of Lenvatinib (E7080): An Angiogenesis Inhibitor That Targets Multiple Receptor Tyrosine Kinases in Preclinical Human Thyroid Cancer Models显示文摘 | Osamu Tohyama Junji Matsui Kotaro Kodama Naoko Hata-Sugi Takayuki Kimura Kiyoshi Okamoto Yukinori Minoshima Masao Iwata Yasuhiro Funahashi Giovanni Tallini | 2014 | Journal of Thyroid Research2014，，： | 1 |
| 14 | Rotavirus infection among infants with diarrhea in Pakistan 显示文摘 | Osamu Nshio Kiyohiko Matsui Tomohiro Oka | 2000 | Pediatrics International2000，，42： | 1 |
| 15 | Rotavirus infection among infants with diarrhea in Pakistan显示文摘 | Osamu Nishio Kiyohiko Matsui Tomohiro Oka | 2000 | Pediatrics International2000，42，： | 1 |
| 16 | Prospective Study about the Utility of Endoscopic Ultrasound for Predicting the Safety of Endoscopic Submucosal Dissection in Early Gastric Cancer (T-HOPE 0801)显示文摘 | Daisuke Kikuchi Toshiro Iizuka Shu Hoteya Akihiro Yamada Tsukasa Furuhata Satoshi Yamashita Kaoru Domon Masanori Nakamura Akira Matsui Toshifumi Mitani Osamu Ogawa Mitsuru Kaise Everson L. A. Artifon | 2013 | Gastroenterology Research and Practice2013，，： | 1 |
| 17 | Hepatic pseudolymphoma: imaging–pathologic correlation with special reference to hemodynamic analysis显示文摘 | Kotaro Yoshida Satoshi Kobayashi Osamu Matsui Toshifumi Gabata Junichiro Sanada Wataru Koda Tetsuya Minami Yasuji Ryu Kazuto Kozaka Azusa Kitao | 2013 | Abdominal Imaging2013，，6： | 1 |
| 18 | Efficacy of Covered Metallic Stents in the Treatment of Unresectable Malignant Biliary Obstruction显示文摘 | Shiro Miyayama Osamu Matsui Yukari Akakura Toru Yamamoto Hiroto Nishida Kenji Yoneda Keiichi Kawai Daisyu Toya Nobuyoshi Tanaka Takeshi Mitsui Yasuyuki Asada | 2004 | CardioVascular and Interventional Radiology2004，，： | 1 |
| 19 | Endothelial to Mesenchymal Transition via Transforming Growth Factor-β1/Smad Activation Is Associated with Portal Venous Stenosis in Idiopathic Portal Hypertension显示文摘 | Azusa Kitao Yasunori Sato Seiko Sawada-Kitamura Kenichi Harada Motoko Sasaki Hiroyasu Morikawa Susumu Shiomi Masao Honda Osamu Matsui Yasuni Nakanuma | 2009 | The American Journal of Pathology2009，，2： | 1 |
| 20 | Comparison of resection and ablation for hepatocellular carcinoma: A cohort study based on a Japanese nationwide survey显示文摘 | Kiyoshi Hasegawa Norihiro Kokudo Masatoshi Makuuchi Namiki Izumi Takafumi Ichida Masatoshi Kudo Yonson Ku Michiie Sakamoto Osamu Nakashima Osamu Matsui Yutaka Matsuyama | 2012 | Journal of Hepatology2012，，： | 1 |
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